Research Achievements - Original paper -

Cardioprotective effects of Moku-boi-to and its impact on AngII-induced cardiomyocyte hypertrophy

Tagashira H, Abe F, Sato-Numata K, Aizawa K, Hirasawa K, Kure Y, Iwata D, Numata T.

Front Cell Dev Biol.     2023.11  [Refereed]

Research paper (journal)   Domestic Co-author

DOI

Perineural treatment with anti-TNF-α antibody ameliorates persistent allodynia and edema in novel mouse models with complex regional pain syndrome.

Shibata S, Tagashira H, Nemoto T, Kita S, Kita T, Shinoda Y, Akiyoshi K, Yamaura K, Iwamoto T.

J Pharmacol Sci.   153 ( 1 ) 1 - 11   2023.09  [Refereed]

Research paper (journal)   Domestic Co-author

DOI

Functional characteristics and therapeutic potential of SLC41 transporters.

Nemoto T, Tagashira H, Kita T, Kita S, Iwamoto T.

J Pharmacol Sci.   151 ( 2 ) 88 - 92   2023.02  [Refereed]

Research paper (journal)   Domestic Co-author

DOI

Lymphangiogenesis and angiogenesis rescue murine ischemic hindlimb via transient receptor potential vanilloid 4

Hideaki Yamada，Naoaki Sakata，Tomoko Tanaka，Hideaki Tagashira，Gumpei Yoshimatsu，Ryo Kawakami，Hideichi Wada，Takahiro Iwamoto，Shohta Kodama

Journal of Pharmacological Sciences   146 ( 4 ) 244 - 248   2021.08  [Refereed]

Research paper (journal)   Domestic Co-author

Na⁺/Ca²⁺ exchanger mediates cold Ca²⁺ signaling conserved for temperature-compensated circadian rhythms

Naohiro Kon，Hsin-Tzu Wang，Yoshiaki S Kato，Kyouhei Uemoto，Naohiro Kawamoto，Koji Kawasaki，Ryosuke Enoki，Gen Kurosawa，Tatsuto Nakane, Yasunori Sugiyama，Hideaki Tagashira，Motomu Endo，Hideo Iwasaki，Takahiro Iwamoto，Kazuhiko Kume，Yoshitaka Fukada

Science Advances   7 ( 18 ) eabe8132   2021.04  [Refereed]

Research paper (journal)   Domestic Co-author

Genetic knockout and pharmacologic inhibition of NCX1 attenuate hypoxia-induced pulmonary arterial hypertension

Asahi Nagata，Hideaki Tagashira (co-first author)，Satomi Kita，Tomo Kita，Naoko Nakajima，Kohtaro Abe，Akinori Iwasaki，Takahiro Iwamoto

Biochemical and Biophysical Research Communications   529 ( 3 ) 793 - 798   2020.08  [Refereed]

Research paper (journal)   Domestic Co-author

Sodium-calcium Exchanger 1 Is the Key Molecule for Urinary Potassium Excretion Against Acute Hyperkalemia

Wakana Shoda，Naohiro Nomura，Fumiaki Ando，Hideaki Tagashira，Takahiro Iwamoto，Akihito Ohta，Kiyoshi Isobe，Takayasu Mori，Koichiro Susa，Eisei Sohara，Tatemitsu Rai，Shinichi Uchida

PLoS One   15 ( 6 ) e0235360   2020.06  [Refereed]

Research paper (journal)   Domestic Co-author

Pharmacological exercise using a computer simulation of isolated preparation of guinea-pig ileum

Takayuki Nemoto，Hideaki Tagashira (co-first author)，Tomo Kita，Shiho Shibata，Naoko Nakajima，Yusuke Gotoh，Satomi Kita，Takahiro Iwamoto

Medical Bulletin of Fukuoka University   47 ( 1 ) 93 - 99   2020.03  [Refereed]

Research paper (journal)   Domestic Co-author

Reduced CaM Kinase II and CaM Kinase IV Activities Underlie Cognitive Deficits in NCKX2 Heterozygous Mice

Shigeki Moriguchi，Satomi Kita，Yasushi Yabuki，Ryo Inagaki，Hisanao Izumi，Yuzuru Sasaki，Hideaki Tagashira，Kyoji Horie，Junji Takeda，Takahiro Iwamoto，Kohji Fukunaga

Molecular Neurobiology   55 ( 5 ) 3889 - 3900   2018.05  [Refereed]

Research paper (journal)   Domestic Co-author

Calcium Signaling Abnormality in Pulmonary Arterial Hypertension

Hideaki Tagashira，Asahi Nagata，Satomi Kita，Sari Suzuki，Akinori Iwasaki，Takahiro Iwamoto

Medical Bulletin of Fukuoka University   45 ( 1 ) 175 - 181   2018.03  [Refereed]

Research paper (journal)   Domestic Co-author

Blockade of the KATP channel Kir6.2 by memantine represents a novel mechanism relevant to Alzheimer's disease therapy

Shigeki Moriguchi，Toru Ishizuka，Yasushi Yabuki，Norifumi Shioda，Yuzuru Sasaki，Hideaki Tagashira，Hiromu Yawo，Jay Z Yeh，Hiroyuki Sakagami，Toshio Narahashi，Kohji Fukunaga

Molecular Psychiatry   23 ( 2 ) 211 - 221   2018.02  [Refereed]

Research paper (journal)   Domestic Co-author

Corticosteroids Mediate Heart Failure-Induced Depression through Reduced σ1-Receptor Expression

Yasuharu Shinoda，Hideaki Tagashira (co-first author)，Md Shenuarin Bhuiyan，Hideyuki Hasegawa，Hiroshi Kanai，Chen Zhang，Feng Han，Kohji Fukunaga

PLoS One   11 ( 10 ) e0163992   2016.10  [Refereed]

Research paper (journal)   Domestic Co-author

Haloperidol aggravates transverse aortic constriction-induced heart failure via mitochondrial dysfunction

Yasuharu Shinoda，Hideaki Tagashira (co-first author)，Md Shenuarin Bhuiyan，Hideyuki Hasegawa，Hiroshi Kanai，Kohji Fukunaga

Journal of Pharmacological Sciences   131 ( 3 ) 172 - 183   2016.07  [Refereed]

Research paper (journal)   International Co-author

Yusuke Gotoh，Satomi Kita，Makoto Fujii，Hideaki Tagashira，Ichiro Horie，Yuji Arai，Shinichi Uchida，Takahiro Iwamoto

Yusuke Gotoh，Satomi Kita，Makoto Fujii，Hideaki Tagashira，Ichiro Horie，Yuji Arai，Shinichi Uchida，Takahiro Iwamoto

Biochemical and Biophysical Research Communications   456 ( 2 ) 670 - 675   2015.01  [Refereed]

Research paper (journal)   Domestic Co-author

The role of SIGMAR1 gene mutation and mitochondrial dysfunction in amyotrophic lateral sclerosis

Kohji Fukunaga，Yasuharu Shinoda，Hideaki Tagashira

Journal of Pharmacological Sciences   127 ( 1 ) 36 - 41   2015.01  [Refereed]

Research paper (journal)   Domestic Co-author

Methyl pyruvate rescues mitochondrial damage caused by SIGMAR1 mutation related to amyotrophic lateral sclerosis

Hideaki Tagashira，Yasuharu Shinoda，Norifumi Shioda，Kohji Fukunaga

Biochimica et Biophysica Acta   1840 ( 12 ) 3320 - 3334   2014.12  [Refereed]

Research paper (journal)   International Co-author

Rivastigmine restores 5-HT1A receptor levels in the hippocampus of olfactory bulbectomized mice

Md. Rashedul Islam，Shigeki Moriguchi，Hideaki Tagashira，Kohji Fukunaga

Advances in Alzheimer's Disease   3 ( 3 ) 128 - 136   2014.09  [Refereed]

Research paper (journal)   Domestic Co-author

Rivastigmine improves hippocampal neurogenesis and depression-like behaviors via 5-HT1A receptor stimulation in olfactory bulbectomized mice

Md. Rashedul Islam，Shigeki Moriguchi，Hideaki Tagashira，Kohji Fukunaga

Neuroscience   272   116 - 130   2014.07  [Refereed]

Research paper (journal)   Domestic Co-author

Ultrasonic visualization of propagation of myocardial vibration driven by electrical excitation of myocardium of rat in ex vivo experiment

Yuta Fujita，Hideaki Tagashira，Hideyuki Hasegawa，Kohji Fukunaga，Hiroshi Kanai

Japanese Journal of Applied Physics   53 ( 7 ) 07KF25-1 - 07KF25-7   2014.06  [Refereed]

Research paper (journal)   Domestic Co-author

CaMKII activity is essential for improvement of memory-related behaviors by chronic rivastigmine treatment

Shigeki Moriguchi，Hideaki Tagashira，Yuzuru Sasaki，Jay Z Yeh，Hiroyuki Sakagami，Toshio Narahashi，Kohji Fukunaga

Journal of Neurochemistry   128 ( 6 ) 927 - 937   2014.03  [Refereed]

Research paper (journal)   Domestic Co-author

Fluvoxamine rescues mitochondrial Ca2+ transport and ATP production through σ1-receptor in hypertrophic cardiomyocytes

Hideaki Tagashira，Md Shenuarin Bhuiyan，Norifumi Shioda，Kohji Fukunaga

Life Sciences   95 ( 2 ) 89 - 100   2014.01  [Refereed]

Research paper (journal)   Domestic Co-author

Diverse regulation of IP3 and ryanodine receptors by pentazocine through σ1-receptor in cardiomyocytes

Hideaki Tagashira，Md Shenuarin Bhuiyan，Kohji Fukunaga

American Journal of Physiology - Heart and Circulatory Physiology   305 ( 8 ) 1201 - 1212   2013.10  [Refereed]

Research paper (journal)   Domestic Co-author

Stimulation of σ(1)-receptor restores abnormal mitochondrial Ca(2+) mobilization and ATP production following cardiac hypertrophy

Hideaki Tagashira，Chen Zhang，Ying-Mei Lu，Hideyuki Hasegawa，Hiroshi Kanai，Feng Han，Kohji Fukunaga

Biochimica et Biophysica Acta   1830 ( 4 ) 3082 - 3094   2013.04  [Refereed]

Research paper (journal)   International Co-author

Stimulation of the Sigma-1 Receptor by DHEA Enhances Synaptic Efficacy and Neurogenesis in the Hippocampal Dentate Gyrus of Olfactory Bulbectomized Mice

Shigeki Moriguchi，Yasuharu Shinoda，Yui Yamamoto，Yuzuru Sasaki，Kosuke Miyajima，Hideaki Tagashira，Kohji Fukunaga

PLoS One   8 ( 4 ) e60863   2013.04  [Refereed]

Research paper (journal)   Domestic Co-author

Novel nootropic drug sunifiram improves cognitive deficits via CaM kinase II and protein kinase C activation in olfactory bulbectomized mice

Shigeki Moriguchi，Tomoya Tanaka，Hideaki Tagashira，Toshio Narahashi，Kohji Fukunaga

Behavioural Brain Research   242   150 - 157   2013.04  [Refereed]

Research paper (journal)   Domestic Co-author

Vascular endothelial σ1-receptor stimulation with SA4503 rescues aortic relaxation via Akt/eNOS signaling in ovariectomized rats with aortic banding

Hideaki Tagashira，Takayuki Matsumoto，Kumiko Taguchi，Chen Zhang，Feng Han，Keiko Ishida，Shingo Nemoto，Tsuneo Kobayashi，Kohji Fukunaga

Circulation Journal   77 ( 11 ) 2831 - 2840   2013.03  [Refereed]

Research paper (journal)   International Co-author

Crucial Interactions Between Selective Serotonin Uptake Inhibitors and Sigma-1 Receptor in Heart Failure

Md Shenuarin Bhuiyan，Hideaki Tagashira，Kohji Fukunaga

Journal of Pharmacological Sciences   121 ( 3 ) 177 - 184   2013.01  [Refereed]

Research paper (journal)   Domestic Co-author

Expression of a truncated form of the endoplasmic reticulum chaperone protein, sigma-1 receptor, promotes mitochondrial energy depletion and apoptosis

Norifumi Shioda，Kiyoshi Ishikawa，Hideaki Tagashira，Toru Ishizuka，Hiromu Yawo，Kohji Fukunaga

Journal of Biological Chemistry   287 ( 28 ) 23318 - 23331   2012.07  [Refereed]

Research paper (journal)   Domestic Co-author

The T-type voltage-gated calcium channel as a molecular target of the novel cognitive enhancer ST101: Enhancement of long-term potentiation and CaMKII autophosphorylation in rat cortical slices

Shigeki Moriguchi，Norifumi Shioda，Yui Yamamoto，Hideaki Tagashira，Kohji Fukunaga

Journal of Neurochemistry   121 ( 1 ) 44 - 53   2012.04  [Refereed]

Research paper (journal)   Domestic Co-author

Distinct cardioprotective effects of 17beta-estradiol and dehydroepiandrosterone on pressure-overload-induced hypertrophy in ovariectomized female rats

Hideaki Tagashira，Shenuarin Bhuiyan，Norifumi Shioda，Kohji Fukunaga

Menopause   18 ( 12 ) 1317 - 1326   2011.12  [Refereed]

Research paper (journal)   Domestic Co-author

Dehydroepiandrosterone mediated stimulation of sigma-1 receptor activates Akt-eNOS signaling in the thoracic aorta of ovariectomized rats with abdominal aortic banding

Md Shenuarin Bhuiyan，Hideaki Tagashira，Kohji Fukunaga

Cardiovascular Therapeutics   29 ( 4 ) 219 - 230   2011.08  [Refereed]

Research paper (journal)   Domestic Co-author

Sigma-1 receptor stimulation with fluvoxamine activates Akt-eNOS signaling in the thoracic aorta of ovariectomized rats with abdominal aortic banding

Md Shenuarin Bhuiyan，Hideaki Tagashira，Kohji Fukunaga

European Journal of Pharmacology   650 ( 2 ) 621 - 628   2011.01  [Refereed]

Research paper (journal)   Domestic Co-author

Sigma1-receptor stimulation with fluvoxamine ameliorates transverse aortic constriction-induced myocardial hypertrophy and dysfunction in mice

Hideaki Tagashira，Shenuarin Bhuiyan，Norifumi Shioda，Hideyuki Hasegawa， Hiroshi Kanai，Kohji Fukunaga

American Journal of Physiology - Heart and Circulatory Physiology   299 ( 5 ) 1535 - 1545   2010.11  [Refereed]

Research paper (journal)   Domestic Co-author

Targeting sigma-1 receptor with fluvoxamine ameliorates pressure-overload-induced hypertrophy and dysfunctions

Md Shenuarin Bhuiyan，Hideaki Tagashira，Norifumi Shioda，Kohji Fukunaga

Expert Opinion on Therapeutic Targets   14 ( 10 ) 1009 - 1022   2010.10  [Refereed]

Research paper (journal)   Domestic Co-author

Magnolol and honokiol prevent learning and memory impairment and cholinergic deficit in SAMP8 mice

Nobuaki Matsui，Kazuki Takahashi，Miho Takeichi，Touma Kuroshita，Kaori Noguchi，Kana Yamazaki，Hideaki Tagashira，Kenichi Tsutsui，Hideki Okada，Yuki Kido，Yumiko Yasui，Nobuyuki Fukuishi，Yoshiyasu Fukuyama，Masaaki Akagi

Brain Research   1305   108 - 117   2009.12  [Refereed]

Research paper (journal)   Domestic Co-author