Research Achievements - Original paper -

Fluvoxamine rescues mitochondrial Ca2+ transport and ATP production through σ1-receptor in hypertrophic cardiomyocytes

Hideaki Tagashira，Md Shenuarin Bhuiyan，Norifumi Shioda，Kohji Fukunaga

Life Sciences   95 ( 2 ) 89 - 100   2014.01  [Refereed]

Research paper (journal)   Domestic Co-author

Diverse regulation of IP3 and ryanodine receptors by pentazocine through σ1-receptor in cardiomyocytes

Hideaki Tagashira，Md Shenuarin Bhuiyan，Kohji Fukunaga

American Journal of Physiology - Heart and Circulatory Physiology   305 ( 8 ) 1201 - 1212   2013.10  [Refereed]

Research paper (journal)   Domestic Co-author

Stimulation of σ(1)-receptor restores abnormal mitochondrial Ca(2+) mobilization and ATP production following cardiac hypertrophy

Hideaki Tagashira，Chen Zhang，Ying-Mei Lu，Hideyuki Hasegawa，Hiroshi Kanai，Feng Han，Kohji Fukunaga

Biochimica et Biophysica Acta   1830 ( 4 ) 3082 - 3094   2013.04  [Refereed]

Research paper (journal)   International Co-author

Stimulation of the Sigma-1 Receptor by DHEA Enhances Synaptic Efficacy and Neurogenesis in the Hippocampal Dentate Gyrus of Olfactory Bulbectomized Mice

Shigeki Moriguchi，Yasuharu Shinoda，Yui Yamamoto，Yuzuru Sasaki，Kosuke Miyajima，Hideaki Tagashira，Kohji Fukunaga

PLoS One   8 ( 4 ) e60863   2013.04  [Refereed]

Research paper (journal)   Domestic Co-author

Novel nootropic drug sunifiram improves cognitive deficits via CaM kinase II and protein kinase C activation in olfactory bulbectomized mice

Shigeki Moriguchi，Tomoya Tanaka，Hideaki Tagashira，Toshio Narahashi，Kohji Fukunaga

Behavioural Brain Research   242   150 - 157   2013.04  [Refereed]

Research paper (journal)   Domestic Co-author

Vascular endothelial σ1-receptor stimulation with SA4503 rescues aortic relaxation via Akt/eNOS signaling in ovariectomized rats with aortic banding

Hideaki Tagashira，Takayuki Matsumoto，Kumiko Taguchi，Chen Zhang，Feng Han，Keiko Ishida，Shingo Nemoto，Tsuneo Kobayashi，Kohji Fukunaga

Circulation Journal   77 ( 11 ) 2831 - 2840   2013.03  [Refereed]

Research paper (journal)   International Co-author

Crucial Interactions Between Selective Serotonin Uptake Inhibitors and Sigma-1 Receptor in Heart Failure

Md Shenuarin Bhuiyan，Hideaki Tagashira，Kohji Fukunaga

Journal of Pharmacological Sciences   121 ( 3 ) 177 - 184   2013.01  [Refereed]

Research paper (journal)   Domestic Co-author

Expression of a truncated form of the endoplasmic reticulum chaperone protein, sigma-1 receptor, promotes mitochondrial energy depletion and apoptosis

Norifumi Shioda，Kiyoshi Ishikawa，Hideaki Tagashira，Toru Ishizuka，Hiromu Yawo，Kohji Fukunaga

Journal of Biological Chemistry   287 ( 28 ) 23318 - 23331   2012.07  [Refereed]

Research paper (journal)   Domestic Co-author

The T-type voltage-gated calcium channel as a molecular target of the novel cognitive enhancer ST101: Enhancement of long-term potentiation and CaMKII autophosphorylation in rat cortical slices

Shigeki Moriguchi，Norifumi Shioda，Yui Yamamoto，Hideaki Tagashira，Kohji Fukunaga

Journal of Neurochemistry   121 ( 1 ) 44 - 53   2012.04  [Refereed]

Research paper (journal)   Domestic Co-author

Distinct cardioprotective effects of 17beta-estradiol and dehydroepiandrosterone on pressure-overload-induced hypertrophy in ovariectomized female rats

Hideaki Tagashira，Shenuarin Bhuiyan，Norifumi Shioda，Kohji Fukunaga

Menopause   18 ( 12 ) 1317 - 1326   2011.12  [Refereed]

Research paper (journal)   Domestic Co-author

Dehydroepiandrosterone mediated stimulation of sigma-1 receptor activates Akt-eNOS signaling in the thoracic aorta of ovariectomized rats with abdominal aortic banding

Md Shenuarin Bhuiyan，Hideaki Tagashira，Kohji Fukunaga

Cardiovascular Therapeutics   29 ( 4 ) 219 - 230   2011.08  [Refereed]

Research paper (journal)   Domestic Co-author

Sigma-1 receptor stimulation with fluvoxamine activates Akt-eNOS signaling in the thoracic aorta of ovariectomized rats with abdominal aortic banding

Md Shenuarin Bhuiyan，Hideaki Tagashira，Kohji Fukunaga

European Journal of Pharmacology   650 ( 2 ) 621 - 628   2011.01  [Refereed]

Research paper (journal)   Domestic Co-author

Sigma1-receptor stimulation with fluvoxamine ameliorates transverse aortic constriction-induced myocardial hypertrophy and dysfunction in mice

Hideaki Tagashira，Shenuarin Bhuiyan，Norifumi Shioda，Hideyuki Hasegawa， Hiroshi Kanai，Kohji Fukunaga

American Journal of Physiology - Heart and Circulatory Physiology   299 ( 5 ) 1535 - 1545   2010.11  [Refereed]

Research paper (journal)   Domestic Co-author

Targeting sigma-1 receptor with fluvoxamine ameliorates pressure-overload-induced hypertrophy and dysfunctions

Md Shenuarin Bhuiyan，Hideaki Tagashira，Norifumi Shioda，Kohji Fukunaga

Expert Opinion on Therapeutic Targets   14 ( 10 ) 1009 - 1022   2010.10  [Refereed]

Research paper (journal)   Domestic Co-author

Magnolol and honokiol prevent learning and memory impairment and cholinergic deficit in SAMP8 mice

Nobuaki Matsui，Kazuki Takahashi，Miho Takeichi，Touma Kuroshita，Kaori Noguchi，Kana Yamazaki，Hideaki Tagashira，Kenichi Tsutsui，Hideki Okada，Yuki Kido，Yumiko Yasui，Nobuyuki Fukuishi，Yoshiyasu Fukuyama，Masaaki Akagi

Brain Research   1305   108 - 117   2009.12  [Refereed]

Research paper (journal)   Domestic Co-author