Research Achievements - Original paper -
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Miyakoshi N.
Spinal Cord ( Spinal Cord ) 2020
Research paper (journal)
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Miyakoshi N.
Surgical Neurology International ( Surgical Neurology International ) 11 2020
Research paper (journal)
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Fujii M.
Journal of Orthopaedic Science ( Journal of Orthopaedic Science ) 2020
Research paper (journal)
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Inoue Gen, Taguchi Toshihiko, Haro Hirotaka, Taneichi Hiroshi, Yamazaki Masashi, Nishida Kotaro, Yamada Hiroshi, Kabata Daijiro, Shintani Ayumi, Iwasaki Motoki, Ito Manabu, Kaito Takashi, Miyakoshi Naohisa, Murakami Hideki, Yonenobu Kazuo, Takura Tomoyuki, Mochida Joji, Matsuyama Yukihiro, Yamashita Toshihiko, Kawakami Mamoru, Takahashi Kazuhisa, Yoshida Munehito, Imagama Shiro, Ohtori Seiji
Spine Surgery and Related Research ( 一般社団法人 日本脊椎脊髄病学会 ) 2020
Research paper (journal)
<p><b>Introduction: </b>Chronic low back pain (CLBP) is a leading cause of disability, yet there is limited high-quality evidence to identify the most suitable pharmacological therapy. The purpose of this Japanese nationwide, multicenter, prospective study was to compare the effectiveness of four representative drug therapies—acetaminophen, celecoxib, loxoprofen, and a tramadol and acetaminophen (T+A) combination drug—to establish evidence for a drug of choice for CLBP.</p><p><b>Methods: </b>Patients with CLBP (N = 471) received one of the four treatments and were evaluated, prospectively and comprehensively, once every month for six months using a visual analog scale (VAS) for LBP, the Japanese Orthopedic Association (JOA) score, the JOA Back Pain Evaluation Questionnaire (JOABPEQ), the Roland–Morris Disability Questionnaire (RDQ), the EuroQol five-dimensions three-levels (EQ-5D-3L), and the Short Form-8 item health survey (SF-8). We conducted multivariable linear regression analyses of the four drugs at 1 and 6 months after drug allocation. Differences with P < 0.05 were considered statistically significant.</p><p><b>Results: </b>Patients who received acetaminophen showed a significant improvement from baseline in the mental health subscale of the JOABPEQ at one month (<i>P</i> = 0.02) and the JOA score at six months (<i>P</i> < 0.01). None of the other outcome measures among the four drugs differed significantly. Across groups, all outcome measures, except the mental component summary (MCS) score of the SF-8, improved equivalently, although most measurements showed no obvious cumulative effect over six months. The MCS score of the SF-8 decreased gradually over six months in all groups.</p><p><b>Conclusions: </b>Most of the outcome measures among the treated groups were not significantly different, indicating similar treatment effects of the four drugs for CLBP. Our study indicated the limit of each outcome measure for evaluating the patient status, suggesting that a single outcome measure is insufficient to reflect treatment effectiveness.</p>
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Miyakoshi Naohisa, Masutani Norimitsu, Kasukawa Yuji, Kudo Daisuke, Saito Kimio, Matsunaga Toshiki, Shimada Yoichi
Progress in Rehabilitation Medicine ( 公益社団法人 日本リハビリテーション医学会 ) 5 ( 0 ) 2020
Research paper (journal)
<p><b>Objectives: </b>Previous studies have suggested that the effects of vitamin D in preventing osteoporotic fractures result in part from its influence on fall prevention. However, the effects of vitamin D on dynamic balance as a contributor to fall prevention have not been fully evaluated. Moreover, few studies have compared the effects of native and active forms of vitamin D. The objective of this preliminary randomized prospective study was to compare the effects of native vitamin D and eldecalcitol on muscular strength and dynamic balance in postmenopausal patients undergoing denosumab treatment for osteoporosis.</p><p><b>Methods: </b>A total of 30 women with postmenopausal osteoporosis were randomly assigned to a native D group (administered denosumab and native vitamin D with calcium) or an ELD group (administered denosumab and eldecalcitol) and were followed up for 6 months. The following parameters were compared: the strengths of the back extensor and lower extremity muscles; static balance evaluated using the one-leg standing test; and dynamic balance evaluated using the 10-m walk test, the functional reach test, the timed up and go test, and the total length of the trajectory of the center of gravity (LNG) measured using a dynamic sitting balance measurement device.</p><p><b>Results: </b>Compared to baseline measurements, back extensor and knee extensor strengths had significantly increased after 6 months of treatment in the native D group (P<0.05) but not in the ELD group. In contrast, LNG significantly improved in both groups after 6 months (P<0.05). No significant differences between the two groups were seen in any of these measured parameters after treatment.</p><p><b>Conclusions: </b>Both native vitamin D + denosumab and eldecalcitol + denosumab were effective for improving dynamic sitting balance in postmenopausal women with osteoporosis.</p>
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Diagnosis of presarcopenia using body height and arm span for postmenopausal osteoporosis
Ono Y.
Clinical Interventions in Aging ( Clinical Interventions in Aging ) 15 357 - 361 2020
Research paper (journal)
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Effectiveness of Ilizarov external fixation in elderly patients with pilon fractures
Nozaka K.
Journal of Orthopaedic Science ( Journal of Orthopaedic Science ) 2020
Research paper (journal)
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Okuyama K.
Acta Orthopaedica et Traumatologica Turcica ( Acta Orthopaedica et Traumatologica Turcica ) 54 ( 6 ) 647 - 650 2020
Research paper (journal)
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Imagama S.
Journal of Orthopaedic Science ( Journal of Orthopaedic Science ) 2020
Research paper (journal)
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Kudo D.
Journal of Back and Musculoskeletal Rehabilitation ( Journal of Back and Musculoskeletal Rehabilitation ) 33 ( 2 ) 263 - 268 2020
Research paper (journal)
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Initial Rotational Instability of the Tapered Wedge-Shaped Type Cementless Stem
Iwamoto Y.
Advances in Orthopedics ( Advances in Orthopedics ) 2020 2020
Research paper (journal)
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Kasukawa Yuji, Miyakoshi Naohisa, Hongo Michio, Ishikawa Yoshinori, Kudo Daisuke, Kimura Ryota, Ono Yuichi, Shimada Yoichi
Progress in Rehabilitation Medicine ( 公益社団法人 日本リハビリテーション医学会 ) 5 ( 0 ) 2020
Research paper (journal)
<p><b>Objectives: </b>The extent to which locomotive syndrome is associated with low back pain (LBP), health-related quality of life (HRQOL), and impairment of activities of daily living among elderly men and women remains poorly documented. This study evaluated associations between locomotive syndrome and both HRQOL and LBP as assessed using a questionnaire completed by elderly individuals, including some >80 years old.</p><p><b>Methods: </b>We conducted a survey assessing locomotive syndrome using the loco-check, HRQOL using the Short-Form 36 questionnaire (SF-36), and LBP using the Roland-Morris Disability Questionnaire (RDQ) among individuals >60 years old. SF-36 and RDQ scores were compared between 253 subjects with and without locomotive syndrome.</p><p><b>Results: </b>Fifty-seven men (48%) and 71 women (53%) were diagnosed with locomotive syndrome. Subjects of both sexes with locomotive syndrome scored significantly lower for eight items from SF-36. Physical and mental component summary scores were significantly worse in women with locomotive syndrome in their 60s and 70s. RDQ scores were significantly higher in participants with locomotive syndrome for men in their 60s and for both men and women in their 70s.</p><p><b>Conclusions: </b>Locomotive syndrome was associated with impaired HRQOL and worse LBP among men and women >60 years old. Differences in HRQOL and LBP between subjects with and without locomotive syndrome were significant for both men and women in their 60s and 70s, but not in their 80s. Locomotive syndrome should be prevented to maintain HRQOL, particularly for men and women in their 60s and 70s.</p>
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Tsuchie H.
Medical principles and practice : international journal of the Kuwait University, Health Science Centre ( Medical principles and practice : international journal of the Kuwait University, Health Science Centre ) 29 ( 6 ) 538 - 543 2020
Research paper (journal)
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Kikuchi K.
Journal of Orthopaedic Science ( Journal of Orthopaedic Science ) 2020
Research paper (journal)
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Relationship between Dynamic Trunk Balance and the Balance Evaluation Systems Test in Elderly Women
Takahashi Yasuhiro, Saito Kimio, Matsunaga Toshiki, Iwami Takehiro, Kudo Daisuke, Tate Kengo, Miyakoshi Naohisa, Shimada Yoichi
Progress in Rehabilitation Medicine ( 公益社団法人 日本リハビリテーション医学会 ) 5 ( 0 ) 2020
Research paper (journal)
<p><b>Objective</b>: Falls are major contributors to elderly subjects becoming bedridden. Consequently, it is important to evaluate and minimize the risk of falls in the elderly. Trunk stability is important for balance function and is related to fall prevention in elderly women. We developed a balance-measuring device that uses a dynamic sitting position to safely measure balance function. The Balance Evaluation Systems Test (BESTest) is useful method to assess balance function, a recently developed balance evaluation test that can detect minor balance problems not captured by previous tests. The purpose of the present study was to examine the relationship between dynamic trunk balance and findings of the BESTest in elderly women. <b>Methods</b>: Thirty-one healthy women aged 60 years or more participated in this study. The evaluation items were the BESTest total score, scores for each of the six elements of the BESTest, dynamic sitting balance, static postural balance, and muscle strength. <b>Results</b>: The mean total BESTest score was 85.4 points. The mean total trajectory length of the center of gravity (COG) during the dynamic sitting balance test was 1447.5 mm. A negative correlation (r=–0.481, P= 0.006) was observed between the total COG trajectory length and the BESTest score. A negative correlation was also found between the total COG trajectory length and biomechanical constraints (r=–0.492, P=0.005) and anticipatory postural adjustments (r=–0.532, P=0.002). There were no correlations between the dynamic sitting balance total COG trajectory length and the stationary standing COG trajectory length or muscle strength. <b>Conclusions</b>: In elderly women, the total COG trajectory length during dynamic sitting was negatively correlated with the BESTest total score.</p>
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Spinal Cord Compression with Occult Bony Fragment in Osteoporotic Vertebral Fracture: A Case Report
Ishikawa Yoshinori, Miyakoshi Naohisa, Hongo Michio, Kasukawa Yuji, Kudo Daisuke, Shimada Yoichi
Spine Surgery and Related Research ( 一般社団法人 日本脊椎脊髄病学会 ) 2020
Research paper (journal)
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The Differences in Imaging Findings Between Painless and Painful Osteoarthritis of the Hip
Kijima H.
Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders ( Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders ) 13 2020
Research paper (journal)
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Cohort Study of Rheumatoid Arthritis in Japan
Kashiwagura Takeshi, Aonuma Hiroshi, Kawano Tetsuya, Miyakoshi Naohisa, Shimada Yoichi
The Japanese Journal of Rehabilitation Medicine ( The Japanese Association of Rehabilitation Medicine ) 57 ( 11 ) 1054 - 1061 2020
Research paper (journal)
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Post-operative outcomes of distal radius fractures for the late-stage elderly patients
YUASA Yusuke, SENMA Seietsu, NARITA Yuichiro, ITO Hiroki, MIYAKOSHI Naohisa, SHIMADA Yoichi
Journal of the Eastern Japan Association of Orthopaedics and Traumatology ( The Eastern Japan Association of Orthopaedics and Traumatology ) 32 ( 4 ) 570 - 573 2020
Research paper (journal)
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MIURA Takanori, EBINA Toshihito, TANI Takayuki, CHIDA Shuichi, MIYAKOSHI Naohisa, SHIMADA Yoichi
Journal of the Eastern Japan Association of Orthopaedics and Traumatology ( The Eastern Japan Association of Orthopaedics and Traumatology ) 32 ( 1 ) 112 - 116 2020
Research paper (journal)