研究等業績 - その他 - 齋藤　満

Factors influencing warm ischemia time in robot-assisted partial nephrectomy change depending on the surgeon’s experience

Numakura K.

World Journal of Surgical Oncology ( World Journal of Surgical Oncology )  20 ( 1 )   2022年12月

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Effects of NR1I2 and ABCB1 Genetic Polymorphisms on Everolimus Pharmacokinetics in Japanese Renal Transplant Patients

Yagishita H.

International Journal of Molecular Sciences ( International Journal of Molecular Sciences )  23 ( 19 )   2022年10月

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Severe Immune-Related Adverse Events in Patients Treated with Nivolumab for Metastatic Renal Cell Carcinoma Are Associated with PDCD1 Polymorphism

Kobayashi M.

Genes ( Genes )  13 ( 7 )   2022年07月

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Specific Gut Microbial Environment in Lard Diet-Induced Prostate Cancer Development and Progression

Sato H.

International Journal of Molecular Sciences ( International Journal of Molecular Sciences )  23 ( 4 )   2022年02月

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Advanced Tertiary Lymphoid Tissues in Protocol Biopsies are Associated with Progressive Graft Dysfunction in Kidney Transplant Recipients

李 有鎬, 佐藤 有紀, 齋藤 満, 福間 真悟, 齋藤 雅也, 山本 恵則, 小松田 敦, 藤山 信弘, 佐藤 滋, 羽渕 友則, 柳田 素子

Journal of the American Society of Nephrology ( American Society of Nephrology (ASN) )  33 ( 1 ) 186 - 200   2022年01月

[Background:] Tertiary lymphoid tissues (TLTs) are ectopic lymphoid tissues found in chronically inflamed organs. Although studies have documented TLT formation in transplanted kidneys, the clinical relevance of these TLTs remains controversial. We examined the impacts of TLTs on future graft function using our histological TLT maturity stages and the association between TLTs and Banff pathologic scores. We also analyzed the risk factors for the development of TLTs. [Methods:] Serial protocol biopsy samples (0-hour, 1-, 6-, and 12-months) without rejection were retrospectively analyzed from 214 patients who underwent living donor kidney transplantation. TLTs were defined as lymphocyte aggregates with signs of proliferation and their stages were determined by the absence (stage I) or presence (stage II) of follicular dendritic cells. [Results:] Only 4% of patients exhibited TLTs at the 0-hour biopsy. Prevalence increased to almost 50% at the 1-month biopsy and then slightly further for 12 months. The proportion of advanced stage II TLTs increased gradually, reaching 19% at the 12-month biopsy. Presence of stage II TLTs was associated with higher risk of renal function decline after transplantation compared to patients with no TLT or stage I TLTs. Stage II TLTs were associated with more severe tubulitis and interstitial fibrosis/tubular atrophy at 12 months and predicted poorer graft function independently from the degree of interstitial inflammation. Pre-transplantation rituximab treatment dramatically attenuated the development of stage II TLTs. [Conclusions:] TLTs are commonly found in clinically stable transplanted kidneys. Advanced stage II TLTs are associated with progressive graft dysfunction, independent of interstitial inflammation.

CiNii Research

Advanced Tertiary Lymphoid Tissues in Protocol Biopsies are Associated with Progressive Graft Dysfunction in Kidney Transplant Recipients

Lee Y.H.

Journal of the American Society of Nephrology ( Journal of the American Society of Nephrology )  33 ( 1 ) 186 - 200   2022年01月

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Comparison of parenchymal volume loss assessed by three-dimensional computed tomography volumetry and renal functional recovery between conventional and robot-assisted laparoscopic partial nephrectomy

Kanda S.

Asian journal of endoscopic surgery ( Asian journal of endoscopic surgery )  15 ( 1 ) 63 - 69   2022年01月

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Effect of Levofloxacin on the Efficacy and Adverse Events in Intravesical Bacillus Calmette-Guerin Treatment for Bladder Cancer: Results of a Randomized, Prospective, Multicenter Study

Numakura K.

European Urology Focus ( European Urology Focus )    2022年

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Impact of germline HLA genotypes on clinical outcomes in patients with urothelial cancer treated with pembrolizumab

Takahashi S.

Cancer Science ( Cancer Science )    2022年

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Impact of trough abiraterone level on adverse events in patients with prostate cancer treated with abiraterone acetate

Takahashi Y.

European Journal of Clinical Pharmacology ( European Journal of Clinical Pharmacology )    2022年

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Altering phosphoinositides in high-fat diet-associated prostate tumor xenograft growth

Huang M.

MedComm ( MedComm )  2 ( 4 ) 756 - 764   2021年12月

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SUCCESSFUL RE-ADMINISTRATION OF NIVOLUMAB IN PATIENT WITH METASTATIC RENAL CELL CARCINOMA: A CASE REPORT

Sasagawa H.

Acta Urologica Japonica ( Acta Urologica Japonica )  67 ( 12 ) 525 - 528   2021年12月

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Tacrolimus concentrations after renal transplantation in a mother-neonate dyad: Maternal, neonatal and breast milk measurements

Akamine Y.

Journal of Clinical Pharmacy and Therapeutics ( Journal of Clinical Pharmacy and Therapeutics )  46 ( 6 ) 1800 - 1803   2021年12月

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ニボルマブ再投与で治療効果を示した転移性腎細胞癌の1例

笹川 甫, 沼倉 一幸, 中村 岳, 久木元 隆, 菊池 茜恵, 提箸 隆一郎, 山本 竜平, 小泉 淳, 奈良 健平, 神田 壮平, 齋藤 満, 成田 伸太郎, 井上 高光, 佐藤 滋, 羽渕 友則

泌尿器科紀要 ( 泌尿器科紀要刊行会 )  67 ( 12 ) 525 - 528   2021年12月

A 46-year-old woman was referred to our hospital with a left-sided renal tumor pointed out by ultrasonography at the time of a medical checkup．Computed tomography revealed a mass measuring 88×77×68 mm on the upper pole of the left kidney. She was diagnosed with cT2aN0M0 clear cell renal cell carcinoma. Laparoscopic left nephrectomy was performed uneventfully. Histopathological diagnosis was clear cell renal cell carcinoma, G2, v1, pT2. Four months after surgery, lung metastases appeared, and systemic therapy was given sequentially as follows ; sunitinib for 2 months, nivolumab for 8 months, axitinib for 17 months, and pazopanib for 2 months．However, metastases progressed, and a re-administration of nivolumab was planned. The nivolumab re-treatment resulted in a marked reduction in multiple lung metastases despite the previous failure by nivolumab treatment. There are few reports on the therapeutic effect of re-administration of nivolumab. We report a case of successful treatment by re-administration of nivolumab.

DOI CiNii Research

Incidence, etiology, prevention and management of ureteroenteric strictures after robot-assisted radical cystectomy: A review of published evidence and personal experience

Narita S.

Current Oncology ( Current Oncology )  28 ( 5 ) 4109 - 4117   2021年10月

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特集 今こそ知りたい!　ロボット時代の腹腔鏡手術トレーニング-腹腔鏡技術認定を目指す泌尿器科医のために〈特別付録Web動画〉 〈腹腔鏡技術認定を目指した取り組み〉 腎移植を積極的に行う施設でのトレーニング法

齋藤 満, 成田 伸太郎, 羽渕 友則

臨床泌尿器科 ( 株式会社医学書院 )  75 ( 10 ) 730 - 735   2021年09月

DOI CiNii Research

Anaphylaxis Induced by Intravenous Tacrolimus Administration During Kidney Transplant Surgery: A Case Report

Yamamoto R.

Transplantation Proceedings ( Transplantation Proceedings )  53 ( 4 ) 1292 - 1294   2021年05月

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ロボット支援腎部分切除術における腎実質縫合の有無による術後腎実質体積のCT volumetryを用いた比較検討

提箸 隆一郎, 井上 高光, 中島 志織, 嘉島 相輝, 山本 竜平, 小泉 淳, 奈良 健平, 神田 壮平, 沼倉 一幸, 齋藤 満, 成田 伸太郎, 佐藤 滋, 羽渕 友則

Japanese Journal of Endourology ( 日本泌尿器内視鏡学会 )  34 ( 1 ) 130 - 135   2021年

<p>【目的】ロボット支援腎部分切除術 (RAPN) における腎実質縫合の追加が術後の腎実質体積を減少させるかを画像解析ソフトにより検討した. また腎機能, 合併症への影響も検討した.</p><p>【対象と方法】2013年11月から2018年11月までに当科でRAPNを行ったT1a症例69例のうち, 腎実質縫合を施行した26例 (実質縫合群) と省略した43例 (非縫合群) を後方視的に比較した. Synapse Vincent ver. 4を用いて, 術前と術後6カ月の造影CTから腎実質減少体積を推定した.</p><p>【結果】2群間の患者背景や手術成績に有意差はなかった. 腎実質体積の減少量やeGFRの低下率, 合併症の発生率に有意差を認めなかった.</p><p>【結語】RAPNにおける腎実質縫合の追加は腎実質体積や腎機能, 合併症の発生に影響しなかった.</p>

DOI CiNii Research

上部尿路上皮癌に対するロボット支援腹腔鏡下腎尿管全摘除術の経験

齋藤 満, 成田 伸太郎, 沼倉 一幸, 嘉島 相輝, 山本 竜平, 小泉 淳, 奈良 健平, 羽渕 友則

Japanese Journal of Endourology ( 日本泌尿器内視鏡学会 )  34 ( 2 ) 318 - 322   2021年

<p>　今回我々はロボット支援腹腔鏡下腎尿管全摘除術 (RNU) の初期経験を得た.</p><p>　対象は2019年7月から2020年7月にda Vinci Si (4例) またはXi (2例) サージカルシステムでRNUを受けた6症例. 全例男性で患側は左4例, 右2例, cT3の3例を含む4例で術前化学療法を施行した. 完全側臥位, 軽度ジャックナイフ体位, 6または7ポート, 経腹膜アプローチで手術を施行した. 術中, 体位変換やペイシェントカートの移動は行わなかった.</p><p>　手術時間の中央値は308分, 推定出血量の中央値は63 mLで輸血や開腹手術移行は無かった. pT3の左尿管癌症例1例で摘出標本断端が陽性であった. 周術期合併症はClavien-dindo分類でGrade Ⅱの乳糜腹水, 下痢を1例ずつ認めた.</p><p>　RNUは手術手技の標準化とより多くの症例を対象とした長期追跡調査が必要であるが, UTUC症例に対する新たな治療選択肢となり得る.</p>

DOI CiNii Research

First-line axitinib therapy is less effective in metastatic renal cell carcinoma with spindle histology

Numakura K.

Scientific Reports ( Scientific Reports )  10 ( 1 )   2020年12月

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