Details of a Researcher

KUME YU

写真a

Affiliation	Doctorial Course in Health Sciences Occupational Therapy
Date of Birth	1983
Laboratory Phone number	+81-18-884-6556
Laboratory Fax number	+81-18-884-6556
Mail Address

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Research Interests 【 display / non-display 】

Research regarding circadian rest-activity rhythm in the elderly
フレイル予防
ウェアラブル技術
Intervention research related to the dementia prevention

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Graduating School 【 display / non-display 】

2003.04

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2007.03

Akita University Faculty of Medicine Department of Occupational Therapy, Health sciences Graduated

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Graduate School 【 display / non-display 】

2013.04

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2016.03

Akita University Graduate School, Division of Medicine Faculty of Health Sciences Doctor's Degree Program Completed
2007.04

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2009.03

Akita University Graduate School, Division of Medicine Health Sciences Master's Course Completed

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Degree 【 display / non-display 】

Akita University - Doctor (Health Sciences)
Akita University - Master (Health of Sciences)
Akita University - Bachelor (Occupational Therapy)

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Campus Career 【 display / non-display 】

2022.04

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Now

Akita University Doctorial Course in Health Sciences Occupational Therapy Professor
2020.04

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2022.03

Akita University Doctorial Course in Health Sciences Occupational Therapy Lecturer
2012.04

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2020.03

Akita University Graduate School of Medicine Doctorial Course in Health Sciences Occupational Therapy Assistant Professor

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Academic Society Affiliations 【 display / non-display 】

2024.09

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Now

Japan

Japanese Psychogeriatric Society
2023.04

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Now

Japan

Akita Society for Public Health
2023.01

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Now

Japan

Sigma Xi, The Scientific Research Honor Society
2021.07

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Now

Japan

The Japanese Geriatric Therapy Society
2021.03

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Now

Switzerland

Journal of Clinical Medicine(JCM)

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Research Areas 【 display / non-display 】

Life Science / Rehabilitation science / Rehabilitation Science/Welfare engineering

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Qualification acquired 【 display / non-display 】

Occupational Therapist

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Thesis for a degree 【 display / non-display 】

Spatial compatibility and affordance compatibility in patients with chronic schizophrenia

Yu Kume, Fumiyasu Sato, Yuya hiraoka, Shingo Suzuki, Yoshitsugu Niyama.

Asian Journal of Psychiatry 2016.03

Domestic Co-author

DOI
Effects of differences in activity goal setting on self-efficary

Bulletin of Graduate School of Health Sciences Akita University 19 ( 1 ) 47 - 56 2009.03

Single author

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Research Achievements 【 display / non-display 】

◆Original paper【 display / non-display 】

Predicting Social Frailty in Older Adults Using Fitbit-Derived Circadian and Heart Rate Biomarkers: Cross-Sectional Study

Hiroki Maekawa, Yu Kume

JMIR formative research ( JMIR publication ) 9 e71393 2025.07 [Refereed]

Research paper (journal) Domestic Co-author

BACKGROUND: Social frailty poses a potential risk even for relatively healthy older adults, necessitating development of early detection and prevention strategies. Recently, consumer-grade wearable devices have attracted attention due to their ability to continuously collect physiological and activity-related data. These data can potentially be used to calculate digital biomarkers for screening social frailty in older adults. OBJECTIVE: The objective of this study was to explore digital biomarkers associated with social frailty using sensor data recorded via Fitbit devices and evaluate their relationship with health outcomes in older adults. METHODS: This cross-sectional study was conducted in 102 community-dwelling older adults. Participants attending frailty prevention programs wore devices from the Fitbit Inspire series on their nondominant wrist for at least 7 consecutive days, during which step count and heart rate data were collected. Standardized questionnaires were used to assess physical functions, cognitive functions, and social frailty, and based on the scores, the participants were categorized into 3 groups: robust, social prefrailty, and social frailty. The sensor data were analyzed to calculate nonparametric and extended cosinor rhythm metrics, along with heart rate-related metrics. RESULTS: The final sample included 86 participants who were categorized as robust (n=28, 33%), social prefrailty (n=39, 45%), and social frailty (n=19, 22%). The mean age of the participants was 77.14 (SD 5.70) years, and 91% (78/86) were women. Multinomial logistic regression analysis revealed that a step-based rhythm metric (intradaily coefficient of variation) was significantly associated with social frailty (odds ratio 1.05, 95% CI 1.01-1.11; P=.01). The heart rate metrics, including the delta resting heart rate and time of transition from rest to activity, showed significant associations with both social prefrailty (odds ratio 0.82, 95% CI 0.68-0.99; P=.04) and social frailty (odds ratio 0.69, 95% CI 0.50-0.95; P=.01). Specifically, delta resting heart rate, defined as the difference between the overall average heart rate and resting heart rate, exhibited significant negative associations with social prefrailty (odds ratio 0.82, 95% CI 0.68-0.97; P=.02) and social frailty (odds ratio 0.74, 95% CI 0.58-0.94; P=.02). Furthermore, analysis using a linear regression model revealed a significant association between the intradaily coefficient of variation and the word list memory score, a measure of cognitive decline (beta=-0.04; P=.02). CONCLUSIONS: This study identified associations between novel rhythm and heart rate metrics calculated from the step count and heart rate recorded by Fitbit devices and social frailty. These findings suggest that consumer-grade wearable devices, which are low cost and accessible, hold promise as tools for evaluating social frailty and its risk factors through enabling the calculation of digital biomarkers. Future research should include larger sample sizes and focus on the clinical applications of these findings.

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Effects of Pole‐Assisted Multicomponent Exercise on Preventing Frailty Among Older Adults in Japan: A Quasi‐Experimental Study

Ayuto Kodama, Yu Kume, Emiko Otake, Mei Fujimoto, Hiromitsu Todo, Nanako Sasaki, Hiroyuki Kodama, Hidetaka Ota

Psychogeriatrics ( Wiley ) 25 ( 5 ) e70067 2025.07 [Refereed]

Research paper (journal) Domestic Co-author

Background: Frailty is a multidimensional geriatric syndrome characterised by reduced physiological reserves. Multidomain interventions combining physical and cognitive activities show promise in delaying frailty and cognitive decline. However, existing programs often face high dropout rates due to joint discomfort and balance concerns among older adults. This study aimed to evaluate the impact of a pole-assisted multicomponent exercise program on physical and cognitive function in community-dwelling older adults. Method: Participants were cluster-randomised into a control group (standard multicomponent exercises) or an intervention group (pole-assisted multicomponent exercises). Both groups participated in biweekly 90-min sessions for 3 months, incorporating stretching, muscle strengthening, aerobic exercises, and cognitive training. Outcomes included physical measures (grip strength; GS, usual walking speed; UWS), cognitive measures (word recognition memory; WM, Trail Making Test A&B, Symbol Digit Substitution Task; SDST), and frailty assessments based on the Fried frailty index. Analyses utilized paired t-test and, with interaction effects evaluated through two-way analyses. Result: Significant improvements were observed within the intervention group for GS, UWS, WM (p < 0.05), and SDST (p < 0.01). The control group demonstrated significant improvements only in WM (p < 0.05). Both groups showed significant reductions in frailty status post-intervention. Importantly, a significant interaction effect was noted for UWS, highlighting superior outcomes in the pole-assisted exercise group. Time effects were significant for UWS, WM, and SDST, indicating general improvements over the intervention period. Conclusion: Integrating pole-assisted intervention into multicomponent exercise regimens effectively enhanced physical performance, reduced frailty, and improved cognitive functions, particularly word memory and information processing capability in community-dwelling older adults. This approach offers practical, scalable solutions suitable for broad implementation in public health settings to mitigate frailty and cognitive decline in aging populations.

DOI DOI2

Characteristics of the Rest and Activity Patterns in Patients With Mild to Moderate Parkinson's Syndrome

Kaori Ono, Yu Kume

Psychogeriatrics ( Wiley ) 25 e70047 2025.05 [Refereed]

Research paper (journal) Domestic Co-author

ABSTRACT Background Few studies have examined the characteristics of the decline in physical activity levels in Parkinson's disease (PD) patients from the perspective of a 24-h behavioural profile, including sleep. Objective To identify factors related to the rest and activity patterns in PD patients by assessing the Rest-Activity Rhythm. Methods The participants were 20 patients with Parkinson's syndrome (PS group) and 20 healthy elderly community residents (control group). The nonparametric rest-activity rhythm parameters were measured by a wristwatch-type activity monitor worn by the study subjects on the non-dominant hand continuously for at least 5 days. To assess the specific symptoms of PS in the patients, the scores on the Movement Disorder Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS) were collected from the medical records. Results In the PS group, a negative correlation was found between the relative amplitude and score for part I of the MDS-UPDRS, that is, non-motor symptoms (r = −0.51, p < 0.05). Additionally, binomial logistic regression analysis revealed two regression models, with Model I showing a significant association with the highest physical activity level over the 24-h profile (odds ratio, 0.96; 95% confidence interval [95% CI], 0.94–0.99; p = 0.002) and Model II showing a significant association with a fragmented rhythm (odds ratio, 1.04; 95% CI, 1.01–1.07; p = 0.004). Conclusion These results suggest that rehabilitation of PD patients should include increasing their physical activity levels while minimising intermittency of the rest and activity patterns, and that attention should be paid to non-motor symptoms in addition to motor symptoms.

DOI

Improvement of social frailty is associated with stability of nonparametric characteristics of the rest-activity rhythm and improvement of the usual walking ability in the elderly

Yu Kume, Ayuto Kodama, Sayaka Arai, Makiko Nagaoka, Akiko Sato, Akira Saito, Hidetaka Ota, Hideaki Ando

Chronobiology International ( Taylor & Francis Group ) 2024.08 [Refereed]

Research paper (journal) Domestic Co-author

Our study, conducted between April 2022 and January 2024, was aimed at clarifying components of the rest-activity rhythm (RAR) involved in improvement of social frailty state before or after a 3-month multi-component exercise intervention in the elderly. Participants were recruited from the general population in Akita prefecture, Japan. We administered a four-item social frailty screening questionnaire to classify the severity of social frailty in each participant before and after the 3-month intervention. The RAR parameters were measured on an Actiwatch Spectrum Plus device worn by the subjects for 7 continuous days. As the final sample, 65 participants classified into the improved/maintained group (n = 36) or the deteriorated group (n = 29) according to the change in the social frailty classification after the intervention were included in the analysis. The results of a binomial logistic regression analysis showed significantly higher values of interdaily stability (IS) and usual walking speed at the post-test after the intervention. Based on our findings, we propose that stability of the rest-activity rhythm related to synchronization with external stimuli (such as social effect and physical activity) might have clinical impact on improvement of social frailty state in elderly community-dwellers.

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Comparative Analysis of Frailty Risk and Associated Factors: Community-Based vs. Open Recruitment Groups

Tatsunori Shimizu, Ayuto Kodama,Yu Kume, Masahiro Iwakura,Katsuya Iijima, Hidetaka Ota

International journal of environmental research and public health ( MDPI ) 21 ( 5 ) 611 2024.05 [Refereed]

Research paper (journal) Single author

Background: Frailty leads to vulnerability to stress, impaired daily functioning, and an increased need for care. Frailty is considered reversible, and it is crucial to detect the risk of frailty early and investigate factors that may delay its progression. Objectives: To identify tests that can explain frailty risk and compare the situation of local residents with and without frailty support. Methods: Participants were recruited in two ways: through public advertisements in Akita City (open recruitment group) and through invites from frailty supporters in their immediate communities (community-based group). We examined the differences in frailty risk and oral, motor, and social functions between the two groups and identified factors associated with frailty risk in both groups. Results: The community-based group exhibited a lower risk of frailty than the open recruitment group despite having more older members on average. Additionally, the community-based group demonstrated better social functioning than the open-recruitment group. Furthermore, factors such as oral diadochokinesis (ODK), one-leg stand test (OLS), and grip strength (GS) showed significant association with frailty risk. Conclusion: The ODK, OLS, and GS were identified as factors explaining frailty risk, and Frailty Supporters may reduce the risk of frailty.

DOI

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