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The Presence or Absence of Household Members is a Factor that Influences Treatment Decisions in Patients with Pancreatic Cancer
Sato Yuki, Takahashi Kenichi, Aokawa Masaki, Minami Shinichiro, Chiba Mitsuru, Sato Wataru, Goto Takashi, Iijima Katsunori
Internal Medicine ( 一般社団法人 日本内科学会 ) advpub ( 0 ) 2025年 [査読有り]
研究論文（学術雑誌） 国内共著
<p><b>Objective </b>Although marital status has been demonstrated to affect patients' decisions to undergo active treatment for pancreatic cancer (PC), the role of other household cohabitants remains uncertain. This study aimed to examine whether the presence or absence of other household cohabitants, apart from spouses, affects the treatment decisions of patients with PC. </p><p><b>Methods and Patients </b>A retrospective analysis of patients diagnosed with PC at the Akita University Hospital between January 2014 and December 2020 was conducted. Information about the patients' backgrounds, including the number of persons residing in their households, was gathered. A multivariate regression analysis was conducted to ascertain the factors associated with patients' decisions to undergo aggressive treatment, such as surgery, chemotherapy, and radiotherapy. </p><p><b>Results </b>A total of 214 patients with histopathologically confirmed PC were enrolled in this study. Those who lived with others were more likely to receive aggressive treatment than those who lived alone (84.9% vs. 54.5%; p<0.01). The multivariate analysis, adjusted for patients' age, performance status, and marital status indicated that the patient's decision to undergo aggressive treatment was found to be positively associated with living with other household members with an odds ratio (95% confidence interval): 4.5 (1.02-19.9), p<0.05. </p><p><b>Conclusion </b>Our findings indicate that the influence of cancer treatment decisions extends beyond that of spouses to encompass other household cohabitation members. By providing comprehensive social and emotional assistance to patients residing in isolation, it is possible to facilitate active treatment and enhance the prognosis for patients with PC. </p>
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Extremely late recurrence of ovarian carcinoma diagnosed by an endoscopic ultrasound-guided fine needle biopsy.
Chiba M, Goto T, Sato W, Shibuya T, Takahashi K, Minami S, Matsuzawa H, Sato Y, Iijima K.
Intern Med 2021年01月 [査読有り]
研究論文（学術雑誌）
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A case of acute liver failure caused by the ingestion of Galerina fasciculata
Mitsuru Chiba, Takashi Goto, Kouichi Miura, Shigetoshi Ohshima, Wataru Sato, Tomomi Shibuya, Takahiro Dohmen, Noboru Watanabe, Masanari Sekine, Suguru Arata, Yuko Sugimoto, Kenichi Takahashi, Shinichiro Minami, Mitsuaki Ishioka, Atsushi Saito, Hisanori Matsuzawa, Hirohide Ohnishi.
Akita Journal of Medicine 42 ( 3-4 ) 157 - 161 2016年03月 [査読有り]
研究論文（学術雑誌） 国内共著
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Acoustic radiation force impulse elastography for the differential diagnosis of liver tumors in patients with liver dysfunction
Mitsuru Chiba, Takashi Goto, Shigetoshi Ohshima, Kouichi Miura,Tomomi Shibuya, Wataru Sato, Takahiro Dohmen, Masanari Sekine, Ryo Kanata, Toshitaka Sakai, Shinichiro Minami, Akashi Fujita, Hirohide Ohnishi
Akita Journal of Medicine 42 ( 1 ) 19 - 27 2015年06月
研究論文（学術雑誌） 国内共著
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Efficacy of combined balloon-occluded retrograde transvenous obliteration and simultaneous endoscopic injection sclerotherapy
Sato W, Kamada K, Goto T, Ohshima S, Miura K, Shibuya T, Dohmen T, Kanata R, Sakai T, Chiba M, Sugimoto Y, Minami S, Ishiyama K, Hashimoto M, Ohnishi H.
Internal Medicine 2014年06月 [査読有り]
研究論文（学術雑誌） 国内共著
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Influence of visceral fat area on pancreatic cancer development：A Multicenter Case-Control Study in Akita Prefecture, Japan.
Aokawa M, Chiba M, Takahasi K, Watanabe K, Iijima K.
Akita J Med. 2025年05月 [査読有り]
研究論文（大学，研究機関紀要） 国内共著
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Sakaki Kotaro, Chiba Mitsuru, Iijima Katsunori, Goto Takashi, Arita Junichi, Tsuda Hidehiko
Internal Medicine ( 一般社団法人 日本内科学会 ) advpub ( 0 ) 679 - 685 2024年
<p>A 59-year-old woman was diagnosed with a pancreatic neuroendocrine tumor (P-NET; Grade 3, Ki67: 25%) with multiple liver and lymph node metastases and started chemotherapy with streptozosin (500 mg/m<sup>2</sup>/day) in combination with lanreotide acetate (120 mg). After six courses of (daily) streptozosin, the patient had progressive disease, as assessed by computed tomography (CT), and peptide receptor radionuclide therapy (PRRT) was started as second-line treatment. As PRRT was remarkably successful and the tumor shrank, surgery was performed to resect the primary pancreatic tumor, liver metastases, and lymph node metastases. CT evaluation performed six months after the surgery showed a complete response. </p>
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Chiba Mitsuru, Aokawa Masaki, Goto Takashi, Sato Wataru, Takahashi Kenichi, Minami Shinichiro, Iijima Katsunori
Journal of Rural Medicine ( 一般社団法人 日本農村医学会 ) 19 ( 1 ) 44 - 48 2023年
<p><b>Objective:</b> Bile duct tumor thrombosis in hepatocellular carcinoma (HCC) is a relatively rare event with a poor prognosis. Furthermore, bile duct tumor thrombus in HCC may be misdiagnosed when only imaging modalities are used. The efficiency of peroral cholangioscopy (POCS) in evaluating bile duct lesions has been reported.</p><p><b>Patients:</b> We present three cases of HCC with bile duct strictures in which POCS was performed as a preoperative evaluation.</p><p><b>Results:</b> In these three cases, diagnosing whether the lesion was a bile duct tumor thrombus on CT and endoscopic retrograde cholangiopancreatography was difficult. We performed POCS in three cases and were able to diagnose the presence of bile duct tumor thrombus of HCC, including differentiation from extrinsic compression of the bile duct.</p><p><b>Conclusion:</b> POCS for HCC with bile duct features is useful for the preoperative diagnosis of bile duct tumor thrombus, especially in cases where the surgical procedure depends on the presence of bile duct tumor thrombus.</p>
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Matsuzawa Hisanori, Goto Takashi, Shibuya Tomomi, Sato Wataru, Chiba Mitsuru, Takahashi Kenichi, Minami Shinichiro, Sato Yuki, Iijima Katsunori
Japanese Journal of Medicine ( 一般社団法人 日本内科学会 ) advpub ( 0 ) 1617 - 1623 2023年
<p>Primary cystic duct carcinoma is a rare tumor. The curative treatment of cystic duct carcinoma is complete surgical resection, for which the evaluation of local extension is important. We herein report two cases of cystic duct carcinoma in which a preoperative examination was performed using per-oral cholangioscopy (POCS). Both patients underwent POCS due to suspicion of cystic duct carcinoma based on imaging findings. A visual analysis and biopsy were performed to evaluate local extension, which led to surgery. These cases suggest that POCS is useful for the preoperative assessment of local extension in advanced cystic duct carcinoma. </p>
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Chiba M.
Internal Medicine ( Internal Medicine ) 60 ( 2 ) 247 - 250 2021年01月
<p>We herein report a case of recurrence of epithelial ovarian carcinoma 41 years after the primary surgery that was diagnosed by an endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB). The differential diagnosis based on the imaging findings was difficult. We performed an EUS-FNB and compared the EUS-FNB specimen to the surgical specimen that had been resected in the primary surgery for ovarian carcinoma 41 years earlier, including immunohistochemical staining. Finally, we made a definitive diagnosis of extremely late recurrence of ovarian carcinoma of the retroperitoneum. An EUS-FNB enables an accurate histological diagnosis by obtaining a sample that is large enough to perform immunohistochemical staining. </p>
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Matsuzawa H.
Internal Medicine ( Internal Medicine ) 59 ( 16 ) 2077 - 2081 2020年
<p>Splenic sarcoidosis is often diagnosed by splenectomy or an ultrasound-guided splenic biopsy. However, splenectomy is invasive and costly, and a percutaneous biopsy is sometimes difficult. We herein report a case of splenic sarcoidosis diagnosed with endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA). A 71-year-old man was referred to our hospital for abnormal shadows on a chest roentgenogram. Computed tomography showed multiple lesions in the spleen and pulmonary consolidations. Bronchoscopy revealed no definitive diagnosis. We therefore performed EUS-FNA for a splenic lesion that led to the diagnosis. This case suggests that EUS-FNA is useful in confirming the diagnosis of sarcoidosis with suspected splenic lesions. </p>
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当院における休日ERCPの変容と現状
千葉 充，青川 真樹，後藤 隆，佐藤 亘，高橋 健一，南 慎一郎，佐藤 裕貴， 飯島 克
第171回日本消化器内視鏡学会東北支部例会 2024年02月 - 2024年02月
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当科における膵癌に対する初回胆道ドレナージの現状と成績
千葉 充，高橋 健一，佐藤 裕貴，青川 真樹，飯島 克則
第59回日本胆道学会学術集会 2023年09月 - 2023年09月
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膵癌患者の治療選択に関連する背景因子の検討
千葉 充，青川 真樹，佐藤 裕貴，高橋 健一，南 慎一郎， 佐藤 亘，後藤 隆， 飯島 克則
日本消化器病学会東北支部第215回例会 2023年07月 - 2023年07月
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当院における消化管粘膜下腫瘍に対するFNB針の使用成績
千葉 充，青川 真樹，後藤 隆，佐藤 亘，高橋 健一，南 慎一郎，佐藤 裕貴， 飯島 克
第169回日本消化器内視鏡学会東北支部例会 2023年02月 - 2023年02月
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The effect of family members living together on treatment decisions for pancreatic cancer
Kenichi Takahashi, Mitsuru Chiba, Hisanori Matsuzawa
The 26th meeting of international association of pancreatology 2022年07月 - 2022年07月