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Affiliation |
Graduate School of Medicine Doctorial Course in Medicine Oncoregulatory Medicine Department of Thoracis Surgery |
KURIYAMA Shoji
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Graduating School 【 display / non-display 】
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-2013.03
Akita University Faculty of Medicine Graduated
Graduate School 【 display / non-display 】
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-2022.09
Akita University Graduate School, Division of Medicine Doctor's Course Completed
Campus Career 【 display / non-display 】
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2023.07-Now
Akita University Graduate School of Medicine Doctorial Course in Medicine Oncoregulatory Medicine Department of Thoracis Surgery Assistant Professor
Thesis for a degree 【 display / non-display 】
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Using CT to evaluate mediastinal great vein invasion by thymic epithelial tumors: measurement of the interface between the tumor and neighboring structures
Shoji Kuriyama, Kazuhiro Imai, Koichi Ishiyama, Shinogu Takashima, Maiko Atari, Tsubasa Matsuo, Yoshiaki Ishii, Yuzu Harata, Yusuke Sato, Satoru Motoyama, Kyoko Nomura, Manabu Hashimoto, Yoshihiro Minamiya
European Radiology 2022.09 [Refereed]
Single author
Research Achievements 【 display / non-display 】
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Prognostic impact of preoperative osteopenia in elderly patients with lung cancer.
Shoji Kuriyama, Motoko Konno, Naoko Mori, Shinogu Takashima, Tsubasa Matsuo, Hidenobu Iwai, Haruka Suzuki, Tatsuki Fujibayashi, Sumire Shibano, Akiyuki Wakita, Yusuke Sato, Kyoko Nomura, Yoshihiro Minamiya, Kazuhiro Imai
World journal of surgical oncology 2025.12
Research paper (journal)
BACKGROUND: Osteopenia was recently reported to be a factor contributing to a poorer prognosis in various cancers. However, its prognostic impact on non-small cell lung cancer (NSCLC) patients remains unclear. In the present study, we focused on osteopenia in elderly NSCLC patients and investigated survival outcomes. METHODS: This study included 315 NSCLC patients aged 75 years or older who had undergone radical lobectomy or segmentectomy at our institution between 2010 and 2023. Osteopenia was evaluated based on the average pixel density within a circle in the mid-vertebral core at the 11th thoracic vertebra on preoperative computed tomography. RESULTS: Osteopenia was identified in 126 patients (40%). This osteopenia group had significantly poorer overall survival (OS) than the non-osteopenia group (5-year OS: 71.4%vs 81.0%, p = 0.026). Multivariable analysis revealed that Charlson comorbidity index (CCI) ≥ 2 (p = 0.020), Brinkman index (BI) ≥ 400 (p < 0.001), pathological Stage ≥ II (p < 0.001), and osteopenia (p = 0.016) were independent factors affecting OS. The cumulative incidence of non-lung cancer mortality was significantly higher in the osteopenia group than non-osteopenia group (5-year mortality rate: 16.9% vs. 6.4%, p = 0.005). In multivariable analysis, CCI ≥ 2 (p = 0.009), BI ≥ 400 (p < 0.008) and osteopenia (p = 0.001) were independent factors affecting non-lung cancer mortality. CONCLUSIONS: Elderly patients with osteopenia have significantly poorer OS, and osteopenia was closely associated with non-lung cancer mortality. Screening for osteopenia may assist in identifying high-risk patients of non-lung cancer death and developing appropriate treatment strategies.
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Multiple Pulmonary Cavernous Hemangioma: A Case Report
Takashima Shinogu, Nanjo Hiroshi, Matsuo Tsubasa, Kuriyama Shoji, Iwai Hidenobu, Suzuki Haruka, Kobayashi Mirai, Fujibayashi Tatsuki, Shibano Sumire, Minamiya Yoshihiro, Imai Kazuhiro
Surgical Case Reports ( 一般社団法人 日本外科学会 ) 11 ( 1 ) n/a 2025
Research paper (journal)
<p><b>INTRODUCTION:</b> Pulmonary cavernous hemangioma (PCH) is extremely rare and, due to the lack of specific radiological characteristics, is often misdiagnosed as other pulmonary diseases, including metastatic tumors. Here, we report a case of multiple PCH lesions with concomitant hepatic cavernous hemangioma (HCH), emphasizing the diagnostic implications of imaging findings.</p><p><b>CASE PRESENTATION:</b> A 57-year-old man presented with fever. CT revealed numerous well-circumscribed pulmonary nodules and multiple low-density hepatic lesions. Dynamic contrast-enhanced CT demonstrated mild, nonspecific enhancement of the pulmonary nodules, whereas the hepatic lesions showed enhancement from the center to the periphery. Serum tumor markers were within normal limits, and PET-CT revealed no abnormal fluorodeoxyglucose uptake in any of the lesions. Although the hepatic lesions appeared suggestive of hemangioma on imaging, the possibility of malignancy, such as hepatic angiosarcoma and its pulmonary metastases, could not be completely ruled out. Therefore, both hepatic and pulmonary biopsies were performed, and histopathological examination confirmed cavernous hemangioma in both organs.</p><p><b>CONCLUSIONS:</b> PCH is a rare benign tumor lacking distinctive imaging characteristics; therefore, differentiation from metastatic pulmonary tumors is often challenging and represents a key diagnostic issue. Although definitive diagnosis currently relies on surgical biopsy, combining suggestive imaging findings—such as the presence of microcalcifications within nodules and the absence of fluorodeoxyglucose uptake on PET-CT—may help avoid unnecessary invasive procedures.</p>
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A case of right middle lobectomy for primary lung cancer in a patient with heterotaxy syndrome.
Ryo Demura, Kazuhiro Imai, Shinogu Takashima, Nobuyasu Kurihara, Shoji Kuriyama, Haruka Suzuki, Yuzu Harata, Yoshihiro Minamiya
General Thoracic and Cardiovascular Surgery Cases ( General Thoracic and Cardiovascular Surgery Cases ) 3 ( 1 ) 52 - 52 2024.11
Research paper (journal)
BACKGROUND: Anatomical abnormalities in the pulmonary vessels have long aroused great interest among thoracic surgeons, and numerous variations of pulmonary vessels have been reported. Heterotaxy syndrome is an anatomical abnormality in which typically asymmetrical organs, including the lungs, develop symmetrically. We report the case of a 71-year-old man with heterotaxy syndrome undergoing radical lobectomy in the treatment of non-small cell lung cancer. CASE PRESENTATION: Computed tomography (CT) revealed an irregular nodule 25 mm in diameter in the right middle lobe. Two months later, at his first visit to our University Hospital, CT revealed a rapidly growing tumor 60 mm in diameter. In addition, three-dimensional (3D) CT revealed the upper and middle lobar bronchi forming a common trunk with the mediastinal type of the right pulmonary artery (PA). The patient underwent video-assisted right middle lobectomy + systematic complete hilar and mediastinal lymph node dissection. The interlobar fissure between the right upper and middle lobes was incomplete, and the common trunk formed by the upper-middle bronchus emerged from an area between the right PA (A1+3) and the right superior pulmonary vein. CONCLUSION: The finding of A4+5 branching from the right main PA and descending posterior to the right upper-middle bronchus, which formed a common trunk, resembled a mirror image of the normal left lung. To our knowledge, a common trunk with the mediastinal type of the right PA has never been reported during video-assisted right middle lobectomy. In patients with heterotaxy syndrome, 3D-CT to preoperatively understand their anatomy is essential.
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Tracheal bifurcation repair for blunt thoracic trauma in a patient with COVID-19.
Shoji Kuriyama, Kazuhiro Imai, Kasumi Tozawa, Shinogu Takashima, Ryo Demura, Haruka Suzuki, Yuzu Harata, Tatsuki Fujibayashi, Sumire Shibano, Yoshihiro Minamiya
Surgical case reports 9 ( 1 ) 108 - 108 2023.06
Research paper (journal)
BACKGROUND: Tracheobronchial injury (TBI) is a rare but potentially life-threatening trauma that requires prompt diagnosis and treatment. We present a case in which a patient with COVID-19 infection was successfully treated for a TBI through surgical repair and intensive care with extracorporeal membrane oxygenation (ECMO) support. CASE PRESENTATION: This is the case of a 31-year-old man transported to a peripheral hospital following a car crash. Tracheal intubation was performed for severe hypoxia and subcutaneous emphysema. Chest computed tomography showed bilateral lung contusion, hemopneumothorax, and penetration of the endotracheal tube beyond the tracheal bifurcation. A TBI was suspected; moreover, his COVID-19 polymerase chain reaction screening test was positive. Requiring emergency surgery, the patient was transferred to a private negative pressure room in our intensive care unit. Due to persistent hypoxia and in preparation for repair, the patient was started on veno-venous ECMO. With ECMO support, tracheobronchial injury repair was performed without intraoperative ventilation. In accordance with the surgery manual for COVID-19 patients in our hospital, all medical staff who treated this patient used personal protective equipment. Partial transection of the tracheal bifurcation membranous wall was detected and repaired using 4-0 monofilament absorbable sutures. The patient was discharged on the 29th postoperative day without postoperative complications. CONCLUSIONS: ECMO support for traumatic TBI in this patient with COVID-19 reduced mortality risk while preventing aerosol exposure to the virus.
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Inferior pulmonary ligament division during left upper lobectomy causes pulmonary dysfunction
Shoji Kuriyama, Kazuhiro Imai, Hajime Saito, Shinogu Takashima, Nobuyasu Kurihara, Ryo Demura, Haruka Suzuki, Yuzu Harata, Yusuke Sato, Katsutoshi Nakayama, Kyoko Nomura, Yoshihiro Minamiya
Interdisciplinary cardiovascular and thoracic surgery 2023.05 [Refereed]
Research paper (journal) Single author
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Extracorporeal Membrane Oxygenation-Assisted Thoracic Surgery: A Series of 10 Cases
Harata Yuzu, Imai Kazuhiro, Takashima Shinogu, Kuriyama Shoji, Iwai Hidenobu, Suzuki Haruka, Demura Ryo, Shibano Sumire, Minamiya Yoshihiro
Surgical Case Reports ( 一般社団法人 日本外科学会 ) 11 ( 1 ) n/a 2025
<p><b>INTRODUCTION:</b> Extracorporeal membrane oxygenation (ECMO) is a type of extracorporeal circulation used to divert blood from and deliver blood to peripheral blood vessels. Recently, the use of ECMO has been reported in various non-transplant surgeries. Particularly in tracheal surgeries, ECMO provides an unobstructed surgical field and enables safe induction of general anesthesia in difficult intubation cases. Here, we report on 10 cases of thoracic surgery in which ECMO was employed at our institution.</p><p><b>CASE PRESENTATION:</b> These 10 cases comprise 4 tracheal cancer surgeries, 2 lung cancer surgeries, and 1 case each of surgery for thyroid cancer, mediastinal cancer, tracheomalacia, and tracheobronchial injury. Veno-venous (VV)-ECMO is most often selected, but veno-arterial (VA)-ECMO is chosen when recirculation with VV-ECMO is unacceptable, when pulmonary artery bleeding needs to be controlled, or when cardiac support is necessary. Among the 10 presented cases, VV-ECMO was used in 8, while VA-ECMO was employed in 2. Three of these cases involved ECMO bailout due to dyspnea caused by airway stenosis. Six of the patients did not receive heparin maintenance. Of those, 1 was maintained on nafamostat mesilate, 2 were maintained on nafamostat mesilate after receiving a single dose of heparin, and 3 received only a single dose of heparin. In none of those cases did ECMO fail to maintain flow due to thrombus formation. A postoperative hemothorax occurred as one of the ECMO-related complications in Case 4. There were no perioperative cardiopulmonary complications, in-hospital deaths, or deaths within 30 days after surgery. One patient died from metastatic recurrence of non-small cell lung cancer 5 months after surgery, another from progression of disease in mediastinal anaplastic cancer 4 months after surgery, and the 3rd from upper gastrointestinal bleeding 2 years after surgery. The other 7 patients remain alive.</p><p><b>CONCLUSIONS:</b> ECMO is useful in tracheal surgery and in cases where intubation is difficult or dangerous, because it facilitates safe and accurate surgery. We also believe that individualized anticoagulant strategies can be safely implemented.</p>
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Harata Yuzu, Imai Kazuhiro, Takashima Shinogu, Kurihara Nobuyasu, Kuriyama Shoji, Minamiya Yoshihiro
The Journal of the Japanese Association for Chest Surgery ( The Japanese Association for Chest Surgery ) 38 ( 2 ) 99 - 105 2024.03
<p>The patient was a 74-year-old female diagnosed with primary hyperparathyroidism, due to elevated serum levels of calcium and intact parathyroid hormone. CT and <sup>99m</sup>Tc-MIBI SPECT indicated the presence of an ectopic mediastinal parathyroid adenoma, which prompted her referral to our department for its surgical resection. Based on CT, the nodule was buried within the mediastinal fat and would be difficult to identify during surgery. Therefore, radio-guidance with <sup>99m</sup>Tc-MIBI and monitoring of intact-PTH were used as intraoperative guides. The operation was performed by hybrid video-assisted thoracic surgery with a 6-cm incision in the 3<sup>rd</sup> intercostal space, and we resected the nodule buried in the superior mediastinal fat. The nodule showed high <sup>99m</sup>Tc accumulation, and the intact-PTH level decreased after 10 minutes following resection. This led us to conclude that complete resection had been achieved. The final pathological diagnosis was ectopic mediastinal parathyroid adenoma, and there has been no recurrence to date. This outcome suggests that intraoperative guidance using a radioisotope technique along with intact-PTH monitoring may enable more precise excision of mediastinal ectopic parathyroid adenoma, and that accurate identification of the position of the nodule may reduce the rate of recurrence.</p>
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Tracheal bifurcation repair for blunt thoracic trauma in a patient with COVID-19
Shoji Kuriyama, Kazuhiro Imai, Kasumi Tozawa, Shinogu Takashima, Ryo Demura, Haruka Suzuki, Yuzu Harata, Tatsuki Fujibayashi, Sumire Shibano, Yoshihiro Minamiya
Surgical case reports 2023.06 [Refereed]
Single author
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Takahashi Shugo, Imai Kazuhiro, Takashima Shinogu, Atari Maiko, Kuriyama Shoji, Minamiya Yoshihiro
The Journal of the Japanese Association for Chest Surgery ( The Japanese Association for Chest Surgery ) 36 ( 4 ) 441 - 447 2022.05
<p>Anesthetic and surgical management of tracheal tumors is very challenging. Here, we report a 55-year-old female patient who underwent a 2-cm tracheal sleeve resection (the lower half of the 1st-2nd tracheal rings) and reconstruction safely and effectively with no complications on venovenous extracorporeal membrane oxygenation (VV-ECMO) support. Preoperative bronchoscopy revealed an 18-mm polypoid tumor with a smooth surface on the membranous portion of the upper trachea, where it caused airway obstruction and stridor. The tracheal tumor was histopathologically diagnosed as an inflammatory myofibroblastic tumor. ECMO set up during spontaneous breathing before the induction of general anesthesia is very useful for patients at high risk of airway blockage by a tracheal tumor. ECMO markedly contributed to securing respiratory control during the airway surgery and surgical field control. Its rate of associated complications, such as bleeding, is acceptable.</p>
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Right upper lobectomy for lung cancer with a supernumerary tracheal bronchus: A case report
Kuriyama Shoji, Kimura Daisuke, Minakawa Masahito, Minamiya Yoshihiro
The Journal of the Japanese Association for Chest Surgery ( The Japanese Association for Chest Surgery ) 36 ( 2 ) 144 - 149 2022.03
<p>A 79-year-old man was referred to our hospital with an abnormal shadow on a chest radiograph. Chest computed tomography (CT) showed a solid nodule in the right upper lobe, and a supernumerary anomalous bronchus arising from the trachea in addition to the normal right upper bronchus. Right upper lobectomy was performed with a diagnosis of primary lung adenocarcinoma Stage IA2. The supernumerary bronchus branched from the cranial side of the azygos vein arch through the caudal side to the right upper lobe between S<sup>2</sup> and S<sup>3</sup>. After dissecting the azygos vein arch, the supernumerary bronchus was dissected close to the trachea. Three-dimensional (3D) CT was useful for detecting bronchial and vascular anomalies.</p>
◆Original paper【 display / non-display 】
◆Other【 display / non-display 】
Grant-in-Aid for Scientific Research 【 display / non-display 】
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Grant-in-Aid for Scientific Research(C)
Project Year： 2025.04 - 2028.03
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Grant-in-Aid for Early-Career Scientists
Project Year： 2024.04 - 2027.03
Presentations 【 display / non-display 】
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The Postoperative Impacts of Inferior Pulmonary Ligament Division During Upper Lobectomy
Shoji Kuriyama, Kazuhiro Imai, Shinogu Takashima, Nobuyasu Kurihara, Ryo Demura, Haruka Suzuki, Yuzu Harata, Yoshihiro Minamiya
日本胸部外科学会定期学術集会 2022.11 - 2022.11
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Using CT to evaluate organ invasion by thymic epithelial tumors: measurement of the interface between the tumor and neighboring structures
Shoji Kuriyama, Kazuhiro Imai, Shinogu Takashima, Maiko Atari, Yoshiaki Ishii, Akihito Kobayashi, Shugo Takahashi, Yuzu Harata, Yoshihiro Minamiya
日本胸部外科学会定期学術集会 2021.10 - 2021.11