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Affiliation |
Hospital Orthopedic Surgery |
Graduating School 【 display / non-display 】
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-1994.03
Akita University Faculty of Medicine Graduated
Graduate School 【 display / non-display 】
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-1999.03
Akita University Graduate School,Division of Medicine Doctor's Course Completed
Campus Career 【 display / non-display 】
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2005.04-Now
Akita University Hospital Orthopedic Surgery Assistant Professor
External Career 【 display / non-display 】
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2010.01
Akita University
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2007.04
Akita University University Hospital, Orthopedic Surgery Assistant Professor
Academic Society Affiliations 【 display / non-display 】
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1994-Now
Japan
THE JAPANESE ORTHOPAEDIC ASSOCIATION
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2016-2021
Japan
THE JAPANESE ASSOCIATION OF REHABILITATION MEDICINE
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1996-Now
Japan
JAPANESE SOCIETY FOR BONE AND MINERAL RESEARCH
Research Areas 【 display / non-display 】
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Life Science / Orthopedics
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Life Science / Orthopedics / 骨軟部腫瘍
Thesis for a degree 【 display / non-display 】
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Effect of retinoic acid on murine preosteoblastic MC3T3-E1 cells
Nagasawa H, Takahashi S, Kobayashi A, Tazawa H, Tashima Y, Sato K
Journal of Nutritional Science and Vitaminology 51 311 - 318 1999.03 [Refereed]
Domestic Co-author
Research Achievements 【 display / non-display 】
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Effect of Zoledronic Acid Administration Timing on Metastatic Bone Tumors
Watanabe M.
In Vivo Athens Greece ( In Vivo Athens Greece ) 39 ( 4 ) 1984 - 1991 2025.07 [Refereed]
Research paper (journal) Domestic Co-author
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Teriparatide Does Not Exacerbate Bone Metastases in Breast Cancer Bone Metastasis Model
Kawaragi T.
In Vivo Athens Greece ( In Vivo Athens Greece ) 39 ( 4 ) 1932 - 1940 2025.07 [Refereed]
Research paper (journal) Domestic Co-author
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Surgical Treatment and Prognosis of Soft Tissue Sarcoma in Patients Aged 85 Years and Older
Tsuchie H.
In Vivo ( In Vivo ) 39 ( 3 ) 1661 - 1668 2025.05 [Refereed]
Research paper (journal) Domestic Co-author
BACKGROUND/AIM: The incidence of soft tissue sarcomas (STSs) among older patients is increasing. Although it has been reported that surgical treatment of elderly patients with STS improves prognosis, most of these studies included patients aged <85 years. This study aimed to analyze the clinical features and prognostic factors of STS in excessively elderly patients aged ≥85 or ≥90 years. PATIENTS AND METHODS: We retrospectively identified 398 patients with STS who were treated at our two hospitals between 1994 and 2022. Only histological types that existed in ≥20 cases were included. Data on clinical information and detailed assessments were collected. We divided the patients into two subgroups according to 85 or 90 years of age and compared the groups within each subgroup. Furthermore, we examined the factors affecting the prognosis of all and older patients. RESULTS: Patients ≥85 or ≥90 years old comprised 12.1% and 4.0% of the study population, respectively. In all patients, Kaplan-Meier curves for overall survival demonstrated a significantly poorer prognosis in elderly patients with STS aged ≥85 years (p=0.0476) and ≥90 years (p=0.0164). However, no significant differences were observed when analyzing only patients who underwent surgical treatment without distant metastasis at diagnosis. In the multivariate analyses, surgical treatment for the primary tumor improved prognosis exclusively in patients ≥85 years old (p =0.0300). CONCLUSION: Surgical treatment improves the prognosis in elderly STS patients aged ≥85 years and possibly among those aged ≥90 years.
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Isolated Talar Metastasis of Renal Cell Carcinoma Treated With Tibiocalcaneal Arthrodesis Using an Ilizarov External Fixation.
Shuichi Chida, Koji Nozaka, Hiroyuki Tsuchie, Hiroyuki Nagasawa, Naohisa Miyakoshi
Cureus 17 ( 1 ) e77275 2025.01 [Refereed]
Research paper (journal) Domestic Co-author
Acrometastases to the feet are exceedingly rare. We report a case of isolated talar metastasis from renal cell carcinoma successfully managed through surgical excision and reconstruction with Ilizarov external fixation. A 65-year-old male presented with a six-month history of right ankle pain. Radiographs revealed an osteolytic lesion in the talus. An incisional biopsy confirmed the diagnosis of metastatic renal cell carcinoma. Systemic evaluation showed no recurrence in the right kidney or metastases beyond the right talus. En bloc resection of the talus was performed via an anterior approach, followed by tibiocalcaneal arthrodesis using Ilizarov external fixation. At the four-year follow-up, the patient remained pain-free while walking and showed no evidence of recurrence or additional metastases.
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Tsuchie H.
Medical Principles and Practice ( Medical Principles and Practice ) 34 ( 6 ) 593 - 601 2025 [Refereed]
Research paper (journal) Domestic Co-author
UNLABELLED: <p>Objectives: Unplanned excision (UE) of soft tissue sarcoma (STS) impacts recurrence and prognosis, influenced by various factors. However, few studies have thoroughly analyzed these patients. This study aimed to comprehensively evaluate prognostic factors in patients with STS who underwent UE. SUBJECT AND METHODS: We retrospectively identified 62 patients with STS who underwent UE. Data on clinical information and detailed assessment were collected. Clinical data were evaluated as risk factors for overall survival, local recurrence, and distant metastases. Furthermore, associations of influencing factors and survival outcomes were analyzed. RESULTS: Multivariate analysis identified consultation after local recurrence following previous surgery and histological high grade as significant predictors of poor prognosis (p = 0.0390 and p = 0.0282, respectively). Histological high grade was the only risk factor for distant metastasis (p = 0.0173). Kaplan-Meier curves demonstrated significant differences in overall survival based on the presence or absence of local recurrence at referral after UE (p = 0.0476, p = 0.0022). The use of local anesthetics in previous surgeries was the only risk factor for consultation after local recurrence. CONCLUSION: Referral after local recurrence after UE and histological high grade were poor prognostic factors. Physicians must be aware that patients with UE should be referred to specialists promptly. </p>.
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70 ( 1 ) 1 - 3 2019.01 [Refereed]
Introduction and explanation (commerce magazine) Domestic Co-author
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Yuasa Y, Miyakoshi N, Kasukawa Y, Nagahata I, Akagawa M, Ono Y, Sato C, Tsuchie H, Nozaka K, Nagasawa H, Hongo M, Shimada Y
Journal of bone and mineral metabolism 38 ( 2 ) 179 - 187 2020.03
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Treatment outcome of chest wall soft tissue sarcomas: Analysis of prognostic factors.
Nakahashi N, Emori M, Tsuchie H, Nagasawa H, Sonoda T, Takada K, Miyajima M, Watanabe A, Shimada Y, Yamashita T
Journal of surgical oncology 120 ( 7 ) 1235 - 1240 2019.12
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Tsuchie H, Emori M, Nagasawa H, Miyakoshi N, Murahashi Y, Shimizu J, Mizushima E, Yamashita T, Shimada Y
Medical principles and practice : international journal of the Kuwait University, Health Science Centre 28 ( 5 ) 425 - 431 2019.09
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Costal osteomyelitis as a side reaction of Bacillus Calmette-Guérin vaccination: A case report
WAKABAYASHI Rena, MIYAKOSHI Naohisa, TSUCHIE Hiroyuki, NAGASAWA Hiroyuki, SHIMADA Yoichi
Journal of the Eastern Japan Association of Orthopaedics and Traumatology ( The Eastern Japan Association of Orthopaedics and Traumatology ) 31 ( 4 ) 483 - 486 2019
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Impact of Acridine Orange in Patients With Soft Tissue Sarcoma Treated With Marginal Resection.
Tsuchie H, Emori M, Miyakoshi N, Nagasawa H, Okada K, Murahashi Y, Mizushima E, Shimizu J, Yamashita T, Shimada Y
Anticancer research 39 ( 11 ) 6365 - 6372 2019
◆Original paper【 display / non-display 】
◆Introduction and explanation【 display / non-display 】
◆Other【 display / non-display 】
Grant-in-Aid for Scientific Research 【 display / non-display 】
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Effects of intravascular administration of acridine orange and bisphosphonate in a local bone metastasis of breast cancer model
Grant-in-Aid for Scientific Research(C)
Project Year： 2019.04 - 2022.03 Investigator(s): Tsuchie Hiroyuki
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Effects of intravascular administration of acridine orange and bisphosphonate in a local bone metastasis of breast cancer model
Grant-in-Aid for Scientific Research(C)
Project Year： 2019.04 - 2022.03 Investigator(s): Tsuchie Hiroyuki
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The effect of intravascular administration of acridine orange on multiple metastases of carcinoma
Grant-in-Aid for Scientific Research(C)
Project Year： 2024.04 - 2027.03
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Effects of intravascular administration of acridine orange and bisphosphonate in a local bone metastasis of breast cancer model
Grant-in-Aid for Scientific Research(C)
Project Year： 2019.04 - 2022.03 Investigator(s): Tsuchie Hiroyuki
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Grant-in-Aid for Scientific Research(C)
Project Year： 2019.04 - 2022.03