FUJIYAMA Nobuhiro

写真a

Affiliation

Future Cooperative Research Organization Clinical Research Promotion and Support Office 

Research Interests 【 display / non-display

  • 薬物動態学

  • 移植免疫学

Graduating School 【 display / non-display

  • 1998.04
    -
    2002.03

    Hokuriku University   Faculty of Pharmaceutical Science   Graduated

Graduate School 【 display / non-display

  • 2004.04
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    2007.03

    Chiba University    Doctor's Course  Completed

Campus Career 【 display / non-display

  • 2025.06
    -
    Now

    Akita University   Future Cooperative Research Organization Clinical Research Promotion and Support Office   Professor  

  • 2025.04
    -
    2025.05

    Akita University   Future Cooperative Research Organization Clinical Research Promotion and Support Office   Associate Professor  

  • 2024.04
    -
    2025.03

    Akita University   Hospital   Pharmaceutical Management Center   Associate Professor  

  • 2022.04
    -
    2024.03

    Akita University   Hospital   Pharmaceutical Management Center   Lecturer  

  • 2016.04
    -
    2022.03

    Akita University   Hospital   Pharmaceutical Management Center   Assistant Professor  

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Research Achievements 【 display / non-display

    ◆Original paper【 display / non-display

  • Impact of persistent preformed and de novo donor-specific antibodies detected at 1 year after kidney transplantation on long-term graft survival in Japan: a retrospective study.

    Fujiyama N, Satoh S, Saito M, Numakura K, Inoue T, Yamamoto R, Saito T, Kanda S, Narita S, Mitobe Y, Habuchi T.

    Clinical and experimental nephrology   23 ( 12 ) 1398 - 1406   2019.09  [Refereed]

    Research paper (journal)   Domestic Co-author

    DOI

  • Association of immunosuppressive agents and cytomegalovirus infection with de novo donor-specific antibody development within 1 year after renal transplantation.

    Fujiyama N, Satoh S, Saito M, Numakura K, Inoue T, Yamamoto R, Saito T, Nara T, Kanda S, Narita S, Kagaya H, Miura M, Habuchi T.

    International immunopharmacology   76   105881   2019.09  [Refereed]

    Research paper (journal)   Domestic Co-author

    DOI

  • Contribution of UGT1A1 genetic polymorphisms related to axitinib pharmacokinetics to safety and efficacy in patients with renal cell carcinoma.

    Igarashi R, Inoue T, Fujiyama N, Tsuchiya N, Numakura K, Kagaya H, Saito M, Narita S, Satoh S, Niioka T, Miura M, Habuchi T.

    Medical oncology   35 ( 4 ) 51   2018.03  [Refereed]

    Research paper (journal)   Domestic Co-author

    DOI

  • Clinical implications of pharmacokinetics of sunitinib malate and N-desethyl-sunitinib plasma concentrations for treatment outcome in metastatic renal cell carcinoma patients.

    Numakura K, Fujiyama N, Takahashi M, Igarashi R, Tsuruta H, Maeno A, Huang M, Saito M, Narita S, Inoue T, Satoh S, Tsuchiya N, Niioka T, Miura M, Habuchi T.

    Oncotarget   9 ( 38 ) 25277 - 25284   2018.03  [Refereed]

    Research paper (journal)   Domestic Co-author

    DOI

  • ◆Other【 display / non-display

  • Current Status and Challenges of Chronic Kidney Disease Stickers

    Hayakawa Kenji, Kobayashi Yutaka, Kondo Yuki, Isono Tetsuichiro, Inoue Akio, Tsushita Haruka, Fujiyama Nobuhiro, Masuda Nobutoshi, Morizumi Makoto, Yahaba Masayuki, Yamamoto Kazuhiro, Yamamoto Takehito, Urata Motoki

    The Japanese Journal of Nephrology and Pharmacotherapy ( The Japanese Society of Nephrology and Pharmacotherapy )  14 ( 2 ) 171 - 184   2025

    <p>Appropriate prescription review based on kidney function is essential to ensure safe and effective pharmacotherapy. As a simple tool to convey kidney function, the chronic kidney disease (CKD) sticker has been utilized in clinical practice. In a survey conducted by the CKD Sticker Promotion Working Group of the Japanese society of Nephrology and pharmacotherapy, CKD stickers were identified in 62 regions. The scale of implementation varied widely, ranging from prefecture-wide programs to initiatives at individual facilities. A variety of organizations—including local governments, medical associations, and pharmaceutical associations—were involved in their implementation, suggesting that CKD stickers serve not merely as a tool but as part of an organized program.</p><p>In many regions, the primary purpose of CKD stickers was to promote appropriate use of medications by pharmacists, but some areas also used them to facilitate information sharing with primary care physicians or to encourage behavioral changes in patients. The thresholds for estimated glomerular filtration rate (eGFR) at which the stickers were applied appeared to be set according to the objectives of each region, such as early intervention and efficient allocation of medical resources. Both phased replacement formats and versions requiring manual entry of eGFR values were observed. Physicians and pharmacists were the primary professionals responsible for applying the stickers, while in some areas, nurses, public health nurses, dentists, and local government staff were also involved. Certain regions limited sticker application to nephrologists or hospital pharmacists to ensure accuracy, while others later broadened the range of eligible professionals to promote wider adoption. From a design perspective, many regions customized the information displayed on the sticker according to the intended audience, and some even included direct messages to CKD patients.</p><p>Challenges identified included limited spread, leading to uneven application within regions, and the coexistence of multiple types of CKD stickers within the same or neighboring areas. Early-adopter regions reported an increase in prescription queries from pharmacist to physician prompted by CKD stickers and a decrease in hospitalizations due to drug-induced kidney injury. However, there have been no reports of hard endpoints, such as reductions in dialysis initiation or improvements in eGFR slope, indicating the need for future outcome-based studies.</p>

    DOI CiNii Research

  • Method for Distinguishing Identical and Non-Identical Pills in Unit-Dose Packages

    Tatsumi Shuei, Zou Min, Sasaki Katsuya, Kagaya Hideaki, Fujiyama Nobuhiro, Kageyama Yoichi

    Proceedings of IIAE Annual Conference ( The Institute of Industrial Applications Engineers )  2024 ( 0 ) 69 - 70   2024

    DOI CiNii Research

  • Automatic Classification of Colored Pills in ODP-based Machine Learning

    Tatsumi Shuei, Zou Min, Sasaki Katsuya, Kagaya Hideaki, Fujiyama Nobuhiro, Kageyama Yoichi

    Proceedings of IIAE Annual Conference ( The Institute of Industrial Applications Engineers )  2023 ( 0 ) 17 - 18   2023

    DOI CiNii Research