Research Achievements - Original paper -

Properties and crystal structure of methylene- tetrahydrofolate reductase from Thermus thermophilus HB8

Igari S., Ohtaki A., Yamanaka Y., Sato Y., Yohda M., Odaka M., Noguchi K., and Yamada K.

PLoS One   6 ( 8 ) e23716   2011.08  [Refereed]

Research paper (journal)   Domestic Co-author

Structure and characterization of amidase from Rhodococcus sp.N-771: Insight into the molecular mechanism of substrate recognition

Ohtaki A., Murata K., Sato Y., Noguchi K., Miyatake H., Dohmae N., Yamada K., Yohda M., and Odaka M.

Biochimica et Biophysica Acta   1804 ( 1 ) 184 - 192   2010.01  [Refereed]

Research paper (journal)   Domestic Co-author

Kinetic and structural studies on roles of the serine ligand and a strictly conserved tyrosine residue in nitrile hydratase

Yamanaka Y., Hashimoto K., Ohtaki A., Noguchi K., Yohda M., and Odaka M.

Journal of Biological Inorganic Chemistry   15 ( 5 ) 655 - 665   2010.01  [Refereed]

Research paper (journal)   Domestic Co-author

Crystal structures of the lumazine protein from Photobacterium kishitanii in complexes with the authentic chromophore, 6,7-dimethyl-8-(1'-D-ribityl) lumazine and its analogues, riboflavin and FMN, at high resolution

Sato Y., Shimizu S., Ohtaki A., Noguchi K., Miyatake M., Dohmae N., Sasaki S., Odaka M., and Yohda M.

Journal of Bacteriology   192 ( 1 ) 127 - 133   2010.01  [Refereed]

Research paper (journal)   Domestic Co-author

Structural basis for catalytic activation of thiocyanate hydrolase involving metal-ligated cysteine modification

Arakawa T., Kawano Y., Katayama Y., Nakayama H., Dohmae N., Yohda M., and Odaka M.

Journal of American Chemical Society   131 ( 41 ) 14838 - 14843   2009.10  [Refereed]

Research paper (journal)   Domestic Co-author

Catalytic mechanism of nitrile hydratase proposed by time-resolved X-ray crystallography using a novel substrate, tert-butylisonitrile

Hashimoto K., Suzuki H., Taniguchi K., Noguchi T., Yohda M., and Odaka M.

Journal of Biological Chemistry   283 ( 52 ) 36617 - 36623   2008.12  [Refereed]

Research paper (journal)   Domestic Co-author

Novel catalytic activity of nitrile hydratase from Rhodococcus sp. N771

Taniguchi K., Murata K., Murakami Y., Takahashi S., Nakamura T., Hashimoto K., Koshino K., Dohmae N., Yohda M., Hirose T., Maeda M., and Odaka M.

Journal of Bioscence and Bioengineering   106 ( 2 ) 174 - 179   2008.08  [Refereed]

Research paper (journal)   Domestic Co-author

Structure of aspartate racemase complexed with a dual substrate analogue, citric acid, and implications for the reaction mechanism

Ohtaki A., Nakano Y., Iizuka R., Arakawa T., Yamada K., Odaka M., and Yohda M.

Proteins   70 ( 4 ) 1167 - 1174   2008.03  [Refereed]

Research paper (journal)   Domestic Co-author

Structure and molecular dynamics simulation of archaeal prefoldin: the molecular mechanism for binding and recognition of nonnative substrate proteins

Ohtaki A., Kida H., Miyata Y., Ide N., Yonezawa A., Arakawa T., Iizuka R., Noguchi K., Kita A., Odaka M., Miki K., and Yohda M.

Journal of Molecular Biology   376 ( 4 ) 1130 - 1141   2008.02  [Refereed]

Research paper (journal)   Domestic Co-author

Structure of thiocyanate hydrolase: a new nitrile hydratase family protein with a novel five-coordinate cobalt(III) center

Arakawa T., Kawano Y., Kataoka S., Katayama Y., Kamiya N., Yohda M., and Odaka M.

Journal of Molecular Biology   366 ( 5 ) 1497 - 1509   2007.03  [Refereed]

Research paper (journal)   Domestic Co-author

Functional expression of thiocyanate hydrolase is promoted by its activator protein, P15K

Kataoka S., Arakawa T., Hori S., Katayama Y., Hara Y., Matsushita Y., Nakayama H., Yohda M., Nyunoya H., Dohmae N., Maeda M., and Odaka M.

FEBS Letters   580 ( 19 ) 4667 - 4672   2006.08  [Refereed]

Research paper (journal)   Domestic Co-author

Mutational study on αGln90 of Fe-type nitrile hydratase from Rhodococcus sp. N771

Takarada H., Kawano Y., Hashimoto K., Nakayama H., Ueda S., Yohda M., Kamiya N., Dohmae N., Maeda M., and Odaka M.

Biosciece, Biotechnology and Biochemistry   70 ( 4 ) 881 - 890   2006.04  [Refereed]

Research paper (journal)   Domestic Co-author

Thiocyanate hydrolase is a cobalt-　containing metalloenzyme with a cysteine sulfinic acid ligand

Katayama Y., Hashimoto K., Nakayama N., Mino H., Nojiri M., Ono T., Nyunoya H., Yohda Y., Takio K., and Odaka M.

Journal of American Chemical Society   128 ( 3 ) 728 - 729   2006.01  [Refereed]

Research paper (journal)   Domestic Co-author

S K-edge XAS and DFT calculations on nitrile hydratase: Geometric and electronic structure of the non-heme iron active site.

Dey, A., Chow, M., Taniguchi, K., Lugo-Mas, P., Davin, S. D., Maeda, M., Kovacs, J. A., Odaka M., Hedman, B., Hodgson, K. O., and Solomon, E. I.

Journal of American Chemical Society   128 ( 2 ) 533 - 541   2006.01  [Refereed]

Research paper (journal)   Domestic Co-author

Trigger factor from Thermus thermophilus is a Zn2+-dependent chaperone

Suno, R., Taguchi, H., Masui, R., Odaka M., and Yoshida, M.

Journal of Biological Chemistry   279 ( 8 ) 6380 - 6384   2004.02  [Refereed]

Research paper (journal)   Domestic Co-author

ATP binding is critical for the conformational change from an open to closed state in archaeal group II chaperoni

Iizuka R., Yoshida M., Shomura Y., Miki K., Maruyama T., Odaka M., and Yohda M.

Journal of Biological Chemistry   278 ( 45 ) 44959 - 44965   2003.11  [Refereed]

Research paper (journal)   Domestic Co-author

Protonation structures of Cys-sulfinic and Cys-sulfenic acids in the photosensitive nitrile hydratase revealed by Fourier Transform Infrared Spectroscopy

Noguchi T., Nojiri M., Takei K., Odaka M., and Kamiya N.

Biochemistry   42 ( 40 ) 11642 - 11650   2003.10  [Refereed]

Research paper (journal)   Domestic Co-author

Motif CXCC in nitrile hydratase activator is critical for NHase biogenesis in vivo

Lu J., Zheng Y. J., Yamagishi H., Odaka M., Tsujimura M., Maeda M., and Endo I.

FEBS Letters   553 ( 3 ) 391 - 396   2003.10  [Refereed]

Research paper (journal)   Domestic Co-author

A novel inhibitor for Fe-type nitrile hydratase: 2-cyano-2-propyl hydroperoxide

Tsujimura M., Odaka M., Nakayama H., Dohmae N., Koshino H., Asami T., Takio, K. Yoshida S., Maeda M., and Endo I.

Journal of American Chemical Society   125 ( 38 ) 11532 - 11538   2003.09  [Refereed]

Research paper (journal)   Domestic Co-author

Fe-type nitrile hydratase

Endo, I. Nojiri, M., Tsujimura, M., Nakasako, M., Nagashima, S., Yohda, M. and Odaka M.

Journal of Inorganic Biochemistry   83 ( 4 ) 247 - 253   2001.02  [Refereed]  [Invited]

Research paper (journal)   Domestic Co-author