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Affiliation |
Graduate School of Medicine Doctorial Course in Medicine Organ Function-Oriented Medicine Department of Obstetrics and Gynecology |
KUMAZAWA Yukiyo
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Graduating School 【 display / non-display 】
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-2005.03
Akita University Faculty of Medicine Graduated
Graduate School 【 display / non-display 】
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-2005.03
Akita University Graduate School,Division of Medicine Doctor's Course Completed
Campus Career 【 display / non-display 】
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2024.04-Now
Akita University Graduate School of Medicine Doctorial Course in Medicine Organ Function-Oriented Medicine Department of Obstetrics and Gynecology Associate Professor
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2020.08-2024.03
Akita University Hospital Deliverry Center Associate Professor
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2016.11-2020.07
Akita University Hospital Obstetrics and Gynecology Lecturer
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2009.04-2016.10
Akita University School of Medicine Assistant Professor
Thesis for a degree 【 display / non-display 】
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Human chorionic gonadotropin up-regulates survivin mRNA in human granulosa sells
Yukiyo Kumazawa1,3, Kazuhiro Kawamura1, Toshiharu Sato1, Naoki Sato1, Yoshitomo Konishi1, Yosushi Shimizu1, Jun Fukuda1, Hideya Kodoma2 and Toshinobu Tanaka1
2005.03
Domestic Co-author
Research Achievements 【 display / non-display 】
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Cervical varix with placenta previa totalis.
Kumazawa Y1, Shimizu D, Hosoya N, Hirano H, Ishiyama K, Tanaka T.
J Obstet Gynaecol Res. 2007.08 [Refereed]
Research paper (journal) Domestic Co-author
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HCG up-regulates survivin mRNA in human granulosa cells.
Kumazawa Y1, Kawamura K, Sato T, Sato N, Konishi Y, Shimizu Y, Fukuda J, Kodama H, Tanaka T.
Mol Hum Reprod 2005.03 [Refereed]
Research paper (journal) Domestic Co-author
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The timing of the release of the first polar body predicts the cleavage rate after parthenogenetic activation for human oocytes obtained by in vitro maturation
Hiromitsu Shirasawa, Yukiyo KUMAZAWA, Wataru SATO, Kazumasa TAKAHASHI, Yukihiro TERADA
Fertility and Sterility 112 ( 3 ) e142 - e142 2019.09 [Refereed]
Research paper (international conference proceedings)
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Shape of the first mitotic spindles impacts multinucleation in human embryos
Ono Yuki, Shirasawa Hiromitsu, Takahashi Kazumasa, Goto Mayumi, Ono Takahiro, Sakaguchi Taichi, Okabe Motonari, Hirakawa Takeo, Iwasawa Takuya, Fujishima Akiko, Sugawara Tae, Makino Kenichi, Miura Hiroshi, Fukunaga Noritaka, Asada Yoshimasa, Kumazawa Yukiyo, Terada Yukihiro
Akita journal of medicine 52 ( 2 ) 21 - 24 2025.08
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Semen essential and toxic elements in relation to semen quality in Japanese men
IWAI-SHIMADA Miyuki, IWAI Kenta, TATSUTA Nozomi, ISOBE Tomohiko, TAKAGI Mai, KOBAYASHI Yayoi, NAKAYAMA Shoji F., KUMAZAWA Yukiyo, TAKAHASHI Kazumasa, TANAKA Takashi, TERADA Yukihiro, NOMURA Kyoko, OKADA Hiroshi, TAMAKOSHI Akiko, MAEDA Eri
Annual Meeting of the Japanese Society of Toxicology ( The Japanese Society of Toxicology ) 52.1 ( 0 ) O-43 2025
<p>WHO recommends health promotion before conception (preconception care). Male preconception care is important for family planning and infertility management. Essential elements play an important role in sperm maturation and motility, and it has been reported that essential elements are associated with male fertility, but studies on Japanese men are limited. Therefore, the aim of this study was to evaluate the relationship between 17 essential and toxic elements in semen and sperm quality. Healthy adult men aged 20-39 years were asked to collect semen samples using sterile plastic containers after 2-5 days of abstinence and to submit them to a hospital within 2 hours of collection, where sperm quality was evaluated (N=372). 17 elements (magnesium (Mg), manganese (Mn), calcium (Ca), iron (Fe), cobalt (Co), copper (Cu), zinc (Zn), selenium (Se), molybdenum (Mo), iodine (I), mercury (Hg), lead (Pb), cadmium (Cd), thallium (TI), nickel (Ni), silver (Ag), and tungsten (W)) concentrations were determined by inductively coupled plasma mass spectrometry (ICP-MS). The k-means cluster analysis was used to classify into three clusters. In the cluster corresponding to 14% of the participants, parameters related to sperm quality (number of motile sperm and motility rate) were higher, and concentrations of essential elements (Mg, Mn, Fe, Co, Cu, Zn, Se, and Mo) were higher. Further detailed investigation is needed.</p>
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Iwasawa Takuya, Sakaguchi Taichi, Shirasawa Hiromitsu, Kumazawa Yukiyo, Terada Yukihiro
JAPANESE JOURNAL OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY ( JAPAN SOCIETY OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY AND MINIMALLY INVASIVE THERAPY ) 40 ( 1 ) 100 - 104 2024
<p> An intrauterine device (IUD) is a commonly used, reversible contraception. Reports of IUD-related complications have increased, and one of these is uterine perforation at IUD insertion with subsequent migration into the intraperitoneal cavity. This is a rare complication, occurring in approximately 0.2-3.6 per 1000 cases. We report a case of laparoscopic surgery for removal of an IUD that had migrated into the uterine myometrium. A 39-year-old nulliparous woman underwent IUD insertion to prevent intrauterine adhesions after laparoscopic myomectomy (LM). Three months after LM, the IUD could not be removed by pulling the IUD strings. CT and MRI revealed that the IUD had migrated into the uterine myometrium. We removed the IUD by laparoscopic surgery. Insertion of an IUD after myomectomy, especially under anesthesia, carries a risk of uterine perforation. Multiple cross-sectional images on CT and MRI are useful for diagnosing IUD migration into the uterine myometrium.</p>
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Pseudo-Meigs' Syndrome in a Patient With Uterine Fibroids With Massive Pleural Effusion After Starting Gonadotropin-Releasing Hormone Agonist Therapy: A Case Report.
Hidesato Odaka, Ruriko Asahi, Kengo Shimada, Takuo Tokairin, Yukiyo Kumazawa
Cureus 15 ( 1 ) e33520 2023.01
Pseudo-Meigs' syndrome is caused by uterine fibroids, which is often treated using gonadotropin-releasing hormone (GnRH) agonists. Here we report a case of pseudo-Meigs' syndrome that developed with massive pleural effusion after the initiation of GnRH agonist therapy for uterine fibroids. A 48-year-old woman presented with dyspnea. Her medical history included uterine fibroids and GnRH agonist therapy. Contrast-enhanced computed tomography revealed a massive pleural effusion, uterine fibroids, and ascites. A total laparoscopic hysterectomy was performed. The pathologic findings were consistent with those of uterine fibroids. The pleural effusion and ascites resolved completely. The patient was diagnosed with pseudo-Meigs' syndrome due to uterine fibroids.
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Togashi Kazue, Kumazawa Yukiyo, Shirasawa Hiromitsu, Kukimoto Shioka, Ono Natsuki, Sato Wataru, Shimizu Dai, Terada Yukihiro
JAPANESE JOURNAL OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY ( JAPAN SOCIETY OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY AND MINIMALLY INVASIVE THERAPY ) 36 ( 2 ) 341 - 347 2020
<p><b>Introduction:</b> Ovarian auto-amputation is extremely rare and is most commonly attributed to chronic adnexal torsion and subsequent devascularization that precipitate infarction and necrosis. We describe a woman (Jehovah's witness) who presented with an inflamed abdominal cyst, which was diagnosed as an auto-amputated endometrial ovarian cyst, following laparoscopic surgery.</p><p><b>Case presentation:</b> A 45-year-old Jehovah's witness was referred to our hospital with acute abdominal pain. She had complained of dysmenorrhea prior to referral. Laboratory data revealed evidence of severe inflammation (white blood cell count 12400 cells/μL, C-reactive protein 17.4 mg/dL).</p><p> MRI revealed a cystic pelvic tumor with features of a benign ovarian cyst. She received intravenous antibiotics with resolution of inflammation following this conservative therapy after which we performed laparoscopic surgery for removal of the pelvic mass. Intraoperatively, we performed careful adhesiolysis followed by meticulous exploration of the pelvic cavity. We performed cystectomy and left adnexectomy with insertion of multiple drains into the peritoneal cavity.</p><p><b>Discussion:</b> Based on the laparoscopic and histopathological findings, the patient was diagnosed with chemical panperitonitis associated with a wandering ovarian endometrial cyst.</p><p><b>Conclusion:</b> We report successful but significantly challenging laparoscopic intervention for a wandering ovarian endometrial cyst in a woman with chemical peritonitis.</p><p></p>
◆Original paper【 display / non-display 】
◆International conference proceedings【 display / non-display 】
◆Other【 display / non-display 】
Grant-in-Aid for Scientific Research 【 display / non-display 】
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Cellar and Biological Study of Human Embryonal Development for the Improvement of Assisted Reproductive Technology
Grant-in-Aid for Scientific Research(A)
Project Year： 2025.04 - 2029.03
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Grant-in-Aid for Scientific Research(C)
Project Year： 2024.04 - 2027.03
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Grant-in-Aid for Scientific Research(C)
Project Year： 2022.04 - 2025.03
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Grant-in-Aid for Scientific Research(C)
Project Year： 2021.04 - 2024.03
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Grant-in-Aid for Scientific Research(C)
Project Year： 2019.04 - 2023.03