研究者詳細 - 岩瀬　剛

研究等業績 - その他 - 岩瀬　剛

分割表示 81 件中 21 - 40 件目／全件表示 >>

Elevated retinal artery vascular resistance determined by novel visualized technique of laser speckle flowgraphy in branch retinal vein occlusion

Tomita R.

Scientific Reports ( Scientific Reports ) 11 ( 1 ) 20034 2021年12月

<jats:title>Abstract</jats:title><jats:p>We aimed to investigate the increase in resistivity of the retinal artery in the branch retinal vein occlusion (BRVO)-affected area, and to visualize it. Thirty-two eyes of 32 patients with BRVO were measured by laser speckle flowgraphy (LSFG). The retinal artery and vein running to the BRVO-affected area and vertically symmetrical vessels in the unaffected area were examined. We applied the LSFG parameter beat strength over mean blur rate (BOM), calculated using a similar method to the pulsatility index used in Doppler flowmetry to evaluate resistivity of the vessels. Our results showed that the BOM map could clearly visualize the increase of resistivity in the retinal artery as a two-dimensional map. The BOM of the arteries in the affected area was significantly higher than that of the unaffected area (<jats:italic>P</jats:italic> = 0.001). Multiple regression analysis showed that the ratio of BOM in retinal arteries of the affected area to the unaffected was significantly associated with the extent of retinal hemorrhage (β = 0.447, <jats:italic>P</jats:italic> = 0.009). In conclusion, the index of resistivity of the retinal artery in the BRVO-affected area was higher and could be visualized in a two-dimensional map. These findings and techniques would contribute to elucidate the pathophysiology of BRVO.</jats:p>

DOI CiNii Research

Prevalence of and factors associated with dilated choroidal vessels beneath the retinal pigment epithelium among the Japanese

Ito Y.

Scientific Reports ( Scientific Reports ) 11 ( 1 ) 2021年12月

DOI

Regional and sex differences in retinal detachment surgery: Japan-retinal detachment registry report

Funatsu R.

Scientific Reports ( Scientific Reports ) 11 ( 1 ) 2021年12月

DOI

Association of changes of retinal vessels diameter with ocular blood flow in eyes with diabetic retinopathy

Ueno Y.

Scientific Reports ( Scientific Reports ) 11 ( 1 ) 4653 2021年12月

<jats:title>Abstract</jats:title><jats:p>We investigated morphological changes of retinal arteries to determine their association with the blood flow and systemic variables in type 2 diabetes patients. The patients included 47 non-diabetic retinopathy eyes, 36 mild or moderate nonproliferative diabetic retinopathy (M-NPDR) eyes, 22 severe NPDR (S-NPDR) eyes, 32 PDR eyes, and 24 normal eyes as controls. The mean wall to lumen ratio (WLR) measured by adaptive optics camera was significantly higher in the PDR groups than in all of the other groups (all <jats:italic>P</jats:italic> < 0.001). However, the external diameter of the retinal vessels was not significantly different among the groups. The mean blur rate (MBR)-vessel determined by laser speckle flowgraphy was significantly lower in the PDR group than in the other groups (<jats:italic>P</jats:italic> < 0.001). The WLR was correlated with MBR-vessel (<jats:italic>r</jats:italic> = − 0.337, <jats:italic>P</jats:italic> < 0.001), duration of disease (<jats:italic>r</jats:italic> = 0.191, <jats:italic>P</jats:italic> = 0.042), stage of DM (<jats:italic>r</jats:italic> = 0.643, <jats:italic>P</jats:italic> < 0.001), systolic blood pressure (<jats:italic>r</jats:italic> = 0.166, <jats:italic>P</jats:italic> < 0.037), and presence of systemic hypertension (<jats:italic>r</jats:italic> = 0.443, <jats:italic>P</jats:italic> < 0.001). Multiple regression analysis demonstrated that MBR-vessel (β = − 0.389, <jats:italic>P</jats:italic> < 0.001), presence of systemic hypertension (β = 0.334, <jats:italic>P</jats:italic> = 0.001), and LDL (β = 0.199, <jats:italic>P</jats:italic> = 0.045) were independent factors significantly associated with the WLR. The increased retinal vessel wall thickness led to a narrowing of lumen diameter and a decrease in the blood flow in the PDR group.</jats:p>

DOI CiNii Research

Nasal displacement of retinal vessels on the optic disc in glaucoma associated with a nasally angled passage through lamina cribrosa

Sawada Y.

Scientific Reports ( Scientific Reports ) 11 ( 1 ) 2021年12月

To investigate nasal displacement of central retinal vessel (CRV) on the optic nerve head (ONH) in glaucoma in association with its passage through lamina cribrosa (LC). This cross-sectional study included 113 eyes with glaucoma and 60 normal eyes. Horizontal spectral-domain optical coherence tomography (SD-OCT) scans of the ONH were acquired, and point where CRV emerged on the ONH surface was defined as the position of the CRV. Next, radial scans of the ONH were acquired, and angle of the CRV passing through the LC was measured. These parameters were compared between glaucomatous and normal eyes by t-test, and their relationship with possible confounders was assessed by multiple regression analyses. In glaucoma, CRV was significantly more nasally displaced than it was in normal eyes (66.0 +/- 8.6 vs. 54.3 +/- 9.5, P<0.0001), and eyes with more vessel displacement exhibited significantly worse glaucomatous visual field defects (P=0.0004). Greater nasal displacement of the CRV was significantly associated with a more nasally angled path through the LC (rs=0.569, P<0.0001). By using SD-OCT, we confirmed that nasal displacement of the CRV on the ONH was associated with glaucoma and was induced by its nasally angled path through the LC.

DOI CiNii Research

Four-year follow up of macular intrachoroidal cavitation and chorioretinal atrophy A case report

Abe S.

Medicine (United States) ( Medicine (United States) ) 100 ( 50 ) 2021年12月

DOI

Selective extension of cerebral vascular calcification in an autopsy case of Fahr's syndrome associated with asymptomatic hypoparathyroidism

Iwase T.

Neuropathology ( Neuropathology ) 41 ( 5 ) 387 - 395 2021年10月

DOI

Erratum to Association between retinal layer thickness and perfusion status in extramacular areas in diabetic retinopathy. Am J Ophthalmol 2020; 215:25–36 (American Journal of Ophthalmology (2020) 215 (25–36), (S0002939420301197), (10.1016/j.ajo.2020.03.019))

Ito H.

American Journal of Ophthalmology ( American Journal of Ophthalmology ) 227 2021年07月