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Affiliation |
Doctorial Course in Health Sciences Physical Therapy |
HONGO Michio
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Graduating School 【 display / non-display 】
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-1998.03
Akita University Faculty of Medicine Graduated
Graduate School 【 display / non-display 】
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-1998.03
Akita University Graduate School,Division of Medicine Doctor's Course Completed
Campus Career 【 display / non-display 】
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2023.04-Now
Akita University Doctorial Course in Health Sciences Physical Therapy Professor
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2022.03-2023.03
Akita University Graduate School of Medicine Doctorial Course in Medicine Organ Function-Oriented Medicine Department of Orthopedic Surgery Associate Professor
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2009.04-2022.02
Akita University Hospital Orthopedic Surgery Lecturer
Thesis for a degree 【 display / non-display 】
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Surface strain distribution on thoracic and lumbar vertebrae under axial compression. The role in burst fractures
Hongo M, Abe E, Shimada Y, Murai H, Ishikawa N, Sato K
Spine 1998.03
Domestic Co-author
Research Achievements 【 display / non-display 】
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Cost-Effectiveness of Monotherapy versus Polypharmacy in Cervicobrachial Symptoms: A Nationwide Multicenter Analysis
Ito Sadayuki, Nakashima Hiroaki, Wakao Norimitsu, Furuya Takeo, Yoshii Toshitaka, Arima Hideyuki, Yamato Yu, Imagama Shiro, Imajo Yasuaki, Miyamoto Hiroshi, Inoue Gen, Miyagi Masayuki, Kanbara Shunsuke, Iizuka Yoichi, Chikuda Hirotaka, Watanabe Kei, Kobayashi Kazuyoshi, Tsushima Mikito, Miyazaki Masashi, Yagi Mitsuru, Suzuki Satoshi, Takahata Masahiko, Hongo Michio, Koda Masao, Nagata Keiji, Mori Kanji, Suzuki Akinobu, Kaito Takashi, Murotani Kenta, Miyakoshi Naohisa, Hashizume Hiroshi, Matsuyama Yukihiro, Kawakami Mamoru, Haro Hirotaka, The Project Committee of the Japanese Society for Spine Surgery and Related Research (JSSR)
Spine Surgery and Related Research ( 一般社団法人 日本脊椎脊髄病学会 ) advpub ( 0 ) 2026
<p><b>Introduction: </b>Cervicobrachial symptoms are common causes of disability worldwide, yet the cost-effectiveness of combination therapy versus monotherapy remains unclear. In this nationwide multicenter study, we aimed to compare the economic value of multiple-drug therapy with that of monotherapy for cervicobrachial symptoms.</p><p><b>Methods: </b>This prospective observational study, conducted through the Japanese Society for Spine Surgery and Related Research, included 261 adults with cervicobrachial symptoms across 28 institutions (July 2020 to July 2022). Patients received monotherapy (n = 112) or multiple-drug therapy (n = 149) using five pre-specified agents: loxoprofen, celecoxib, acetaminophen, tramadol–acetaminophen, and pregabalin. The primary outcome was quality-adjusted life years (QALYs), calculated from monthly EuroQol 5-Dimension 5-Level assessments over six months. The secondary outcomes were drug costs and incremental cost-effectiveness ratios (ICERs), evaluated against Japan's reference threshold of ¥5,000,000 per QALY.</p><p><b>Results: </b>Mean QALY gains were similar between the monotherapy (0.00267 ± 0.00544) and multiple-drug therapy (0.00284 ± 0.00774) groups, with no statistically significant difference (p > 0.05). However, total drug costs were substantially higher with multiple-drug therapy (¥19,243 vs. ¥8,275). ICERs were more favorable for monotherapy (¥3,093,957/QALY) than for multiple-drug therapy (¥6,781,101/QALY). Among agents used as monotherapy, loxoprofen (¥744,409/QALY) and acetaminophen (¥781,293/QALY) showed the most favorable cost-effectiveness profiles, whereas tramadol–acetaminophen (¥6,370,451/QALY) and pregabalin (¥10,995,651/QALY) had the least favorable cost-effectiveness. Most QALY gains occurred during the first three months in both groups.</p><p><b>Conclusions: </b>Multiple-drug therapy approximately doubled pharmaceutical costs without providing additional QALY gains over six months. Monotherapy, particularly with non-steroidal anti-inflammatory drugs or acetaminophen, offers superior cost-effectiveness and should be prioritized as first-line treatment. These findings underscore the need for restraint in polypharmacy and provide real-world evidence to guide clinical decision-making and national healthcare policy.</p>
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Ohtaka Maiko, Saito Akira, Hongo Michio, Matsuzaki Masashi
The Journal of Physical Fitness and Sports Medicine ( 一般社団法人日本体力医学会 ) advpub ( 0 ) 2026
<p>This study aimed to evaluate a musculoskeletal screening method for elementary school students using ultrasound and lower limb flexibility assessments, with the goal of early detection of Osgood-Schlatter disease during the growth period. A total of 143 boys in the fourth to sixth grades of elementary school from a single prefecture underwent musculoskeletal screening between November 2021 and February 2023. Using a diagnostic ultrasound device, the tibial tuberosity was observed, and its developmental stage was classified based on Ehrenborg’s four-stage classification (Ehrenborg G and Lagergren C. 1961. <i>Acta Chir Scand</i> 121: 315–327). The presence of Osgood-Schlatter disease was determined based on the presence of irregularities in the ultrasound image. Lower limb flexibility was assessed quantitatively using finger-floor distance (FFD) and heel-hip distance (HHD). The cartilaginous stage (C stage) was the most common developmental stage observed. Osgood-Schlatter disease was identified in eight children (5.6%) and was found only in the epiphyseal (E) and bony (B) stages (<i>p</i> = 0.004, φ = 0.308). HHD was significantly greater in the Osgood-Schlatter group (<i>p</i> = 0.040, r = 0.680). In some children without knee pain or tenderness, irregularities in the tibial tuberosity were detected on ultrasound imaging, suggesting that ultrasound imaging may be useful for the early detection of asymptomatic lesions. This screening approach, which combines ultrasound examination and flexibility assessment, is expected to serve as a novel method for the early detection and prevention of musculoskeletal disorders in children during their growth period. Further large-scale studies and continued investigation into methods for assessing flexibility in growing children are warranted.</p>
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Collaboration between orthopedic surgeons and physical therapists in exercise therapy for chronic low back pain: current situation and problems
Hongo Michio, Saito Akira, Kasukawa Yuji, Miyakoshi Naohisa
Journal of Spine Research ( The Japanese Society for Spine Surgery and Related Research ) 16 ( 6 ) 837 - 842 2025.06
<p>Exercise therapy plays a crucial role in functional recovery and improving patients' quality of life in the treatment of low back pain. Orthopedic surgeons diagnose the cause of low back pain through examinations and prescribe appropriate exercise therapy, but collaboration with physical therapists is essential for effective implementation. Orthopedic surgeons identify the cause of low back pain through patient interviews, physical examinations, and imaging studies to determine the most appropriate treatment. In exercise therapy, personalized prescriptions based on an accurate diagnosis are required. However, evidence supporting exercise therapy tailored to specific causes of back pain remains limited, posing a challenge for future research. Meanwhile, the effectiveness of exercise therapy for chronic low back pain is recommended in clinical guidelines, with aerobic exercise and core stabilization training being recognized as beneficial. Physical therapists, based on the diagnosis provided by orthopedic surgeons, conduct detailed evaluations and implement tailored treatments for patients. They utilize a combination of manual therapy, stretching, and core muscle training to alleviate back pain. Additionally, they contribute to the prevention of low back pain through lifestyle guidance and workplace education. Particularly, combining exercise with educational interventions is expected to yield greater preventive effects. However, collaboration between orthopedic surgeons and physical therapists faces challenges such as insufficient information sharing and issues with treatment continuity. To address these problems, utilizing ICT for real-time communication, organizing conferences, and implementing interdisciplinary training programs can be effective strategies. Strengthening cooperation at every stage of diagnosis, treatment, and education is essential for enhancing the effectiveness of low back pain management.</p>
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Development of a New Focal Mouse Model of Bone Metastasis in Renal Cell Carcinoma
OYA KEITA, TSUCHIE HIROYUKI, NAGASAWA HIROYUKI, HONGO MICHIO, KASUKAWA YUJI, KUDO DAISUKE, SHOJI RYO, KASAMA FUMIHITO, KAWARAGI TAKASHI, WATANABE MANABU, TOMINAGA KENTA, MIYAKOSHI NAOHISA
In Vivo ( Production services Kyorinsha Co., Ltd. ) 38 ( 3 ) 1074 - 1078 2024
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Wakabayashi Rena, Hongo Michio, Misawa Akiko, Kimura Ryota, Kudo Daisuke, Shimada Yoichi, Miyakoshi Naohisa
Journal of Spine Research ( The Japanese Society for Spine Surgery and Related Research ) 14 ( 11 ) 1377 - 1382 2023.11
<p><b>Introduction: </b>Brace treatment for adolescent idiopathic scoliosis (AIS) is usually indicated for patients with Risser sign grade 0-3, but not for above grade 4. However, we occasionally see patients whose curves progress even in patients with Risser sign grade 4. We examine Cobb angle progression and risk factors in Risser sign grade 4 cases of AIS.</p><p><b>Methods: </b>From January 2016 to December 2020, 42 AIS patients with Risser sign grade 4 at the first visit to our clinic and were followed up for at least 1 year were included. Patient background, physical findings, and radiological measurements including the Cobb angles were evaluated. Patients were divided into progressive and non-progressive groups to compare their risk factors of scoliosis.</p><p><b>Results: </b>Eight patients were in the progressive group and 34 were in the non-progressive group. In the progressive group, the Cobb angle increased by 7.1 degrees, from 28.7 to 35.8 degrees. The time since menarche was significantly shorter in the progressive group (9.7 months) than in the non-progressive group (24.2 months) (P=0.003). Growth in height was significantly greater in the progressive group (+2.9 cm) than in the non-progressive group (+1.8 cm) (P = 0.02). There were no differences in the other factors.</p><p><b>Conclusions: </b>In this study, curves progressed in approximately 20% of patients with Risser sign grade 4. In cases with short time since menarche or potential for height growth, AIS patients with Risser sign grade 4 may need to take brace therapy.</p>