研究等業績 - 原著論文 - 宮腰 尚久
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Diagnostic accuracy of ultrasonography for occult femoral neck fracture
Tsukamoto H.
Journal of Clinical Orthopaedics and Trauma ( Journal of Clinical Orthopaedics and Trauma ) 36 2023年01月
研究論文（学術雑誌）
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Distal sacral nerve roots severed by a fragility fracture of the sacrum: a case report
Igarashi S.
Journal of Medical Case Reports ( Journal of Medical Case Reports ) 16 ( 1 ) 2022年12月
研究論文（学術雑誌）
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Akagawa M.
Journal of Experimental Orthopaedics ( Journal of Experimental Orthopaedics ) 9 ( 1 ) 2022年12月
研究論文（学術雑誌）
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Emori M.
BMC Musculoskeletal Disorders ( BMC Musculoskeletal Disorders ) 23 ( 1 ) 378 - 378 2022年12月
研究論文（学術雑誌）
BACKGROUND: The aim of the present study was to evaluate the prevalence of non-ossifying fibroma (NOF) and fibrous cortical defect (FCD) in a Japanese pediatric population and the association between the lesion size and pain. METHODS: This retrospective study, conducted across 10 Japanese institutions, included patients aged 5-15 years who had undergone standard antero-posterior and lateral view radiography of the knee. Using these radiographs, we diagnosed the lesion as a NOF or FCD. Patient demographics, including age, sex, the size and location of the NOF, and chief complaint were recorded. The lesion size was determined using radiographs. Student's t-test was used to compare the associations between the lesion size and spontaneous pain. RESULTS: A total of 6222 subjects (3567 boys and 2455 girls) were included in this study. The number of NOF and FCD cases was 143 and 437, respectively, and the prevalence of NOF and FCD was 2.3% and 7.0%, respectively. The average size of NOF and FCD was 22.1 mm (range: 4-102 mm) and 13.2 mm (range: 5-21 mm), respectively. Three patients (2.1%) had pathological fractures due to NOF. Of the 140 NOFs and 437 FCDs, we obtained complaints from the medical records of 126 and 393 patients, respectively. The number of patients with spontaneous pain or other problems with NOF was 68 (54%) and 58 (46%), respectively, that of patients with FCD was 195 (50%) and 198 (50%) patients, respectively. The lesion size was not associated with spontaneous pain in either lesion (p = 0.67 and p = 0.27, respectively). CONCLUSION: The prevalence of NOF and FCD around the knee was lower than that reported in previous studies. The prevalence of NOF increased and that of FCD decreased with advancing age. In both lesions, the lesion size may not be associated with pain.
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Suzuki N.
Medicine (United States) ( Medicine (United States) ) 101 ( 48 ) 2022年12月
研究論文（学術雑誌）
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Miura T.
International Journal of Environmental Research and Public Health ( International Journal of Environmental Research and Public Health ) 19 ( 24 ) 2022年12月
研究論文（学術雑誌）
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特集 PLIF・TLIF-手術手技の原点とエキスパートの工夫 椎間関節全切除して行うPLIFの工夫と留意点
奥山 幸一郎, 木戸 忠人, キリアン フランシス, 千葉 光穂, 阿部 栄二, 宮腰 尚久
脊椎脊髄ジャーナル ( 三輪書店 ) 35 ( 7 ) 471 - 478 2022年12月
研究論文（学術雑誌）
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Shoji R.
Anticancer Research ( Anticancer Research ) 42 ( 11 ) 5357 - 5363 2022年11月
研究論文（学術雑誌）
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Komatsu M.
Journal of Clinical Orthopaedics and Trauma ( Journal of Clinical Orthopaedics and Trauma ) 34 2022年11月
研究論文（学術雑誌）
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Horikawa A.
Medicine (United States) ( Medicine (United States) ) 101 ( 43 ) 2022年10月
研究論文（学術雑誌）
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Hirota R.
Spine ( Spine ) 47 ( 19 ) 1391 - 1398 2022年10月
研究論文（学術雑誌）
STUDY DESIGN: Retrospective analysis of prospectively collected multicenter observational data. OBJECTIVE: The aim was to examine the preoperative factors affecting postoperative satisfaction following posterior lumbar interbody fusion (PLIF) and microendoscopic muscle-preserving interlaminar decompression (ME-MILD) in patients with degenerative lumbar spondylolisthesis (DLS). SUMMARY OF BACKGROUND DATA: The technique involved in DLS surgery may either be decompression alone or decompression-fixation. Poor performance may occur after either of these surgical treatments. The author hypothesized that evaluating the correlation between preoperative quality of life and postoperative performance would aid in determining the optimal procedure. MATERIALS AND METHODS: This study included 138 patients who underwent surgery for 1-level mild DLS. The authors performed PLIF for 79 patients and ME-MILD for 59 patients. When the satisfaction subscale of the Zurich Claudication Questionnaire exceeded 2 points, postoperative satisfaction was considered poor. The clinical characteristics were investigated. Responses to preoperative health-related quality of life questionnaires, such as the Japanese Orthopedic Association Back Pain Evaluation Questionnaire (JOABPEQ), short form-36 health survey (SF-36), and visual analog scale, were compared between the satisfied and unsatisfied groups. RESULTS: In the PLIF group, no endogenous factors influenced postoperative satisfaction. The ME-MILD cohort's satisfied and unsatisfied patients differed significantly in terms of preoperative lumbar spine dysfunction ( P <0.001) items of the JOABPEQ, role physical ( P =0.03), and role emotional ( P =0.03) items of the SF-36. A strong correlation ( r =-0.609 P =0.015) was found between preoperative lumbar spine dysfunction and postoperative satisfaction. CONCLUSIONS: In the ME-MILD group, preoperative lumbar spine function was correlated with postoperative satisfaction. Decompression alone may be ineffective in cases with decreased lumbar spine function prior to surgery. The degree of low back pain on movement should be considered before selecting the surgical method. LEVEL OF EVIDENCE: 3.
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Risk Factors of Early Distant Metastasis after Primary Tumor Treatment in Soft Tissue Sarcoma
Tsuchie H.
In Vivo ( In Vivo ) 36 ( 5 ) 2260 - 2264 2022年09月
研究論文（学術雑誌）
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特集 医工連携と腰痛 新たな筋骨格モデルを用いた脊柱後弯患者における股関節間力,椎間板負荷の解析
三浦 隆徳, 粕川 雄司, 本郷 道生, 宮腰 尚久
脊椎脊髄ジャーナル ( 三輪書店 ) 35 ( 5 ) 303 - 308 2022年09月
研究論文（学術雑誌）
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臨床室 陳旧性の踵骨前方突起骨折に対して骨接合術を施行しスポーツ復帰した1例
浅香 康人, 関 展寿, 加茂 啓志, 木戸 忠人, 奥山 幸一郎, 宮腰 尚久
整形外科 ( 南江堂 ) 73 ( 10 ) 1052 - 1055 2022年09月
研究論文（学術雑誌）
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Miura T.
Medicina (Lithuania) ( Medicina (Lithuania) ) 58 ( 8 ) 1058 - 1058 2022年08月
研究論文（学術雑誌）
Background and Objectives: Adequate initial fixation of the uncemented acetabular component in total hip arthroplasty is necessary to achieve long-term survival. Although screw fixation contributes to improved cup stability, there is currently no consensus on the use of this method. This study aimed to assess the existing randomized controlled trials (RCTs) on the efficacy and safety of cup fixation in total hip arthroplasty without screws. Materials and Methods: We searched the EMBASE, MEDLINE, Cochrane Central Register of Controlled Trials, World Health Organization International Clinical Trials Registry Platform, and ClinicalTrials.gov databases to identify RCTs published before February 2022. Primary outcomes were reoperation, cup migration, and Harris Hip Score. Secondary outcomes were the presence of a radiolucent line in the acetabular region, translation and rotation movement, and polyethylene wear. We conducted meta-analyses using the random-effects models. The revised Cochrane risk-of-bias tool was used to assess the risk of bias for outcomes of interest; the Grading of Recommendations, Assessment, Development, and Evaluation approach was used to summarize the body of evidence. Results: We included six reports from four studies. Total hip arthroplasty without screw fixation to the acetabular cup had little to no effect on reoperation (pooled relative risk, 0.98; 95% confidence interval, 0.14–6.68; I2 = 0%), cup migration (pooled relative risk, 1.72; 95% confidence interval, 0.29–10.33; I2 = 1%), Harris Hip Score (mean difference, 1.19; 95% confidence interval, −1.31–3.70; I2 = 0%), radiolucent line (pooled relative risk, 5.91; 95% confidence interval, 0.32–109.35), translation and rotation of all axes, and polyethylene wear (mean difference, 0.01; 95% confidence interval, −0.01–0.04; I2 = 0%), with very low certainty of evidence on all measures. Conclusions: The efficacy of acetabular cups without screw fixation in total hip arthroplasty remains uncertain, suggesting the need for prudent clinical application. Further large-scale, well-designed studies with low risk of bias are required.
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ACL不全を伴う高度外反膝に対して脛骨後方傾斜を水平化する Double Level Osteotomy（DLO）を施行した１例
渡辺 学, 佐々木 香奈, 齊藤 英知, 湯浅 悠介, 杉村 祐介, 鈴木 哲哉, 千馬 誠悦, 島田 洋一, 宮腰 尚久
東北膝関節研究会会誌 ( 東北膝関節研究会 ) 30 ( 0 ) 21 - 25 2022年07月
研究論文（学術雑誌）
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Earlier appearance of Risser sign on ultrasound versus radiograph in adolescent idiopathic scoliosis
Hongo M.
Journal of Clinical Imaging Science ( Journal of Clinical Imaging Science ) 12 2022年07月
研究論文（学術雑誌）
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Horikawa A.
Journal of Bone and Mineral Metabolism ( Journal of Bone and Mineral Metabolism ) 40 ( 4 ) 670 - 676 2022年07月
研究論文（学術雑誌）
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大腿骨遠位部骨軟骨腫に対して鏡視下腫瘍切除術を行った１例
村田 昇平, 齊藤 英知, 瀬川 豊人, 斉藤 公男, 佐々木 香奈, 佐藤 千恵, 赤川 学, 塚本 泰朗, 高橋 靖博, 三浦 隆徳, 谷 貴行, 蝦名 寿仁, 島田 洋一, 宮腰 尚久
東北膝関節研究会会誌 ( 東北膝関節研究会 ) 30 ( 0 ) 3 - 6 2022年07月
研究論文（学術雑誌）
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特集 足関節周囲外傷の治療 ピロン骨折における軟部組織合併症を回避するためのコツ
野坂 光司, 土江 博幸, 湯浅 悠介, 三田 基樹, 原田 俊太郎, 宮腰 尚久
整形・災害外科 ( 金原出版 ) 65 ( 8 ) 1023 - 1029 2022年07月
研究論文（学術雑誌）
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大腿四頭筋腱断裂に対する修復術の検討 直視下1例と鏡視下2例
浅香 康人, 木村 竜太, 小林 孝, 齊藤 英知, 宮腰 尚久
東日本整形災害外科学会雑誌 ( 東日本整形災害外科学会 ) 34 ( 2 ) 116 - 118 2022年06月
研究論文（学術雑誌）
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Kasukawa Y.
Applied Sciences (Switzerland) ( Applied Sciences (Switzerland) ) 12 ( 9 ) 2022年05月
研究論文（学術雑誌）
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飯田 純平, 島田 洋一, 本郷 道生, 宮腰 尚久
整形外科 ( 南江堂 ) 73 ( 5 ) 438 - 438 2022年05月
研究論文（学術雑誌）
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特集 変形性関節症・変形性脊椎症の保存療法を究める 変形性脊椎症の保存療法-運動療法と装具療法
木村 竜太, 宮腰 尚久, 島田 洋一
総合リハビリテーション ( 株式会社医学書院 ) 50 ( 5 ) 467 - 471 2022年05月
研究論文（学術雑誌）
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Causes and Clinical Outcomes of Patellar Post Impingement
Tomite T.
Arthroplasty Today ( Arthroplasty Today ) 14 48 - 52 2022年04月
研究論文（学術雑誌）
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Vertebral Osteomyelitis and Infective Endocarditis Co-Infection
Morimoto T.
Journal of Clinical Medicine ( Journal of Clinical Medicine ) 11 ( 8 ) 2022年04月
研究論文（学術雑誌）
Many cases of vertebral osteomyelitis (VO) and infective endocarditis (IE) co-infection have been reported, and it has been recognized that attention should be paid to the possibility of both diseases co-existing during diagnosis and treatment. However, the incidence, clinical status, and outcomes of IE in patients with VO remain unclear. For this study, the eligibility criteria for patient recruitment included all cases of VO at the five medical university hospitals. Patients with a history of spinal surgery were excluded from this study. Echocardiography was routinely performed for all patients with VO. IE was diagnosed according to the modified Duke criteria for definite endocarditis. We analyzed demographic data, underlying conditions, clinical features, laboratory data, echocardiography, radiologic images, treatments, and outcomes. VO was diagnosed in 59 patients and IE was diagnosed in seven patients (12%). There were no significant differences in the clinical features, microorganisms, or radiographic status between the VO-IE co-infection and VO-only groups. In this study, using routine echocardiography for VO, the IE prevalence was 12%. The lack of specific clinical features and laboratory findings may hamper the diagnosis of IE. Therefore, clinicians are always required to suspect IE in patients with VO.
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Shoji R.
In vivo (Athens, Greece) ( In vivo (Athens, Greece) ) 36 ( 2 ) 667 - 671 2022年03月
研究論文（学術雑誌）
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特集 成人脊柱変形Up to Date 第4章 治療 成人脊柱変形に対する保存療法-脊柱変形,疼痛への効果
本郷 道生, 宮腰 尚久, 粕川 雄司
脊椎脊髄ジャーナル ( 三輪書店 ) 34 ( 11 ) 736 - 742 2022年03月
研究論文（学術雑誌）
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特集 変形性足関節症の臨床 変形性足関節症に対する遠位脛骨斜め骨切り術
野坂 光司, 齊藤 英知, 木島 泰明, 斉藤 公男, 河野 哲也, 原田 俊太郎, 宮腰 尚久, 島田 洋一
関節外科 基礎と臨床 ( メジカルビュー社 ) 41 ( 1 ) 52 - 57 2022年01月
研究論文（学術雑誌）
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特集 知っておきたい足関節周囲骨折の新展開 高齢者でこそ有用な足関節周囲骨折におけるMATILDA法
野坂 光司, 齊藤 英知, 木島 泰明, 白幡 毅士, 土江 博幸, 斉藤 公男, 河野 哲也, 原田 俊太郎, 宮腰 尚久
臨床整形外科 ( 株式会社医学書院 ) 57 ( 1 ) 43 - 49 2022年01月
研究論文（学術雑誌）
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Chronic atlantoaxial rotatory fixation with neurofibromatosis type I: A case report
Ono Y.
Surgical Neurology International ( Surgical Neurology International ) 13 2022年
研究論文（学術雑誌）
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Abe K.
Journal of Bone and Mineral Metabolism ( Journal of Bone and Mineral Metabolism ) 2022年
研究論文（学術雑誌）
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Aphasia testing (auditory comprehension domain) using a new eye-tracking system in healthy participants
Sakai Risa, Koike Yasuharu, Saito Kimio, Matsunaga Toshiki, Shimada Yoichi, Miyakoshi Naohisa
Japanese Journal of Comprehensive Rehabilitation Science ( 一般社団法人 回復期リハビリテーション病棟協会 ) 13 ( 0 ) 31 - 35 2022年
研究論文（学術雑誌）
<p>Sakai R, Koike Y, Saito K, Matsunaga T, Shimada Y, Miyakoshi N. Aphasia testing (auditory comprehension domain) using a new eye-tracking system in healthy participants. Jpn J Compr Rehabil Sci 2022; 13: 31‒35.</p><p><b>Objective</b>: We administered a conventional pointingmethod test with eye-tracking to evaluate items associated with auditory comprehension and examined the concordance between the obtained results.</p><p><b>Methods</b>: The enrolled participants were 10 healthy volunteers. We performed tests after extracting auditory comprehension items from the SLTA, the WAB, and the Supplementary tests for the SLTA using the eye-tracking system and the pointing method.</p><p><b>Results</b>: The mean test duration was 9 min 51 s ± 1 min 41 s (mean ± SD), and the percentage of correct answers was 100% and in perfect agreement for the pointing method and the eye-tracking system. The mean response time was 0.96 ± 0.36 s for the pointing method and −0.39 ± 0.21 s for the eye-tracking system. Hence, the latter was faster than the former, and examinees completed their responses before listening to the end of the questions.</p><p><b>Conclusion</b>: The new eye-tracking system makes it possible to perform aphasia tests (auditory comprehension items) comparable to the conventional pointing method.</p>
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Contralaterally controlled functional electrical stimulation immediately improves hand function
Murata Shohei, Koike Yasuharu, Kasukawa Yuji, Saito Kimio, Okada Koki, Kudo Daisuke, Shimada Yoichi, Miyakoshi Naohisa
Japanese Journal of Comprehensive Rehabilitation Science ( 一般社団法人 回復期リハビリテーション病棟協会 ) 13 ( 0 ) 26 - 30 2022年
研究論文（学術雑誌）
<p>Murata S, Koike Y, Kasukawa Y, Saito K, Okada K, Kudo D, Shimada Y, Miyakoshi N. Contralaterally controlled functional electrical stimulation immediately improves hand function. Jpn J Compr Rehabil Sci 2022; 13: 26-30.</p><p><b>Objective</b>: The purpose of this study was to investigate the immediate effects of contralaterally controlled functional electrical stimulation (CCFES) on upper limb function in stroke patients.</p><p><b>Methods</b>: CCFES and mirror therapy (MT) exercises were conducted for 13 stroke patients at least 4 weeks post-onset. A sufficient interval of at least 24 hours was left between the two types of rehabilitation exercises. Before treatment and immediately after each training session, grip strength, Fugl-Meyer Assessment for Upper Extremity (FMA-UE) score and FMA-UE subscores for the shoulder/elbow/forearm, wrist, hand, and coordination were evaluated.</p><p><b>Results</b>: Grip strength, FMA-UE and FMA-UE shoulder/elbow/forearm, wrist, and coordination did not differ significantly after CCFES and MT compared to before therapy. FMA-UE hand did not change significantly after MT compared to before therapy, but it improved significantly after CCFES (<i>p</i> = 0.013).</p><p><b>Conclusion</b>: CCFES for the upper extremities immediately improves hand function and may be effective in maintaining and improving patients' motivation for rehabilitation treatment.</p>
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Tsuchie H.
Journal of Orthopaedic Science ( Journal of Orthopaedic Science ) 2022年
研究論文（学術雑誌）
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Akagawa M.
Acta Medica Okayama ( Acta Medica Okayama ) 76 ( 3 ) 333 - 338 2022年
研究論文（学術雑誌）
We report a case of atypical femoral fracture achieving early fracture union with combination therapy comprising contralateral nail and immediate teriparatide injection. Fracture union of atypical fractures is often delayed due to bowing deformity and bone metabolic disorders. Combination treatment that takes both problems into consideration represents a useful treatment option for atypical femoral fracture.
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大腿四頭筋腱断裂に対する修復術の検討
浅香 康人, 木村 竜太, 小林 孝, 齊藤 英知, 宮腰 尚久
東日本整形災害外科学会雑誌 ( 東日本整形災害外科学会 ) 34 ( 2 ) 116 - 118 2022年
研究論文（学術雑誌）
<p>大腿四頭筋腱断裂に対し，スーチャーアンカー法とpull out法を用いた修復術を直視下・鏡視下に行い，ともに良好な成績を得た．手術時間は鏡視下で長く，手術創は直視下が大きい点が差として挙げられた．患者背景や施設体制に応じて適切な術式を選択するべきである．</p>
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河原木 剛, 木下 隼人, 小林 孝, 石川 慶紀, 菊池 一馬, 宮腰 尚久
東日本整形災害外科学会雑誌 ( 東日本整形災害外科学会 ) 34 ( 2 ) 98 - 102 2022年
研究論文（学術雑誌）
<p>当院で経験した脊髄梗塞10例について検討した．患者背景は，喫煙習慣，心血管因子を数例認め，確定診断までに要した期間は10日だった．薬物治療は，抗血小板薬や抗凝固薬，エダラボン投与などが行われた．リハビリテーションは9例で行われ，5例は独歩まで改善した．脊髄梗塞は患者背景や臨床症状から疑い，繰り返し検査を行うことで確実な診断につながる．確立した薬物療法はないが，ADL改善のためリハビリテーションは積極的に行うべきと考える．</p>
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Association of the bioimpedance phase angle and quality of life in postmenopausal osteoporosis
Ono Y.
Medical Principles and Practice ( Medical Principles and Practice ) 2022年
研究論文（学術雑誌）
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VR・AR技術を用いた上肢リハビリテーションロボットの開発と評価
櫻井 隆弘, 巖見 武裕, 木澤 悟, 斉藤 公男, 島田 洋一, 宮腰 尚久
ロボティクス・メカトロニクス講演会講演概要集 ( 一般社団法人 日本機械学会 ) 2022 ( 0 ) 2A2-E09 2022年
研究論文（学術雑誌）
<p>Upper limbs are often deeply involved in activities of daily living. Therefore, hemiplegic patients need to repeat rehabilitation. We have developed a training robot using Virtual Reality, Augmented Reality, and monitors with the aim of reducing the burden on the therapist and encouraging voluntary rehabilitation. We evaluated the safety and satisfaction of the rehabilitation. From the results, it was found that all training can be safely performed except for some people. We also found that training using Virtual Reality was more satisfying than training using Augmented Reality</p>
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Impact of a specialized outpatient clinic on bone metastasis and its burden on spine surgeons
Tsuchie H.
In Vivo ( In Vivo ) 35 ( 6 ) 3575 - 3579 2021年12月
研究論文（学術雑誌）
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Tsuchie H.
In Vivo ( In Vivo ) 35 ( 6 ) 3467 - 3473 2021年12月
研究論文（学術雑誌）
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Analysis of bone in adenine-induced chronic kidney disease model rats.
Hikaru Saito, Naohisa Miyakoshi, Yuji Kasukawa, Koji Nozaka, Hiroyuki Tsuchie, Chiaki Sato, Kazunobu Abe, Ryo Shoji, Yoichi Shimada
Osteoporosis and sarcopenia 7 ( 4 ) 121 - 126 2021年12月
研究論文（学術雑誌）
OBJECTIVES: The purpose of this study is to investigate the stage of chronic kidney disease (CKD) in adenine-induced CKD model rats by serum analyses, and to examine bone mineral density (BMD), bone strength, and microstructure of trabecular and cortical bone in these rats. METHODS: Eight-week-old, male Wistar rats (n = 42) were divided into 2 groups: those fed a 0.75% adenine diet for 4 weeks until 12 weeks of age to generate CKD model rats (CKD group); and sham rats. The CKD and sham groups were sacrificed at 12, 16, and 20 weeks of age (n = 7 in each group and at 12, 16, and 20 weeks), and various parameters were evaluated, including body weight, renal wet weight, muscle wet weight, renal histology, biochemical tests, BMD, biomechanical testing, and micro-computed tomography (CT). The parameters were compared between the 2 groups at the various time points. RESULTS: In the CKD model rats, at 20 weeks of age, serum creatinine, phosphorus, and intact-PTH levels were elevated, and serum calcium levels were normal, indicating that the CKD was stage IV and associated with secondary hyperparathyroidism. Decreased BMDs of the whole body and the femur were observed as bone changes, and micro-CT analysis showed deterioration of bone microstructure of the cortical bone that resulted in decreased bone strength in the cortical and trabecular bone. CONCLUSIONS: These CKD model rats showed stage IV CKD and appear appropriate for evaluating the effects of several treatments for CKD-related osteoporosis and mineral bone disorder.
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Guideline-based Treatment of Glucocorticoid-induced Osteoporosis in Patients with Rheumatoid Arthritis: A Retrospective Study with the AORA Registry.
Tetsuya Kawano, Naohisa Miyakoshi, Hiroyuki Tsuchie, Takeshi Kashiwagura, Moto Kobayashi, Hiroshi Aonuma, Yusuke Sugimura, Yoichi Shimada
Acta medica Okayama 75 ( 6 ) 699 - 704 2021年12月
研究論文（学術雑誌）
Glucocorticoid-induced osteoporosis (GIOP) is one of the side effects associated with glucocorticoid (GC) therapy. In 2014, the Japanese Society for Bone and Mineral Research (JSBMR) provided new guidelines for the management and treatment of GIOP. The aim of the present study was to clarify the prevalence of patients with rheumatoid arthritis (RA) requiring treatment according to the new guidelines and to identify risk factors associated with lack of treatment in these patients. Patients in the 2018 Akita Orthopedic group on Rheumatoid Arthritis (AORA) database were enrolled. Of 2,234 patients with RA in the database, 683 (30.6%) met the 2014 JSBMR guideline treatment criteria, and 480 (70.3%) had been treated. The untreated group included a larger number of males, younger patients, and patients treated in clinics rather than hospital (p<0.001, p=0.015, and p<0.001, respectively). Multivariate analyses found that male sex, younger age, and clinic-based RA care were significant risk factors associated with lack of treatment (p<0.001, p=0.013, and p<0.001, respectively). Thus, male sex, younger age, and clinic-based care were identified as risk factors.
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手術手技 経皮的椎弓根スクリュー抜釘時の注射シリンジの応用
木村 竜太, 小林 孝, 菊池 一馬, 木下 隼人, 宮腰 尚久, 島田 洋一
臨床整形外科 ( 株式会社医学書院 ) 56 ( 11 ) 1373 - 1375 2021年11月
研究論文（学術雑誌）
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Tomite T.
Knee ( Knee ) 32 121 - 130 2021年10月
研究論文（学術雑誌）
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Miura T.
PLoS ONE ( PLoS ONE ) 16 ( 10 October ) 2021年10月
研究論文（学術雑誌）
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Evaluation of the Nature and Etiologies of Risk Factors for Diaphyseal Atypical Femoral Fractures
Tsuchie H.
Medical Principles and Practice ( Medical Principles and Practice ) 30 ( 5 ) 430 - 436 2021年10月
研究論文（学術雑誌）
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Mita M.
Trauma Case Reports ( Trauma Case Reports ) 34 2021年08月
研究論文（学術雑誌）
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特集 創外固定法Update 下肢の骨折におけるリング型創外固定
野坂 光司, 宮腰 尚久, 河野 哲也, 三田 基樹, 原田 俊太郎, 島田 洋一
関節外科 基礎と臨床 ( メジカルビュー社 ) 40 ( 8 ) 810 - 816 2021年08月
研究論文（学術雑誌）
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症例 薬剤性横紋筋融解症による下肢コンパートメント症候群の1例
太田 真由, 木下 隼人, 阿部 栄二, 小林 孝, 宮腰 尚久, 島田 洋一
整形・災害外科 ( 金原出版 ) 64 ( 9 ) 1155 - 1159 2021年08月
研究論文（学術雑誌）
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特集 骨粗鬆症性椎体骨折-難治例の診断・治療を中心に- 骨粗鬆症性椎体骨折に対する骨切りによる矯正固定術
小林 孝, 阿部 利樹, 菊池 一馬, 木下 隼人, 木村 竜太, 阿部 栄二, 宮腰 尚久, 島田 洋一
関節外科 基礎と臨床 ( メジカルビュー社 ) 40 ( 5 ) 541 - 551 2021年05月
研究論文（学術雑誌）
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Saito H.
Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology ( Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology ) 24 9 - 13 2021年04月
研究論文（学術雑誌）
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Pediatric spinal infection with epidural abscess: A report of two cases
Shoji R.
Surgical Neurology International ( Surgical Neurology International ) 12 2021年04月
研究論文（学術雑誌）
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特集 疾患別 臨床・上肢機能アプローチ-機能・活動・生活へ 頸髄損傷四肢麻痺の上肢機能アプローチ
千田 聡明, 加賀美 開, 松永 俊樹, 宮腰 尚久, 島田 洋一
作業療法ジャーナル ( 三輪書店 ) 55 ( 4 ) 342 - 347 2021年04月
研究論文（学術雑誌）
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特集 運動器のバイオメカニクス-Cutting Edge 2021:新しい解析手法と知見 Ⅰ.脊椎のバイオメカニクスと下肢アライメント 三次元筋骨格モデルを用いた脊柱変形解析
本郷 道生, 宮腰 尚久, 島田 洋一
整形・災害外科 ( 金原出版 ) 64 ( 5 ) 507 - 514 2021年04月
研究論文（学術雑誌）
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Tsuchie H.
Bone ( Bone ) 143 2021年02月
研究論文（学術雑誌）
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Miura T.
Journal of Orthopaedics ( Journal of Orthopaedics ) 23 78 - 82 2021年01月
研究論文（学術雑誌）
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Ishikawa Y.
World Neurosurgery ( World Neurosurgery ) 145 83 - 88 2021年01月
研究論文（学術雑誌）
-
Sato C.
Journal of Bone and Mineral Metabolism ( Journal of Bone and Mineral Metabolism ) 2021年
研究論文（学術雑誌）
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Tsukamoto Hiroaki, Shimada Yoichi, Saito Kimio, Matsunaga Toshiki, Iwami Takehiro, Saito Hidetomo, Kijima Hiroaki, Akagawa Manabu, Komatsu Akira, Miyakoshi Naohisa
Progress in Rehabilitation Medicine ( 公益社団法人 日本リハビリテーション医学会 ) 6 ( 0 ) 2021年
研究論文（学術雑誌）
<p><b>Objectives: </b>The purpose of this study was to clarify the diagnostic accuracy of the mobile assessment of varus thrust using inertial measurement units (IMUs).</p><p><b>Methods: </b>A total of 80 knees in 49 patients were enrolled in this study. On visual analysis of gait to determine the presence or absence of varus thrust, 23 knees were assigned to the Present group, 17 to the Ambiguous group, and 40 to the Absent group. The peak knee varus angular velocities (PVVs), measured by quantitative gait analysis using nine-axis IMUs, were compared between these three groups. A receiver operating characteristic curve for the relationship between the visual assessment of varus thrust (Present and Ambiguous) and the measured PVV was created, and the cut-off PVV for visualized varus thrust was determined as the highest point for both sensitivity and specificity.</p><p><b>Results: </b>The mean PVVs were significantly different between the three groups (Present, 47.7 ± 8.2 degree/s, Ambiguous, 34.1 ± 10.5 degree/s, and Absent, 28.1 ± 8.3 degree/s, respectively, ANOVA P=0.000). The PVV cut-off value for visualized varus thrust was 28.1 degree/s, yielding a sensitivity of 0.957 and a specificity of 0.579.</p><p><b>Conclusions: </b>A PVV <28.1 degree/s is useful for ruling out varus thrust during gait. This quantitative varus thrust assessment method using IMUs has clinical utility as a screening test.</p>
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Iida J.
Surgical Neurology International ( Surgical Neurology International ) 12 2021年
研究論文（学術雑誌）
-
Tomioka T.
Advances in Orthopedics ( Advances in Orthopedics ) 2021 2021年
研究論文（学術雑誌）
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Kijima H.
Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders ( Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders ) 14 2021年
研究論文（学術雑誌）
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The Effects of Trends in Osteoporosis Treatment on the Incidence of Fractures
Horikawa A.
Journal of Osteoporosis ( Journal of Osteoporosis ) 2021 2021年
研究論文（学術雑誌）
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斉藤 公男, 工藤 大輔, 千田 聡明, 畠山 和利, 渡邉 基起, 松永 俊樹, 宮腰 尚久, 島田 洋一
The Japanese journal of rehabilitation medicine = リハビリテーション医学 ( 公益社団法人 日本リハビリテーション医学会 ) 58 ( 3 ) 314 - 316 2021年
研究論文（学術雑誌）
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Inoue G.
Spine Surgery and Related Research ( Spine Surgery and Related Research ) 5 ( 4 ) 252 - 263 2021年
研究論文（学術雑誌）
<p>Introduction: Chronic low back pain (CLBP) is a leading cause of disability, yet there is limited high-quality evidence to identify the most suitable pharmacological therapy. The purpose of this Japanese nationwide, multicenter, prospective study was to compare the effectiveness of four representative drug therapies-acetaminophen, celecoxib, loxoprofen, and a tramadol and acetaminophen (T+A) combination drug-to establish evidence for a drug of choice for CLBP.</p><p>Methods: Patients with CLBP (N=471) received one of the four treatments and were evaluated, prospectively and comprehensively, once every month for six months using a visual analog scale (VAS) for LBP, the Japanese Orthopedic Association (JOA) score, the JOA Back Pain Evaluation Questionnaire (JOABPEQ), the Roland-Morris Disability Questionnaire (RDQ), the EuroQol five-dimensions three-levels (EQ-5D-3L), and the Short Form-8 item health survey (SF-8). We conducted multivariable linear regression analyses of the four drugs at 1 and 6 months after drug allocation. Differences with <i>P</i><0.05 were considered statistically significant.</p><p>Results: Patients who received acetaminophen showed a significant improvement from baseline in the mental health subscale of the JOABPEQ at one month (<i>P</i>=0.02) and the JOA score at six months (<i>P</i><0.01). None of the other outcome measures among the four drugs differed significantly. Across groups, all outcome measures, except the mental component summary (MCS) score of the SF-8, improved equivalently, although most measurements showed no obvious cumulative effect over six months. The MCS score of the SF-8 decreased gradually over six months in all groups.</p><p>Conclusions: Most of the outcome measures among the treated groups were not significantly different, indicating similar treatment effects of the four drugs for CLBP. Our study indicated the limit of each outcome measure for evaluating the patient status, suggesting that a single outcome measure is insufficient to reflect treatment effectiveness.</p>
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Tsuchie H.
Acta Medica Okayama ( Acta Medica Okayama ) 75 ( 4 ) 533 - 538 2021年
研究論文（学術雑誌）
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Deep Angiomyxoma of the Thigh That Is Difficult to Diagnose: A Case Report and Literature Review
Tsuchie H.
Acta Medica Okayama ( Acta Medica Okayama ) 75 ( 5 ) 653 - 657 2021年
研究論文（学術雑誌）
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Kawano T.
Acta Medica Okayama ( Acta Medica Okayama ) 75 ( 6 ) 699 - 704 2021年
研究論文（学術雑誌）
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Ishikawa Y.
Surgical Neurology International ( Surgical Neurology International ) 12 2021年
研究論文（学術雑誌）
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Deep Angiomyxoma of the Thigh That Is Difficult to Diagnose: A Case Report and Literature Review.
Hiroyuki Tsuchie, Naohisa Miyakoshi, Hiroyuki Nagasawa, Hiroshi Nanjo, Yoichi Shimada
Acta medica Okayama 75 ( 5 ) 653 - 657 2021年
研究論文（学術雑誌）
We present an extremely rare case of deep angiomyxoma (DAM) in the thigh that was misdiagnosed as desmoid-type fibromatosis. A 40-year-old Japanese woman presented with a mass on the left thigh. The histological diagnosis by needle biopsy was desmoid-type fibromatosis; the tumor grew slowly and was resected 4 years later. The histological diagnosis from the resected tumor was DAM. As of 16 months post-surgery, the patient has not noticed any local recurrence. Although DAM in a lower extremity is extremely rare, clinicians must be aware of its possible occurrence in areas relatively close to the pelvis.
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Impact of a Specialized Outpatient Clinic on Bone Metastasis and Its Burden on Spine Surgeons
HIROYUKI TSUCHIE, NAOHISA MIYAKOSHI, MICHIO HONGO, HIROYUKI NAGASAWA, YUJI KASUKAWA, DAISUKE KUDO, RYOTA KIMURA
In Vivo ( Anticancer Research USA Inc. ) 35 ( 6 ) 3575 - 3579 2021年
研究論文（学術雑誌）
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Kimura R.
Spinal Cord Series and Cases ( Spinal Cord Series and Cases ) 6 ( 1 ) 2020年12月
研究論文（学術雑誌）
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Growing Rod Surgery for Early-Onset Scoliosis in an Osteogenesis Imperfecta Patient
Ono Y.
World Neurosurgery ( World Neurosurgery ) 144 178 - 183 2020年12月
研究論文（学術雑誌）
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Ishikawa Y.
World Neurosurgery ( World Neurosurgery ) 144 82 - 87 2020年12月
研究論文（学術雑誌）
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Saito H.
Journal of Experimental Orthopaedics ( Journal of Experimental Orthopaedics ) 7 ( 1 ) 2020年12月
研究論文（学術雑誌）
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Abe K.
Surgical Neurology International ( Surgical Neurology International ) 11 2020年12月
研究論文（学術雑誌）
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Ultrasound-guided total dorsal ramus block for the treatment of chronic low back pain
Kimura R.
Journal of Orthopaedics, Trauma and Rehabilitation ( Journal of Orthopaedics, Trauma and Rehabilitation ) 27 ( 2 ) 128 - 132 2020年12月
研究論文（学術雑誌）
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特集 脊椎骨粗鬆症性椎体骨折に対する治療戦略-薬物療法を中心にUP TO DATE 椎体骨折予防と治療における至適な薬物療法について-デノスマブ,テリパラチド,ロモソズマブの使い分け
宮腰 尚久
脊椎脊髄ジャーナル ( 三輪書店 ) 33 ( 12 ) 1097 - 1103 2020年12月
研究論文（学術雑誌）
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Yamada K.
Journal of Orthopaedic Science ( Journal of Orthopaedic Science ) 25 ( 6 ) 1084 - 1092 2020年11月
研究論文（学術雑誌）
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Okudera Y.
Journal of Orthopaedics ( Journal of Orthopaedics ) 22 220 - 224 2020年11月
研究論文（学術雑誌）
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Miyakoshi N.
World Neurosurgery ( World Neurosurgery ) 142 239 - 245 2020年10月
研究論文（学術雑誌）
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Murahashi Y.
European Radiology ( European Radiology ) 30 ( 10 ) 5768 - 5776 2020年10月
研究論文（学術雑誌）
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骨粗鬆症と骨粗鬆症関連骨折に対する診断と治療 Ⅵ.下肢骨折の病態と治療 秋田県の100歳以上超高齢者大腿骨近位部骨折に対する手術および骨粗鬆症治療介入の現状
三田 基樹, 野坂 光司, 宮腰 尚久, 島田 洋一
別冊整形外科 ( 南江堂 ) 1 ( 78 ) 200 - 203 2020年10月
研究論文（学術雑誌）
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Nozaka K.
BMC Musculoskeletal Disorders ( BMC Musculoskeletal Disorders ) 21 ( 1 ) 2020年09月
研究論文（学術雑誌）
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Impact of acridine orange in patients with local recurrent soft tissue sarcoma
Tsuchie H.
In Vivo ( In Vivo ) 34 ( 5 ) 2745 - 2750 2020年09月
研究論文（学術雑誌）
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特集 病態に応じた腰痛のリハビリテーション診療 高齢者の脊柱変形に伴う腰痛
島田 洋一, 本郷 道生, 宮腰 尚久
総合リハビリテーション ( 株式会社医学書院 ) 48 ( 9 ) 827 - 834 2020年09月
研究論文（学術雑誌）
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Prognostic significance of histological subtype in soft tissue sarcoma with distant metastasis
Tsuchie H.
In Vivo ( In Vivo ) 34 ( 4 ) 1975 - 1980 2020年08月
研究論文（学術雑誌）
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Osteochondritis dissecans of the glenoid in a 13-year-old baseball player: A case report
Seki N.
Sports Orthopaedics and Traumatology ( Sports Orthopaedics and Traumatology ) 36 ( 2 ) 155 - 162 2020年06月
研究論文（学術雑誌）
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Tsukamoto H.
Knee ( Knee ) 27 ( 3 ) 838 - 845 2020年06月
研究論文（学術雑誌）
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Effectiveness of circular external fixator in periprosthetic fractures around the knee
Nozaka K.
BMC Musculoskeletal Disorders ( BMC Musculoskeletal Disorders ) 21 ( 1 ) 2020年05月
研究論文（学術雑誌）
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Hatakeyama Y.
Journal of Orthopaedic Science ( Journal of Orthopaedic Science ) 25 ( 3 ) 503 - 506 2020年05月
研究論文（学術雑誌）
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Recurrent dysphagia after lower posterior cervical fusion
Ishikawa Y.
Surgical Neurology International ( Surgical Neurology International ) 11 ( 114 ) 2020年05月
研究論文（学術雑誌）
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特集 脊椎脊髄疾患に対する分類・評価法 第9章 骨粗鬆症 骨粗鬆症の診断基準
宮腰 尚久
脊椎脊髄ジャーナル ( 三輪書店 ) 33 ( 4 ) 494 - 496 2020年04月
研究論文（学術雑誌）
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鏡視下手術の進歩--小関節から脊椎まで Ⅴ.股関節 股関節関節外病変に対する鏡視下手術
藤井 昌, 加谷 光規, 木島 泰明, 河野 哲也, 宮腰 尚久, 島田 洋一
別冊整形外科 ( 南江堂 ) 1 ( 77 ) 172 - 176 2020年04月
研究論文（学術雑誌）
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Yuasa Y.
Journal of Bone and Mineral Metabolism ( Journal of Bone and Mineral Metabolism ) 38 ( 2 ) 179 - 187 2020年03月
研究論文（学術雑誌）
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Factors affecting continuation of weekly teriparatide administration in rural areas
Tsuchie H.
Journal of Bone and Mineral Metabolism ( Journal of Bone and Mineral Metabolism ) 38 ( 2 ) 248 - 253 2020年03月
研究論文（学術雑誌）
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Nozaka K.
BMC Musculoskeletal Disorders ( BMC Musculoskeletal Disorders ) 21 ( 1 ) 2020年03月
研究論文（学術雑誌）
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特集 骨粗鬆症性椎体骨折治療の最新知見 骨粗鬆症・椎体骨折治療体系における運動療法の役割
本郷 道生, 宮腰 尚久, 島田 洋一
整形・災害外科 ( 金原出版 ) 63 ( 2 ) 157 - 163 2020年02月
研究論文（学術雑誌）
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Effectiveness of distal tibial osteotomy with distraction arthroplasty in varus ankle osteoarthritis
Nozaka K.
BMC Musculoskeletal Disorders ( BMC Musculoskeletal Disorders ) 21 ( 1 ) 2020年01月
研究論文（学術雑誌）
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Miyakoshi N.
Spine Surgery and Related Research ( Spine Surgery and Related Research ) 4 ( 3 ) 208 - 215 2020年01月
研究論文（学術雑誌）
<p>Introduction: Chronic low back pain (CLBP) is a major health burden worldwide and requires patient satisfaction with treatment. Consultation length can be an important factor in patient satisfaction, but few studies have investigated the impact of consultation length on satisfaction in patients with CLBP. This study tried to elucidate the impact of consultation length on clinical outcomes in patients with CLBP.</p><p>Methods: This study is part of an analysis using the database of the nationwide, multicenter cohort for CLBP performed by the Project Committee of the Japanese Society for Spine Surgery and Related Research. A total of 427 patients aged 20-85 years (median age, 73.0 years; female, 58.6%) with CLBP were prospectively followed-up monthly for 6 months. Multivariable nonlinear regression analyses were performed to assess the effect of consultation length on outcome measures including subjective satisfaction score, EuroQol 5-dimension, Japanese Orthopaedic Association (JOA) score, Roland-Morris Disability Questionnaire, JOA Back Pain Evaluation Questionnaire, visual analog scale (VAS) and Medical Outcome Survey short-form 8-item health survey that evaluated at the next phase. Furthermore, we assessed whether the effect of consultation length on patient satisfaction was modified by the baseline Brief Scale for Psychiatric Problems in Orthopaedic Patients (BS-POP) score for patient and physician versions.</p><p>Results: VAS for CLBP was the only score that correlated significantly with consultation length (P = 0.018). Satisfaction score showed a significant positive correlation with consultation length in patients with the highest baseline BS-POP scores (P < 0.2). Moreover, consultation lengths more than 7.6 min and 15.1 min offered increase of satisfaction if patients show the highest BS-POP scores on patient and physician versions, respectively.</p><p>Conclusions: These findings suggest that a sufficiently long consultation is an important factor for subjective satisfaction in the patients with CLBP, particularly in patients with psychological problems.</p>
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Murata S.
International Journal of Surgery Case Reports ( International Journal of Surgery Case Reports ) 77 510 - 514 2020年01月
研究論文（学術雑誌）
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Treatment of spontaneous osteonecrosis of the knee by daily teriparatide: A report of 3 cases
Horikawa A.
Medicine ( Medicine ) 99 ( 5 ) 2020年01月
研究論文（学術雑誌）
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Kawano T.
Advances in Orthopedics ( Advances in Orthopedics ) 2020 2020年
研究論文（学術雑誌）
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Miyakoshi N.
Spinal Cord ( Spinal Cord ) 2020年
研究論文（学術雑誌）
-
Miyakoshi N.
Surgical Neurology International ( Surgical Neurology International ) 11 2020年
研究論文（学術雑誌）
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Fujii M.
Journal of Orthopaedic Science ( Journal of Orthopaedic Science ) 2020年
研究論文（学術雑誌）
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Inoue Gen, Taguchi Toshihiko, Haro Hirotaka, Taneichi Hiroshi, Yamazaki Masashi, Nishida Kotaro, Yamada Hiroshi, Kabata Daijiro, Shintani Ayumi, Iwasaki Motoki, Ito Manabu, Kaito Takashi, Miyakoshi Naohisa, Murakami Hideki, Yonenobu Kazuo, Takura Tomoyuki, Mochida Joji, Matsuyama Yukihiro, Yamashita Toshihiko, Kawakami Mamoru, Takahashi Kazuhisa, Yoshida Munehito, Imagama Shiro, Ohtori Seiji
Spine Surgery and Related Research ( 一般社団法人 日本脊椎脊髄病学会 ) 2020年
研究論文（学術雑誌）
<p><b>Introduction: </b>Chronic low back pain (CLBP) is a leading cause of disability, yet there is limited high-quality evidence to identify the most suitable pharmacological therapy. The purpose of this Japanese nationwide, multicenter, prospective study was to compare the effectiveness of four representative drug therapies—acetaminophen, celecoxib, loxoprofen, and a tramadol and acetaminophen (T+A) combination drug—to establish evidence for a drug of choice for CLBP.</p><p><b>Methods: </b>Patients with CLBP (N = 471) received one of the four treatments and were evaluated, prospectively and comprehensively, once every month for six months using a visual analog scale (VAS) for LBP, the Japanese Orthopedic Association (JOA) score, the JOA Back Pain Evaluation Questionnaire (JOABPEQ), the Roland–Morris Disability Questionnaire (RDQ), the EuroQol five-dimensions three-levels (EQ-5D-3L), and the Short Form-8 item health survey (SF-8). We conducted multivariable linear regression analyses of the four drugs at 1 and 6 months after drug allocation. Differences with P < 0.05 were considered statistically significant.</p><p><b>Results: </b>Patients who received acetaminophen showed a significant improvement from baseline in the mental health subscale of the JOABPEQ at one month (<i>P</i> = 0.02) and the JOA score at six months (<i>P</i> < 0.01). None of the other outcome measures among the four drugs differed significantly. Across groups, all outcome measures, except the mental component summary (MCS) score of the SF-8, improved equivalently, although most measurements showed no obvious cumulative effect over six months. The MCS score of the SF-8 decreased gradually over six months in all groups.</p><p><b>Conclusions: </b>Most of the outcome measures among the treated groups were not significantly different, indicating similar treatment effects of the four drugs for CLBP. Our study indicated the limit of each outcome measure for evaluating the patient status, suggesting that a single outcome measure is insufficient to reflect treatment effectiveness.</p>
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Miyakoshi Naohisa, Masutani Norimitsu, Kasukawa Yuji, Kudo Daisuke, Saito Kimio, Matsunaga Toshiki, Shimada Yoichi
Progress in Rehabilitation Medicine ( 公益社団法人 日本リハビリテーション医学会 ) 5 ( 0 ) 2020年
研究論文（学術雑誌）
<p><b>Objectives: </b>Previous studies have suggested that the effects of vitamin D in preventing osteoporotic fractures result in part from its influence on fall prevention. However, the effects of vitamin D on dynamic balance as a contributor to fall prevention have not been fully evaluated. Moreover, few studies have compared the effects of native and active forms of vitamin D. The objective of this preliminary randomized prospective study was to compare the effects of native vitamin D and eldecalcitol on muscular strength and dynamic balance in postmenopausal patients undergoing denosumab treatment for osteoporosis.</p><p><b>Methods: </b>A total of 30 women with postmenopausal osteoporosis were randomly assigned to a native D group (administered denosumab and native vitamin D with calcium) or an ELD group (administered denosumab and eldecalcitol) and were followed up for 6 months. The following parameters were compared: the strengths of the back extensor and lower extremity muscles; static balance evaluated using the one-leg standing test; and dynamic balance evaluated using the 10-m walk test, the functional reach test, the timed up and go test, and the total length of the trajectory of the center of gravity (LNG) measured using a dynamic sitting balance measurement device.</p><p><b>Results: </b>Compared to baseline measurements, back extensor and knee extensor strengths had significantly increased after 6 months of treatment in the native D group (P<0.05) but not in the ELD group. In contrast, LNG significantly improved in both groups after 6 months (P<0.05). No significant differences between the two groups were seen in any of these measured parameters after treatment.</p><p><b>Conclusions: </b>Both native vitamin D + denosumab and eldecalcitol + denosumab were effective for improving dynamic sitting balance in postmenopausal women with osteoporosis.</p>
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Diagnosis of presarcopenia using body height and arm span for postmenopausal osteoporosis
Ono Y.
Clinical Interventions in Aging ( Clinical Interventions in Aging ) 15 357 - 361 2020年
研究論文（学術雑誌）
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Effectiveness of Ilizarov external fixation in elderly patients with pilon fractures
Nozaka K.
Journal of Orthopaedic Science ( Journal of Orthopaedic Science ) 2020年
研究論文（学術雑誌）
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Okuyama K.
Acta Orthopaedica et Traumatologica Turcica ( Acta Orthopaedica et Traumatologica Turcica ) 54 ( 6 ) 647 - 650 2020年
研究論文（学術雑誌）
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Imagama S.
Journal of Orthopaedic Science ( Journal of Orthopaedic Science ) 2020年
研究論文（学術雑誌）
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Kudo D.
Journal of Back and Musculoskeletal Rehabilitation ( Journal of Back and Musculoskeletal Rehabilitation ) 33 ( 2 ) 263 - 268 2020年
研究論文（学術雑誌）
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Initial Rotational Instability of the Tapered Wedge-Shaped Type Cementless Stem
Iwamoto Y.
Advances in Orthopedics ( Advances in Orthopedics ) 2020 2020年
研究論文（学術雑誌）
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Kasukawa Yuji, Miyakoshi Naohisa, Hongo Michio, Ishikawa Yoshinori, Kudo Daisuke, Kimura Ryota, Ono Yuichi, Shimada Yoichi
Progress in Rehabilitation Medicine ( 公益社団法人 日本リハビリテーション医学会 ) 5 ( 0 ) 2020年
研究論文（学術雑誌）
<p><b>Objectives: </b>The extent to which locomotive syndrome is associated with low back pain (LBP), health-related quality of life (HRQOL), and impairment of activities of daily living among elderly men and women remains poorly documented. This study evaluated associations between locomotive syndrome and both HRQOL and LBP as assessed using a questionnaire completed by elderly individuals, including some >80 years old.</p><p><b>Methods: </b>We conducted a survey assessing locomotive syndrome using the loco-check, HRQOL using the Short-Form 36 questionnaire (SF-36), and LBP using the Roland-Morris Disability Questionnaire (RDQ) among individuals >60 years old. SF-36 and RDQ scores were compared between 253 subjects with and without locomotive syndrome.</p><p><b>Results: </b>Fifty-seven men (48%) and 71 women (53%) were diagnosed with locomotive syndrome. Subjects of both sexes with locomotive syndrome scored significantly lower for eight items from SF-36. Physical and mental component summary scores were significantly worse in women with locomotive syndrome in their 60s and 70s. RDQ scores were significantly higher in participants with locomotive syndrome for men in their 60s and for both men and women in their 70s.</p><p><b>Conclusions: </b>Locomotive syndrome was associated with impaired HRQOL and worse LBP among men and women >60 years old. Differences in HRQOL and LBP between subjects with and without locomotive syndrome were significant for both men and women in their 60s and 70s, but not in their 80s. Locomotive syndrome should be prevented to maintain HRQOL, particularly for men and women in their 60s and 70s.</p>
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Tsuchie H.
Medical principles and practice : international journal of the Kuwait University, Health Science Centre ( Medical principles and practice : international journal of the Kuwait University, Health Science Centre ) 29 ( 6 ) 538 - 543 2020年
研究論文（学術雑誌）
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Kikuchi K.
Journal of Orthopaedic Science ( Journal of Orthopaedic Science ) 2020年
研究論文（学術雑誌）
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Relationship between Dynamic Trunk Balance and the Balance Evaluation Systems Test in Elderly Women
Takahashi Yasuhiro, Saito Kimio, Matsunaga Toshiki, Iwami Takehiro, Kudo Daisuke, Tate Kengo, Miyakoshi Naohisa, Shimada Yoichi
Progress in Rehabilitation Medicine ( 公益社団法人 日本リハビリテーション医学会 ) 5 ( 0 ) 2020年
研究論文（学術雑誌）
<p><b>Objective</b>: Falls are major contributors to elderly subjects becoming bedridden. Consequently, it is important to evaluate and minimize the risk of falls in the elderly. Trunk stability is important for balance function and is related to fall prevention in elderly women. We developed a balance-measuring device that uses a dynamic sitting position to safely measure balance function. The Balance Evaluation Systems Test (BESTest) is useful method to assess balance function, a recently developed balance evaluation test that can detect minor balance problems not captured by previous tests. The purpose of the present study was to examine the relationship between dynamic trunk balance and findings of the BESTest in elderly women. <b>Methods</b>: Thirty-one healthy women aged 60 years or more participated in this study. The evaluation items were the BESTest total score, scores for each of the six elements of the BESTest, dynamic sitting balance, static postural balance, and muscle strength. <b>Results</b>: The mean total BESTest score was 85.4 points. The mean total trajectory length of the center of gravity (COG) during the dynamic sitting balance test was 1447.5 mm. A negative correlation (r=–0.481, P= 0.006) was observed between the total COG trajectory length and the BESTest score. A negative correlation was also found between the total COG trajectory length and biomechanical constraints (r=–0.492, P=0.005) and anticipatory postural adjustments (r=–0.532, P=0.002). There were no correlations between the dynamic sitting balance total COG trajectory length and the stationary standing COG trajectory length or muscle strength. <b>Conclusions</b>: In elderly women, the total COG trajectory length during dynamic sitting was negatively correlated with the BESTest total score.</p>
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Spinal Cord Compression with Occult Bony Fragment in Osteoporotic Vertebral Fracture: A Case Report
Ishikawa Yoshinori, Miyakoshi Naohisa, Hongo Michio, Kasukawa Yuji, Kudo Daisuke, Shimada Yoichi
Spine Surgery and Related Research ( 一般社団法人 日本脊椎脊髄病学会 ) 2020年
研究論文（学術雑誌）
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The Differences in Imaging Findings Between Painless and Painful Osteoarthritis of the Hip
Kijima H.
Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders ( Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders ) 13 2020年
研究論文（学術雑誌）
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柏倉 剛, 青沼 宏, 河野 哲也, 宮腰 尚久, 島田 洋一
The Japanese journal of rehabilitation medicine = リハビリテーション医学 ( 公益社団法人 日本リハビリテーション医学会 ) 57 ( 11 ) 1054 - 1061 2020年
研究論文（学術雑誌）
<p>RA治療は新規薬剤の登場により向上した．RCTでは複雑化した実臨床を表すことが困難であり，観察研究としてのコホート研究が重要である．国内には数多くの優れたRAコホート研究があり，数多くの臨床的知見を出している．秋田県は，長期間全国一の高齢化率を継続しており，高齢RA患者が多い．また，高齢者は遠方への通院が困難なため，RA治療の標準化と地域格差解消をめざし，秋田大学整形外科は2010年に秋田整形外科リウマチグループ（AORA）を立ち上げ，実態調査のためAORAレジストリーを構築した．今回，AORAを含め国内のRAコホートについて概説した．</p>
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外側型膝OAを伴った成人の下腿外捻変形に対してDouble Level Osteotomyを行った１例
村田 昇平, 佐々木 香奈, 赤川 学, 塚本 泰郎, 宮腰 尚久, 齊藤 英知, 斉藤 公男, 千田 秀一, 山村 俊昭, 佐藤 貴博, 島田 洋一, 木島 泰明, 藤井 昌
東北膝関節研究会会誌 ( 東北膝関節研究会 ) 29 ( 0 ) 13 - 17 2020年
研究論文（学術雑誌）
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大腿骨ステム周囲骨折のタイプ分類と治療法の選択:—骨折線が存在するエリアに基づく分類—
木島 泰明, 田澤 浩, 谷 貴行, 鈴木 紀夫, 加茂 啓志, 佐々木 研, 岩本 陽輔, 長幡 樹, 三浦 隆徳, 藤井 昌, 河野 哲也, 島田 洋一, 宮腰 尚久, 奥寺 良弥, 小西 奈津雄, 久保田 均, 山田 晋
日本関節病学会誌 ( 日本関節病学会 ) 39 ( 4 ) 362 - 366 2020年
研究論文（学術雑誌）
<p><b>目的 : </b>ステム周囲骨折は治療に難渋することが多いが, まとまった報告が少ない。今回我々は可及的に多くの症例の傾向と特徴を調査した。</p><p><b>方法 : </b>対象は2006年3月から2018年3月までに受診した大腿骨ステム周囲骨折患者51名とし, バンクーバー分類での骨折タイプ, 先行手術の種類, 先行手術のステム固定様式, 先行手術からの経過時間, ステム周囲骨折への治療方法を調査した。</p><p><b>結果 : </b>バンクーバー分類Type Aが5.9%, Type B1が47%, Type B2が20%, Type B3が2.0%, Type Cが25%だった。先行手術のステム固定様式はセメントレスが76%, セメントが24%だった。先行手術からステム周囲骨折までの期間は平均8年7か月だったが, 1年以内の症例が24%と最も多かった。治療方法は骨接合術が53%に, 再置換術が39%に行われていた。ステムのゆるみがないと判断されたType B1に対しても33%で再置換術が施行されていた。ステムのゆるみがあると判断されたType B2およびB3はすべて再置換術が行われていた。</p><p><b>考察 : </b>先行手術から1年以内にステム周囲骨折が多いことから人工股関節置換術後または人工骨頭置換術後すぐに骨粗鬆症治療や転倒予防措置などのステム周囲骨折の予防を行うべきである。また, ステム周囲骨折の治療方針について調査した結果, ステムの固定様式と骨折線の位置によって手術様式を決定できる可能性が示唆された。</p>
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高橋 靖博, 斉藤 公男, 木島 泰明, 齊藤 英知, 宮腰 尚久, 島田 洋一, 関 展寿, 岡本 憲人, 佐藤 千恵, 加茂 啓志, 木戸 忠人, 奥山 幸一郎, 千葉 光穂, 藤井 昌
東北膝関節研究会会誌 ( 東北膝関節研究会 ) 29 ( 0 ) 35 - 39 2020年
研究論文（学術雑誌）
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後期高齢者橈骨遠位端骨折に対するStellar 2 plate<sup>®</sup>の治療成績
湯浅 悠介, 千馬 誠悦, 成田 裕一郎, 伊藤 博紀, 宮腰 尚久, 島田 洋一
東日本整形災害外科学会雑誌 ( 東日本整形災害外科学会 ) 32 ( 4 ) 570 - 573 2020年
研究論文（学術雑誌）
<p>後期高齢者橈骨遠位端骨折に対するStellar 2 plate<sup>®</sup>の治療成績を検討した．全症例における各X線パラメーターの推移は，ulnar varianceで有意に矯正損失が生じていたが，臨床成績は良好で合併症は認めなかった．骨折型別ではtype Aに比べtype Cで有意にulnar varianceの矯正損失が生じていたが，臨床成績は骨折型による差を認めず，おおむね良好であった．</p>
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高橋 靖博, 佐々木 香奈, 齊藤 英知, 藤井 昌, 木島 泰明, 宮腰 尚久, 島田 洋一, 斉藤 公男, 関 展寿, 佐藤 千恵
東北膝関節研究会会誌 ( 東北膝関節研究会 ) 29 ( 0 ) 41 - 46 2020年
研究論文（学術雑誌）
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脆弱性骨盤骨折におけるMRIを使用したRommens分類での診断一致率・検者間一致率の検討
三浦 隆徳, 蝦名 寿仁, 谷 貴行, 千田 秀一, 宮腰 尚久, 島田 洋一
東日本整形災害外科学会雑誌 ( 東日本整形災害外科学会 ) 32 ( 1 ) 112 - 116 2020年
研究論文（学術雑誌）
<p>脆弱性骨盤骨折（FFP）に対するRommens分類の診断一致率の報告でMRIを併用したものはない．FFP32例（男5例，女27例，平均年齢85.7歳）をRommens分類で分類し診断一致率を検討した．MRIは17例で行われ診断一致率は81.2％，Kappa係数は0.72だった．仙骨骨折の同定が要因でtype IIの診断一致率が58.3％と低く，正確な分類には仙骨全体を含めたMRIが有効である．</p>
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本郷 道生, 宮腰 尚久, 島田 洋一
日本整形外科スポーツ医学会雑誌 ( 一般社団法人 日本整形外科スポーツ医学会 ) 40 ( 2 ) 135 - 140 2020年
研究論文（学術雑誌）
<p>高齢者において，骨粗鬆症性椎体骨折後の変形や，椎間板，靱帯の変性，筋力低下による脊柱変形や，腰部脊柱管狭窄症が生じ，慢性の腰背部痛，下肢痛，身体機能低下を生じて，生活の質（QOL）は低下する．これらの脊椎変性疾患に対してさまざまな保存療法が行なわれるが，運動療法も有効とされる．運動療法やスポーツ活動を行なって，体幹の筋力や可動性，体力を改善させることにより，低下した身体機能や，QOL，姿勢そして腰背部痛の改善に有効であることが示されている．</p>
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Miyakoshi N.
World Neurosurgery ( World Neurosurgery ) 132 63 - 66 2019年12月
研究論文（学術雑誌）
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Hagino H.
Journal of Bone and Mineral Metabolism ( Journal of Bone and Mineral Metabolism ) 37 ( 6 ) 1013 - 1023 2019年11月
研究論文（学術雑誌）
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Miyakoshi N.
World Neurosurgery ( World Neurosurgery ) 131 38 - 42 2019年11月
研究論文（学術雑誌）
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Kimura R.
Clinical Spine Surgery ( Clinical Spine Surgery ) 32 ( 8 ) E380 - E385 2019年10月
研究論文（学術雑誌）
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Kaito T.
Journal of Orthopaedic Science ( Journal of Orthopaedic Science ) 24 ( 5 ) 805 - 811 2019年09月
研究論文（学術雑誌）
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Tsuchie H.
Medical Principles and Practice ( Medical Principles and Practice ) 28 ( 5 ) 425 - 431 2019年09月
研究論文（学術雑誌）
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Unoki E.
Spine ( Spine ) 44 ( 17 ) E1024 - E1030 2019年09月
研究論文（学術雑誌）
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Kobayashi T.
Journal of Medical Case Reports ( Journal of Medical Case Reports ) 13 ( 1 ) 2019年08月
研究論文（学術雑誌）
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特集 リハビリテーション医学・医療の最前線 FESを用いた運動機能再建とリハビリテーション医療
松永 俊樹, 島田 洋一, 宮腰 尚久, 工藤 大輔, 斉藤 公男, 木村 竜太
整形・災害外科 ( 金原出版 ) 62 ( 9 ) 1075 - 1082 2019年08月
研究論文（学術雑誌）
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Ishikawa Y.
European Spine Journal ( European Spine Journal ) 28 ( 7 ) 1670 - 1677 2019年07月
研究論文（学術雑誌）
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特集 骨脆弱を伴う骨折の治療 非定型大腿骨骨折治療のピットフォール
土江 博幸, 宮腰 尚久, 島田 洋一
関節外科 ( (株)メジカルビュー社 ) 38 ( 7 ) 728 - 735 2019年07月
研究論文（学術雑誌）
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An epidemiological study of traumatic spinal cord injuries in the fastest aging area in Japan
Kudo D.
Spinal Cord ( Spinal Cord ) 57 ( 6 ) 509 - 515 2019年06月
研究論文（学術雑誌）
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誌上シンポジウム 変形性膝関節症における関節温存手術 変形性膝関節症に対するClosed Wedge High Tibial Osteotomy-われわれの考えるHybrid Closed Wedge High Tibial Osteotomyの適応
齊藤 英知, 島田 洋一, 斉藤 公男, 山村 俊昭, 佐藤 貴博, 髙橋 靖博, 村田 昇平, 野坂 光司, 木島 泰明, 藤井 昌, 宮腰 尚久
臨床整形外科 ( 株式会社医学書院 ) 54 ( 6 ) 561 - 568 2019年06月
研究論文（学術雑誌）
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腰部多裂筋の姿勢変化に伴う超音波せん断波エラストグラフィを用いた弾性度変化
木村 竜太, 宮腰 尚久, 本郷 道生, 粕川 雄司, 石川 慶紀, 工藤 大輔, 尾野 祐一, 飯田 純平, 佐藤 千晶, 島田 洋一
東北整形災害外科学会雑誌 ( 東北整形災害外科学会 ) 62 ( 1 ) 12 - 15 2019年06月
研究論文（学術雑誌）
健常成人男性14名を対象とし、5つの姿勢(腹臥位、立位中間位、立位前屈位、立位後屈位、座位)で腰部多裂筋の弾性度を測定し比較した。結果、各姿勢の弾性度(m/s)は腹臥位1.04±0.13、立位中間位1.53±0.34、立位前屈位2.19±0.64、立位後屈位1.54±0.55、座位1.36±0.49となり、立位前屈位は他の4姿勢に比べて有意に高値、立位中間位と立位後屈位は腹臥位に比べて有意に高値であった。各姿勢の弾性度とBMIとの相関関係について解析した結果、立位前屈位と立位後屈位でBMIと有意な正の相関が認められた。
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Miyakoshi N.
Journal of Bone and Mineral Metabolism ( Journal of Bone and Mineral Metabolism ) 37 ( 3 ) 411 - 418 2019年05月
研究論文（学術雑誌）
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Quantitative measurements of hip abduction strength in lumbar surgery patients
Hatakeyama Y.
Journal of Orthopaedic Science ( Journal of Orthopaedic Science ) 24 ( 3 ) 400 - 403 2019年05月
研究論文（学術雑誌）
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Kinoshita H.
BMC Surgery ( BMC Surgery ) 19 ( 1 ) 2019年04月
研究論文（学術雑誌）
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特集 傍脊柱筋の機能解剖学,姿勢制御と手術アプローチ 第1章 解剖と機能 胸椎前方・側方の筋肉の解剖と機能
本郷 道生, 島田 洋一, 宮腰 尚久
脊椎脊髄ジャーナル ( 三輪書店 ) 32 ( 4 ) 279 - 283 2019年04月
研究論文（学術雑誌）
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特集 脊椎脊髄外科の最近の進歩 Ⅰ.脊椎アライメント/画像診断 脊柱骨盤アライメントとQOL
本郷 道生, 宮腰 尚久, 島田 洋一
整形・災害外科 ( 金原出版 ) 62 ( 5 ) 437 - 442 2019年04月
研究論文（学術雑誌）
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症例 関節エコーが有用であった足部発症関節リウマチの3例
河野 哲也, 柏倉 剛, 相澤 俊朗, 宮腰 尚久, 島田 洋一
整形・災害外科 ( 金原出版 ) 62 ( 4 ) 431 - 434 2019年04月
研究論文（学術雑誌）
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Horikawa A.
Medicine (United States) ( Medicine (United States) ) 98 ( 6 ) 2019年02月
研究論文（学術雑誌）
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Hirota R.
Spine ( Spine ) 44 ( 4 ) E211 - E218 2019年02月
研究論文（学術雑誌）
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臨床室 近位指節間関節開放性脱臼から指壊死を生じたAeromonas hydrophila感染症の1例
成田 裕一郎, 千馬 誠悦, 佐々木 香奈, 杉村 祐介, 島田 洋一, 宮腰 尚久
整形外科 ( 南江堂 ) 70 ( 2 ) 141 - 144 2019年02月
研究論文（学術雑誌）
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Tomite T.
Journal of Orthopaedics ( Journal of Orthopaedics ) 16 ( 1 ) 25 - 30 2019年01月
研究論文（学術雑誌）
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論説 大腿骨近位部骨折例における術前移動能力と骨粗鬆症関連パラメータの関連性
湯浅 悠介, 宮腰 尚久, 粕川 雄司, 木村 善明, 柏倉 剛, 永澤 博幸, 若林 育子, 野坂 光司, 土江 博幸, 島田 洋一
整形外科 ( 南江堂 ) 70 ( 1 ) 1 - 3 2019年01月
研究論文（学術雑誌）
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65歳以上の関節リウマチ患者に対するトシリズマブ治療の有効性と安全性 〜AORAレジストリーでの調査〜
浦山 雅和, 岩本 陽輔, 阿部 秀一, 鈴木 紀夫, 加茂 啓志, 杉村 祐介, 河野 哲也, 宮腰 尚久, 島田 洋一, 秋田整形外科リウマチグループ（AORA）, 青沼 宏, 柏倉 剛, 小西 奈津雄, 伊藤 博紀, 小林 志, 櫻場 乾, 谷 貴行, 相澤 俊朗
臨床リウマチ ( 一般社団法人 日本臨床リウマチ学会 ) 31 ( 3 ) 217 - 223 2019年
研究論文（学術雑誌）
<p>目的：秋田整形外科リウマチグループ（Akita Orthopedic Group on Rheumatoid Arthritis: AORA）レジストリーにおける65歳以上の関節リウマチ（rheumatoid arthritis: RA）患者に対するトシリズマブ（tocilizumab: TCZ）治療の臨床的有効性と安全性を検討する．</p><p>対象・方法：TCZ投与累積症例177例のうち，2016年7月までに投与を開始した149例を対象とした．65歳以上の高齢者群，65歳未満の若年者群における，投与開始時の患者背景，投与継続率，disease activity score（DAS）28-ESR（4），EULAR改善基準，及び投与脱落症例を後ろ向きに調査した．</p><p>結果：高齢者群は47例（31%），若年者群は102例（69%）であった．投与開始時の患者背景では，高齢者群で，Class分類の3+4の占める割合と，MTXの非併用例が有意に多かった．投与累積継続率は，高齢者群は1年で91%，3年で82%，若年者群は1年で93%，3年で80%で，有意差はなかった．DAS28-ESR（4）は，投与開始時，高齢者群が平均4.55，若年者群が平均4.73であったが，投与後24週時には，それぞれ2.53，2.49で，両群とも有意に低下し，52週時まで維持され，両群間に有意差はなかった．疾患活動性は，52週時に高齢者群で74%，若年者群で72%が低疾患活動性を達成した．EULAR改善基準は，52週時で両群ともに87%において有効であった．投与脱落例は，有害事象は，高齢者群5例，若年者群15例，効果不十分は，高齢者群3例，若年者群9例であった．</p><p>結論：65歳以上のRA患者に対するTCZ治療の，臨床的有効性や安全性は，若年者と同等であり，TCZは高齢RA患者に有用である．</p>
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AORA（Akita Orthopedic Group on Rheumatoid Arthritis） registry 2017におけるステロイド性骨粗鬆症の治療現状
河野 哲也, 柏倉 剛, 相澤 俊朗, 宮腰 尚久, 島田 洋一
東日本整形災害外科学会雑誌 ( 東日本整形災害外科学会 ) 31 ( 2 ) 171 - 176 2019年
研究論文（学術雑誌）
<p>AORA registry 2017におけるステロイド性骨粗鬆症（GIO）の治療現状について調査した．全体の約3割の患者が治療対象であり，そのうち67.2％の患者に何らかの骨粗鬆症治療が行われていた．GIO非治療群は有意に平均年齢が低く，男性の割合が有意に高かった．また，男性は女性よりも有意に治療率が低かった．今後は，未治療の患者を減らす検討が必要と考えられた．</p>
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若林 玲奈, 宮腰 尚久, 土江 博幸, 永澤 博幸, 島田 洋一
東日本整形災害外科学会雑誌 ( 東日本整形災害外科学会 ) 31 ( 4 ) 483 - 486 2019年
研究論文（学術雑誌）
<p>BCG接種後の副反応に関してはさまざまな報告がある．今回BCG接種後に右肋骨骨髄炎を生じた症例を報告する．症例は1歳9ヵ月，男児．生後5ヵ月でBCGを接種し，1歳8ヵ月で右前胸部の腫瘤を触知した．切開生検による病理組織学的検査にて，乾酪壊死と多核巨細胞の出現を伴う類上皮細胞肉芽腫を認め，BCG接種後骨髄炎と診断した．イソニアジドとリファンピシンを内服することにより治癒している．</p>
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Early Lymph Node Metastasis May Predict Poor Prognosis in Soft Tissue Sarcoma
Emori M.
International Journal of Surgical Oncology ( International Journal of Surgical Oncology ) 2019 2019年
研究論文（学術雑誌）
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Impact of acridine orange in patients with soft tissue sarcoma treated with marginal resection
Tsuchie H.
Anticancer Research ( Anticancer Research ) 39 ( 11 ) 6365 - 6372 2019年
研究論文（学術雑誌）
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Impact of spinal kyphosis on gastric myoelectrical activity in elderly patients with osteoporosis
Tsuchie H.
Biomedical Research (Japan) ( Biomedical Research (Japan) ) 40 ( 6 ) 215 - 223 2019年
研究論文（学術雑誌）
<p>An association between spinal kyphosis and gastroesophageal reflux disease (GERD) was reported in recent years. However, it remains unclear whether spinal kyphosis affects gastric motility. We evaluated the changes in myoelectrical activity measured by electrogastrography (EGG) in elderly osteoporosis patients. A total of 18 patients scheduled for the treatment of osteoporosis were included in this study. They were analyzed by recording EGG to assess myoelectrical activity and heart rate variability (HRV) to evaluate the autonomic nervous system function before and after meals. Dominant power (DP) representing the strength of gastric electrical activity and dominant frequency (DF) representing its frequency were analyzed in blocks with a 5-minute duration. We divided the patients into 2 groups, thoracolumbar kyphosis (TLK) and non-TLK groups, and compared them. There were no significant differences between the 2 groups in background data. In the non-TLK group, DPs post 0–5 min were significantly higher than those during pre 5–0 min in channels 1 and 3 (<i>P</i> < 0.05 and <i>P</i> < 0.01). DF deviation in the TLK group was significantly higher than that in the non-TLK group at 10 to 15 postprandial minutes (<i>P</i> < 0.05). Low frequency/high frequency activity measured by HRV, reflecting the activity of the sympathetic nervous system, in the TLK group was significantly lower than that in the non-TLK group while eating (<i>P</i> < 0.01). The EGG of patients with spinal kyphotic deformity showed a similar change to that of patients with GERD; the spinal kyphotic deformity itself may affect gastric electrical activity.</p>
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Tani T.
Advances in Orthopedics ( Advances in Orthopedics ) 2019 2019年
研究論文（学術雑誌）
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Kasukawa Y.
Clinical Interventions in Aging ( Clinical Interventions in Aging ) 14 1399 - 1405 2019年
研究論文（学術雑誌）
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Ono Y.
Biomedical Research (Japan) ( Biomedical Research (Japan) ) 40 ( 5 ) 197 - 205 2019年
研究論文（学術雑誌）
<p>We investigated the effects of ibandronate, a bisphosphonate; eldecalcitol, an active vitamin D3 analogue; and combination treatment with both agents on secondary osteoporosis and arthritis using rats with adjuvant-induced arthritis. Arthritis was induced in 8-week-old male Lewis rats. Rats were randomized into four treatment groups and an untreated normal control group: ibandronate, eldecalcitol, ibandronate + eldecalcitol, vehicle, and control. Paw thickness was measured to evaluate arthritis. Joint destruction was evaluated histomorphometrically by the ankle joint stained with Fast Green and safranin O. The femur and lumbar spine were scanned using dual-energy X-ray absorptiometry, and the distal femur was scanned using micro-computed tomography for bone mineral density (BMD) and trabecular microstructural evaluations. Ibandronate and/or eldecalcitol increased BMD in both the lumbar vertebrae and femur and improved several microstructural parameters (bone volume/total volume, structure model index, trabecular number, and trabecular separation of the distal femur). In addition, there was an additive effect of combination treatment compared with single treatments for most trabecular parameters, including BMD and bone volume. However, ibandronate and/or eldecalcitol did not inhibit arthritis and joint destruction. Combination treatment with ibandronate and eldecalcitol may be effective for secondary osteoporosis associated with arthritis.</p>
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Prognostic impact of CD44 expression in patients with myxofibrosarcoma
Tsuchie H.
In Vivo ( In Vivo ) 33 ( 6 ) 2095 - 2102 2019年
研究論文（学術雑誌）
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Kasukawa Y.
Asian Spine Journal ( Asian Spine Journal ) 13 ( 5 ) 832 - 841 2019年
研究論文（学術雑誌）
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Kamo K.
Advances in Orthopedics ( Advances in Orthopedics ) 2019 2019年
研究論文（学術雑誌）
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脊髄損傷患者に対する最新のリハビリテーション治療:―機能的電気刺激（functional electrical stimulation：FES）―
松永 俊樹, 宮腰 尚久, 工藤 大輔, 斉藤 公男, 木村 竜太, 井上 純一, 千田 聡明, 畠山 和利, 島田 洋一
The Japanese journal of rehabilitation medicine = リハビリテーション医学 ( 公益社団法人 日本リハビリテーション医学会 ) 56 ( 7 ) 555 - 559 2019年
研究論文（学術雑誌）
<p>脊髄損傷による四肢麻痺・対麻痺では，脳からの運動制御指令が損傷高位で途絶するため末梢に伝達されず，随意的筋収縮ができない状態であることが多い．機能的電気刺激（FES）は，プログラムされた動作刺激を末梢運動神経とその支配筋に行う医用工学的技術で，麻痺からの回復促進や動作再建などに有用である．FESにより，四肢麻痺上肢の手指把持動作再建や，対麻痺起立歩行再建などが可能であり，新しい表面電極FESシステムが国内で普及しつつある．将来的には，多チャンネル同時刺激可能な完全埋め込み電極の実用化，BMIやリハビリテーションロボット技術の発展などと相まって，FESは脊髄損傷再生医療におけるリハビリテーション治療において，重要な役割を担うことが期待される．</p>
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三田 基樹, 宮腰 尚久, 土江 博幸, 島田 洋一
東日本整形災害外科学会雑誌 ( 東日本整形災害外科学会 ) 31 ( 4 ) 468 - 472 2019年
研究論文（学術雑誌）
<p>リンパ管腫症は小児慢性特定疾患に登録されているまれな疾患であり，治療法も確立されていない．今回われわれは，リンパ管腫症に頚椎の病的骨折を伴った1例を経験した．症例は17歳，野球練習中のスライディングを契機に受傷した．頚椎カラーによる保存加療で骨癒合を得ることが可能であり，症状の再燃も認めていない．しかしながら，今後も頚椎後弯や神経症状出現の有無について注意深い経過観察が必要である．</p>
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宮腰 尚久
The Japanese journal of rehabilitation medicine = リハビリテーション医学 ( 公益社団法人 日本リハビリテーション医学会 ) 56 ( 5 ) 367 - 370 2019年
研究論文（学術雑誌）
<p>骨粗鬆症患者において，四肢の骨折予防には，転倒予防のためのバランス訓練や下肢の筋力訓練を主体とする運動が有効であり，椎体骨折の予防には，背筋力を維持・強化する運動が有効であると考えられる．ただし，これまでの研究によれば，これらの運動療法による骨折の一次予防に対するエビデンスは明らかであるが，二次予防に対するエビデンスは非常に少ない．運動療法は，簡便なものが普及しやすいが，効果を重視した包括的な運動プログラムも考案されている．運動療法は，身体運動機能が衰える前の段階から，予防的に導入するのが望ましい．</p>
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麻痺側の大腿骨頚部骨折への人工骨頭置換術後脱臼にdual mobility cupでの人工股関節全置換術を行った1例
三浦 隆徳, 谷 貴行, 木島 泰明, 蝦名 寿仁, 宮腰 尚久, 島田 洋一
東日本整形災害外科学会雑誌 ( 東日本整形災害外科学会 ) 31 ( 1 ) 66 - 69 2019年
研究論文（学術雑誌）
<p>77歳，男性．脳出血による左不全麻痺の既往があり，転倒して左大腿骨頚部骨折を受傷した．受傷5日目に人工骨頭置換術を行ったが，麻痺側のため術後8週で人工骨頭脱臼を起こした．dual mobility cupで人工股関節全置換術を行い，再脱臼なく杖歩行可能である．同治療は脱臼リスクの高い症例への選択肢の一つになると考えられる．</p>
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Posterior spinal fusion using a unilateral C1 posterior arch screw and a C2 laminar screw for atlantoaxial fracture dislocation.
Yuichi Ono, Naohisa Miyakoshi, Michio Hongo, Yuji Kasukawa, Yoshinori Ishikawa, Daisuke Kudo, Ryota Kimura, Jumpei Iida, Yoichi Shimada
SAGE open medical case reports 7 2050313X19849276 2019年
研究論文（学術雑誌）
INTRODUCTION: C1 lateral mass screws and C2 pedicle screws are usually chosen to fix atlantoaxial (C1-C2) instability. However, there are a few situations in which these screws are difficult to use, such as in a case with a fracture line at the screw insertion point and bleeding from the fracture site. A new technique using a unilateral C1 posterior arch screw and a C2 laminar screw combined with a contralateral C1 lateral mass screws-C2 pedicle screws procedure for upper cervical fixation is reported. CASE REPORT: A 24-year-old woman had an irreducible C1-C2 anterior dislocation with a type III odontoid fracture on the right side due to a traffic accident. The patient underwent open reduction and posterior C1-C2 fixation. On the left side, a C1 lateral mass screws and a C2 pedicle screws were placed. Because there was bleeding from the fracture site and a high-riding vertebral artery was seen on the right side, a C1 posterior arch screw and a C2 laminar screw were chosen. Eight months after the surgery, computed tomography scans showed healing of the odontoid fracture with anatomically correct alignment. CONCLUSIONS: Although there have been few comparable studies, fixation with unilateral C1 posterior arch screw-C2 laminar screw could be a beneficial choice for surgeries involving the upper cervical region in patients with fracture dislocation or arterial abnormalities.
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Age-related prevalence of periodontoid calcification and its associations with acute cervical pain
Kobayashi T.
Asian Spine Journal ( Asian Spine Journal ) 12 ( 6 ) 1117 - 1122 2018年12月
研究論文（学術雑誌）
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Tsuchie H.
Osteoporosis International ( Osteoporosis International ) 29 ( 12 ) 2659 - 2665 2018年12月
研究論文（学術雑誌）
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Saito H.
Knee Surgery and Related Research ( Knee Surgery and Related Research ) 30 ( 4 ) 293 - 302 2018年12月
研究論文（学術雑誌）
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Traumatic intratumoral hemorrhage of schwannoma of the cauda equina: A report of two cases
Kimura R.
Journal of Orthopaedic Science ( Journal of Orthopaedic Science ) 23 ( 6 ) 1105 - 1109 2018年11月
研究論文（学術雑誌）
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Akagawa M.
PLoS ONE ( PLoS ONE ) 13 ( 10 ) e0204857 2018年10月
研究論文（学術雑誌）
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しびれ・痛みに対する整形外科診療の進歩 Ⅱ.疾患・病態別の診断・治療 4.下肢 下肢に生じた脆弱性骨折に対するIlizarov創外固定と低出力超音波骨折治療器,テリパラチドの併用による早期疼痛減少効果
野坂 光司, 宮腰 尚久, 粕川 雄司, 齊藤 英知, 土江 博幸, 島田 洋一
別冊整形外科 ( 南江堂 ) 1 ( 74 ) 179 - 184 2018年10月
研究論文（学術雑誌）
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Suzuki N.
Journal of Orthopaedic Science ( Journal of Orthopaedic Science ) 23 ( 5 ) 849 - 852 2018年09月
研究論文（学術雑誌）
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Tsuchie H.
International Journal of Clinical Oncology ( International Journal of Clinical Oncology ) 23 ( 4 ) 775 - 782 2018年08月
研究論文（学術雑誌）
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Miyakoshi N.
BMC Surgery ( BMC Surgery ) 18 ( 1 ) 38 2018年06月
研究論文（学術雑誌）
Background: Safe excision of spinal cord tumors depends on sufficient visualization of the tumor and surrounding structures. In patients with spinal cord tumor adjacent to a stenotic spinal canal, extensive bony decompression proximal and distal to the tumor should be considered for safer excision of the tumor. Extensive wide laminectomy is one choice for such cases, but postoperative problems such as kyphotic deformity remain a concern. Case presentation: A 76-year-old man and a 60-year-old woman presented with symptomatic intradural extramedullary spinal cord tumors in the cervical spine. Both patients showed a combination of spondylotic changes in the cervical spine and stenotic condition at the level of the tumor. Both tumors were successfully resected through open-door laminoplasty with hydroxyapatite (HA) spacers, with the tumor located on the side of the laminoplasty. Histological diagnosis was schwannoma for both tumors. HA spacers completely bonded to the host bone and did not interfere with postoperative magnetic resonance imaging (MRI) of the inside of the spinal canal. Cervical spine alignment was maintained at the final follow-up of 6 years in both cases. Conclusion: Laminoplasty with HA spacers enabled successful tumor extirpation, reliable MRI follow-up after surgery, and maintenance of normal cervical spine alignment. Laminoplasty with HA spacers represents a good option for the treatment of cervical spinal cord tumor in patients combined with spinal stenosis.
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Kasukawa Y.
Pain Practice ( Pain Practice ) 18 ( 5 ) 625 - 630 2018年06月
研究論文（学術雑誌）
Purpose: We aimed to evaluate the incidence of (and risk factors for) postoperative pregabalin and/or limaprost to treat persistent numbness and/or pain of the lower extremities after lumbar spinal stenosis (LSS) surgery. Methods: Medical records of 329 patients (168 men, 161 women
average age 70 years) were retrospectively reviewed for data on the duration of LSS diagnosis
LSS disease
preoperative medication (limaprost, pregabalin, or combined limaprost/pregabalin
duration)
symptoms
preoperative/postoperative intermittent claudication (IC)
operation type
and postoperative medication and period. Results: Limaprost, pregabalin, and combined limaprost/pregabalin were prescribed preoperatively for 43%, 7%, and 5% of patients, respectively. At an average of 21 months postoperatively, limaprost, pregabalin, and combined therapy were prescribed in 11%, 8%, 4% of patients, respectively. Medication requirement was significantly lower postoperatively than preoperatively (P <
0.0001). Significant risk factors for required postoperative medication were required preoperative medication (odds ratio [OR] 3.088, 95% confidence interval [CI] 1.679 to 5.681]
postoperative period (OR 1.063, 95% CI 1.031 to 1.096)
and postoperative IC (OR 3.868, 95% CI 1.481 to 10.103). A negative impact from postoperative medication was seen in patients who had undergone decompression surgery (OR 0.589, 95% CI 0.377 to 0.918). Conclusions: Overall, 23% of LSS patients required medication for pain and/or numbness at 21 months postoperatively. Significant factors portending required postoperative medication were preoperative medication, longer postoperative period, and postoperative IC. A negative influence from postoperative medication was seen in patients who had undergone decompression surgery without fusion. -
Reconstruction of a chronically ruptured Achilles tendon using an internal brace: A case report
Chida S.
Journal of Medical Case Reports ( Journal of Medical Case Reports ) 12 ( 1 ) 54 2018年03月
研究論文（学術雑誌）
Background: We reconstructed a chronically ruptured Achilles tendon and the associated scar tissue using braided polyblend polyethylene sutures (FiberWire
Arthrex Inc.
Naples, FL, USA) and anchors. Case presentation: A 68-year-old Japanese man, who was being treated for right Achilles tendinosis, felt pain in his Achilles tendon when walking and started to find plantar flexion of his ankle joint difficult. As his symptoms persisted, he visited us after 4 weeks. Surgery and orthotic therapy were recommended, but he did not want to undergo these treatments. However, he began to find walking difficult and so underwent surgery 6 months after suffering the injury. The interior of the tendon was curetted, and the ruptured region was subjected to plication using the surrounding scar tissue. Using the percutaneous Achilles repair system (Arthrex Inc.), FiberWire sutures were inserted, and two skin incisions were made on the medial and lateral sides of his calcaneus in the region surrounding the Achilles tendon attachment. SutureLasso (Arthrex Inc.) was passed through, and the proximal FiberWire suture was relayed and fixed with 4.75-mm SwiveLock (Arthrex Inc.). After surgery, his foot was fixed in plaster at 20° plantar flexion of his ankle joint. The plaster was removed 1 week after surgery, and after-treatment was initiated with active dorsiflexion training. No orthosis was used after surgery. As of 16 postoperative months, no re-rupture had occurred. Conclusions: This method might allow post-treatment rehabilitation, and so on, to occur earlier, and, hence, could become an option for the reconstruction of chronically ruptured Achilles tendons. -
Kijima H.
HIP International ( HIP International ) 28 ( 2 ) 145 - 147 2018年03月
研究論文（学術雑誌）
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特集 創外固定でなければできない治療 脆弱性骨折における創外固定の有用性
野坂 光司, 宮腰 尚久, 齊藤 英知, 木島 泰明, 土江 博幸, 島田 洋一
整形・災害外科 ( 金原出版 ) 61 ( 2 ) 191 - 198 2018年02月
研究論文（学術雑誌）
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特集 すべてわかる 足・足関節外科で用いられる最新デバイスカタログ 足・足関節に対するリング型創外固定器の各種比較
野坂 光司, 宮腰 尚久, 齊藤 英知, 木島 泰明, 土江 博幸, 斉藤 公男, 柴田 暢介, 島田 洋一
関節外科 ( (株)メジカルビュー社 ) 37 ( 1 ) 97 - 106 2018年01月
研究論文（学術雑誌）
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経験と考察 脳性麻痺児における足部変形の成因と治療に関する検討
河野 哲也, 坂本 仁, 三澤 晶子, 石原 芳人, 遠藤 博之, 宮腰 尚久, 島田 洋一
整形外科 ( 南江堂 ) 69 ( 1 ) 17 - 21 2018年01月
研究論文（学術雑誌）
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Ahlbäck分類4-5の内側型変形性膝関節症に対する膝周囲骨切り術とtotal knee arthroplastyの短期臨床成績の比較
齊藤 英知, 斉藤 公男, 島田 洋一, 赤川 学, 塚本 泰朗, 宮腰 尚久
東日本整形災害外科学会雑誌 ( 東日本整形災害外科学会 ) 30 ( 2 ) 155 - 163 2018年
研究論文（学術雑誌）
<p>生理的関節面傾斜を再獲得できるdouble level osteotomy（DLO）や沈下した脛骨内側プラトー（MTP）を矯正する脛骨顆外反骨切り術（TCVO）により，進行した内側型変形性膝関節症（膝OA）でも生理的関節面傾斜を再獲得できる．本研究の目的は，Ahlbäck分類4-5の膝OAに対する膝周囲骨切り術（around the knee osteotomy, AKO）とTotal Knee Arthroplasty（TKA）の観察期間22.4ヵ月における短期臨床成績を比較すること．対象は36膝で，AKO群（14膝）とTKA（22膝）の臨床スコアを比較した．new knee society scoreでは，活動性と応用動作でAKO群が，Knee Injury and Osteoarthritis Outcome Score（KOOS）の痛みで，TKA群で有意に高値であった．</p>
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Analgesic effects of minodronate in a rat chronic pain model
Kasukawa Y.
Biomedical Research (Japan) ( Biomedical Research (Japan) ) 39 ( 5 ) 261 - 268 2018年
研究論文（学術雑誌）
<p>We evaluated the analgesic effects of minodronate, alendronate and pregabalin on mechanical and thermal allodynia, as well as changes in bone mineral density and skeletal muscle volume caused by chronic constriction injury (CCI) in an ovariectomized rat. Ovariectomy was performed on four-week-old female Wistar rats. Thereafter, at 8-weeks of age, the left sciatic nerve was ligated to create the chronic pain model (CCI limb), and sham surgery was performed on the right hindlimb. In all rats, either minodronate (0.15 mg/kg/week), alendronate (0.15 mg/kg/week), pregabalin (10 mg/kg/week), or their vehicle was administered for 2 weeks starting on the 0th day of CCI. Behavioral evaluations, with von Frey testing and the hot plate test, were performed on days 0, 7 and 14. After 2 weeks, bilateral femurs and tibialis anterior muscles were harvested for bone mineral density and cross sectional area measurements, respectively. Two weeks treatment with minodronate significantly improved mechanical and thermal allodynia evaluated by the von Frey and hot plate tests in the CCI limb (<i>P</i> < 0.05). Minodronate and alendronate treatment for 2 weeks significantly increased total femoral bone mineral density in the CCI limb compared with pregabalin or vehicle treatment (<i>P</i> < 0.01). Cross sectional area of the CCI limb in the minodronate group was significantly larger than that of the alendronate group (<i>P</i> < 0.05) and pregabalin group (<i>P</i> < 0.05). Two-week treatment with minodronate, but not alendronate or pregabalin, improved mechanical and thermal allodynia caused by CCI in ovariectomized rats.</p>
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AORAレジストリーにおける関節リウマチに対するトシリズマブ治療の効果不十分による脱落症例の検討
浦山 雅和, 阿部 秀一, 加茂 啓志, 杉村 祐介, 宮腰 尚久, 島田 洋一, 秋田整形外科リウマチグループ（AORA）, 青沼 宏, 柏倉 剛, 伊藤 博紀, 小林 志, 櫻場 乾, 谷 貴行, 相澤 俊朗, 河野 哲也
臨床リウマチ ( 一般社団法人 日本臨床リウマチ学会 ) 30 ( 2 ) 114 - 119 2018年
研究論文（学術雑誌）
<p>目的：秋田整形外科リウマチグループ（Akita Orthopedic group on Rheumatoid Arthritis: AORA）レジストリーにおける，関節リウマチ（rheumatoid arthritis, RA）に対するトシリズマブ（tocilizumab, TCZ）治療の効果不十分による脱落症例を調査し，本薬剤の有用な使用の可能性を検討する．対象・方法：TCZ使用累積症例177例，ナイーブ群（N群）95例，スイッチ群（S群）82例を対象とした．患者背景，脱落までの使用期間，脱落後の治療，疾患活動性を後ろ向きに調査した．結果：効果不十分による脱落症例は12例（７%）であった．平均58歳（44～82歳）で，罹病期間は平均120ヵ月（６～366ヵ月）であった．N群が４例，S群が８例で，全てTNF (tumor necrosis factor)阻害薬からのスイッチであった．TCZ使用開始から脱落までの期間は平均30ヵ月（６～67ヵ月）であった．脱落後に他の生物学的製剤にスイッチした症例は10例で，TNF阻害薬が２例，abatacept（ABT）が８例であった．最終調査時，S群かつABTにスイッチした３例がさらにTNF阻害薬にスイッチした．CDAIは，使用開始時が平均±標準偏差20.3±13.4で，脱落時は12.4±8.1であり，６例は低疾患活動性を達成した．最終調査時は9.5±8.4で，８例は低疾患活動性を達成した．結論：効果不十分による脱落症例は，TNF阻害薬からのスイッチ症例が多かった.脱落後のスイッチは，TNF阻害薬，ABTともに有用であった．総合的な効果不十分の判断により，TCZの有用な使用継続の可能性がある．</p>
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Comparison of Atypical and Osteoporotic Femoral Shaft Fractures in the Elderly: A Multicenter Study
Miura T.
Advances in Orthopedics ( Advances in Orthopedics ) 2018 1068053 2018年
研究論文（学術雑誌）
Background. In atypical femoral fractures, owing to the high rates of complications and delayed healing that accompany the plate fixation, the most favorable treatment is intramedullary nailing. Although there is insufficient evidence, plate fixation is chosen due to anterolateral bowing of the femur. This study compared the bone healing time and rates of complications in atypical femoral shaft fractures and osteoporotic femoral shaft fractures. Methods. We searched the medical records of 3 institutions in Japan for patients with femoral shaft fractures who visited between 1 January 2010 and 31 December 2015. We identified 65 patients and excluded 37 among these due to high-energy injuries or being younger than 65 years. Among the remaining patients, we identified 17 and 11 women with atypical (AFF group) and osteoporotic femoral shaft fractures (OP group), respectively. Results. In surgical method, there were differences in intramedullary nailing (94.1% versus 27.2%) (p <
0.01). The mean bone healing time was 11.1 months versus 6.7 months in 2 groups (p <
0.01). Iatrogenic femoral fractures during intramedullary nail insertion were observed in both groups, and reoperation was only seen in atypical femoral fractures treated with a plate fixation, but there was no difference in the rate of complications (23.5% versus 9.1%). Conclusions. In the atypical femoral fracture group, intramedullary nailing was more chosen, but the bone healing time was delayed and plate fixation cases needed reoperation. There was no significant difference in the rate of complications between the 2 groups. -
Kimura Ryota, Shimada Yoichi, Matsunaga Toshiki, Iwami Takehiro, Kudo Daisuke, Saitoh Kimio, Hatakeyama Kazutoshi, Watanabe Motoyuki, Takahashi Yusuke, Miyakoshi Naohisa
Progress in Rehabilitation Medicine ( 公益社団法人 日本リハビリテーション医学会 ) 3 ( 0 ) 2018年
研究論文（学術雑誌）
<p><b>Objective:</b> We developed a rehabilitation robot to assist hemiplegics with gait exercises. The robot was combined with functional electrical stimulation (FES) of the affected side and was controlled by a real-time-feedback system that attempted to replicate the lower extremity movements of the non-affected limb on the affected side. We measured the reproducibility of the non-affected limb movements on the affected side using FES in non-disabled individuals and evaluated the smoothness of the resulting motion. <b>Method:</b> Ten healthy men participated in this study. The left side was defined as the non-affected side. The measured hip and knee joint angles of the non-affected side were reproduced on the pseudo-paralytic side using the robot's motors. The right quadriceps was stimulated with FES. Joint angles were measured with a motion capture system. We assessed the reproducibility of the amplitude from the maximum angle of flexion to extension during the walking cycle. The smoothness of the motion was evaluated using the angular jerk cost (AJC). <b>Results:</b> The amplitude reproduction (%) was 87.9 ± 6.2 (mean ± standard deviation) and 71.5 ± 10.7 for the hip and knee joints, respectively. The walking cycle reproduction rate was 99.9 ± 0.1 and 99.8 ± 0.2 for the hip and knee joints, respectively. There were no statistically significant differences between results with FES versus those without FES. The AJC of the robot side was significantly smaller than that of the non-affected side. <b>Conclusions:</b> A master–slave gait rehabilitation system has not previously been attempted in hemiplegic patients. Our rehabilitation robot showed high reproducibility of motion on the affected side.</p>
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hybrid closed wedge high tibial osteotomyのアプローチ法による前脛骨筋に対する侵襲性の検討
赤川 学, 齊藤 英知, 斉藤 公男, 佐々木 香奈, 宮腰 尚久, 島田 洋一
東日本整形災害外科学会雑誌 ( 東日本整形災害外科学会 ) 30 ( 1 ) 86 - 88 2018年
研究論文（学術雑誌）
<p>hybrid CWHTOの2つのアプローチ法（Open法，MIS法）による手術侵襲の違いを検討した．結果，Open法に比較してMIS法で有意に術後CK，CRPが高い結果だった．これらは手術侵入時の前脛骨筋の損傷を反映していると考えられた．hybrid CWHTO施行時は前脛骨筋損傷に留意する必要があると考えられる．</p>
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赤川 学, 齊藤 英知, 斉藤 公男, 塚本 泰朗, 木島 泰明, 宮腰 尚久, 島田 洋一, 佐々木 香奈
東北膝関節研究会会誌 ( 東北膝関節研究会 ) 27 ( 0 ) 17 - 22 2018年
研究論文（学術雑誌）
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Kudo D.
Clinical Interventions in Aging ( Clinical Interventions in Aging ) 13 1633 - 1638 2018年
研究論文（学術雑誌）
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Pyogenic Spondylitis Caused by Methicillin-Resistant <i>Staphylococcus aureus</i> Associated with Tracheostomy followed by Resection of Ossification of the Anterior Longitudinal Ligament.
Hongo M, Miyakoshi N, Fujii M, Kasukawa Y, Ishikawa Y, Kudo D, Shimada Y
Case reports in orthopedics 2018 9076509 2018年
研究論文（学術雑誌）
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佐々木 香奈, 島田 洋一, 片岡 洋一, 齊藤 英知, 高橋 靖博, 塚本 泰朗, 赤川 学, 藤井 昌, 斉藤 公男, 木島 泰明, 宮腰 尚久
東北膝関節研究会会誌 ( 東北膝関節研究会 ) 27 ( 0 ) 23 - 27 2018年
研究論文（学術雑誌）
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変形性膝関節症におけるbone marrow lesionsと骨強度パラメーターとの関連
藤井 昌, 木島 泰明, 齊藤 英知, 野坂 光司, 宮腰 尚久, 島田 洋一
東日本整形災害外科学会雑誌 ( 東日本整形災害外科学会 ) 30 ( 1 ) 52 - 56 2018年
研究論文（学術雑誌）
<p>変形性膝関節症（膝OA）におけるbone marrow lesions（BMLs）と骨強度パラメーターとの関連を検討した．BMLsを有する群で進行関節症の割合，DPD，Penが有意に高く，多変量解析では，KL分類 grade Ⅲ以上のOAと Pen高値がBMLs発生のリスク因子であることがわかった．骨切り術などの外科治療に加え，骨代謝に焦点を当てたテーラーメイドの薬物治療を併用することは，関節温存のための新たな治療戦略になりうると考えられた．</p>
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Cervical arachnoid cyst mimicking the cause of cervical radiculopathy: A case report
Kobayashi T.
Interdisciplinary Neurosurgery: Advanced Techniques and Case Management ( Interdisciplinary Neurosurgery: Advanced Techniques and Case Management ) 10 37 - 39 2017年12月
研究論文（学術雑誌）
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Kudo D.
European Spine Journal ( European Spine Journal ) 26 ( 12 ) 3156 - 3161 2017年12月
研究論文（学術雑誌）
Malnutrition is one of the important risk factors for postoperative complications. Transferrin, prealbumin, and retinol-binding protein, so-called rapid turnover proteins (RTPs), may be the better indicators for early detection of nutritional deficits. However, few studies have described the impact of serum RTP levels on postoperative surgical site infection (SSI) in spine surgery. The purpose of this study was to investigate the relationship between preoperative serum RTPs and postoperative SSI.
The data of 105 patients (64 male, 41 female; average age 64.4 years; age range 20-88 years) who underwent spine surgery in a single institution between 2014 and 2015 were retrospectively analyzed. Preoperative total lymphocyte count, serum albumin, transferrin, prealbumin, retinol-binding protein, pre-and postopeartive C-reactive protein (CRP), white blood cell count (WBC), and total lymphocyte count were evaluated. Postoperative CRP, WBC, and total lymphocyte count were repeated two or three times/week until hospital discharge. A broad spectrum penicillin or second generation cephalosporin was administered as a prophylactic antibiotic to each patient. When repeated CRP elevation or lymphopenia (no more than 10% or 1000/mu L) after postoperative day 3 or 4 was observed, possible SSI was diagnosed. Variables between possible SSI group and non-SSI group were compared using Mann-Whitney U or Chi square test. All variables on univariate analysis were included in multiple logistic regression analysis to identify risk factors for possible postoperative SSI.
Thirty-five patients were diagnosed with possible SSI. The mean operative time of possible SSI group was significantly longer (p = 0.036), preoperative total lymphocyte count and serum prealbumin level of possible SSI group were significantly lower (p = 0.002, p = 0.048, respectively) than that of non-SSI group. On univariate analysis, operative time (p = 0.012), preoperative total lymphocyte count (p = 0.041), serum albumin level (p = 0.038), and serum prealbumin level (p = 0.044) were significant contributors to possible SSI, and multiple logistic regression analysis revealed that operative time was the significant contributor to possible SSI (odds ratio 1.008, 95% confidence interval (CI) 1.001-1.015, p = 0.024).
A low prealbumin level is a possible risk factor for early-stage SSI in spine surgery, though it was not statistically significant; operative time was the most important indicator of SSI on multivariate analysis. -
Miyakoshi N.
Osteoporosis International ( Osteoporosis International ) 28 ( 11 ) 3153 - 3160 2017年11月
研究論文（学術雑誌）
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経験と考察 鎖骨骨折手術に対する第4頚椎神経根ブロックの有用性
木村 竜太, 宮腰 尚久, 石河 紀之, 湯本 聡, 岩本 陽輔, 島田 洋一
整形外科 ( 南江堂 ) 68 ( 12 ) 1251 - 1254 2017年11月
研究論文（学術雑誌）
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Miyakoshi N.
Asian Spine Journal ( Asian Spine Journal ) 11 ( 5 ) 756 - 762 2017年10月
研究論文（学術雑誌）
Study Design: A retrospective comparative study. Purpose: To compare perioperative medical complications after posterior approach spinal instrumentation surgery for osteoporotic vertebral collapse (OVC) between patients with primary osteoporosis and those with secondary osteoporosis. Overview of Literature: With increased aging of society, the demand for instrumentation surgery for an osteoporotic spine has been increasing. However, no studies have compared the rates or severities of perioperative complications after spinal instrumentation surgery between patients with primary osteoporosis and those with secondary osteoporosis. Methods: Ninety-one patients with OVC aged =50 years (23 males and 68 females) who underwent posterior approach vertebral replacement with cages or posterior spinal fusion combined with vertebroplasty were divided into primary (n=56) and secondary (n=35) osteoporosis groups. Bone mineral density (BMD), osteoporosis treatment prior to OVC, operative invasiveness, and perioperative medical complications were compared. Results: Diabetes mellitus (51.4%) was the most common cause of secondary osteoporosis, followed by glucocorticoid use (22.9%). No significant differences were seen in terms of age, gender, BMD, osteoporosis treatment, or operative invasiveness, including the number of levels fused, estimated blood loss, and number of patients requiring transfusion. No significant difference in the incidence of perioperative complications were observed between the primary and secondary osteoporosis groups (16.1% vs. 22.9%). However, surgical site infection (SSI) was significantly more frequently seen in the secondary osteoporosis group (11.4%) than in the primary osteoporosis group (1.8%
p <
0.05). One patient in the secondary osteoporosis group developed methicillin-resistant Staphylococcus aureus infection that ultimately required instrument removal. Conclusions: The overall incidence of perioperative medical complications after posterior approach spinal instrumentation surgery for OVC was comparable between the primary and secondary osteoporosis groups under conditions of similar background characteristics and operative invasiveness. However, SSI (particularly more severe cases) occurred more frequently in patients with secondary osteoporosis. -
特集 高齢者(75歳以上)の運動器変性疾患に対する治療 脊椎の変性疾患に対する高齢者治療 胸腰仙椎変性疾患 変形性腰椎症・腰部脊柱管狭窄症 80歳以上の高齢者に対する脊椎固定術
石川 慶紀, 宮腰 尚久, 島田 洋一
別冊整形外科 ( (株)南江堂 ) 1 ( 72 ) 97 - 99 2017年10月
研究論文（学術雑誌）
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特集 高齢者脊椎疾患の診断・治療の最近の進歩 骨粗鬆症性 骨粗鬆症と腰背部痛・脊柱変形・サルコペニア
宮腰 尚久
関節外科 ( (株)メジカルビュー社 ) 36 ( 14 ) 90 - 97 2017年10月
研究論文（学術雑誌）
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Sasaki K.
Asian Spine Journal ( Asian Spine Journal ) 11 ( 4 ) 562 - 569 2017年08月
研究論文（学術雑誌）
Study Design: In vivo biomechanical study using a three-dimensional (3D) musculoskeletal model for elderly individuals with or without pelvic retroversion. Purpose: To evaluate the effect of pelvic retroversion on the sagittal alignment of the spine, pelvis, and lower limb in elderly females while standing and walking. Overview of Literature: Patients with hip-spine syndrome have concurrent hip-joint and spine diseases. However, the dynamic sagittal alignment between the hip joint and spine has rarely been investigated. We used a 3D musculoskeletal model to evaluate global spinopelvic parameters, including spinal inclination and pelvic tilt (PT). Methods: A total of 32 ambulant females (mean age=78 years) without assistance were enrolled in the study. On the basis of the radiographic measurement for PT, participants were divided into the pelvic retroversion group (R-group
PT=20°) and the normal group (N-group
PT <
20°). A 3D musculoskeletal motion analysis system was used to analyze the calculated value for the alignment of spine, pelvis, and lower limb, including calculated (C)-PT, sagittal vertical axis (C-SVA), pelvic incidence, lumbar lordosis, T1 pelvic angle (CTPA), as well as knee and hip flexion angles while standing and walking. Results: While standing, C-PT and C-TPA in the R-group were significantly larger than those in the N-group. Hip angle was significantly smaller in the R-group than in the N-group, unlike knee angle, which did not show difference. While walking, C-SVA and C-TPA were significantly increased, whereas C-PT decreased compared with those while standing. The maximum hip-flexion angle was significantly smaller in the R-group than in the N-group. There was a significant correlation between the radiographic and calculated parameters. Conclusions: The 3D musculoskeletal model was useful in evaluating the sagittal alignment of the spine, pelvis, and leg. Spinopelvic sagittal alignment showed deterioration while walking. C-PT was significantly decreased while walking in the R-group, indicating possible compensatory mechanisms attempting to increase coverage of the femoral head. The reduction in the hip flexion angle in the R-group was also considered as a compensatory mechanism. -
誌上シンポジウム 創外固定でどこまでできるか? リング型創外固定による外傷治療
野坂 光司, 宮腰 尚久, 山田 晋, 齊藤 英知, 木島 泰明, 土江 博幸, 斉藤 公男, 島田 洋一
臨床整形外科 ( 株式会社医学書院 ) 52 ( 8 ) 713 - 717 2017年08月
研究論文（学術雑誌）
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Kinoshita H.
Modern Rheumatology ( Modern Rheumatology ) 27 ( 4 ) 582 - 586 2017年07月
研究論文（学術雑誌）
Objectives: This study aimed to investigate the efficacy of denosumab (compared with that of bisphosphonates) for preventing secondary osteoporosis and inflammation caused by excessive bone resorption in Japanese rheumatoid arthritis (RA) patients never previously treated for osteoporosis.
Methods: Ninety-eight patients with coexisting RA and osteoporosis were enrolled. The patients were subdivided by whether they were treated with denosumab (n=49) or traditional bisphosphonates (n=49). RA disease activity, bone turnover markers, and bone mineral density (BMD) were compared between the two groups before treatment, and after 6 and 12 months of treatment.
Results: There was no significant difference between the groups in any of the disease activity indices and BMD at any of the measured time points. With regard to bone metabolism, denosumab significantly reduced bone-specific alkaline phosphatase at 6 and 12 months compared with pretreatment, but had no effect on tartrate-resistant acid phosphatase 5b levels, suggesting an effect on the bone formation rate, but not on the bone resorption rate.
Conclusions: Neither denosumab nor bisphosphonates could suppress inflammation or RA disease activity, but denosumab significantly suppressed a marker of bone metabolism in Japanese RA patients never previously treated for osteoporosis. -
Distant metastasis in patients with myxofibrosarcoma
Tsuchie H.
Upsala Journal of Medical Sciences ( Upsala Journal of Medical Sciences ) 122 ( 3 ) 190 - 193 2017年07月
研究論文（学術雑誌）
Purpose: A clinical feature of myxofibrosarcoma is local recurrence, but knowledge about distant metastasis is sparse. We evaluated the tendency of clinical and histological features of metastasis in myxofibrosarcoma patients.
Methods: Fifty-eight patients with myxofibrosarcoma were treated in our hospitals, and a total of 16 consecutive patients with distant metastases were included in this retrospective study (9 males and 7 females, with a mean age of 77 years). Because there was no patient complicated by both lung and lymph node metastases, we compared the age, sex, tumor size and location, French Federation of Cancer Centers Sarcoma Group (FNCLCC) grade, American Joint Committee on Cancer (AJCC) stage, and times of the first metastasis from the initial examination between the lung and lymph node groups. In addition, we examined factors affecting the prognosis.
Results: The median follow-up period was 42.9 months (range 8-142). Eleven of 16 patients developed pulmonary metastases. The sites of extra pulmonary metastases were the lymph nodes in 5 patients, bone in 1, subcutaneous in 1, intramuscular in 1, and peritoneum in 1. The median time for patients to develop distant metastases was 17.4 months (range 0-59). The time until the onset of the first metastasis in the lung metastasis group was significantly shorter than in the lymph node group (p < 0.05). Also, the survival rate in the lymph node metastasis group was better than in the lung metastasis group (p < 0.05).
Conclusions: Not only lung metastasis but also lymph node metastasis occurs frequently in myxofibrosarcoma patients. Myxofibrosarcoma with lung metastasis is more aggressive than the type with lymph node metastasis. -
特集 非定型大腿骨骨折の病態と治療 非定型大腿骨骨折の危険因子としての大腿骨弯曲変形の要因
土江 博幸, 宮腰 尚久, 島田 洋一
整形・災害外科 ( 金原出版 ) 60 ( 8 ) 965 - 972 2017年07月
研究論文（学術雑誌）
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特集 老化と生体恒常性 Therapy ロコモティブシンドロームに対する予防・治療
宮腰尚久
CLINICAL CALCIUM ( 医薬ジャーナル社 ) 27 ( 7 ) 105 - 112 2017年06月
研究論文（学術雑誌）
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理解を助けるトレーニング問題(本号特集「老化と生体恒常性」関連) ロコモティブシンドロームに関して
宮腰尚久
CLINICAL CALCIUM ( 医薬ジャーナル社 ) 27 ( 7 ) 116 - 116 2017年06月
研究論文（学術雑誌）
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Enhanced bone healing and decreased pain in sacral insufficiency fractures after teriparatide treatment: retrospective clinical-based observational study.
Kasukawa Y, Miyakoshi N, Ebina T, Hongo M, Ishikawa Y, Kudo D, Nozaka K, Shimada Y
Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases 14 ( 2 ) 140 - 145 2017年05月
研究論文（学術雑誌）
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特集 医工連携による新たな整形外科治療 脊椎モデルシミュレーションの臨床応用
島田 洋一, 佐々木 研, 巖見 武裕, 本郷 道生, 宮腰 尚久
関節外科 ( (株)メジカルビュー社 ) 36 ( 5 ) 534 - 540 2017年05月
研究論文（学術雑誌）
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特集 高齢者の脊柱変形Up to Date 第2章 治療 高齢者脊柱変形に対する保存療法-胸腰椎部・骨盤:運動療法
本郷 道生, 宮腰 尚久, 島田 洋一
脊椎脊髄ジャーナル ( 三輪書店 ) 30 ( 4 ) 339 - 344 2017年04月
研究論文（学術雑誌）
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骨粗鬆症マネジメントupdate 骨粗鬆症の治療 外科治療
宮腰 尚久
腎と骨代謝 ( 日本メディカルセンター ) 30 ( 2 ) 115 - 121 2017年04月
研究論文（学術雑誌）
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Ishikawa Y.
Gait and Posture ( Gait and Posture ) 53 98 - 103 2017年03月
研究論文（学術雑誌）
Spinal deformities can affect quality of life (QOL) and risk of falling, but no studies have explored the relationships of spinal mobility and sagittal alignment of spine and the lower extremities simultaneously. Purpose of this study is to clarify the relationship of those postural parameters to QOL and risk of falling. The study evaluated 110 subjects (41 men, 69 women; mean age, 73 years). Upright and flexion and extension angles for thoracic kyphosis, lumbar lordosis, and spinal inclination were evaluated with SpinalMouse. Total-body inclination and hip and knee flexion angles in upright position were measured from lateral photographs. Subjects were divided into Fallers (n= 23, 21%) and Non-fallers (n= 87, 79%) based on past history of falls. QOL was assessed using the Short Form 36 Health Survey (SF-36). Age, total-body inclination, spinal inclination upright and in extension, thoracic kyphosis in flexion, lumbar lordosis upright and in extension, and knee flexion correlated significantly with the SF-36. Multiple regression analysis revealed total-body inclination and knee flexion to have the most significant relationships with the SF-36. SF-36, total-body inclination, spinal inclination in extension, thoracic kyphosis in flexion, lumbar lordosis upright and in extension, and hip and knee flexion angles differed significantly between Fallers and Non-fallers (P<0.05 for all). Multivariate logistic regression analyses revealed lumbar lordosis in extension to be a significant predictor of falling (P= 0.038). Forward-stooped posture and knee-flexion deformity could be important indicator of lower QOL. Moreover, limited extension in the lumbar spine could be a useful screening examination for fall prevention in the elderly. (C) 2017 Elsevier B.V. All rights reserved.
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連載 注目の海外文献(60) １.椎体楔状変形の病因:２段階の経過によって生じるのか? ２.女性におけるBMIの違いによる椎体強度と推定骨折リスク ３.有痛性の急性期骨粗鬆性椎体骨折に対する椎体形成術の効果と安全性:多施設共同ランダム化二重盲検プラセボ対照試験
宮腰尚久
CLINICAL CALCIUM ( 医薬ジャーナル社 ) 27 ( 4 ) 108 - 110 2017年03月
研究論文（学術雑誌）
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Age-related changes in muscle strength and spinal kyphosis angles in an elderly Japanese population
Kasukawa Y.
Clinical Interventions in Aging ( Clinical Interventions in Aging ) 12 413 - 420 2017年02月
研究論文（学術雑誌）
Lumbar kyphosis and the decreased mobility of the lumbar spine increase the risk of falls and impair both the quality of life and the ability to perform activities of daily living. However, in the elderly Japanese population, little is known about the age-related changes and sex-related differences in muscle strength, including of the upper and lower extremities and back extensors. An adequate kyphotic or lordotic angle has also not been determined. In this study, we evaluated the age-related changes in muscle strength and spinal kyphosis in 252 males and 320 females $50 years of age. Grip, back extensor, hip flexor, and knee extensor strength
thoracic and lumbar kyphosis
and spinal inclination in the neutral standing position were assessed, together with the range of motion of the thoracic and lumbar spine and spinal inclination. Grip strength, back extensor strength, and the strength of the hip flexors and knee extensors decreased significantly with aging, both in males (P,0.0001) and in females (P=0.0015 to P,0.0001). The lumbar but not the thoracic kyphosis angle decreased significantly with aging, only in females (P,0.0001). Spinal inclination increased significantly with aging in both males (P=0.002) and females (P,0.0001). Back extensor strength and the thoracic kyphosis angle were significant variables influencing the lumbar kyphosis angle in both sexes. Spinal inclination correlated significantly with both the lumbar kyphosis angle and hip flexor strength in males, as well as with the lumbar kyphosis angle in females. -
Imajo Y.
Journal of Orthopaedic Science ( Journal of Orthopaedic Science ) 22 ( 1 ) 10 - 15 2017年01月
研究論文（学術雑誌）
Background: The Japanese Society for Spine Surgery and Related Research USSR) performed a third study on complications in spinal surgery in 2011. The purpose was to present information about surgery and complications in a large amount of elderly patients aged 65 years with lumbar spinal stenosis (LSS) without coexisting spondylolisthesis, spondylolysis, or scoliosis, and to compare patients aged >= 80 years to those aged 65-79 years.
Methods: A recordable optical disc for data storage was sent by JSSR in January 2012 to 1105 surgeons certified by the JSSR in order to collect surgical data. Data were returned by the end of May 2012.
Results: Data were accumulated for 8033 patients aged 65 years. The incidence of surgical complications was 10.8%, and did not differ significantly between age groups. The incidence of general complications was 2.7%, and differed significantly between age groups (p < 0.005). The highest incidence of surgical complications was for dural tear (DT) (3.6%), followed by deep wound infection (DWI) (1.4%), neurological complications (1.3%), and epidural hematoma (1.3%). Spinal instrumentation was applied in 30.3%. Incidences of surgical complications in instrumented and noninstrumented surgery were 17.3% and 8.8%. In instrumented surgery, incidences of surgical and general complications were higher in the >= 80 year age group than in the 65-79 year age group. Logistic regression analyses showed patients with microendoscopic surgery at increased risk of DT. Patients with diabetes mellitus and instrumented surgery showed increased risks of DWI.
Conclusions: Incidences of surgical complications did not differ significantly between age groups. Attention should be paid to both surgical and general complications, particularly for postoperative mental disease in instrumented surgery for patients >= 80 years old. (C) 2016 The Japanese Orthopaedic Association. Published by Elsevier B.V. All rights reserved. -
Effects of exercise and sports on bone health in pre- and postmenopausal women
Miyakoshi N.
Clinical calcium ( Clinical calcium ) 27 ( 1 ) 107 - 115 2017年01月
研究論文（学術雑誌）
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Kobayashi T.
Journal of Medical Case Reports ( Journal of Medical Case Reports ) 11 ( 1 ) 1 - 7 2017年01月
研究論文（学術雑誌）
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[Aging and homeostasis. Prevention and treatment of locomotive syndrome.]
Miyakoshi N
Clinical calcium 27 ( 7 ) 1013 - 1020 2017年
研究論文（学術雑誌）
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[Effects of exercise and sports on bone health in pre- and postmenopausal women.]
Miyakoshi N
Clinical calcium 27 ( 1 ) 107 - 115 2017年
研究論文（学術雑誌）
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A Case of Fracture-Redislocation of the Hip Caused by a Depressed Fracture of the Femoral Head Similar to a Hill-Sachs Lesion.
Okudera Y, Kijima H, Yamada S, Konishi N, Kubota H, Tazawa H, Tani T, Suzuki N, Kamo K, Sasaki K, Kawano T, Iwamoto Y, Miyakoshi N, Shimada Y
Case reports in orthopedics 2017 7409153 2017年
研究論文（学術雑誌）
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Okuyama K.
Spine Surgery and Related Research ( Spine Surgery and Related Research ) 1 ( 3 ) 129 - 134 2017年
研究論文（学術雑誌）
<p>Study Design: A prospective cohort study was conducted on patients with anterior cervical decompression and fusion (ACDF) with a polyetheretherketone cage (PEEKc).</p><p>Background: Advantages of a PEEKc have been proposed in the study. However, benefits of using a PEEKc in ACDF are still controversial.</p><p>Objective: To investigate the advantages of a PEEKc in ACDF.</p><p>Materials and Methods: A total of 27 patients was enrolled in the study. The mean age of patients was 55±10 years (mean±standard deviation). The mean duration of symptoms was 17±21 months. Surgery was conducted at C3/4 in 1, C4/5 in 3, C5/6 in 11, C6/7 in 9, C7/T1 in 2, and C5/6/7 in 1 patient. The mean follow-up period was 2.1±1.3 years. Clinical outcomes were analyzed by the Japanese Orthopedic Association Scores (JOA scores) and its recovery rate. Perioperative complications were also investigated. Radiologically, studies were conducted on interbody lordotic angle (IBLA), interbody height (IBH), and bone fusion rates.</p><p>Results: The JOA score was 14.7±1.4 preoperatively and 16.3±1.3 at the final follow-up. A significant improvement was observed (p<0.05). The mean recovery rate of JOA scores was 74.0±25.0%. The preoperative IBLA was 0.5±6.1°. The mean IBLA at the final follow-up was 1.9±5.6°. The preoperative IBH was 34.2±3.5 mm. The mean IBH at the final follow-up was 34.3±3.5 mm. No significant improvement in IBLA and IBH was observed. A complete union rate at 1 year and 2.3 years (range, 2.0-6.0) after surgery was 29% (8/28 segments) and 61% (11/18 segments). No major complications were observed.</p><p>Conclusions: Despite an unsatisfactory bone union rate and no significant improvement in IBLA and IBH at the final follow-up, ACDF with a PEEKc clinically provided a stable outcome with less surgical invasion and minor donor-site morbidity.</p>
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Cut-off value of medial meniscal extrusion for knee pain
Kijima H.
Advances in Orthopedics ( Advances in Orthopedics ) 2017 6793026 2017年
研究論文（学術雑誌）
Purpose. Medial meniscal extrusion (MME) has attracted attention as an index of knee pain in conjunction with clinical symptoms that could be more useful than the diagnosis of knee osteoarthritis on X-ray. However, the size of MME that would cause knee pain has not been clarified. The aim of the present study was to investigate the cut-off value of MME for knee pain. Methods. A total of 318 knees were evaluated. The presence of current or past knee pain was confirmed by interview. Next, MME was measured using vertical sonographic images of the medial joint spaces during weightbearing. Results. Overall, 71 knees were painful (P-group), and 247 knees were not (N-group). MME was 5.9 ± 1.8 mm in the P-group and 2.9 ± 1.5 mm in the N-group (P<
0.0001). Analysis of the receiver operating characteristic curve showed that the cut-off value of MME for knee pain was 4.3 mm, with sensitivity of 0.8451 and specificity of 0.8502. In addition, 64% of knees without pain cases at the time of examination whose MME exceeded this cut-off value had past knee pain. Conclusions. The sensitivity and specificity of MME for knee pain were very high with a cut-off value of 4.3 mm. -
Erratum：高度の内側型変形性膝関節症に対してDouble level osteotomy（DFO＋TCVO）を施行した1例 ［東北膝関節研究会会誌 25巻 (2016) p. 39-43］
斉藤 公男, 佐々木 香奈, 嘉川 貴之, 瀬川 豊人, 藤井 昌, 佐藤 千恵, 大内 賢太郎, 杉村 祐介, 赤川 学, 塚本 泰朗, 畠山 和利, 蝦名 寿仁, 青沼 宏, 齊藤 英知, 島田 洋一, 宮腰 尚久, 木島 泰明, 今野 則和, 冨手 貴教
東北膝関節研究会会誌 ( 東北膝関節研究会 ) 26 ( 0 ) 64 - 67 2017年
研究論文（学術雑誌）
<p>J-STAGE登載準備過程において発見された軽微ではない誤植について下記の通り訂正いたします。東北膝関節研究会 事務局</p><p>訂正箇所：39頁 共著者名 今野<u>和則</u> → 今野<u>則和</u> 畠山和<u>則</u> → 畠山和<u>利</u></p>
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Unoki E.
Spine Surgery and Related Research ( Spine Surgery and Related Research ) 1 ( 2 ) 90 - 95 2017年
研究論文（学術雑誌）
<p>Introduction: Sacroiliac joint pain (SIJP) after lumbar fusion surgery has recently gained attention as a source of low back pain after lumbar fusion. There are two risk factors for postoperative SIJP, i.e., fusion involving the sacrum and multiple-segment fusion. In this study, we examined whether SIJP could occur more frequently in patients with two risk factors (multiple-segment fusion to sacrum). Further, we examined SIJP after multiple-segment (≥3) lumbar fusion, focusing on the difference between floating fusion (non-fused sacrum) and fixed fusion (fused sacrum).</p><p>Methods: Ninety-one patients who underwent multiple-segment lumbar fusion were included. Patients without preoperative clinical SIJP were considered. Of these, 17 developed new-onset SIJP. We investigated postoperative SIJP development, duration from surgery to SIJP onset, and postoperative treatment outcomes of SIJP patients using Japanese Orthopaedic Association (JOA) scores. We compared the findings between floating fusion group and fixed fusion group.</p><p>Results: The incidence of SIJP was significantly higher with fixed fusion (32.1%) than with floating fusion (12.7%). The mean time of onset of sacroiliac joint pain was at 8.63 (2-13) months after surgery in the floating fusion group and 3.78 (1-10) months after surgery in the fixed fusion group, indicating that incidence occurred significantly earlier in the fixed fusion group. Our treatment outcome indicated that the mean JOA score significantly improved in the floating fusion group from 5.13 at the time of onset to 9.50 at the time of final follow-up; however, in the fixed fusion group, it improved from 5.78 at the time of onset to 7.33 at the time of final follow-up, indicating no significant improvement.</p><p>Conclusions: In multiple-segment lumbar fusion, fixed fusion (fused sacrum) has a very high risk of SIJP. In addition, the onset of SIJP in such cases may occur earlier. This aspect deserves consideration, given the difficulty of pain treatment.</p>
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Imajo Y.
Spine Surgery and Related Research ( Spine Surgery and Related Research ) 1 ( 1 ) 7 - 13 2017年
研究論文（学術雑誌）
<p>Introduction: Details of surgical and general complications for patients with cervical spondylotic myelopathy (CSM) are still uncertain. The purpose of this study was to describe surgeries and their complications among Japanese patients with CSM. Methods: The Japanese Society for Spine Surgery and Related Research performed a nationwide survey on spine surgery and complications in 2011. Data of patients with 2,961 CSM >40 years old were included. The clinicopathological variables were basic demographic and clinical information, surgical information, and surgical and general complications. To examine the influence of age, variables were compared among three age groups: patients 40-64 (n=1,123), 65-74 (n=966), and ≥75 (n=872) years of age. Results: The study included 1,970 males and 991 females and the mean age was 64.3 years old. There were 168 anterior (5.7%) and 2,770 posterior (94.2%) approach surgeries. The vast majority of patients with CSM were treated using the posterior approach, 89.4% of whom had decompression surgery only. Anterior surgeries were more common in the younger age group, but posterior surgeries were equally distributed. The incidence of total complications including surgical/general complications was similar for the anterior (16/168; 9.5%) and posterior (295/2,770; 10.6%) approaches. No patient died on the operating table, but four patients (0.1%) died within one month after surgery. No association was detected between complications and age, comorbidity, and other surgical factors. The incidence of complications was similar for the different age groups. However general complications were predominantly observed in the older group and those who had instrumented surgery. Conclusions: The results indicate that the indication and surgical performance for patients with CSM is favorable in Japan, despite the super-aging population. Few serious complications were reported in this study. However, more detailed informed consent about surgical and, in particular, general complications is necessary for the older patients with CSM.</p>
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ジャンプ動作における動的下肢アライメントと体幹バランスの関連性
斉藤 公男, 嘉川 貴之, 那波 康隆, 瀬川 豊人, 藤井 昌, 佐藤 千恵, 大内 賢太郎, 杉村 祐介, 赤川 学, 塚本 泰朗, 松永 俊樹, 齊藤 英知, 島田 洋一, 宮腰 尚久, 今野 則和, 木島 泰明, 冨手 貴教, 佐々木 香奈
東北膝関節研究会会誌 ( 東北膝関節研究会 ) 26 ( 0 ) 39 - 43 2017年
研究論文（学術雑誌）
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斉藤 公男, 高橋 靖博, 千田 聡明, 畠山 和利, 渡邉 基起, 石川 順基, 髙橋 裕介, 鈴木 真理, 村田 脩, 島田 洋一, 宮腰 尚久, 松永 俊樹, 巌見 武裕, 本郷 道生, 粕川 雄司, 齊藤 英知, 益谷 法光
リハビリテーション医学 ( 公益社団法人 日本リハビリテーション医学会 ) 54 ( 1 ) 31 - 35 2017年
研究論文（学術雑誌）
<p>安全にバランス機能を測定するため，動的座位によるバランス計測装置を開発した．本装置は、座面反力（重心動揺）を検出する計測装置と，モータの回転により座面を側方傾斜させ一定の周期で座面を振動させる外乱刺激装置で構成される．3軸力学センサを用い，座面の圧力と圧力中心点を算出することが可能である．座位で計測を行うことで安全であり，下肢の影響を受けないため体幹バランス能力の評価にも使用できると考えている．現在までに行った基礎実験やフィールドワークでの活動，および本装置を用いた介入試験の結果と有用性，今後の活動について概説する．</p>
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Systemic administration of insulin-like growth factor(IGF)-binding protein-4(IGFBP-4)increases bone formation parameters in mice by increasing IGF bioavailability via an IGFBP-4 protease-dependent mechanism.
Miyakoshi N, et al.
Endocrinology 142 ( 6 ) 2641 - 2648 2001年01月 [査読有り]
研究論文（学術雑誌）
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Evaluation of long-term sequential changes in bone mass and strength following withdrawal of incadronate disodium(YM175)in ovariectomized rats.
Miyakoshi N, et al.
J Orthop Sci 6 ( 2 ) 167 - 176 2001年01月 [査読有り]
研究論文（学術雑誌）
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Evidence that IGF-binding protein-5 functions as a growth factor.
Miyakoshi N, et al.
J Clin Invest 107 ( 1 ) 73 - 81 2001年01月 [査読有り]
研究論文（学術雑誌）
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Outcome of one-level posterior lumber interbody fusion for spondylolisthesis and postoperative intervertebral disc degeneration adjacent to the fusion.
Miyakoshi N, et al.
Spine 25 ( 14 ) 1837 - 1842 2000年01月 [査読有り]
研究論文（学術雑誌）
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Anterior decompression with single segmental spinal interbody fusion for lumbar burst fracture.
Miyakoshi N, et al.
Spine 24 ( 1 ) 67 - 73 1999年01月 [査読有り]
研究論文（学術雑誌）
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Histomorphometric evaluation of the effects of ovariectomy on bone turnover in rat caudal vertebrae.
Miyakoshi N, et al.
Calcif Tissue Int 64 318 - 324 1999年01月 [査読有り]
研究論文（学術雑誌）
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Effects of recombinant insulin-like growth factor-binding protein-4 on bone formation parameters in mice.
Miyakoshi N, et al.
Endocrinology 140 ( 12 ) 5719 - 5728 1999年01月 [査読有り]
研究論文（学術雑誌）
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Bone-loss pattern of corticosteroid-induced osteopenia in rats : A node-strut analysis of the tibia.
Miyakoshi N, et al.
J Bone Miner Metab 15 94 - 99 1997年01月 [査読有り]
研究論文（学術雑誌）
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Preventive effects of intermittent administration of human parathyroid hormone on steroid-induced osteopenia in rats.
Miyakoshi N
J Orthop Sci 1 318 - 328 1996年01月 [査読有り]
研究論文（学術雑誌）