研究者詳細 - 岩瀬　剛

Ocular trauma has been one of the leading causes of visual impairment, and choroidal avulsion is especially devastating. Surgical treatment of choroidal avulsion is challenging, and very few surgical techniques have been reported. We experienced two cases of globe rupture with 360-degree avulsion of the choroid-ciliary body from the peripheral section. After vitrectomy for a globe rupture, the choroid gradually slid down to the posterior pole over time and vision deteriorated even though the retina was attached. We treated the choroidal avulsion using two surgical methods: a mattress suturing technique using a 10-0 proline long needle and a 7-0 nylon single suture technique. In both methods, the retina-choroid, which had slipped down to the posterior pole, was suspended and fixed to the sclera assisted by a wide-angle viewing system, improving visual acuity. These two methods are considered to be useful surgical procedures for the treatment of an avulsed choroid.

DOI CiNii Research

ブリモニジン酒石酸塩点眼液使用中に角膜実質混濁が急速に進行した1例

小島創太, 岩瀬剛

臨床眼科 ( 医学書院 ) 76 ( 8 ) 1049 - 1053 2022年08月

CiNii Research

硝子体黄斑牽引症候群

岩瀬剛

Oculista = オクリスタ ( 全日本病院出版会 ) ( 113 ) 27 - 35 2022年08月

CiNii Research

臨床報告ブリモニジン酒石酸塩点眼液使用中に角膜実質混濁が急速に進行した1例

小島創太, 岩瀬剛

臨床眼科 ( 株式会社医学書院 ) 76 ( 8 ) 1049 - 1053 2022年08月

DOI CiNii Research

Differences in primary retinal detachment surgery conducted on holidays and workdays analyzed using the Japan Retinal Detachment Registry

Kawano S.

Japanese Journal of Ophthalmology ( Japanese Journal of Ophthalmology ) 66 ( 3 ) 271 - 277 2022年05月

DOI

Differences in Vascular Density between Detached and Nondetached Areas in Eyes with Rhegmatogenous Retinal Detachment

Sato M.

Journal of Clinical Medicine ( Journal of Clinical Medicine ) 11 ( 10 ) 2881 2022年05月

We examined the vessel density (VD) of the deep capillary plexus (DCP) and choriocapillaris plexus (CCP) by optical coherence tomography (OCT) angiography in eyes with rhegmatogenous retinal detachment, which had similar amounts of detached and nondetached areas in the macula region, and then determined the morphology by OCT until 6 months after surgery. A total of 13 eyes of 13 patients whose average age was 55.8 +/- 12.3 years and were successfully treated were enrolled in this study. Throughout the postoperative period, the VD of the DCP in the detached area decreased significantly compared to that in the nondetached area. Conversely, there was no significant difference in the VD of the CCP between the detached and the nondetached areas. The ratio of VD of both the DCP and CCP in the detached area to the in the nondetached area did not show significant changes during the follow-up period of 6 months. The ratio of VD of the DCP in the detached area to that in the nondetached area correlated significantly with the ratio of the external limiting membrane-ellipsoid zone (r = 0.57, p < 0.001) and ellipsoid zone-retinal pigment epithelium (r = 0.39, p < 0.001) thickness in the detached area to that in the nondetached area. A well-preserved DCP blood flow could result in the restoration of the outer retina.

DOI CiNii Research

網膜静脈閉塞症に対する手術治療

岩瀬剛

あたらしい眼科 / メディカル葵出版 [編] ( メディカル葵出版 ) 39 ( 1 ) 63 - 69 2022年01月

CiNii Research

Severe cerebrovascular pathology of the first supercentenarian to be autopsied in the world

Iwase T.

Neuropathology ( Neuropathology ) 2022年

DOI

Elevated retinal artery vascular resistance determined by novel visualized technique of laser speckle flowgraphy in branch retinal vein occlusion

Tomita R.

Scientific Reports ( Scientific Reports ) 11 ( 1 ) 20034 2021年12月

<jats:title>Abstract</jats:title><jats:p>We aimed to investigate the increase in resistivity of the retinal artery in the branch retinal vein occlusion (BRVO)-affected area, and to visualize it. Thirty-two eyes of 32 patients with BRVO were measured by laser speckle flowgraphy (LSFG). The retinal artery and vein running to the BRVO-affected area and vertically symmetrical vessels in the unaffected area were examined. We applied the LSFG parameter beat strength over mean blur rate (BOM), calculated using a similar method to the pulsatility index used in Doppler flowmetry to evaluate resistivity of the vessels. Our results showed that the BOM map could clearly visualize the increase of resistivity in the retinal artery as a two-dimensional map. The BOM of the arteries in the affected area was significantly higher than that of the unaffected area (<jats:italic>P</jats:italic> = 0.001). Multiple regression analysis showed that the ratio of BOM in retinal arteries of the affected area to the unaffected was significantly associated with the extent of retinal hemorrhage (β = 0.447, <jats:italic>P</jats:italic> = 0.009). In conclusion, the index of resistivity of the retinal artery in the BRVO-affected area was higher and could be visualized in a two-dimensional map. These findings and techniques would contribute to elucidate the pathophysiology of BRVO.</jats:p>

DOI CiNii Research

Prevalence of and factors associated with dilated choroidal vessels beneath the retinal pigment epithelium among the Japanese

Ito Y.

Scientific Reports ( Scientific Reports ) 11 ( 1 ) 2021年12月

DOI

Regional and sex differences in retinal detachment surgery: Japan-retinal detachment registry report

Funatsu R.

Scientific Reports ( Scientific Reports ) 11 ( 1 ) 2021年12月

DOI

Association of changes of retinal vessels diameter with ocular blood flow in eyes with diabetic retinopathy

Ueno Y.

Scientific Reports ( Scientific Reports ) 11 ( 1 ) 4653 2021年12月

<jats:title>Abstract</jats:title><jats:p>We investigated morphological changes of retinal arteries to determine their association with the blood flow and systemic variables in type 2 diabetes patients. The patients included 47 non-diabetic retinopathy eyes, 36 mild or moderate nonproliferative diabetic retinopathy (M-NPDR) eyes, 22 severe NPDR (S-NPDR) eyes, 32 PDR eyes, and 24 normal eyes as controls. The mean wall to lumen ratio (WLR) measured by adaptive optics camera was significantly higher in the PDR groups than in all of the other groups (all <jats:italic>P</jats:italic> < 0.001). However, the external diameter of the retinal vessels was not significantly different among the groups. The mean blur rate (MBR)-vessel determined by laser speckle flowgraphy was significantly lower in the PDR group than in the other groups (<jats:italic>P</jats:italic> < 0.001). The WLR was correlated with MBR-vessel (<jats:italic>r</jats:italic> = − 0.337, <jats:italic>P</jats:italic> < 0.001), duration of disease (<jats:italic>r</jats:italic> = 0.191, <jats:italic>P</jats:italic> = 0.042), stage of DM (<jats:italic>r</jats:italic> = 0.643, <jats:italic>P</jats:italic> < 0.001), systolic blood pressure (<jats:italic>r</jats:italic> = 0.166, <jats:italic>P</jats:italic> < 0.037), and presence of systemic hypertension (<jats:italic>r</jats:italic> = 0.443, <jats:italic>P</jats:italic> < 0.001). Multiple regression analysis demonstrated that MBR-vessel (β = − 0.389, <jats:italic>P</jats:italic> < 0.001), presence of systemic hypertension (β = 0.334, <jats:italic>P</jats:italic> = 0.001), and LDL (β = 0.199, <jats:italic>P</jats:italic> = 0.045) were independent factors significantly associated with the WLR. The increased retinal vessel wall thickness led to a narrowing of lumen diameter and a decrease in the blood flow in the PDR group.</jats:p>

DOI CiNii Research

Nasal displacement of retinal vessels on the optic disc in glaucoma associated with a nasally angled passage through lamina cribrosa

Sawada Y.

Scientific Reports ( Scientific Reports ) 11 ( 1 ) 2021年12月

To investigate nasal displacement of central retinal vessel (CRV) on the optic nerve head (ONH) in glaucoma in association with its passage through lamina cribrosa (LC). This cross-sectional study included 113 eyes with glaucoma and 60 normal eyes. Horizontal spectral-domain optical coherence tomography (SD-OCT) scans of the ONH were acquired, and point where CRV emerged on the ONH surface was defined as the position of the CRV. Next, radial scans of the ONH were acquired, and angle of the CRV passing through the LC was measured. These parameters were compared between glaucomatous and normal eyes by t-test, and their relationship with possible confounders was assessed by multiple regression analyses. In glaucoma, CRV was significantly more nasally displaced than it was in normal eyes (66.0 +/- 8.6 vs. 54.3 +/- 9.5, P<0.0001), and eyes with more vessel displacement exhibited significantly worse glaucomatous visual field defects (P=0.0004). Greater nasal displacement of the CRV was significantly associated with a more nasally angled path through the LC (rs=0.569, P<0.0001). By using SD-OCT, we confirmed that nasal displacement of the CRV on the ONH was associated with glaucoma and was induced by its nasally angled path through the LC.

DOI CiNii Research

Four-year follow up of macular intrachoroidal cavitation and chorioretinal atrophy A case report

Abe S.

Medicine (United States) ( Medicine (United States) ) 100 ( 50 ) 2021年12月

DOI

Selective extension of cerebral vascular calcification in an autopsy case of Fahr's syndrome associated with asymptomatic hypoparathyroidism

Iwase T.

Neuropathology ( Neuropathology ) 41 ( 5 ) 387 - 395 2021年10月

DOI

Erratum to Association between retinal layer thickness and perfusion status in extramacular areas in diabetic retinopathy. Am J Ophthalmol 2020; 215:25–36 (American Journal of Ophthalmology (2020) 215 (25–36), (S0002939420301197), (10.1016/j.ajo.2020.03.019))

Ito H.

American Journal of Ophthalmology ( American Journal of Ophthalmology ) 227 2021年07月

DOI

Sloping Shoulders Sign: A Practical Radiological Sign for the Differentiation of Alzheimer's Disease and Argyrophilic Grain Disease

Sakurai K.

Journal of Alzheimer's Disease ( Journal of Alzheimer's Disease ) 84 ( 4 ) 1719 - 1727 2021年

DOI

Rapid morphological restoration of normal foveal contour after spontaneous epiretinal membrane separation from retina in eye with macular pseudohole: A case report

Kamada R.

International Medical Case Reports Journal ( International Medical Case Reports Journal ) 14 211 - 214 2021年

DOI

Peripapillary choroidal thickness assessed by spectral-domain optical coherence tomography in normal Japanese

Shibata H.

Japanese Journal of Ophthalmology ( Japanese Journal of Ophthalmology ) 65 ( 5 ) 666 - 671 2021年

DOI

Two years outcomes of treating full-thickness macula hole associated with idiopathic macular telangiectasia type 2 by internal limiting membrane inverted flap technique Case reports

Nishiyama S.

Medicine (United States) ( Medicine (United States) ) 100 ( 36 ) 2021年

DOI

Correlation between blood flow on optic nerve head and structural and functional changes in eyes with glaucoma

Kuroda F.

Scientific Reports ( Scientific Reports ) 10 ( 1 ) 2020年12月

DOI

Correlations between intraretinal cystoid cavities and pre- and postoperative characteristics of eyes after closure of idiopathic macular hole

Goto K.

Scientific Reports ( Scientific Reports ) 10 ( 1 ) 2020年12月

DOI

Ⅶ.網膜硝子体 6.水晶体核落下

岩瀬剛

眼科 ( 金原出版 ) 62 ( 11 ) 1249 - 1253 2020年10月

DOI CiNii Research

Association Between Retinal Layer Thickness and Perfusion Status in Extramacular Areas in Diabetic Retinopathy

Ito H.

American Journal of Ophthalmology ( American Journal of Ophthalmology ) 215 25 - 36 2020年07月

DOI

糖尿病網膜症の病態と治療

岩瀬剛

秋田医学 ( 秋田医学会 ) 47 ( 1 ) 1 - 10 2020年06月

DOI CiNii Research

Japan-Retinal Detachment Registry Report I: preoperative findings in eyes with primary retinal detachment

Sakamoto T.

Japanese Journal of Ophthalmology ( Japanese Journal of Ophthalmology ) 64 ( 1 ) 1 - 12 2020年01月

DOI

特集画像が開く新しい眼科手術術中OCT画像の有用性

岩瀬剛

臨床眼科 ( 株式会社医学書院 ) 74 ( 1 ) 56 - 64 2020年01月

DOI CiNii Research

Relationship between abnormalities of photoreceptor microstructures and microvascular structures determined by optical coherence tomography angiography in eyes with branch retinal vein occlusion

Ogasawara Y.

Retina ( Retina ) 40 ( 2 ) 350 - 358 2020年

DOI

Correlation between preoperative factors and final visual acuity after successful rhegmatogenous retinal reattachment

Hirata N.

Scientific Reports ( Scientific Reports ) 9 ( 1 ) 2019年12月

DOI

Effect of intravitreal or sub-tenon triamcinolone acetonide injection at completion of vitrectomy on peripheral retinochoroidal thickness in eyes with proliferative diabetic retinopathy

Fujiwara Y.

Scientific Reports ( Scientific Reports ) 9 ( 1 ) 2019年12月

DOI

Inner macular changes after vitrectomy with internal limiting membrane peeling for rhegmatogenous retinal detachment: Similarity with alport syndrome

Fukukita H.

Retina ( Retina ) 39 ( 12 ) 2332 - 2340 2019年12月

DOI

増刊号実戦メディカル眼科治療アップデートメディカル眼科治療各論 Ⅵ 網膜硝子体疾患網膜静脈閉塞症

岩瀬剛

臨床眼科 ( 株式会社医学書院 ) 73 ( 11 ) 303 - 307 2019年10月

DOI CiNii Research

Multimodal Imaging in Bilateral Nature of the Choroidal Osteoma after Intraocular Inflammation Caused by Harada Disease

Ozawa K.

Retina ( Retina ) 39 ( 9 ) e40 - e41 2019年09月

DOI

Retinal degeneration after accidental intravitreal injection of ropivacaine during strabismus surgery

Iwase T.

Retina ( Retina ) 39 ( 7 ) E30 - E31 2019年07月

DOI

Evaluation of blood flow on optic nerve head after pattern scan and conventional laser panretinal photocoagulation

Iwase T.

Medicine (United States) ( Medicine (United States) ) 98 ( 24 ) 2019年06月

DOI

Influence of submacular fluid on recovery of retinal function and structure after successful rhegmatogenous retinal reattachment

Kobayashi M.

PLoS ONE ( PLoS ONE ) 14 ( 7 ) 2019年06月

DOI

Intracranial vascular calcification with extensive white matter changes in an autopsy case of pseudopseudohypoparathyroidism

Iwase T.

Neuropathology ( Neuropathology ) 39 ( 1 ) 39 - 46 2019年02月

DOI

Biological characteristics of subsilicone oil fluid and differences with other ocular humors

Shimizu H.

Translational Vision Science and Technology ( Translational Vision Science and Technology ) 8 ( 1 ) 2019年01月

DOI

Progress and perspectives in dry processes for emerging multidisciplinary applications: How can we improve our use of dry processes?

Iwase T.

Japanese Journal of Applied Physics ( Japanese Journal of Applied Physics ) 58 ( SE ) 2019年

DOI

Progress and perspectives in dry processes for leading-edge manufacturing of devices: Toward intelligent processes and virtual product development

Iwase T.

Japanese Journal of Applied Physics ( Japanese Journal of Applied Physics ) 58 ( SE ) 2019年

DOI

Progress and perspectives in dry processes for nanoscale feature fabrication: Fine pattern transfer and high-aspect-ratio feature formation

Iwase T.

Japanese Journal of Applied Physics ( Japanese Journal of Applied Physics ) 58 ( SE ) 2019年

DOI

A randomized clinical trial evaluating choroidal blood flow and morphology after conventional and pattern scan laser panretinal photocoagulation

Mikoshiba Y.

Scientific Reports ( Scientific Reports ) 8 ( 1 ) 2018年12月

DOI

Evaluation of optic nerve head blood flow in response to increase of intraocular pressure

Iwase T.

Scientific Reports ( Scientific Reports ) 8 ( 1 ) 2018年12月

DOI

Novel Classification of Early-stage Systemic Hypertensive Changes in Human Retina Based on OCTA Measurement of Choriocapillaris

Takayama K.

Scientific Reports ( Scientific Reports ) 8 ( 1 ) 2018年12月

DOI

Changes in choriocapillaris and retinal morphology after laser photocoagulation by OCT angiography: A case report

Iwase T.

Medicine (United States) ( Medicine (United States) ) 97 ( 46 ) 2018年11月

DOI

特集糖尿病網膜症の最新情報を読み解く５　硝子体手術～最新の治療成績,同時手術の適応,眼血流への影響

岩瀬剛

眼科 ( 金原出版 ) 60 ( 9 ) 905 - 911 2018年09月

DOI CiNii Research

硝子体手術 : 最新の治療成績,同時手術の適応,眼血流への影響

岩瀬剛

眼科 ( 金原出版 ) 60 ( 9 ) 905 - 911 2018年09月

CiNii Research

Cholesterol crystal embolism in which disappearance of retinal arterial embolic factor by medical treatment

Hatano T.

Folia Japonica de Ophthalmologica Clinica ( Folia Japonica de Ophthalmologica Clinica ) 11 ( 8 ) 593 - 595 2018年08月

Better prognosis for eyes with preserved foveal depression after intravitreal ranibizumab injection for macular edema secondary to central retinal vein occlusion

Kitagawa S.

Retina ( Retina ) 38 ( 7 ) 1354 - 1360 2018年07月

DOI

Macular Displacement After Vitrectomy in Eyes With Idiopathic Macular Hole Determined by Optical Coherence Tomography Angiography

Akahori T.

American Journal of Ophthalmology ( American Journal of Ophthalmology ) 189 111 - 121 2018年05月

Purpose: To determine whether the macula is displaced after vitrectomy with internal limiting membrane (ILM) peeling in eyes with an idiopathic macular hole. Design: A retrospective, observational case series. Methods: Optical coherence tomography angiography was used to obtain 3 mm × 3 mm en face images before and 2, 4, and 8 weeks after the vitrectomy with ILM peeling for 20 eyes of 20 patients with an idiopathic macular hole. The displacements of easily identifiable retinal vessel bifurcations were measured relative to the fovea and the optic disc. Results: The distance between the optic disc and vessel bifurcations was significantly shorter in all 4 quadrants throughout the postoperative period (P < .001). This distance was significantly greater in the temporal quadrant (P < .001). The distance of the bifurcations was significantly correlated with the preoperative distance from the optic disc (r = −0.579, P < .001). A significantly greater downward displacement was observed in the superior quadrant (P < .001). The change in the angle of bifurcations was significantly correlated with the preoperative angle to the optic disc (r = −0.632, P < .001). The change in the distance in the inner region was significantly greater than that in the outer region in all quadrants. A significant reduction was observed in the mean foveal avascular zone area during the follow-up period. Conclusions: The retina in the macular region was displaced nasally, probably owing to movement of the retina toward the optic disc because of a contraction after the ILM removal. There is also a possibility of a rotation downward by buoyancy from gas tamponade, and centripetal contraction during the process of hole closure.

DOI CiNii Research

On-ground calibration of the Hitomi Hard X-ray Telescopes

Mori H.

Journal of Astronomical Telescopes, Instruments, and Systems ( Journal of Astronomical Telescopes, Instruments, and Systems ) 4 ( 1 ) 2018年01月

DOI

Multiple Sub–Internal Limiting Membrane Hemorrhages With Double Ring Sign in Eyes With Valsalva Retinopathy

Iwase T.

Retina ( Retina ) 38 ( 1 ) E1 - E2 2018年01月

DOI

内科的治療により網膜動脈塞栓因子の消失を認めたコレステロール結晶塞栓症の一例

波多野岳志, 岩瀬剛, 後藤健介

眼科臨床紀要 ( 東京 : 眼科臨床紀要会 ) 11 ( 8 ) 593 - 595 2018年