Research Achievements - Original paper -

An advanced ultrasound application used to assess peripheral vascular diseases: superb microvascular imaging

Sato W.

Journal of Echocardiography ( Journal of Echocardiography )  19 ( 3 ) 150 - 157   2021.09  [Refereed]  [Invited]

Research paper (journal)   Domestic Co-author

DOI

Thrombosed sinus of Valsalva aneurysm masquer ading as a cardiac tumour: A case report

Sato W.

European Heart Journal - Case Reports ( European Heart Journal - Case Reports )  5 ( 8 )   2021.08  [Refereed]

Research paper (journal)   Domestic Co-author

DOI Repository

Clinical implications of local impedance measurement using the IntellaNav MiFi OI ablation catheter: an ex vivo study

Hidehiro Iwakawa,Masateru Takigawa,Masahiko Goya,Toyoto Iwata,Claire A Martin,Tatsuhiko Anzai,Kunihiko Takahashi,Miki Amemiya,Tasuku Yamamoto,Masahiro Sekigawa,Yasuhiro Shirai,Susumu Tao,Tatsuya Hayashi,Yoshihide Takahashi,Hiroyuki Watanabe,Tetsuo Sasano

Journal of Interventional Cardiac Electrophysiology ( Journal of Interventional Cardiac Electrophysiology )  63 ( 1 ) 185 - 195   2021.01  [Refereed]

Research paper (journal)   Domestic Co-author

DOI

B38-CAP is a bacteria-derived ACE2-like enzyme that suppresses hypertension and cardiac dysfunction

Minato T.

Nature Communications ( Nature Communications )  11 ( 1 )   2020.12  [Refereed]

Research paper (journal)   Domestic Co-author

DOI

医療過疎地域における植込み型心臓電気デバイス装着遺体の火葬時の取扱い

佐藤 誠, 藤原 優人, 加澤 隆康, 北嶋 久寛, 珍田 優奈, 渡部 健一, 藤田 美幸, 渡邊 博之

心臓 ( 公益財団法人 日本心臓財団 )  52 ( 12 ) 1368 - 1372   2020.12  [Refereed]

Research paper (journal)   Domestic Co-author

<p>　ペースメーカなどの植込み型心臓電気デバイス装着遺体の火葬に関する対応は統一されていない．そこで我々は2018年9月より病院死亡，在宅・介護施設死亡にかかわらず，死亡確認後に医師はデバイス摘出は行わずに「デバイス証明」を遺族に渡すこと，行政窓口では埋火葬許可証内に追加したペースメーカ装着の有無欄をチェックするという方法で統一した．運用開始後1年間で14例すべてのデバイス植込み症例の情報が火葬場職員に確実に伝達され，トラブルなく火葬がなされた．</p>

DOI CiNii Research

Cardiac emerinopathy: A nonsyndromic nuclear envelopathy with increased risk of thromboembolic stroke due to progressive atrial standstill and left ventricular noncompaction

Taisuke Ishikawa, Hiroyuki Mishima,Julien Barc,Masanori P. Takahashi,Keiichi Hirono,Shigenori Terada,Shinya Kowase,Teruki Sato,Yasushi Mukai,Yoshiaki Yui,Kimie Ohkubo,Hiroki Kimoto,Hiroyuki Watanabe, Yukiko Hata,Takeshi Aiba,Seiko Ohno,Akiko Chishaki, Wataru Shimizu,Minoru Horie,Fukiko Ichida,Akihiko Nogami,Koh Ichiro Yoshiura,Jean Jacques Schott,Naomasa Makita

Circulation: Arrhythmia and Electrophysiology ( Circulation: Arrhythmia and Electrophysiology )  13 ( 10 ) 1165 - 1174   2020.10  [Refereed]

Research paper (journal)  

DOI

m⁶A demethylase ALKBH5 promotes proliferation of esophageal squamous cell carcinoma associated with poor prognosis

Nagaki Y.

Genes to Cells ( Genes to Cells )  25 ( 8 ) 547 - 561   2020.08  [Refereed]

Research paper (journal)   Domestic Co-author

DOI

Association of Obesity with Prevalence of White-coat and Sustained Hypertension in Young Adults

Kobayashi Masao,Sato Wakana,Tashiro Haruwo,Namura Ikuro,Fushimi Masahito,Watanabe Hiroyuki

秋田医学 ( 秋田医学会 )  47 ( 1 ) 31 - 38   2020.06  [Refereed]

Research paper (journal)  

Purpose : This study was performed to determine whether obesity is associated with white-coat hypertension (WHT) and sustained hypertension (SHT) in young adults.
Methods : Blood pressure (BP) was measured at home by university students (n=95) who exhibited BP readings ≥ 140/90 mmHg during their annual health exam and post-exam measurements between 2005 and 2014. Subject characteristics and BP readings from the WHT and SHT groups were compared to those of normotensive (NT) subjects.
Results : The mean body-mass index (BMI) was higher in both the WHT (p<0.05) and SHT groups (p<0.01) compared to the NT group, and the mean BMI in the SHT group was higher (p<0.01) than the WHT group. The ratio of WHT to NT subjects in the obese group (BMI ≥ 30) was higher than in the normal weight group (18.5 ≤ BMI < 25) (p<0.05). The ratio of SHT to NT subjects in the obese group was higher than in the normal weight and overweight groups (25 ≤ BMI < 30) (each, p<0.01).
Conclusion : Obesity is associated with both WHT and SHT in university students, which suggests that maintaining a healthy weight is important for the management of WHT and SHT in young adults.

DOI Repository

Renal blood circulation as a manifestation of systemic atherosclerosis

Takako Iino,Hiroyuki Watanabe

Internal Medicine ( Internal Medicine )  59 ( 7 ) 885 - 886   2020.04  [Refereed]

Research paper (journal)  

DOI

Manifestation of coronary subclavian steal phenomenon using reactive hyperemia in the ipsilateral forearm

Iino T.

Echocardiography ( Echocardiography )  36 ( 10 ) 1956 - 1958   2019.10  [Refereed]

Research paper (journal)   Domestic Co-author

DOI

Visualization of arterial wall vascularization using superb microvascular imaging in active-stage Takayasu arteritis

Sato W.

European Heart Journal Cardiovascular Imaging ( European Heart Journal Cardiovascular Imaging )  20 ( 6 )   2019.06  [Refereed]

Research paper (journal)   Domestic Co-author

DOI

Urinary D-serine level as a predictive biomarker for deterioration of renal function in patients with atherosclerotic risk factors

Iwakawa H.

Biomarkers ( Biomarkers )  24 ( 2 ) 159 - 165   2019.02  [Refereed]

Research paper (journal)   Domestic Co-author

DOI

Loss of apelin augments angiotensin ii-induced cardiac dysfunction and pathological remodeling

Sato T.

International Journal of Molecular Sciences ( International Journal of Molecular Sciences )  20 ( 2 )   2019.01  [Refereed]

Research paper (journal)   Domestic Co-author

DOI

Validity of ultrasound lungcomets for assessment of the severity of interstitial pneumonia

Asano M.

Journal of Ultrasound in Medicine ( Journal of Ultrasound in Medicine )  37 ( 6 ) 1523 - 1531   2018.06  [Refereed]

Research paper (journal)   Domestic Co-author

DOI

Morphological determinants of obstructive hypertrophic cardiomyopathy obtained using echocardiography

Nara I.

International Heart Journal ( International Heart Journal )  59 ( 2 ) 339 - 346   2018.03  [Refereed]

Research paper (journal)   Domestic Co-author

<p>The morphological determinants of left ventricular outflow tract (LVOT) obstruction in hypertrophic cardiomyopathy (HCM) are not completely understood. We aimed to identify the anatomical risks of the obstruction using echocardiography.</p><p>Fifty patients with untreated HCM were classified into two groups: those with LVOT pressure gradient (LVOTPG) ≥ 30 mmHg (obstructive HCM [HOCM] group) and those with LVOTPG < 30 mmHg (HNCM group). The echocardiographic morphological variables were analyzed to determine whether they were predictive of LVOT obstruction. Systolic anterior motions of the mitral valve were observed in 100% of patients in the HOCM group but only in 58% in the HNCM group. There were no significant differences in wall thickness, end-systolic LV dimension (LVDs), or LVOT diameter between the two groups. However, HOCM subjects had a shorter distance from papillary muscles to the inter-ventricular septum (5.97 ± 2.3 versus 9.20 ± 1.9 mm, respectively, <i>P</i> < 0.0001) and a longer anterior mitral leaflet (AML) length (24.7 ± 5.8 versus 20.1 ± 5.4 mm, respectively, <i>P</i> < 0.01) compared to the HNCM group. The AML length/LVDs ratio was significantly higher in the HOCM group compared to the HNCM group (1.02 ± 0.34 versus 0.78 ± 0.26, <i>P</i> < 0.01), and an LVOT obstruction was predicted with an area under the curve of 0.71 (<i>P</i> < 0.05). Multiple linear regression revealed that only the AML length/LVDs ratio was independently associated with LVOTPG (<i>P</i> < 0.01).</p><p>The AML length/LVDs ratio has a significant predictive value for LVOT obstruction and a strong relationship with LVOTPGs. The AML length/LVDs ratio determines the anatomical risk of LVOT obstruction in HCM.</p>

DOI

The CCR4-NOT deadenylase complex controls atg7-dependent cell death and heart function

Yamaguchi T.

Science Signaling ( Science Signaling )  11 ( 516 )   2018.02  [Refereed]

Research paper (journal)   Domestic Co-author

DOI

Simultaneous appearance of intracardiac masses following chemotherapy in a patient with lung cancer

Shimbo M.

European Heart Journal Cardiovascular Imaging ( European Heart Journal Cardiovascular Imaging )  19 ( 1 )   2018.01  [Refereed]

Research paper (journal)   Domestic Co-author

DOI

A cardiac calcified amorphous tumor associated with end-stage renal disease: An emerging disease concept

Watanabe H.

Internal Medicine ( Internal Medicine )  56 ( 22 ) 2967 - 2968   2017.11  [Refereed]

Research paper (journal)   Domestic Co-author

DOI

Inflammatory aneurysm of ileocolic artery discovered on fluorine 18-fluorodeoxyglucose-positron emission tomography/computed tomography

Sato W.

Journal of Vascular Surgery ( Journal of Vascular Surgery )  66 ( 5 ) 1574 - 1575   2017.11  [Refereed]

Research paper (journal)   Domestic Co-author

DOI

Stromal interaction molecule 1 haploinsufficiency causes maladaptive response to pressure overload

Ohba T.

PLoS ONE ( PLoS ONE )  12 ( 11 )   2017.11  [Refereed]

Research paper (journal)   Domestic Co-author

DOI