Research Achievements - Original paper -
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Early Lymph Node Metastasis May Predict Poor Prognosis in Soft Tissue Sarcoma
Emori M.
International Journal of Surgical Oncology ( International Journal of Surgical Oncology ) 2019 2019
Research paper (journal)
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Impact of acridine orange in patients with soft tissue sarcoma treated with marginal resection
Tsuchie H.
Anticancer Research ( Anticancer Research ) 39 ( 11 ) 6365 - 6372 2019
Research paper (journal)
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Impact of spinal kyphosis on gastric myoelectrical activity in elderly patients with osteoporosis
Tsuchie H.
Biomedical Research (Japan) ( Biomedical Research (Japan) ) 40 ( 6 ) 215 - 223 2019
Research paper (journal)
<p>An association between spinal kyphosis and gastroesophageal reflux disease (GERD) was reported in recent years. However, it remains unclear whether spinal kyphosis affects gastric motility. We evaluated the changes in myoelectrical activity measured by electrogastrography (EGG) in elderly osteoporosis patients. A total of 18 patients scheduled for the treatment of osteoporosis were included in this study. They were analyzed by recording EGG to assess myoelectrical activity and heart rate variability (HRV) to evaluate the autonomic nervous system function before and after meals. Dominant power (DP) representing the strength of gastric electrical activity and dominant frequency (DF) representing its frequency were analyzed in blocks with a 5-minute duration. We divided the patients into 2 groups, thoracolumbar kyphosis (TLK) and non-TLK groups, and compared them. There were no significant differences between the 2 groups in background data. In the non-TLK group, DPs post 0–5 min were significantly higher than those during pre 5–0 min in channels 1 and 3 (<i>P</i> < 0.05 and <i>P</i> < 0.01). DF deviation in the TLK group was significantly higher than that in the non-TLK group at 10 to 15 postprandial minutes (<i>P</i> < 0.05). Low frequency/high frequency activity measured by HRV, reflecting the activity of the sympathetic nervous system, in the TLK group was significantly lower than that in the non-TLK group while eating (<i>P</i> < 0.01). The EGG of patients with spinal kyphotic deformity showed a similar change to that of patients with GERD; the spinal kyphotic deformity itself may affect gastric electrical activity.</p>
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Tani T.
Advances in Orthopedics ( Advances in Orthopedics ) 2019 2019
Research paper (journal)
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Kasukawa Y.
Clinical Interventions in Aging ( Clinical Interventions in Aging ) 14 1399 - 1405 2019
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Ono Y.
Biomedical Research (Japan) ( Biomedical Research (Japan) ) 40 ( 5 ) 197 - 205 2019
Research paper (journal)
<p>We investigated the effects of ibandronate, a bisphosphonate; eldecalcitol, an active vitamin D3 analogue; and combination treatment with both agents on secondary osteoporosis and arthritis using rats with adjuvant-induced arthritis. Arthritis was induced in 8-week-old male Lewis rats. Rats were randomized into four treatment groups and an untreated normal control group: ibandronate, eldecalcitol, ibandronate + eldecalcitol, vehicle, and control. Paw thickness was measured to evaluate arthritis. Joint destruction was evaluated histomorphometrically by the ankle joint stained with Fast Green and safranin O. The femur and lumbar spine were scanned using dual-energy X-ray absorptiometry, and the distal femur was scanned using micro-computed tomography for bone mineral density (BMD) and trabecular microstructural evaluations. Ibandronate and/or eldecalcitol increased BMD in both the lumbar vertebrae and femur and improved several microstructural parameters (bone volume/total volume, structure model index, trabecular number, and trabecular separation of the distal femur). In addition, there was an additive effect of combination treatment compared with single treatments for most trabecular parameters, including BMD and bone volume. However, ibandronate and/or eldecalcitol did not inhibit arthritis and joint destruction. Combination treatment with ibandronate and eldecalcitol may be effective for secondary osteoporosis associated with arthritis.</p>
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Prognostic impact of CD44 expression in patients with myxofibrosarcoma
Tsuchie H.
In Vivo ( In Vivo ) 33 ( 6 ) 2095 - 2102 2019
Research paper (journal)
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Kasukawa Y.
Asian Spine Journal ( Asian Spine Journal ) 13 ( 5 ) 832 - 841 2019
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Kamo K.
Advances in Orthopedics ( Advances in Orthopedics ) 2019 2019
Research paper (journal)
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Matsunaga Toshiki, Miyakoshi Naohisa, Kudo Daisuke, Saito Kimio, Kimura Ryota, Inoue Junichi, Chida Satoaki, Hatakeyama Kazutoshi, Shimada Yoichi
The Japanese Journal of Rehabilitation Medicine ( The Japanese Association of Rehabilitation Medicine ) 56 ( 7 ) 555 - 559 2019
Research paper (journal)
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A case of lymphangiomatosis causing cervical vertebral fracture
MITA Motoki, MIYAKOSHI Naohisa, TSUCHIE Hiroyuki, SHIMADA Yoichi
Journal of the Eastern Japan Association of Orthopaedics and Traumatology ( The Eastern Japan Association of Orthopaedics and Traumatology ) 31 ( 4 ) 468 - 472 2019
Research paper (journal)
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Osteoporosis and Therapeutic Exercise
Miyakoshi Naohisa
The Japanese Journal of Rehabilitation Medicine ( The Japanese Association of Rehabilitation Medicine ) 56 ( 5 ) 367 - 370 2019
Research paper (journal)
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MIURA Takanori, TANI Takayuki, KIJIMA Hiroaki, EBINA Toshihito, MIYAKOSHI Naohisa, SHIMADA Yoichi
Journal of the Eastern Japan Association of Orthopaedics and Traumatology ( The Eastern Japan Association of Orthopaedics and Traumatology ) 31 ( 1 ) 66 - 69 2019
Research paper (journal)
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Posterior spinal fusion using a unilateral C1 posterior arch screw and a C2 laminar screw for atlantoaxial fracture dislocation.
Yuichi Ono, Naohisa Miyakoshi, Michio Hongo, Yuji Kasukawa, Yoshinori Ishikawa, Daisuke Kudo, Ryota Kimura, Jumpei Iida, Yoichi Shimada
SAGE open medical case reports 7 2050313X19849276 2019
Research paper (journal)
INTRODUCTION: C1 lateral mass screws and C2 pedicle screws are usually chosen to fix atlantoaxial (C1-C2) instability. However, there are a few situations in which these screws are difficult to use, such as in a case with a fracture line at the screw insertion point and bleeding from the fracture site. A new technique using a unilateral C1 posterior arch screw and a C2 laminar screw combined with a contralateral C1 lateral mass screws-C2 pedicle screws procedure for upper cervical fixation is reported. CASE REPORT: A 24-year-old woman had an irreducible C1-C2 anterior dislocation with a type III odontoid fracture on the right side due to a traffic accident. The patient underwent open reduction and posterior C1-C2 fixation. On the left side, a C1 lateral mass screws and a C2 pedicle screws were placed. Because there was bleeding from the fracture site and a high-riding vertebral artery was seen on the right side, a C1 posterior arch screw and a C2 laminar screw were chosen. Eight months after the surgery, computed tomography scans showed healing of the odontoid fracture with anatomically correct alignment. CONCLUSIONS: Although there have been few comparable studies, fixation with unilateral C1 posterior arch screw-C2 laminar screw could be a beneficial choice for surgeries involving the upper cervical region in patients with fracture dislocation or arterial abnormalities.
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Age-related prevalence of periodontoid calcification and its associations with acute cervical pain
Kobayashi T.
Asian Spine Journal ( Asian Spine Journal ) 12 ( 6 ) 1117 - 1122 2018.12
Research paper (journal)
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Tsuchie H.
Osteoporosis International ( Osteoporosis International ) 29 ( 12 ) 2659 - 2665 2018.12
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Saito H.
Knee Surgery and Related Research ( Knee Surgery and Related Research ) 30 ( 4 ) 293 - 302 2018.12
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Traumatic intratumoral hemorrhage of schwannoma of the cauda equina: A report of two cases
Kimura R.
Journal of Orthopaedic Science ( Journal of Orthopaedic Science ) 23 ( 6 ) 1105 - 1109 2018.11
Research paper (journal)
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Akagawa M.
PLoS ONE ( PLoS ONE ) 13 ( 10 ) e0204857 2018.10
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Suzuki N.
Journal of Orthopaedic Science ( Journal of Orthopaedic Science ) 23 ( 5 ) 849 - 852 2018.09
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