研究者詳細 - 本郷　道生

OYA KEITA, TSUCHIE HIROYUKI, NAGASAWA HIROYUKI, HONGO MICHIO, KASUKAWA YUJI, KUDO DAISUKE, SHOJI RYO, KASAMA FUMIHITO, KAWARAGI TAKASHI, WATANABE MANABU, TOMINAGA KENTA, MIYAKOSHI NAOHISA

In Vivo ( Production services Kyorinsha Co., Ltd. ) 38 ( 3 ) 1074 - 1078 2024年

CiNii Research

The Impact of Reduced Skeletal Muscle Mass on Patients with Knee Osteoarthritis

Akagawa M.

Acta Medica Okayama ( Acta Medica Okayama ) 78 ( 3 ) 245 - 250 2024年

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Comparative efficacy of ultrasound guidance and fluoroscopy or computed tomography guidance in spinal nerve injections: a systematic review and meta-analysis

Kimura R.

European Spine Journal ( European Spine Journal ) 32 ( 12 ) 4101 - 4110 2023年12月

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Preoperative factors affecting the two-year postoperative patient-reported outcome in single-level lumbar grade I degenerative spondylolisthesis

Kanchiku T.

North American Spine Society Journal ( North American Spine Society Journal ) 16 2023年12月

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Risser sign grade 4の思春期特発性側弯症におけるCobb角進行と危険因子の検討

若林玲奈, 本郷道生, 三澤晶子, 木村竜太, 工藤大輔, 島田洋一, 宮腰尚久

Journal of Spine Research ( 一般社団法人日本脊椎脊髄病学会 ) 14 ( 11 ) 1377 - 1382 2023年11月

はじめに：思春期特発性側弯に対する装具治療は，一般に骨成熟が終盤と評価されるRisser sign grade 4以上には積極的推奨はされていない．しかし，Risser sign grade 4でもCobb角が進行する症例をしばしば経験する．対象と方法：対象は2016年から2020年に当院を初診し，Risser sign grade 4を呈する思春期特発性側弯症のうち1年以上経過観察した42例であった．Cobb角の変化，患者背景，身体所見，放射線学的評価を，進行群と非進行群に分け比較検討した．結果：進行群8例，非進行群34例で，進行群ではCobb角が初診時28.7°が経過観察時35.8°となり，平均7.1°増加した．初潮から初診までの経過期間は非進行群24.2ヶ月に対し進行群9.7ヶ月と有意に短く（P=0.003），身長変化は非進行群が1.8 cm増加したのに対し，進行群が2.9 cm増加と有意に大きかった（P=0.02）．その他では差を認めなかった．結語：Risser sign grade 4の思春期特発性側弯症の約2割で側弯の進行を認めた．進行群では，初潮から初診までの経過期間が短く，身長の伸びが大きかった．初潮から初診までの経過期間と身長変化により，進行が危惧される場合は装具治療も考慮する必要がある．

DOI CiNii Research

秋田県における側弯症検診の現状と課題

三澤晶子, 本郷道生, 工藤大輔, 若林玲奈, 木村竜太, 島田洋一, 宮腰尚久

Journal of Spine Research ( 一般社団法人日本脊椎脊髄病学会 ) 14 ( 11 ) 1366 - 1371 2023年11月

はじめに：本県では1984年からモアレ法による学校検診を行っており，運動器検診開始後も継続している．今回，秋田市教育委員会のデータ提供により，運動器検診の結果とモアレ法による側弯症検診の結果を比較した．対象と方法：2017～2020年度に運動器検診で脊柱に所見ありとされ二次検診を受診した1,442例と，モアレ検診で所見ありとして二次検診を受診した474例を対象とし，X線撮影によるCobb角10°以上の陽性率を算出した．結果：陽性適中率は運動器検診で39%，モアレ検診では60%であった．中学生の陽性適中率に限ると，運動器検診で57%とモアレ検診と同程度だったが，診断された13%が運動器検診で新規に陽性，87%が継続して陽性であり，大多数の症例がモアレ検診で側弯症の診断を受けていた．結語：本研究の結果から，改めて運動器検診との対比においてモアレ検診の有用性が明らかになった．検診を進めるにあたり，検診後のフォローアップ体制の充実も必要と考えられた．また，検診結果のフィードバックのため，個人情報保護の問題等解決に向け，検診の発展には教育委員会や医師会への働きかけと連携が必要である．

DOI CiNii Research

Effects of Soft Tissue Sarcoma and Doxorubicin on Bone Metabolism in Mice

Kasama F.

In Vivo ( In Vivo ) 37 ( 4 ) 1532 - 1539 2023年07月

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A Comparison of Hidden Blood Loss Between Multilevel Posterior Lumbar Interbody Fusion and Lateral Lumbar Interbody Fusion in Adult Spinal Deformity Patients

Kinoshita H.

Global Spine Journal ( Global Spine Journal ) 2023年

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Neurological Analysis Based on the Terminal End of the Spinal Cord and the Narrowest Level of Injured Spine in Thoracolumbar Spinal Injuries

Hatakeyama Y.

Acta Medica Okayama ( Acta Medica Okayama ) 77 ( 5 ) 499 - 509 2023年

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Two Cases of Degenerative Cervical Spondylotic Myelopathy in Adults with Athetoid and Dystonic Cerebral Palsy

Kinoshita H.

American Journal of Case Reports ( American Journal of Case Reports ) 24 2023年

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Effect of low body mass index on clinical recovery after fusion surgery for osteoporotic vertebral fracture A retrospective, multicenter study of 237 cases

Inoue G.

Medicine (United States) ( Medicine (United States) ) 101 ( 52 ) 2022年12月

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Relationship between Intervertebral Disc Compression Force and Sagittal Spinopelvic Lower Limb Alignment in Elderly Women in Standing Position with Patient-Specific Whole Body Musculoskeletal Model

Miura T.

International Journal of Environmental Research and Public Health ( International Journal of Environmental Research and Public Health ) 19 ( 24 ) 2022年12月

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Intravascular Administration of Acridine Orange and Zoledronate in a Bone Metastasis Model of Breast Cancer

Shoji R.

Anticancer Research ( Anticancer Research ) 42 ( 11 ) 5357 - 5363 2022年11月

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A prospective analysis of concentration of 25-OHD between northern and southern district in Japan in year-round study

Horikawa A.

Medicine (United States) ( Medicine (United States) ) 101 ( 43 ) 2022年10月

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Degenerative Lumbar Spondylolisthesis Patients With Movement-related Low Back Pain Have Less Postoperative Satisfaction After Decompression Alone

Hirota R.

Spine ( Spine ) 47 ( 19 ) 1391 - 1398 2022年10月

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特集医工連携と腰痛新たな筋骨格モデルを用いた脊柱後弯患者における股関節間力,椎間板負荷の解析

三浦隆徳, 粕川雄司, 本郷道生, 宮腰尚久

脊椎脊髄ジャーナル ( 三輪書店 ) 35 ( 5 ) 303 - 308 2022年09月

DOI CiNii Research

Earlier appearance of Risser sign on ultrasound versus radiograph in adolescent idiopathic scoliosis

Hongo M.

Journal of Clinical Imaging Science ( Journal of Clinical Imaging Science ) 12 2022年07月

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The relationship between chronic kidney disease and denosumab-induced hypocalcemia in high-age osteoporotic patients

Horikawa A.

Journal of Bone and Mineral Metabolism ( Journal of Bone and Mineral Metabolism ) 40 ( 4 ) 670 - 676 2022年07月

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整形トピックス三次元筋骨格モデルを用いた成人脊柱変形解析

飯田純平, 島田洋一, 本郷道生, 宮腰尚久

整形外科 ( 南江堂 ) 73 ( 5 ) 438 - 438 2022年05月

DOI CiNii Research

Development of New Mouse Breast Cancer Model of Local Bone Metastasis and Verification Using Bisphosphonates

Shoji R.

In Vivo ( In Vivo ) 36 ( 2 ) 667 - 671 2022年03月

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特集成人脊柱変形Up to Date 第4章　治療成人脊柱変形に対する保存療法-脊柱変形,疼痛への効果

本郷道生, 宮腰尚久, 粕川雄司

脊椎脊髄ジャーナル ( 三輪書店 ) 34 ( 11 ) 736 - 742 2022年03月

DOI CiNii Research

Chronic atlantoaxial rotatory fixation with neurofibromatosis type I: A case report

Ono Y.

Surgical Neurology International ( Surgical Neurology International ) 13 2022年

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Impact of a specialized outpatient clinic on bone metastasis and its burden on spine surgeons

Tsuchie H.

In Vivo ( In Vivo ) 35 ( 6 ) 3575 - 3579 2021年12月

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Risk factor for poor patient satisfaction after lumbar spine surgery in elderly patients aged over 80 years

Hikata T.

Clinical Spine Surgery ( Clinical Spine Surgery ) 34 ( 4 ) E223 - E228 2021年05月

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Pediatric spinal infection with epidural abscess: A report of two cases

Shoji R.

Surgical Neurology International ( Surgical Neurology International ) 12 2021年04月

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特集運動器のバイオメカニクス-Cutting Edge 2021:新しい解析手法と知見 Ⅰ.脊椎のバイオメカニクスと下肢アライメント三次元筋骨格モデルを用いた脊柱変形解析

本郷道生, 宮腰尚久, 島田洋一

整形・災害外科 ( 金原出版 ) 64 ( 5 ) 507 - 514 2021年04月

DOI CiNii Research

Thin Cervical Spinal Cord Between Ossifications of the Ligamentum Flavum and the Posterior Longitudinal Ligament: Case Report and Literature Review

Ishikawa Y.

World Neurosurgery ( World Neurosurgery ) 145 83 - 88 2021年01月

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Herniation of the cauda equina into the facet joint through a pseudomeningocele: A case report and literature review

Iida J.

Surgical Neurology International ( Surgical Neurology International ) 12 2021年

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The Effects of Trends in Osteoporosis Treatment on the Incidence of Fractures

Horikawa A.

Journal of Osteoporosis ( Journal of Osteoporosis ) 2021 2021年

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Spinal cord compression with occult bony fragment in osteoporotic vertebral fracture: A case report

Ishikawa Y.

Spine Surgery and Related Research ( Spine Surgery and Related Research ) 5 ( 4 ) 310 - 312 2021年

DOI CiNii Research

Growing Rod Surgery for Early-Onset Scoliosis in an Osteogenesis Imperfecta Patient

Ono Y.

World Neurosurgery ( World Neurosurgery ) 144 178 - 183 2020年12月

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Pyogenic Atlantoaxial Rotational Dislocation Representing Adult Torticollis with Vertebral Artery Occlusion: A Case Report and Review

Ishikawa Y.

World Neurosurgery ( World Neurosurgery ) 144 82 - 87 2020年12月

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Surgical treatment of complete fifth lumbar osteoporotic vertebral burst fracture: A retrospective case report of three patients

Abe K.

Surgical Neurology International ( Surgical Neurology International ) 11 2020年12月

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Inhibition of Autograft Bone Resorption by Antibone Resorptive Agents After Spinal Reconstruction Surgery for Extensive Cervical Chondrosarcoma: A Case Report with a 10-Year Follow-Up

Miyakoshi N.

World Neurosurgery ( World Neurosurgery ) 142 239 - 245 2020年10月

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特集病態に応じた腰痛のリハビリテーション診療高齢者の脊柱変形に伴う腰痛

島田洋一, 本郷道生, 宮腰尚久

総合リハビリテーション ( 株式会社医学書院 ) 48 ( 9 ) 827 - 834 2020年09月

DOI CiNii Research

Short- versus long-segment posterior spinal fusion with vertebroplasty for osteoporotic vertebral collapse with neurological impairment in thoracolumbar spine: A multicenter study

Ishikawa Y.

BMC Musculoskeletal Disorders ( BMC Musculoskeletal Disorders ) 21 ( 1 ) 2020年08月

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Effect of bisphosphonates or teriparatide on mechanical complications after posterior instrumented fusion for osteoporotic vertebral fracture: A multi-center retrospective study

Kawabata A.

BMC Musculoskeletal Disorders ( BMC Musculoskeletal Disorders ) 21 ( 1 ) 2020年07月

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Murata K.

European Spine Journal ( European Spine Journal ) 29 ( 7 ) 1597 - 1605 2020年07月

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Effectiveness of circular external fixator in periprosthetic fractures around the knee

Nozaka K.

BMC Musculoskeletal Disorders ( BMC Musculoskeletal Disorders ) 21 ( 1 ) 2020年05月

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Recurrent dysphagia after lower posterior cervical fusion

Ishikawa Y.

Surgical Neurology International ( Surgical Neurology International ) 11 ( 114 ) 2020年05月

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Effects of bazedoxifene and low-intensity aerobic exercise on bone and fat parameters in ovariectomized rats

Yuasa Y.

Journal of Bone and Mineral Metabolism ( Journal of Bone and Mineral Metabolism ) 38 ( 2 ) 179 - 187 2020年03月

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本郷道生, 宮腰尚久, 島田洋一

整形・災害外科 ( 金原出版 ) 63 ( 2 ) 157 - 163 2020年02月

DOI CiNii Research

The surgical outcomes of spinal fusion for osteoporotic vertebral fractures in the lower lumbar spine with a neurological deficit

Isogai N.

Spine Surgery and Related Research ( Spine Surgery and Related Research ) 4 ( 3 ) 199 - 207 2020年01月

Introduction: Osteoporotic vertebral fracture (OVF) is the most common osteoporotic fracture, and some patients require surgical intervention to improve their impaired activities of daily living with neurological deficits. However, many previous reports have focused on OVF around the thoracolumbar junction, and the surgical outcomes of lumbar OVF have not been thoroughly discussed. We aimed to investigate the surgical outcomes for lumbar OVF with a neurological deficit.Methods: Patients who underwent fusion surgery for thoracolumbar OVF with a neurological deficit were enrolled at 28 institutions. Clinical information, comorbidities, perioperative complications, Japanese Orthopaedic Association scores, visual analog scale scores, and radiographic parameters were compared between patients with lower lumbar fracture (L3-5) and those with thoracolumbar junction fracture (T10-L2). Each patient with lower lumbar fracture (L group) was matched with to patients with thoracolumbar junction fracture (T group).Results: A total 403 patients (89 males and 314 females, mean age: 73.8 ± 7.8 years, mean follow-up: 3.9 ± 1.7 years) were included in this study. Lower lumbar OVF was frequently found in patients with lower bone mineral density. After matching, mechanical failure was more frequent in the L group (L group: 64%, T group: 39%; p < 0.001). There was no difference between groups in the clinical and radiographical outcomes, although the rates of complication and revision surgery were still high in both groups.Conclusions: The surgical intervention for OVF is effective in patients with myelopathy or radiculopathy regardless of the surgical level, although further study is required to improve clinical and radiographical outcomes.Level of evidence: Level III

DOI CiNii Research

Treatment of spontaneous osteonecrosis of the knee by daily teriparatide: A report of 3 cases

Horikawa A.

Medicine ( Medicine ) 99 ( 5 ) 2020年01月

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Reply to the editor: Surgical treatment of osteoporotic vertebral fracture with neurological deficit-a nationwide multicenter study in japan

Hosogane N.

Spine Surgery and Related Research ( Spine Surgery and Related Research ) 4 ( 3 ) 292 - 293 2020年01月

DOI CiNii Research

Cervical meningioma resection including the inner dura through an open-door laminoplasty using hydroxyapatite spacers: A case report

Miyakoshi N.

Surgical Neurology International ( Surgical Neurology International ) 11 2020年

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Impact of sagittal spine-pelvis-leg alignment and muscle strength on quality of life and low back pain in rural Japanese community- dwelling middle-aged and elderly persons

Kudo D.

Journal of Back and Musculoskeletal Rehabilitation ( Journal of Back and Musculoskeletal Rehabilitation ) 33 ( 2 ) 263 - 268 2020年

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Locomotive Syndrome Is Associated with Health-Related Quality of Life and Low Back Pain in the Elderly, Including Individuals More Than 80 Years Old

Kasukawa Yuji, Miyakoshi Naohisa, Hongo Michio, Ishikawa Yoshinori, Kudo Daisuke, Kimura Ryota, Ono Yuichi, Shimada Yoichi

Progress in Rehabilitation Medicine ( 公益社団法人日本リハビリテーション医学会 ) 5 ( 0 ) n/a 2020年

Objectives: The extent to which locomotive syndrome is associated with low back pain (LBP), health-related quality of life (HRQOL), and impairment of activities of daily living among elderly men and women remains poorly documented. This study evaluated associations between locomotive syndrome and both HRQOL and LBP as assessed using a questionnaire completed by elderly individuals, including some >80 years old.Methods: We conducted a survey assessing locomotive syndrome using the loco-check, HRQOL using the Short-Form 36 questionnaire (SF-36), and LBP using the Roland-Morris Disability Questionnaire (RDQ) among individuals >60 years old. SF-36 and RDQ scores were compared between 253 subjects with and without locomotive syndrome.Results: Fifty-seven men (48%) and 71 women (53%) were diagnosed with locomotive syndrome. Subjects of both sexes with locomotive syndrome scored significantly lower for eight items from SF-36. Physical and mental component summary scores were significantly worse in women with locomotive syndrome in their 60s and 70s. RDQ scores were significantly higher in participants with locomotive syndrome for men in their 60s and for both men and women in their 70s.Conclusions: Locomotive syndrome was associated with impaired HRQOL and worse LBP among men and women >60 years old. Differences in HRQOL and LBP between subjects with and without locomotive syndrome were significant for both men and women in their 60s and 70s, but not in their 80s. Locomotive syndrome should be prevented to maintain HRQOL, particularly for men and women in their 60s and 70s.

DOI CiNii Research

高齢者の脊椎疾患に対するスポーツと運動療法

本郷道生, 宮腰尚久, 島田洋一

日本整形外科スポーツ医学会雑誌 ( 一般社団法人日本整形外科スポーツ医学会 ) 40 ( 2 ) 135 - 140 2020年

高齢者において，骨粗鬆症性椎体骨折後の変形や，椎間板，靱帯の変性，筋力低下による脊柱変形や，腰部脊柱管狭窄症が生じ，慢性の腰背部痛，下肢痛，身体機能低下を生じて，生活の質（QOL）は低下する．これらの脊椎変性疾患に対してさまざまな保存療法が行なわれるが，運動療法も有効とされる．運動療法やスポーツ活動を行なって，体幹の筋力や可動性，体力を改善させることにより，低下した身体機能や，QOL，姿勢そして腰背部痛の改善に有効であることが示されている．

DOI CiNii Research

Rapidly Progressing Symptomatic Calcification of Ligamentum Flavum in Thoracic Spine After Osteoporotic Vertebral Fractures

Miyakoshi N.

World Neurosurgery ( World Neurosurgery ) 132 63 - 66 2019年12月

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Complications after spinal fixation surgery for osteoporotic vertebral collapse with neurological deficits: Japan Association of Spine Surgeons with ambition multicenter study

Sakai Y.

Journal of Orthopaedic Science ( Journal of Orthopaedic Science ) 24 ( 6 ) 985 - 990 2019年11月

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Intraoperative Visible Air Bubbling Recorded as a Sign of Massive Venous Air Embolism During Prone Position Surgery for Extensive Ossification of Spinal Ligaments: A Case Report with a Video Clip

Miyakoshi N.

World Neurosurgery ( World Neurosurgery ) 131 38 - 42 2019年11月

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Surgical outcomes of spinal fusion for osteoporotic vertebral fracture in the thoracolumbar spine: Comprehensive evaluations of 5 typical surgical fusion techniques

Watanabe K.

Journal of Orthopaedic Science ( Journal of Orthopaedic Science ) 24 ( 6 ) 1020 - 1026 2019年11月

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Comparison of Posterior Lumbar Interbody Fusion and Microendoscopic Muscle-preserving Interlaminar Decompression for Degenerative Lumbar Spondylolisthesis With >5-Year Follow-up

Kimura R.

Clinical Spine Surgery ( Clinical Spine Surgery ) 32 ( 8 ) E380 - E385 2019年10月

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連載 X線診断Q & A X線診断Q&A

本郷道生

整形外科 ( 南江堂 ) 70 ( 10 ) 1083 - 1084 2019年09月

DOI CiNii Research

An epidemiological study of traumatic spinal cord injuries in the fastest aging area in Japan

Kudo D.

Spinal Cord ( Spinal Cord ) 57 ( 6 ) 509 - 515 2019年06月

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特集傍脊柱筋の機能解剖学,姿勢制御と手術アプローチ第1章　解剖と機能胸椎前方・側方の筋肉の解剖と機能

本郷道生, 島田洋一, 宮腰尚久

脊椎脊髄ジャーナル ( 三輪書店 ) 32 ( 4 ) 279 - 283 2019年04月

DOI CiNii Research

特集脊椎脊髄外科の最近の進歩 Ⅰ.脊椎アライメント/画像診断脊柱骨盤アライメントとQOL

本郷道生, 宮腰尚久, 島田洋一

整形・災害外科 ( 金原出版 ) 62 ( 5 ) 437 - 442 2019年04月

DOI CiNii Research

Surgical outcomes of spinal fusion for osteoporotic thoracolumbar vertebral fractures in patients with Parkinson's disease: What is the impact of Parkinson's disease on surgical outcome?

Watanabe K.

BMC Musculoskeletal Disorders ( BMC Musculoskeletal Disorders ) 20 ( 1 ) 2019年03月

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A prospective comparative study of intravenous alendronate and ibandronate for the treatment of osteoporosis

Horikawa A.

Medicine (United States) ( Medicine (United States) ) 98 ( 6 ) 2019年02月

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Comparison of Health-related Quality of Life between Double-door Laminoplasty and Selective Laminoplasty for Degenerative Cervical Myelopathy, with a Minimum Follow-up of 5 Years

Hirota R.

Spine ( Spine ) 44 ( 4 ) E211 - E218 2019年02月

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Impact of spinal kyphosis on gastric myoelectrical activity in elderly patients with osteoporosis

Tsuchie H.

Biomedical Research (Japan) ( Biomedical Research (Japan) ) 40 ( 6 ) 215 - 223 2019年

An association between spinal kyphosis and gastroesophageal reflux disease (GERD) was reported in recent years. However, it remains unclear whether spinal kyphosis affects gastric motility. We evaluated the changes in myoelectrical activity measured by electrogastrography (EGG) in elderly osteoporosis patients. A total of 18 patients scheduled for the treatment of osteoporosis were included in this study. They were analyzed by recording EGG to assess myoelectrical activity and heart rate variability (HRV) to evaluate the autonomic nervous system function before and after meals. Dominant power (DP) representing the strength of gastric electrical activity and dominant frequency (DF) representing its frequency were analyzed in blocks with a 5-minute duration. We divided the patients into 2 groups, thoracolumbar kyphosis (TLK) and non-TLK groups, and compared them. There were no significant differences between the 2 groups in background data. In the non-TLK group, DPs post 0–5 min were significantly higher than those during pre 5–0 min in channels 1 and 3 (P < 0.05 and P < 0.01). DF deviation in the TLK group was significantly higher than that in the non-TLK group at 10 to 15 postprandial minutes (P < 0.05). Low frequency/high frequency activity measured by HRV, reflecting the activity of the sympathetic nervous system, in the TLK group was significantly lower than that in the non-TLK group while eating (P < 0.01). The EGG of patients with spinal kyphotic deformity showed a similar change to that of patients with GERD; the spinal kyphotic deformity itself may affect gastric electrical activity.

DOI PubMed CiNii Research

Lumbar spinal stenosis associated with progression of locomotive syndrome and lower extremity muscle weakness

Kasukawa Y.

Clinical Interventions in Aging ( Clinical Interventions in Aging ) 14 1399 - 1405 2019年

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Risk factors for proximal junctional fracture following fusion surgery for osteoporotic vertebral collapse with delayed neurological deficits: A retrospective cohort study of 403 patients

Tamai K.

Spine Surgery and Related Research ( Spine Surgery and Related Research ) 3 ( 2 ) 171 - 177 2019年

Introduction: Approximately 3% of osteoporotic vertebral fractures develop osteoporotic vertebral collapse (OVC) with neurological deficits, and such patients are recommended to be treated surgically. However, a proximal junctional fracture (PJFr) following surgery for OVC can be a serious concern. Therefore, the aim of this study is to identify the incidence and risk factors of PJFr following fusion surgery for OVC.Methods: This study retrospectively analyzed registry data collected from facilities belonging to the Japan Association of Spine Surgeons with Ambition (JASA) in 2016. We retrospectively analyzed 403 patients who suffered neurological deficits due to OVC below T10 and underwent corrective surgery; only those followed up for ≥2 years were included. Potential risk factors related to the PJFr and their cut-off values were calculated using multivariate logistic regression analysis and receiver operating characteristic (ROC) analysis.Results: Sixty-three patients (15.6%) suffered PJFr during the follow-up (mean 45.7 months). In multivariate analysis, the grade of osteoporosis (grade 2, 3: adjusted odds ratio (aOR) 2.92; p=0.001) and lower instrumented vertebra (LIV) level (sacrum: aOR 6.75; p=0.003) were independent factors. ROC analysis demonstrated that lumbar bone mineral density (BMD) was a predictive factor (area under curve: 0.72, p=0.035) with optimal cut-off value of 0.61 g/cm2 (sensitivity, 76.5%; specificity, 58.3%), but that of the hip was not (p=0.228).Conclusions: PJFr was found in 16% cases within 4 years after surgery; independent risk factors were severe osteoporosis and extended fusion to the sacrum. The lumbar BMD with cut-off value 0.61 g/cm2 may potentially predict PJFr. Our findings can help surgeons select perioperative adjuvant therapy, as well as a surgical strategy to prevent PJFr following surgery.

DOI CiNii Research

Surgical results of patients with myelopathy due to ossification of the ligamentum flavum with ossification of the posterior longitudinal ligament or a vertebral fracture at the same level of the thoracic spine: A retrospective comparative study

Kasukawa Y.

Asian Spine Journal ( Asian Spine Journal ) 13 ( 5 ) 832 - 841 2019年

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Surgical treatment of osteoporotic vertebral fracture with neurological deficit - A nationwide multicenter study in Japan

Hosogane N.

Spine Surgery and Related Research ( Spine Surgery and Related Research ) 3 ( 4 ) 361 - 367 2019年

Introduction: The prevalence of patients with osteoporosis continues to increase in aging societies, including Japan. The first choice for managing osteoporotic vertebral compression fracture (OVF) is conservative treatment. Failure in conservative treatment for OVF may lead to non-union or vertebral collapse, resulting in neurological deficit and subsequently requiring surgical intervention. This multicenter nationwide study in Japan was conducted to comprehensively understand the outcomes of surgical treatments for OVF non-union.Methods: This multicenter, retrospective study included 403 patients (89 males, 314 females, mean age 73.8 ± 7.8 years, mean follow-up 3.9 ± 1.7 years) with neurological deficit due to vertebral collapse or non-union after OVF at T10-L5 who underwent fusion surgery with a minimum 1-year follow-up. Radiological and clinical outcomes at baseline and at the final follow-up (FU) were evaluated.Results: OVF was present at a thoracolumbar junction such as T12 (124 patients) and L1 (117 patients). A majority of OVF occurred after a minor trauma, such as falling down (55.3%) or lifting objects (8.4%). Short segment fusion, including affected vertebra, was conducted (mean 4.0 ± 2.0 vertebrae) with 256.8 minutes of surgery and 676.1 g of blood loss. A posterior approach was employed in 86.6% of the patients, followed by a combined anterior and posterior (8.7%), and an anterior (4.7%) approach. Perioperative complications and implant failures were observed in 18.1% and 41.2%, respectively. VAS scores of low back pain (74.7 to 30.8 mm) and leg pain (56.8 to 20.7 mm) improved significantly at FU. Preoperatively, 52.6% of the patients were unable to walk and the rate of non-ambulatory patients decreased to 7.5% at FU.Conclusions: This study demonstrated that substantial improvement in activity of daily living (ADL) was achieved by fusion surgery. Although there was a considerable rate of complications, fusion surgery is beneficial for elderly OVF patients with non-union.

DOI CiNii Research

Effects of activated Vitamin D, alfacalcidol, and low-intensity aerobic exercise on osteopenia and muscle atrophy in type 2 diabetes mellitus model rats

Akagawa M.

PLoS ONE ( PLoS ONE ) 13 ( 10 ) 2018年10月

DOI

Intradural extramedullary tumor in the stenotic cervical spine resected through open-door laminoplasty with hydroxyapatite spacers: Report of two cases

Miyakoshi N.

BMC Surgery ( BMC Surgery ) 18 ( 1 ) 2018年06月

DOI

Limaprost or Pregabalin: Preoperative and Postoperative Medication for Pain due to Lumbar Spinal Stenosis

Kasukawa Y.

Pain Practice ( Pain Practice ) 18 ( 5 ) 625 - 630 2018年06月

DOI

Answer to the Letter to the Editor of Jie Weng et al. concerning, “Relationship between preoperative serum rapid turnover proteins and early-stage surgical wound infection after spine surgery” by D. Kudo et al. (Eur Spine J; 2016: doi:10.1007/s00586-016-4855-z)

Kudo D.

European Spine Journal ( European Spine Journal ) 27 ( 5 ) 982 - 984 2018年05月

DOI

mRNA expressions of peroxisome proliferator-activated receptor gamma coactivator 1α, tumor necrosis factor-α, and interleukin-6 in paraspinal muscles of patients with lumbar kyphosis: A preliminary study

Kudo D.

Clinical Interventions in Aging ( Clinical Interventions in Aging ) 13 1633 - 1638 2018年

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Relationship between preoperative serum rapid turnover proteins and early-stage surgical wound infection after spine surgery

Kudo D.

European Spine Journal ( European Spine Journal ) 26 ( 12 ) 3156 - 3161 2017年12月

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Comparison of spinal alignment, muscular strength, and quality of life between women with postmenopausal osteoporosis and healthy volunteers

Miyakoshi N.

Osteoporosis International ( Osteoporosis International ) 28 ( 11 ) 3153 - 3160 2017年11月

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Complications Associated With Spine Surgery in Patients Aged 80 Years or Older: Japan Association of Spine Surgeons with Ambition (JASA) Multicenter Study

Kobayashi K.

Global Spine Journal ( Global Spine Journal ) 7 ( 7 ) 636 - 641 2017年10月

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Risk Factors for Delirium After Spine Surgery in Extremely Elderly Patients Aged 80 Years or Older and Review of the Literature: Japan Association of Spine Surgeons with Ambition Multicenter Study

Kobayashi K.

Global Spine Journal ( Global Spine Journal ) 7 ( 6 ) 560 - 566 2017年09月

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Evaluation of sagittal spine-pelvis-lower limb alignment in elderly women with pelvic retroversion while standing and walking using a three-dimensional musculoskeletal modelw

Sasaki K.

Asian Spine Journal ( Asian Spine Journal ) 11 ( 4 ) 562 - 569 2017年08月

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整形トピックス脊柱後彎変形高齢者における立位・歩行時のモーメントの検討　三次元体幹筋骨格モデルを用いて

佐々木研, 本郷道生, 島田洋一, 巖見武裕

整形外科 ( 南江堂 ) 68 ( 7 ) 638 - 638 2017年07月

DOI CiNii Research

特集医工連携による新たな整形外科治療脊椎モデルシミュレーションの臨床応用

島田洋一, 佐々木研, 巖見武裕, 本郷道生, 宮腰尚久

関節外科 ( (株)メジカルビュー社 ) 36 ( 5 ) 534 - 540 2017年05月

DOI CiNii Research

特集高齢者の脊柱変形Up to Date 第2章　治療高齢者脊柱変形に対する保存療法-胸腰椎部・骨盤:運動療法

本郷道生, 宮腰尚久, 島田洋一

脊椎脊髄ジャーナル ( 三輪書店 ) 30 ( 4 ) 339 - 344 2017年04月

DOI CiNii Research

Relationships among spinal mobility and sagittal alignment of spine and lower extremity to quality of life and risk of falls

Ishikawa Y.

Gait and Posture ( Gait and Posture ) 53 98 - 103 2017年03月

DOI

Kasukawa Y.

Clinical Interventions in Aging ( Clinical Interventions in Aging ) 12 413 - 420 2017年02月

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三次元筋骨格モデルを用いた動的胸腰椎モデルの開発

樋口諒, 小松瞭, 巖見武裕, 飯田純平, 畠山和利, 本郷道生, 島田洋一

ロボティクス・メカトロニクス講演会講演概要集 ( 一般社団法人日本機械学会 ) 2017 ( 0 ) 2P2-J02 2017年

Musculoskeletal modeling of the thoracolumbar spine and trunk muscle are considered clinically useful for quantifying spinal disease processes. However, current models of thoracic spine are not evaluated for dynamical load and posture, or muscle path are constructed Via-Point (straight line muscle) type. In this study, we developed novel trunk musculoskeletal models of the predicted thoracolumbar load which are constructed muscle path in more detail, and validated developed models in dynamic loading and various postures. Developed spine models segmented 17 vertebrae, a sacrum, 10 pairs of ribs, a sternum and defined 17 intervertebral. Muscle path of the trunk muscle models constructed 2 types which are Via-Point type and Wrapping type (curved line muscle along ellipsoid). We estimated intradiscal pressure with constructed models and compared it with measured values. As a result, intradiscal pressure estimated by the model using Wrapping method had an extremely strong correlation with intradiscal pressure measurements made in the thoracic spine. Our results demonstrated significance to faithfully reproduce muscle path in developed musculoskeletal models.

DOI CiNii Research

動的座位バランス計測装置による体幹バランスの定量化

斉藤公男, 島田洋一, 宮腰尚久, 松永俊樹, 巌見武裕, 本郷道生, 粕川雄司, 齊藤英知, 益谷法光, 高橋靖博, 千田聡明, 畠山和利, 渡邉基起, 石川順基, 髙橋裕介, 鈴木真理, 村田脩

リハビリテーション医学 ( 公益社団法人日本リハビリテーション医学会 ) 54 ( 1 ) 31 - 35 2017年

安全にバランス機能を測定するため，動的座位によるバランス計測装置を開発した．本装置は、座面反力（重心動揺）を検出する計測装置と，モータの回転により座面を側方傾斜させ一定の周期で座面を振動させる外乱刺激装置で構成される．3軸力学センサを用い，座面の圧力と圧力中心点を算出することが可能である．座位で計測を行うことで安全であり，下肢の影響を受けないため体幹バランス能力の評価にも使用できると考えている．現在までに行った基礎実験やフィールドワークでの活動，および本装置を用いた介入試験の結果と有用性，今後の活動について概説する．

DOI CiNii Research

Risk factors of cervical surgery related complications in patients older than 80 years

Tamai K.

Spine Surgery and Related Research ( Spine Surgery and Related Research ) 1 ( 4 ) 179 - 184 2017年

Introduction: With an aging population, the proportion of patients aged ≥80 years requiring cervical surgery is increasing. Surgeons are concerned with the high incidence of complications in this population, because "age" itself has been reported as a strong risk factor for complications. However, it is still unknown which factors represent higher risk among these elderly patients. Therefore, this study was conducted to identify the risk factors related to surgical complications specific to elderly patients by analyzing the registry data of patients aged ≥80 years who underwent cervical surgery.Methods: We retrospectively studied multicenter collected registry data using multivariate analysis. Sixty-six patients aged ≥80 years who underwent cervical surgery and were followed up for more than one year were included in this study. Preoperative patient demographic data, including comorbidities and postoperative complications, were collected from multicenter registry data. Complications were considered as major if they required invasive intervention, caused prolonged morbidity, or resulted in prolongation of hospital stay. Logistic regression analysis was performed to analyze the risk factors for complications. A p-value of <0.05 was considered as statistically significant.Results: The total number of patients with complications was 21 (31.8%), with seven major (10.6%) and 14 minor (21.2%) complications. Multivariate logistic regression analysis, after adjusting for age, revealed two significant risk factors: preoperative cerebrovascular disorders (OR, 6.337; p=0.043) for overall complications and cancer history (OR, 8.168; p=0.021) for major complications. Age, presence of diabetes mellitus, and diagnosis were not significant predictive factors for complications in this study.Conclusions: Preoperative cerebrovascular disorders and cancer history were risk factors for complications after cervical surgery in patients over 80 years old. Surgeons should pay attention to these specific risk factors before performing cervical surgery in elderly patients.

DOI CiNii Research

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