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Affiliation |
Graduate School of Medicine Doctorial Course in Medicine Bioregulatory Medicine Department of General Medical Practice and Laboratory Diagnostic Medicine |
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Laboratory Phone number |
+8118846209 |
UEKI Shigeharu
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Research Interests 【 display / non-display 】
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Infection control
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laboratory medicine
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アレルギー
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内科
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呼吸器学
Graduating School 【 display / non-display 】
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-1999.03
Akita University Faculty of Medicine Graduated
Graduate School 【 display / non-display 】
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-2003.03
Akita University Graduate School,Division of Medicine Doctor's Course Completed
Campus Career 【 display / non-display 】
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2021.10-Now
Akita University Graduate School of Medicine Doctorial Course in Medicine Bioregulatory Medicine Department of General Medical Practice and Laboratory Diagnostic Medicine Professor
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2014.04-2021.09
Akita University Graduate School of Medicine Doctorial Course in Medicine Bioregulatory Medicine Department of General Medical Practice and Laboratory Diagnostic Medicine Associate Professor
Research Areas 【 display / non-display 】
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Life Science / Connective tissue disease and allergy
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Life Science / Respiratory medicine
Research Achievements 【 display / non-display 】
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Allergic fungal diseases in the upper and lower airways
Ueki S.
ERS Monograph ( ERS Monograph ) 2022 119 - 140 2022 [Refereed] [Invited]
Research paper (journal) Domestic Co-author
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Hypogranular eosinophils in eosinophilic gastrointestinal disease
Tomizawa H.
International Journal of Laboratory Hematology ( International Journal of Laboratory Hematology ) 2022 [Refereed]
Research paper (journal) Domestic Co-author
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Comparison of CD16-negative selection vs. MACSxpress system for isolation of blood eosinophils
Fukuchi Mineyo, Ueki Shigeharu, Saito Hidekazu, Miyabe Yui, Konno Yasunori, Omokawa Ayumi, Saga Tomoo, Moritoki Yuki, Takeda Masahide, Yamada Takechiyo, Hirokawa Makoto
Allergology International ( 一般社団法人日本アレルギー学会 ) 68 ( Supplement.1 ) S11 - S13 2019 [Refereed]
Research paper (journal) Domestic Co-author
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Eosinophil extracellular trap cell death-derived DNA traps: Their presence in secretions and functional attributes.
Ueki S, Konno Y, Takeda M, Moritoki Y, Hirokawa M, Matsuwaki Y, Honda K, Ohta N, Yamamoto S, Takagi Y, Wada A, Weller PF
The Journal of allergy and clinical immunology 2015.06 [Refereed]
Research paper (journal) Domestic Co-author
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Konno Y, Ueki S, Takeda M, Kobayashi Y, Tamaki M, Moritoki Y, Oyamada H, Itoga M, Kayaba H, Omokawa A, Hirokawa M.
Konno Y, Ueki S, Takeda M, Kobayashi Y, Tamaki M, Moritoki Y, Oyamada H, Itoga M, Kayaba H, Omokawa A, Hirokawa M.
PLoS One. 10 ( 3 ) e0120386. 2015.03 [Refereed]
Research paper (journal) Domestic Co-author
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Endovascular Retrieval of a Fractured Tunneled Hemodialysis Central Venous Catheter Using the Loop Snare Technique.
Tomoko Sasaki, Yuki Fujioka, Haruka Hikichi, Daisuke Yokota, Shigeharu Ueki
Cureus 15 ( 2 ) e35617 2023.02
The tunneled cuffed hemodialysis catheter is a valuable vascular access option for patients with end-stage renal disease (ESRD). Healthcare providers have become more familiar with the insertion of medical devices, including central venous catheters, in their daily practice. The occurrence of foreign body fragmentation is rare with these catheters. This article presents a case in which a fracture of the distal portion of the hemodialysis catheter was inadvertently identified during a coronary angiography. Percutaneous removal of the fractured venous catheter was performed successfully using a loop snare catheter, which prevented the patient from experiencing further complications.
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Diagnostic Challenges in Pulmonary Embolism in Young Adults: Thrombosis Associated With Cytomegalovirus and Mycoplasma pneumoniae.
Haruka Hikichi, Ryo Hasegawa, Akiko Saga, Tomoo Saga, Shigeharu Ueki
Cureus 14 ( 12 ) e32757 2022.12
A 23-year-old man presented with a fever, shaking chills, headaches, nausea, and a dry cough. Investigations showed lymphocytic leukocytosis with atypical lymphocytes in a blood smear. Liver function test results, D-dimer concentrations, and fibrin degradation product concentrations were greatly elevated. Computed tomography of the whole body with contrast showed hepatosplenomegaly with splenic infarction and bilateral pulmonary embolism without deep vein thrombosis. Cytomegalovirus (CMV) immunoglobulin M, and serum CMV pp65 antigenemia were positive, and serum Mycoplasma pneumoniae (M. pneumoniae) antibody was also highly positive. These results suggested the diagnosis of co-infection of CMV and M. pneumoniae complicated by systemic arteriovenous thrombosis, which resulted in pulmonary embolism and splenic infarction. After he started edoxaban tosilate hydrate for the thrombosis, his symptoms resolved in a few days. To the best of our knowledge, this is the first case of co-infection of CMV and M. pneumoniae leading to pulmonary embolism and splenic infarction.
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Irie Yasuhito, Nakae Hajime, Saga Akiko, Hikichi Haruka, Watanabe Ken, Satoh Kasumi, Kitamura Toshiharu, Ueki Shigeharu
JOURNAL OF HOSPITAL GENERAL MEDICINE ( 一般社団法人 日本病院総合診療医学会 ) 4 ( 3 ) 148 - 152 2022.05
[Case] A 28-year-old man presented with fatigue, headache, bilateral shoulder pain, chills, and diarrhea. Although he was healthy, his symptoms appeared on the day after vaccination with his second dose of the Pfizer-BioNTech vaccine. He visited our outpatient clinic for Kampo medicine treatment on day 10. Based on the clinical course, the patient was considered to have vaccine- induced side effects, and keishito was prescribed according to the Eastern medicine findings. On day 13, his sweating disappeared, and headache and chills showed improvement;however, shoulder pain and fatigue persisted. On day 27, purple spots on the tongue were considered blood stasis, so the patient was prescribed tsudosan, which improved his shoulder pain. On day 52, the numeric rating scale score was 1 point, indicating a trend toward improvement. [Discussion] Side effects are typically common following vaccination as the body is building immunity to antigens;however, they usually subside within a few days. Western medicine alone cannot maintain the quality of life of patients experiencing prolonged symptoms. [Conclusions] Kampo medicine can be used to develop complementary medical treatments, even in clinical areas where evidence is yet to be accumulated.
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Irie Yasuhito, Nakae Hajime, Saga Akiko, Hikichi Haruka, Watanabe Ken, Satoh Kasumi, Kitamura Toshiharu, Ueki Shigeharu
Journal of Hospital General Medicine ( (一社)日本病院総合診療医学会 ) 4 ( 3 ) 148 - 152 2022.05
症例は28歳男性で、COVID-19ワクチン(Pfizer-BioNTech)2回目接種の翌日から、倦怠感、頭痛、両肩痛、悪寒、下痢を呈していた。4日目に両肩痛に対して鍼治療が行われていた。6日目には近医にてNSAIDsおよび補中益気湯が処方されていた。しかし、症状の改善は認められず、9日目に救急外来を受診した。しかし、異常所見は認められず、10日目に当院漢方外来を受診した。臨床経過からワクチンによる副作用と判断し、東洋医学的知見に基づき桂枝湯が処方された。13日目に発汗の消失および頭痛、悪寒の改善が認められたが、肩こり、倦怠感は持続した。舌の紫斑はお血である考え、27日目に通導散を処方した。その結果、肩痛が改善された。52日目には初診時満点であったNumeric Rating Scaleが1点に改善された。
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[CURRENT RESEARCH TRENDS IN EXTRACELLULAR TRAPS (NETs AND EETs)].
Ken Watanabe, Shigeharu Ueki
Arerugi = [Allergy] ( Japanese Society of Allergology ) 71 ( 3 ) 199 - 205 2022
◆Original paper【 display / non-display 】
◆Other【 display / non-display 】
Grant-in-Aid for Scientific Research 【 display / non-display 】
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Virus specific host responses and induction of etosis in severe influenza
Grant-in-Aid for Scientific Research(C)
Project Year： 2022.04 - 2025.03
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Understanding of the pathophysiology of gastrointestinal allergies and related diseases using microfiber cell isolation
Grant-in-Aid for Scientific Research(C)
Project Year： 2021.04 - 2024.03
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Understanding of the pathophysiology of gastrointestinal allergies and related diseases using microfiber cell isolation
Grant-in-Aid for Scientific Research(C)
Project Year： 2021.04 - 2024.03
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Grant-in-Aid for Scientific Research(C)
Project Year： 2021.04 - 2024.03
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Understanding of the pathophysiology of gastrointestinal allergies and related diseases using microfiber cell isolation
Grant-in-Aid for Scientific Research(C)
Project Year： 2021.04 - 2024.03