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International Journal of Environmental Research and Public Health ( International Journal of Environmental Research and Public Health ) 19 ( 24 ) 2022.12 [Refereed]

Research paper (journal)

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Intravascular Administration of Acridine Orange and Zoledronate in a Bone Metastasis Model of Breast Cancer

Shoji R.

Anticancer Research ( Anticancer Research ) 42 ( 11 ) 5357 - 5363 2022.11 [Refereed]

Research paper (journal)

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Degenerative Lumbar Spondylolisthesis Patients With Movement-related Low Back Pain Have Less Postoperative Satisfaction After Decompression Alone

Hirota R.

Spine ( Spine ) 47 ( 19 ) 1391 - 1398 2022.10 [Refereed]

Research paper (journal)

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Earlier appearance of Risser sign on ultrasound versus radiograph in adolescent idiopathic scoliosis

Hongo M.

Journal of Clinical Imaging Science ( Journal of Clinical Imaging Science ) 12 2022.07 [Refereed]

Research paper (journal)

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Development of New Mouse Breast Cancer Model of Local Bone Metastasis and Verification Using Bisphosphonates

Shoji R.

In Vivo ( In Vivo ) 36 ( 2 ) 667 - 671 2022.03 [Refereed]

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Curve progression and risk factors in patients of adolescent idiopathic scoliosis with Risser sign grade 4

Wakabayashi Rena, Hongo Michio, Misawa Akiko, Kimura Ryota, Kudo Daisuke, Shimada Yoichi, Miyakoshi Naohisa

Journal of Spine Research ( The Japanese Society for Spine Surgery and Related Research ) 14 ( 11 ) 1377 - 1382 2023.11

Introduction: Brace treatment for adolescent idiopathic scoliosis (AIS) is usually indicated for patients with Risser sign grade 0-3, but not for above grade 4. However, we occasionally see patients whose curves progress even in patients with Risser sign grade 4. We examine Cobb angle progression and risk factors in Risser sign grade 4 cases of AIS.Methods: From January 2016 to December 2020, 42 AIS patients with Risser sign grade 4 at the first visit to our clinic and were followed up for at least 1 year were included. Patient background, physical findings, and radiological measurements including the Cobb angles were evaluated. Patients were divided into progressive and non-progressive groups to compare their risk factors of scoliosis.Results: Eight patients were in the progressive group and 34 were in the non-progressive group. In the progressive group, the Cobb angle increased by 7.1 degrees, from 28.7 to 35.8 degrees. The time since menarche was significantly shorter in the progressive group (9.7 months) than in the non-progressive group (24.2 months) (P=0.003). Growth in height was significantly greater in the progressive group (+2.9 cm) than in the non-progressive group (+1.8 cm) (P = 0.02). There were no differences in the other factors.Conclusions: In this study, curves progressed in approximately 20% of patients with Risser sign grade 4. In cases with short time since menarche or potential for height growth, AIS patients with Risser sign grade 4 may need to take brace therapy.

DOI CiNii Research

Status and issue of scoliosis screening in Akita

Misawa Akiko, Hongo Michio, Kudo Daisuke, Wakabayashi Rena, Kimura Ryota, Shimada Yoichi, Miyakoshi Naohisa

Journal of Spine Research ( The Japanese Society for Spine Surgery and Related Research ) 14 ( 11 ) 1366 - 1371 2023.11

Introduction: In Akita Prefecture, school screening using the Moiré topography have been conducted since 1984, and have been continued after the start of musculoskeletal screening. In this study, we compared the results of the scoliosis examination using the Moiré screening with those of the musculoskeletal screening using data provided by the Akita City Board of Education.Methods: From 2017 to 2020, 1,442 patients with spinal column findings in musculoskeletal screening and 474 patients with Moiré screening findings underwent secondary examination.Results: The positive predictive value for the Cobb angle of 10 degrees or more was 39% in the musculoskeletal screening, and 60% in the Moiré screening. The positive predictive value of scoliosis in junior high school students was 57% for the musculoskeletal screening, which was similar to that for the Moiré screening. 13% of the diagnosed cases were newly positive for the musculoskeletal screening and 87% were continuously positive, and most of the cases were diagnosed with scoliosis by the Moiré screening.Conclusions: The results of this study have once again demonstrated the usefulness of Moiré screening in comparison with musculoskeletal screening. In order to promote the use of Moiré screening, it is necessary to improve the follow-up system after the screening. In addition, it is necessary to approach and cooperate with boards of education and medical associations for the development of medical checkups to resolve issues such as the protection of personal information in order to provide feedback on the results of medical checkups.

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Diagnosis and Surgical Treatment of Thoracic Dorsal Arachnoid Web: A Report of Two Cases.

Junichi Inoue, Naohisa Miyakoshi, Michio Hongo, Takashi Kobayashi, Toshiki Abe, Kazuma Kikuchi, Eiji Abe, Yuji Kasukawa, Yoshinori Ishikawa, Daisuke Kudo, Hayato Kinoshita, Ryota Kimura, Yoichi Shimada

Case reports in orthopedics 2020 8816598 - 8816598 2020

INTRODUCTION: An arachnoid web (AW) is a relatively rare disease and shows clinical symptoms and radiological findings similar to those of an arachnoid cyst (AC) or spinal cord herniation (SCH). Since the operative procedures for an AW are generally different from those intrathecal disorders, correct preoperative differential diagnosis is important. The purposes of this study were to report the usefulness of magnetic resonance imaging (MRI) and computed tomography (CT) myelography for diagnosing AW and to show the histological findings and clinical results. Case Description. Two patients, a 79-year-old man and a 43-year-old woman, are presented. The primary diagnoses were AC with ossification of the ligamentum flavum and epidural hematoma, respectively, in previous hospitals. They were finally diagnosed by the characteristic MRI and CT myelogram finding called the "scalpel sign." Histological findings showed epithelial cells and fibrous tissue derived from arachnoid tissues and microcalcifications. After surgery, the scalpel sign has vanished, and aggravation of their symptoms was prevented. CONCLUSION: An AW is refractory, but early detection by MRI and CT myelography and early treatment improve outcomes after surgery.

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The Cutting-edge Rehabilitation Treatment for Patients with Spinal Cord Injury:Functional Electrical Stimulation(FES)

Matsunaga Toshiki, Miyakoshi Naohisa, Kudo Daisuke, Saito Kimio, Kimura Ryota, Inoue Junichi, Chida Satoaki, Hatakeyama Kazutoshi, Shimada Yoichi

The Japanese Journal of Rehabilitation Medicine ( The Japanese Association of Rehabilitation Medicine ) 56 ( 7 ) 555 - 559 2019.07

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Posterior spinal fusion using a unilateral C1 posterior arch screw and a C2 laminar screw for atlantoaxial fracture dislocation.

Yuichi Ono, Naohisa Miyakoshi, Michio Hongo, Yuji Kasukawa, Yoshinori Ishikawa, Daisuke Kudo, Ryota Kimura, Jumpei Iida, Yoichi Shimada

SAGE open medical case reports 7 2050313X19849276 2019

INTRODUCTION: C1 lateral mass screws and C2 pedicle screws are usually chosen to fix atlantoaxial (C1-C2) instability. However, there are a few situations in which these screws are difficult to use, such as in a case with a fracture line at the screw insertion point and bleeding from the fracture site. A new technique using a unilateral C1 posterior arch screw and a C2 laminar screw combined with a contralateral C1 lateral mass screws-C2 pedicle screws procedure for upper cervical fixation is reported. CASE REPORT: A 24-year-old woman had an irreducible C1-C2 anterior dislocation with a type III odontoid fracture on the right side due to a traffic accident. The patient underwent open reduction and posterior C1-C2 fixation. On the left side, a C1 lateral mass screws and a C2 pedicle screws were placed. Because there was bleeding from the fracture site and a high-riding vertebral artery was seen on the right side, a C1 posterior arch screw and a C2 laminar screw were chosen. Eight months after the surgery, computed tomography scans showed healing of the odontoid fracture with anatomically correct alignment. CONCLUSIONS: Although there have been few comparable studies, fixation with unilateral C1 posterior arch screw-C2 laminar screw could be a beneficial choice for surgeries involving the upper cervical region in patients with fracture dislocation or arterial abnormalities.

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