Research Interests 【 display / non-display 】

Research Interests 【 display / non-display 】

Graduating School 【 display / non-display 】

Graduating School 【 display / non-display 】

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  1992.03

  Tohoku Pharmaceutical University   Faculty of Pharmaceutical Science   Graduated

Graduate School 【 display / non-display 】

Graduate School 【 display / non-display 】

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  1994.03

  Tohoku Pharmaceutical University  Graduate School, Division of Pharmaceutical Sciences  Master's Course  Completed

Campus Career 【 display / non-display 】

Campus Career 【 display / non-display 】

• 2021.12

  -

  Now

  Akita University   Graduate School of Medicine   Doctorial Course in Medicine   Bioregulatory Medicine   Department of Pharmacokinetics   Professor  

• 2013.04

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  2021.11

  Akita University   Hospital   Department of Pharmacy   Professor  

Research Achievements 【 display / non-display 】

Research Achievements 【 display / non-display 】

◆Original paper【 display / non-display 】

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◆Original paper【 display / non-display 】

Influence of UGT1A7 and UGT1A9 intronic I399 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients

Masatomo,Miura

Ther Drug Monit   29 ( 299 ) 304   2007.01

Research paper (journal)   Single author

Influence of UGT1A8 and UGT2B7 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients

Masatomo,Miura

Eur J Clin Pharmacol   63 ( 279 ) 288   2007.01  [Refereed]

Research paper (journal)   Single author

Determination of fexofenadine enantiomers in human plasma with high-performance liquid chromatography

Masatomo,Miura

J Pharm Biomed Anal   43 ( 741 ) 745   2007.01

Research paper (journal)   Single author

Pharmacokinetics of fexofenadine enantiomers in healthy subjects

Masatomo,Miura

Chirality   19 ( 223 ) 227   2007.01

Research paper (journal)   Single author

To the head of this page.▲

◆Other【 display / non-display 】

To the head of this page.▲

◆Other【 display / non-display 】

Efficacy of alectinib for ALK-positive anaplastic large cell lymphoma with central nervous system relapse after allogeneic bone marrow transplantation

Yano Mio, Tamura Shinichi, Tomoyasu Chihiro, Nakamura Sayaka, Mori Takeshi, Soejima Toshinori, Iijima-Yamashita Yuka, Horibe Keizo, Miura Masatomo, Ishida Hiroyuki

The Japanese Journal of Pediatric Hematology / Oncology ( The Japanese Society of Pediatric Hematology / Oncology )  63 ( 1 ) 56 - 60   2026

<p>A 10-year-old boy was diagnosed with central nervous system (CNS) relapse of ALK-positive anaplastic large cell lymphoma (ALCL). Despite reinduction therapy and whole-brain and spinal cord proton beam irradiation, followed by allogeneic bone marrow transplantation, molecular relapse occurred at 12 weeks post-transplantation. CNS relapse of ALCL remains a therapeutic challenge because of limited drug delivery to the CNS and the lack of established treatment strategies. In this case, initiation of oral alectinib with intrathecal injection of hydrocortisone and cytarabine and withdrawal of immunosuppressants led to renewed negativity for <i>NPM::ALK</i> fusion via polymerase chain reaction analysis. Moreover, the patient remained in complete remission four years after transplantation. These results suggest that alectinib with favorable cerebrospinal fluid penetration is potentially effective for CNS diseases. Therefore, incorporating alectinib into treatment strategies may improve long-term outcomes in CNS-relapsed ALK-positive ALCL. Future studies, including pharmacokinetic evaluations, should optimize its application in relapsed/refractory cases.</p>

DOI CiNii Research

Comparison of Serum Vancomycin Concentrations using a New Automated Analyzer based on High-Performance Liquid Chromatography and Chemiluminescent Immunoassay

Akamine Yumiko, Matsushita Miyuki, Morikawa Satoru, Miura Masatomo

Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences) ( Japanese Society of Pharmaceutical Health Care and Sciences )  51 ( 4 ) 187 - 195   2025.04

DOI CiNii Research

Simultaneous Determination of Serum Concentrations of Phenytoin and Carbamazepine with LM1010 High-Performance Liquid Chromatography and Comparison with CLIA

Akamine Yumiko, Matsushita Miyuki, Morikawa Satoru, Miura Masatomo

Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences) ( Japanese Society of Pharmaceutical Health Care and Sciences )  50 ( 9 ) 465 - 472   2024.09

DOI CiNii Research

Overexposure to venetoclax is associated with prolonged-duration of neutropenia during venetoclax and azacitidine therapy in Japanese patients with acute myeloid leukemia

Kobayashi Takahiro, Honami Sato, Miura Masatomo, Fukushi Yayoi, Kuroki Wataru, Ito Fumiko, Teshima Kazuaki, Watanabe Atsushi, Fujishima Naohito, Kobayashi Isuzu, Kameoka Yoshihiro, Takahashi Naoto

Cancer Chemotherapy and Pharmacology ( Springer Nature )    2024

CiNii Research

Evaluation of Plasma Concentrations of Mycophenolic Acid in Renal Transplant Patients Using LM1010 High-performance Liquid Chromatography

Akamine Yumiko, Matsushita Miyuki, Morikawa Satoru, Miura Masatomo

YAKUGAKU ZASSHI ( The Pharmaceutical Society of Japan )  143 ( 4 ) 377 - 383   2023

DOI PubMed CiNii Research

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Grant-in-Aid for Scientific Research 【 display / non-display 】

Grant-in-Aid for Scientific Research 【 display / non-display 】

• Grant-in-Aid for Scientific Research(C)

  Project Year： 2020.04  -  2022.03