Graduate School of Medicine  Doctorial Course in Medicine  Oncoregulatory Medicine  Department of Comprehensive Cancer Control

Research Fields, Keywords

Esophageal surgery, Surgical oncology, Personalized treatment for cancer, Genetic polymorphism

Graduating School 【 display / non-display


    Akita University   Faculty of Medicine   Graduated

Campus Career 【 display / non-display

  • 2017.04

    Akita University   Graduate School of Medicine   Doctorial Course in Medicine   Oncoregulatory Medicine   Professor  

Research Field (grants-in-aid-for-scientific-research classification) 【 display / non-display

  • Digestive surgery

  • General surgery

Qualification acquired 【 display / non-display

  • Doctor


Published Papers 【 display / non-display

  • Laparoscopic Transhiatal Surgery for Multiple Epiphrenic Esophageal Diverticula

    Sasaki Tomohiko, Motoyama Satoru, Yasui Ouki, Kato Yujiro, Takahashi Teiji

    The Japanese Journal of Gastroenterological Surgery ( The Japanese Society of Gastroenterological Surgery )  51 ( 9 ) 543 - 550   2018

    <p>A 53-year-old man was referred for detailed examinations on dysphagia. A gastrographin contrast medium study and an esophagoscopy revealed both a 6 cm right epiphrenic diverticulum and a 3 cm left epiphrenic diverticulum in the esophagus. Manometry examination showed a synchronous abnormal contraction and absence of a primary peristaltic wave. Furthermore, lower esophageal sphincter (LES) pressure was high. We diagnosed multiple epiphrenic esophageal diverticula with an esophageal motility disorder. We performed laparoscopic transhiatal diverticulectomy and Dor's fundoplication following Heller myotomy. The postoperative course was uneventful, and his symptoms improved. Simultaneous bilateral epiphrenic esophageal diverticula are rare diseases. Laparoscopic transhiatal surgery can be a useful treatment for this disease.</p>

    DOI CiNii

  • A Surgically Treated Case of Delayed Refractory Chyloperitoneum Developed after Gastrectomy against Advanced Gastric Cancer

    FUJITA Hiromu, MOTOYAMA Satoru, SASAKI Tomohiko, SATO Yusuke, KAWAKITA Yuta, NAKAMURA Masakatsu

    Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) ( Japan Surgical Association )  79 ( 12 ) 2408 - 2412   2018

    A 74-year-old man underwent distal gastrectomy, D1 + with No.14v lymph node dissection, and Roux-en Y reconstruction for advanced gastric cancer with infiltration into the transverse mesocolon. When about 2 weeks had elapsed after initiation of adjuvant chemotherapy, he developed abdominal distention. Ascites was confirmed by a CT scan undertaken 3 months after the surgery. Abdominal paracentesis yielded a milky white ascites with remarkably elevated triglyceride level. Chylous ascites was thus diagnosed. Since conservative therapy was unsuccessful, he was referred to our hospital for further treatments 7 months after the surgery. Plain abdominal CT scan performed immediately after lymphangiography revealed leakage of lipiodol around the celiac artery and/or common hepatic artery. Upon laparotomy, we ligated and sutured the chylorrhea site to close the chylorrhea by using an absorbable tissue-reinforcing material and a physiological tissue adhesive.<BR>Prolonged chylorrhea for a long time extremely worsens the general condition of the patient. When we encounter refractory chylous ascites, it is important to perform surgical therapy without hesitation that can lead to a curative therapy.

    DOI CiNii

  • Prevention of Evaporation Caused by a Rapid Immunohistochemistry Method Applying Non-contact Alternating-Current Electric-Field Mixing

    HOSHINO Iku, SATO Yusuke, MOTOYAMA Satoru, NANJO Hiroshi, AKAGAMI Yoichi, MINAMIYA Yoshihiro, IMAI Kazuhiro, NAKAMURA Ryuta, SAITO Yoshitaro, FUJISHIMA Satoshi, KURIHARA Nobuyasu, Wakamatsu Yuki, SAITO Hajime, TERATA Kaori

    Journal of the Japan Society for Precision Engineering ( The Japan Society for Precision Engineering )  84 ( 4 ) 383 - 387   2018

    <p>It is widely recognized that pathology is the most important factor for staging and selecting effective chemotherapy for patients with cancer. Immunohistochemistry (IHC) is a reliable screening method, but intra-operative diagnosis by frozen section with IHC is not possible because IHC takes approximately 6 hours. We recently developed a rapid-IHC method that makes use of an alternating current (AC) electric field to facilitate the antigen-antibody reaction, and reported its usefulness for detection of lung cancer and breast cancer. The antibody is mixed within microdroplets as the voltage is switched on and off at specific intervals. The resultant Coulomb force stirs the diluted solution on the sections, which increases the opportunity for contact. The rapid-IHC device reduces the time required for IHC as well as the amount of antibody required for analyses. The device may also be applied for in situ hybridization (ISH); however, ISH requires a warm temperature, such as 37℃, and a longer processing time than the rapid-IHC method. Consequently, evaporation can be a problem during ISH. The aim of the present study was to evaluate the utility and reliability of an oil cover and cover cap made of polyethylene terephthalate (PET) for preventing evaporation due to the AC electric field applied to facilitate the antigen-antibody reaction. We have shown that both the oil cover and PET cover cap prevented evaporation when using the rapid-IHC device.</p>

    DOI CiNii

  • New PET/CT criterion for nodal staging in non-small cell lung cancer: measurement of the ratio of section area of standard uptake values ≥2.5/lymph node section area

    Yoshitaro Saito, Kazuhiro Imai, Koichi Ishiyama, Hajime Saito, Satoru Motoyama, Yusuke Sato, Hayato Konno, Satoshi Fujishima, Manabu Hashimoto, Yoshihiro Minamiya

    General Thoracic and Cardiovascular Surgery   65 ( 6 ) 350 - 357   2017.06

    DOI PubMed

  • Phase II study of personalized peptide vaccination for previously treated advanced colorectal cancer

    Kibe S, Yutani S, Motoyama S, Nomura T, Tanaka N, Kawahara A, Yamaguchi T, Matsueda S, Komatsu N, Miura M, Hinai Y, Hattori S, Yamada A, Kage M, Itoh K, Akagi Y, Sasada T

    Cancer Immunol Res     2014.01  [Refereed]

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