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Affiliation |
Graduate School of Medicine Doctorial Course in Medicine Oncoregulatory Medicine Department of Gastroenterology and Neurology |
IIJIMA Katsunori
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Graduating School 【 display / non-display 】
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-1992.03
Tohoku University Faculty of Medicine Graduated
Graduate School 【 display / non-display 】
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-1999.03
Tohoku University Graduate School, Division of Medicine Doctor's Course Completed
Campus Career 【 display / non-display 】
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2015.08-Now
Akita University Graduate School of Medicine Doctorial Course in Medicine Oncoregulatory Medicine Professor
Research Achievements 【 display / non-display 】
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Dietary nitrate generates potentially mutagenic concentrations of nitric oxide at the gastroesophageal junction.
Iijima K, Henry E, Moriya A, Wirz A, Kelman AW, McColl KE.
Gastroenterology 2002.01 [Refereed]
Research paper (journal) Domestic Co-author
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Changes in gastric acid secretion assayed by endoscopic gastrin test before and after Helicobacter pylori eradication.
Iijima K, Ohara S, Sekine H, Koike T, Kato K, Asaki S, Shimosegawa T, Toyota T.
Gut 2000.01
Research paper (journal) Domestic Co-author
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A new endoscopic method of gastric acid secretory testing.
Iijima K, Ohara S, Sekine H, Koike T, Kubota Y, Kato K, Asaki S, Toyota T.
Am J Gastroenterol. 1999.11 [Refereed]
Research paper (journal) Domestic Co-author
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Gender differences in esophageal mucosal injury in a reflux esophagitis model of rats.
Masaka T, Iijima K, Endo H, Asanuma K, Ara N, Ishiyama F, Asano N, Koike T, Imatani A, Shimosegawa T.
Gut 2013.01 [Refereed]
Research paper (journal) Domestic Co-author
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Diffusion of cytotoxic concentrations of nitric oxide generated luminally at the gatro-esophageal junction of rats
25. Asanuma K, Iijima K, Sugata H, Ohara S, Shimosegawa T, Yoshimura T.
Gut 2005.01 [Refereed]
Research paper (journal) Domestic Co-author
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RECENT TRENDS OF GASTROESOPHAGEAL REFLUX DISEASE AND ESOPHAGEAL ADENOCARCINOMA IN JAPAN
IIJIMA Katsunori
GASTROENTEROLOGICAL ENDOSCOPY ( Japan Gastroenterological Endoscopy Society ) 63 ( 8 ) 1465 - 1474 2021.08
<p>In Western countries, the incidence of esophageal adenocarcinoma began to increase in the 1960s to 1970s, and sharply increased in the 1980s to 2000s. In Japan, a series of recent reports indicated that the incidence of esophageal adenocarcinoma began to increase in the 2000s to 2010s, 40 to 50 years behind the situation in Western countries. The time lag in the onset of esophageal adenocarcinoma between Western countries and Japan may be related to the difference in the time when the <i>Helicobacter pylori</i> (<i>H. pylori</i>) infection rate began to decline. Whether or not a rapid increase in esophageal adenocarcinoma cases that occurred in Western countries can also occur in Japan in the future is of great concern. At present, such a rapid increase in esophageal adenocarcinoma cases is unlikely to occur in Japan due to the lower risk of conditions predisposing to gastroesophageal reflux disease (GERD) such as higher gastric acid secretion level and obesity rate in Japanese, and due to ethnic differences in susceptibility to esophageal adenocarcinoma. However, the incidence of esophageal adenocarcinoma in Japan is expected to gradually increase due to the further decrease in the <i>H. pylori</i> infection rate.</p>
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Remaining Clinical Issues on <i>H. Pylori</i> Infection
Iijima Katsunori
Nihon Naika Gakkai Zasshi ( The Japanese Society of Internal Medicine ) 110 ( 1 ) 7 - 9 2021.01
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Shimodaira Yosuke, Watanabe Kenta, Iijima Katsunori
The Tohoku Journal of Experimental Medicine ( Tohoku University Medical Press ) 255 ( 1 ) 33 - 39 2021
<p>The onset age of ulcerative colitis has been increasing in several countries. Furthermore, the number of elderly patients with ulcerative colitis has been increasing in an aging society. We investigated the incidence of ulcerative colitis patients in Japan using a large-scale health insurance claims database to survey the ulcerative colitis incidence ratio and the clinical characteristics in late-onset ulcerative colitis patients. Newly diagnosed 2,791 ulcerative colitis between 2015 and 2018 was investigated. Medical treatment within 12 months of diagnosis was analyzed among 0-19, 20-39, 40-59 and 60-75 age groups. The mean age at diagnosis was 40.3 years (SD: 12.9), and the incidence ratio peaked in the 40's. Most of patients received 5-aminocylitic acid (91.7%), a subset of patients received prednisolone (20.1%), and a small number of patients took immunomodulator (6.8%), cytapheresis (3.3%), anti-TNF<i>α</i> therapy (4.3%), and colectomy (1.0%) within 12 months after diagnosis. All treatments except colectomy were most frequent in the 0-19 age group; however, colectomy was most frequent in 60-75 age group.<b> </b>The clinical course of ulcerative colitis that developed in adults did not differ significantly in terms of medical treatment within 12 months from the onset; meanwhile, the surgery rate was high in elderly patients. It is necessary to pay close attention to future trends regarding the aging of the onset age and the treatment, especially for late-onset ulcerative colitis patients.</p>
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Recent advance in medical treatment for GERD
IIJIMA Katsunori
Nippon Shokakibyo Gakkai Zasshi ( The Japanese Society of Gastroenterology ) 114 ( 10 ) 1790 - 1796 2017
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IV. How Does the Etiology of Peptic Ulcers Change in Post-<i>Helicobacter pylori</i> Era?
Iijima Katsunori
Nihon Naika Gakkai Zasshi ( The Japanese Society of Internal Medicine ) 106 ( 1 ) 33 - 38 2017
◆Original paper【 display / non-display 】
◆Other【 display / non-display 】
Grant-in-Aid for Scientific Research 【 display / non-display 】
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Grant-in-Aid for Scientific Research(C)
Project Year： 2018.03 - 2020.03
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Grant-in-Aid for Scientific Research(C)
Project Year： 2014.03 - 2016.03
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Grant-in-Aid for Scientific Research(C)
Project Year： 2009.03 - 2012.03
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Grant-in-Aid for Scientific Research(C)
Project Year： 2007.03 - 2008.03
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Grant-in-Aid for Young Scientists(B)
Project Year： 2005.03 - 2006.03