Research Interests 【 display / non-display 】

Research Interests 【 display / non-display 】

display all >>

Graduating School 【 display / non-display 】

Graduating School 【 display / non-display 】

• 2000.04

  -

  2004.03

  Kyoto Pharmaceutical University   Faculty of Pharmaceutical Science   Graduated

Graduate School 【 display / non-display 】

Graduate School 【 display / non-display 】

• 2006.04

  -

  2010.03

  The University of Tokyo  Graduate School, Division of Medicine  Doctor's Course  Completed

Campus Career 【 display / non-display 】

Campus Career 【 display / non-display 】

• 2021.04

  -

  Now

  Akita University   Graduate School of Medicine   Doctorial Course in Medicine   Bioregulatory Medicine   Department of Immunology   Lecturer  

• 2010.07

  -

  2021.03

  Akita University   Graduate School of Medicine   Doctorial Course in Medicine   Bioregulatory Medicine   Assistant Professor  

External Career 【 display / non-display 】

External Career 【 display / non-display 】

• 2010.07

  -

  2021.03

  Akita Univ. Med.   Immunology   Assistant Professor  

Research Areas 【 display / non-display 】

Research Areas 【 display / non-display 】

• Life Science / Experimental pathology

• Life Science / Pathological biochemistry

• Life Science / Pathological biochemistry

• Life Science / Medical biochemistry

Qualification acquired 【 display / non-display 】

Qualification acquired 【 display / non-display 】

• Pharmacist

Thesis for a degree 【 display / non-display 】

Thesis for a degree 【 display / non-display 】

• ロイコトリエンB４第二受容体が有するHelix 8構造の 小胞体搬出における重要性についての研究

  Daisuke Yasuda 

  23   2010.03

  Single author

Research Achievements 【 display / non-display 】

Research Achievements 【 display / non-display 】

◆Original paper【 display / non-display 】

To the head of this page.▲

◆Original paper【 display / non-display 】

Lysophosphatidic acid-induced YAP/TAZ activation promotes developmental angiogenesis by repressing Notch ligand Dll4

Daisuke Yasuda, Daiki Kobayashi, Noriyuki Akahoshi, Takayo Ohto-Nakanishi, Kazuaki Yoshioka, Yoh Takuwa, Seiya Mizuno, Satoru Takahashi, and Satoshi Ishii

J. Clin. Invest.   ( 129 ) 4332 - 4349   2019.10  [Refereed]

Research paper (journal)   Domestic Co-author

The Gα12/13-coupled receptor, LPA4 limits proper adipose tissue expansion and remodeling in diet-induced obesity

Keisuke Yanagida, Hidemitsu Igarashi, Daisuke Yasuda, Daiki Kobayashi, Takayo Ohto-Nakanishi, Noriyuki Akahoshi, Atsushi Sekiba, Tsudoi Toyoda, Tomoko Ishijima, Yuji Nakai, Nobuhiro Shojima, Naoto Kubota, Keiko Abe, Takashi Kadowaki, Satoshi Ishii, and Takao Shimizu

JCI Insight   ( 3 ) e97293   2018.12  [Refereed]

Research paper (journal)   Domestic Co-author

Identification of optineurin as an interleukin-1 receptor-associated kinase 1-binding protein and its role in regulation of MyD88-dependent signaling

Mitsuyoshi Tanishima, Shigeo Takashima, Arata Honda, Daisuke Yasuda, Takashi Tanikawa, Satoshi Ishii, and Takashi MaruYama

J. Biol. Chem.   ( 292 ) 17250 - 17257   2017.10  [Refereed]

Research paper (journal)   Domestic Co-author

Lysophosphatidic acid receptor 4 activation augments drug delivery in tumors by tightening endothelial cell-cell contact

Kazuhiro Takara, Daisuke Eino, Koji Ando, Daisuke Yasuda, Hisamichi Naito, Yohei Tsukada, Tomohiro Iba, Taku Wakabayashi, Fumitaka Muramatsu, Hiroyasu Kidoya, Shigetomo Fukuhara, Naoki Mochizuki, Satoshi Ishii, Haruhiko Kishima, and Nobuyuki Takakura

Cell Rep.   20   2072 - 2086   2017.08  [Refereed]

Research paper (journal)   Domestic Co-author

The lysophosphatidic acid receptor LPA4 regulates hematopoiesis-supporting activity of bone marrow stromal cells

Hidemitsu Igarashi, Noriyuki Akahoshi, Takayo Ohto-Nakanishi, Daisuke Yasuda, and Satoshi Ishii

Sci. Rep.   5   11410   2015.06  [Refereed]

Research paper (journal)   Domestic Co-author

display all >>

To the head of this page.▲

◆Other【 display / non-display 】

To the head of this page.▲

◆Other【 display / non-display 】

Lysophosphatidic acid-induced YAP/TAZ activation promotes developmental angiogenesis by repressing Notch ligand Dll4.

Yasuda D, Kobayashi D, Akahoshi N, Ohto-Nakanishi T, Yoshioka K, Takuwa Y, Mizuno S, Takahashi S, Ishii S

The Journal of Clinical Investigation   129 ( 10 ) 4332 - 4349   2019.10

DOI PubMed

The Gα12/13-coupled receptor LPA4 limits proper adipose tissue expansion and remodeling in diet-induced obesity.

Yanagida K, Igarashi H, Yasuda D, Kobayashi D, Ohto-Nakanishi T, Akahoshi N, Sekiba A, Toyoda T, Ishijima T, Nakai Y, Shojima N, Kubota N, Abe K, Kadowaki T, Ishii S, Shimizu T

JCI insight   3 ( 24 )   2018.12

DOI PubMed

Grant-in-Aid for Scientific Research 【 display / non-display 】

Grant-in-Aid for Scientific Research 【 display / non-display 】

• Grant-in-Aid for Scientific Research(C)

  Project Year： 2022.04  -  2025.03 

• Grant-in-Aid for Scientific Research(C)

  Project Year： 2022.04  -  2025.03 

• Grant-in-Aid for Scientific Research(C)

  Project Year： 2019.04  -  Now 

• G12/13-dependent signaling of bioactive lipid receptors that regulate PPARgamma activity in adipocytes

  Grant-in-Aid for Scientific Research(B)

  Project Year： 2019.04  -  2022.03  Investigator(s): Ishii Satoshi

• Mechanisms of cancer progression control mediated by LPA-induced YAP activation

  Grant-in-Aid for Scientific Research(C)

  Project Year： 2019.04  -  2022.03  Investigator(s): Daisuke Yasuda

display all >>

Presentations 【 display / non-display 】

Presentations 【 display / non-display 】

• Gα12/13-coupled LPA receptors play an important role in developmental angiogenesis

  Daisuke Yasuda, Daiki Kobayashi, Kazuaki Yoshioka, Yoh Takuwa, Satoshi Ishii

  ICBL 2019 -60th International Conference on the Bioscience of Lipids-  2019.06  -  2019.06 

• Gα12/13-coupled LPA receptors mediate novel angiogenesis mechanism

  Daisuke Yasuda, Satoshi Ishii

  FASEB Summer Research Conferences; Lysophospholipid and Related Mediators: From Bench to Clinic  2017.08  -  2017.08