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Affiliation |
Graduate School of Medicine Doctorial Course in Medicine Public Health and Environmental Medicine Department of Forensic Science |
HAYAKAWA Akira
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Research Interests 【 display / non-display 】
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Forensic Pathology
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Postmortem Imaging
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心臓性突然死
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死後画像検査
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死後血液生化学検査
Graduating School 【 display / non-display 】
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-2012.03
Hokkaido University Faculty of Medicine Graduated
Graduate School 【 display / non-display 】
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-2015.03
Hokkaido University Graduate School,Division of Medicine Doctor's Course Completed
Campus Career 【 display / non-display 】
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2024.03-Now
Akita University Graduate School of Medicine Doctorial Course in Medicine Public Health and Environmental Medicine Department of Forensic Science Professor
External Career 【 display / non-display 】
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2024.03
Akita University Department of Forensic Sciences Professor
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2022.12-2024.02
Gunma University Graduate School of Medicine Department of Legal Medicine Senior Lecturer
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2021.10-2022.09
Karolinska Institutet Department of Oncology-Pahology Postdoctoral Researcher
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2020.04-2022.11
Gunma University Graduate School of Medicine Department of Legal Medicine
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2018.04
Tokyo Medical Examiner's Office Medical Examiner (Part-time)
Research Areas 【 display / non-display 】
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Life Science / Molecular biology
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Life Science / Forensics medicine
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Life Science / Human pathology
Research Achievements 【 display / non-display 】
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CT-based assessment of bear-inflicted maxillofacial injuries: evaluation using the facial injury severity scale and its association with hospitalization duration.
Kento Hatakeyama, Takahiro Otani, Kasumi Satoh, Hideomi Tsuchida, Tomoki Tozawa, Motoko Konno, Shinsuke Suzuki, Takafumi Tezuka, Shunji Mugikura, Akira Hayakawa, Takechiyo Yamada, Hajime Nakae, Naoko Mori
Japanese journal of radiology 43 ( 11 ) 1812 - 1821 2025.11
Research paper (journal)
PURPOSE: Bear-inflicted injuries are often associated with severe maxillofacial injury. This study aimed to evaluate CT findings of bear-inflicted injuries using the Facial Injury Severity Scale (FISS) and other trauma grading systems, with a particular focus on the relationship between FISS scores and hospitalization duration as well as the characteristics of maxillofacial injuries. MATERIALS AND METHODS: This retrospective study included 31 patients with bear-inflicted injuries who underwent whole-body CT. Maxillofacial injury severity was assessed using FISS, while head and thoracic injuries were evaluated using the Marshall Head-CT Classification and the AAST Chest Wall Injury Scale, respectively. Patients were categorized into short (≤ 18 days) and long (> 18 days) hospitalization groups based on the median hospitalization duration. Univariate and multivariate analyses were performed to identify factors associated with hospitalization duration. RESULTS: Patients in the long hospitalization group had higher FISS scores (p = 0.01) and AAST chest wall injury grades (p = 0.03), with no significant differences in Marshall Head-CT Classification. Multivariate analysis confirmed that both FISS scores and AAST chest wall injury grade were independently associated with hospitalization duration. A detailed analysis of FISS scores revealed significant bilateral correlations between right and left midface scores (p < 0.01) and right and left upper face scores (p < 0.01). Additionally, significant correlations were observed between midface and upper face scores. CONCLUSION: FISS scores and AAST chest wall injury grades were significantly associated with hospitalization duration in bear-inflicted injuries. The midface and upper face injuries often occur simultaneously and bilaterally, possibly due to bears targeting the upper face to weaken their opponent.
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Colchicine destroys the intestinal barrier function and induces endotoxin shock
Hiroki Tanaka, Kie Horioka, Akira Hayakawa, Shotaro Isozaki, Seiji Ohtani, Katsuhiro Okuda, Masaru Asari, Katsuhiro Ogawa, Hiroshi Shiono, Keiko Shimizu
Forensic Science International 277 162 - 162 2017.08 [Refereed]
Research paper (journal)
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Virtual reassembly of the skull and spine in fragmentation due to trauma or postmortem changes
福田治紀, 早川輝, 高橋遥一郎, 佐野利恵, 窪理英子, 徳江浩之, 小湊慶彦
日本法医学会学術全国集会講演要旨集 107th 2023
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DECREASED EXPRESSION OF BOTH A AND B BLOOD ANTIGENS IN A PATIENT WITH MYELODYSPLASTIC SYNDROME
Ishikawa Reina, Maruhashi Takayuki, Susa Kozue, Nishimoto Natsumi, Iwahara Kanae, Goto Hideki, Ishikawa Osamu, Hayakawa Akira, Takahashi Yoichiro, Sano Rie, Kominato Yoshihiko, Yokohama Akihiko
Japanese Journal of Transfusion and Cell Therapy ( The Japan Society of Transfusion Medicine and Cell Therapy ) 68 ( 3 ) 428 - 434 2022.06
<p>A man in his 20s was diagnosed with pyoderma gangrenosum and underwent emergency debridement. He had no history of a hematological disease, transfusion, or hematopoietic stem cell transplantation. ABO blood group typing results showed mixed field agglutination with both A and B blood antigens. Due to the possible association between hematological disease and pyoderma gangrenosum, bone marrow aspiration was performed and he was diagnosed with myelodysplastic syndrome with multilineage dysplasia (MDS-MLD) with chromosome 8 trisomy.</p><p>Serological tests, flow cytometric analysis, and genetic test precluded the possibility of hereditary ABO subgroup and blood chimerism, suggesting that his blood antigen expression was decreased due to MDS-MLD.</p><p>In turn, decreased A and B antigen expression and diagnosis of pyoderma gangrenosum allowed the diagnosis of MDS-MLD before he had overt abnormal hematological values.</p><p>For patients with decreased expression of both A and B blood antigens, the possibility of hematological disease should be kept in mind.</p>
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骨髄異形成症候群の一患者におけるABO式血液型抗原量低下の原因解明
早川輝, 佐野利恵, 高橋遥一郎, 小湊慶彦, 半田寛, 丸橋隆行, 横濱章彦
北関東医学会総会プログラム・抄録 69 ( 3 ) 302 - 302 2019.08
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骨髄異形成症候群の一患者におけるABO式血液型抗原量低下の原因解明
早川輝, 佐野利恵, 高橋遥一郎, 窪理英子, 小湊慶彦
日本法医学雑誌 73 ( 1 ) 76 - 76 2019.05
◆Original paper【 display / non-display 】
◆Other【 display / non-display 】
Grant-in-Aid for Scientific Research 【 display / non-display 】
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Grant-in-Aid for Scientific Research(C)
Project Year： 2025.04 - 2028.03
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Development of a new diagnostic method for acute myocardial ischemia and search for diagnostic biomarkers
Grant-in-Aid for Scientific Research(C)
Project Year： 2025.04 - 2028.03
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Myocardial protection mechanisms in hypothermia from myocardial cell energy metabolism changes.
Grant-in-Aid for Scientific Research(C)
Project Year： 2025.04 - 2028.03
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Grant-in-Aid for Scientific Research(C)
Project Year： 2023.04 - 2026.03
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Grant-in-Aid for Scientific Research(C)
Project Year： 2023.04 - 2026.03
Presentations 【 display / non-display 】
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Elucidation of the underlying mechanism responsible for blood group ABO antigen reduction on erythrocytes in patients with myelodysplastic syndrome
Akira Hayakawa, Rie Sano, Yoichiro Takahashi, Takafumi Okawa, Rieko Kubo, Megumi Harada, Haruki Fukuda, Akihiko Yokohama, Hiroshi Handa, Reika Kawabata‐Iwakawa, Hatsue Tsuneyama, Junichi Tsukada, Yoshihiko Kominato
The 37th International congress of the International Society of Blood Transfusion (ISBT2022) 2022.06 - 2022.06
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Rewarming from accidental hypothermia enhances whole blood clotting properties in a murine model
Kie Horioka, Hiroki Tanaka, Shotaro Isozaki, Akira Hayakawa, Shuhei Takauji, Henrik Druid
The 21st Nordic Conference on Forensic Medicine (NCFM) and the 6th Annual Meeting of the Nordic Association of Forensic Toxicologists (NAFT) 2022.05 - 2022.05
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Death Investigation System in Japan.
Akira Hayakawa [Invited]
Rättsmedicinalverket (The National Board of Forensic Medicine) Stockholm 2022.05 - 2022.05
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Heat stress induces fatty liver in a mouse model of heat stroke
Hiroki Tanaka, Takahiro Deguchi, Kie Horioka, Akira Hayakawa, Shuhei Takauji, Shotaro Isozaki, Henrik Druid
The 21st Nordic Conference on Forensic Medicine (NCFM) and the 6th Annual Meeting of the Nordic Association of Forensic Toxicologists (NAFT) 2022.05 - 2022.05
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Molecular pathological elucidation of frostbite using mouse model
Shotaro Isozaki, Hiroki Tanaka, Kie Horioka, Hiroaki Konishi, Akira Hayakawa, Shin Kashima, Henrik Druid
The 21st Nordic Conference on Forensic Medicine (NCFM) and the 6th Annual Meeting of the Nordic Association of Forensic Toxicologists (NAFT) 2022.05 - 2022.05
Academic Activity 【 display / non-display 】
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2025.07-Now
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2025.07-Now
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2025.07-Now
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2025.04-Now
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2024.10-Now