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Affiliation |
Hospital Division of Clinical Pathology |
Graduating School 【 display / non-display 】
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-1988.03
Akita University Faculty of Medicine Graduated
Graduate School 【 display / non-display 】
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-1993.03
Akita University Graduate School, Division of Medicine Doctor's Course Completed
Campus Career 【 display / non-display 】
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2003.04-Now
Akita University Hospital Division of Clinical Pathology Associate Professor
Research Achievements 【 display / non-display 】
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4times in situ transient one-hour flow decrease can induce intimal thickening and medial remodeling of flow-remodeled artery
Nanjo， H.， Komatsu， M.， Masuda， H， et al
Microcirculation annual 19 45 - 46 2003.01
Research paper (journal) Domestic Co-author
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Ultrastructure of endothelial cells under flow alteration
Masuda， H.， Kawamura， K.， Nanjo， H.， et al
Microsc Res Tech 60 2 - 12 2003.01
Research paper (journal) Domestic Co-author
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High flow derives vascular endothelial cell proliferation during flow-inducued arterial remodeling associated with the expression of vascular endothelial growth factors
Sho， E.， Komatsu， M.， Nanjo， H.， et al
Experimental and Molecular Pathology 75 1 - 11 2003.01 [Refereed]
Research paper (journal) Domestic Co-author
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Efficacy of continuous infusion of prostaglandin E1 through the superior mesenteric artery against ischemic liver cell necrosis after hepatic artery occlusion
Kato， T.， Sato， T.， Kurokawa， T.， Nanjo， H.， et al:
Transplantation 76 1340 - 1345 2003.01 [Refereed]
Research paper (journal) Domestic Co-author
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Durability test of microtome blades in sectioning of bone tissue embedded samples
Satoh Hirotaka, Nakamae Keito, Sasaki Takehiro, Nanjo Hiroshi, Akagami Yoichi, Nakamura Ryuta, Kusumi Takayuki, Yoshino Masahiko
Proceedings of JSPE Semestrial Meeting ( The Japan Society for Precision Engineering ) 2023A ( 0 ) 762 - 763 2023.08
<p>This paper reports the results of an investigation into the durability of microtome blades used for sectioning pathological samples. We conducted repeated sectioning experiments at a constant set thickness with automatic sectioning equipment we developed, using paraffin blocks embedded with porcine rib tissue as samples. We measured changes in cutting force and damage to the blade edge and examined the effects on the tissue quality of sections.</p>
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A Case of Renal Anastomosing Hemangioma
SASAKI Yoshiki, KASHIMA Soki, KOYAMA Takashi, HIROSHIMA Yuko, AMANO Kenji, TAKAHASHI Syuhei, NARA Taketoshi, KOIZUMI Atsushi, YAMAMOTO Ryohei, NUMAKURA Kazuyuki, SAITO Mitsuru, NARITA Shintaro, NANJO Hiroshi, SATOH Shigeru, HABUCHI Tomonori
68 ( 8 ) 265 - 269 2022.08
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Durability test of microtome blade for tissue sectioning
Satoh Hirotaka, Nakamae Keito, Nakagawa Yuki, Nanjo Hiroshi, Akagami Yoichi, Nakamura Ryuta, Kusumi Takayuki, Yoshino Masahiko
Proceedings of JSPE Semestrial Meeting ( The Japan Society for Precision Engineering ) 2022A ( 0 ) 278 - 279 2022.08
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Study of cutting force and section thickness for pathological diagnosis
Satoh Hirotaka, Kitamura Shunsuke, Nakagawa Yuuki, Nanjo Hiroshi, Akagami Yoichi, Nakamura Ryuta, Kuzumi Takayuki, Yoshino Masahiko
Proceedings of JSPE Semestrial Meeting ( The Japan Society for Precision Engineering ) 2022S ( 0 ) 503 - 504 2022.03
<p>For pathological diagnosis of cancer and other diseases, it is necessary to embed diseased tissues in paraffin and cut them into sections that have thickness of several micrometers to get preparations for microscopic observation. In this study, we aim to improve and stabilize the quality of pathological sections. In this paper, we will report the results of experimental measurements of cutting force and thickness of pathological sections of various specimen-embedded paraffin blocks and the investigation of factors affecting the cutting force and thickness based on mechanical model.</p>
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METASTATIC Mucinous Tubular and Spindle Cell Carcinoma Treated with Nivolumab Successfully : A Case Report
Takahashi Yoshiko, Numakura Kazuyuki, Aoyama Yu, Okada Shuhei, Saito Takuro, Muto Yumina, Koizumi Atsushi, Nara Taketoshi, Chiba Syuji, Kanda Sohei, Saito Mitsuru, Narita Shintaro, Inoue Takamitsu, Satoh Shigeru, Nanjo Hiroshi, Habuchi Tomonori
65 ( 9 ) 363 - 367 2019.09
A 68-year-old man was referred to our hospital with a right-sided renal tumor identified by ultrasonography at the time of his medical check-up. Computed tomography revealed a well-circumscribed but distorted mass measuring 64×45×57 mm in the right kidney with para-aortic lymph node swelling. Laparoscopic right nephrectomy with para-aortic lymphadenectomy was performed. Histopathological diagnosis was mucinous tubular and spindle cell carcinoma (MTSCC) (pT3a) without lymph node metastasis (pN0). Postoperatively, metastases were identified in the lungs, and the vertebral and iliac bones. The patient was treated with axitinib. The lung nodule progressed and left sacrum metastases appeared even after treatment with axitinib. Therefore, nivolumab was administered as second-line treatment. The metastases in the lungs, as well as vertebral and iliac bone showed complete response to this therapy. MTSCC of the kidney is a rare low-grade renal cell carcinoma without any established systemic therapy for metastatic or unresectable lesions. We report a case of metastatic MTSCC in a patient who showed a favorable response to nivolumab treatment. This is the first report to describe successful treatment of metastatic MTSCC with anti-programmed cell death 1 antibody.