Affiliation |
Graduate School of Medicine Doctorial Course in Medicine Organ Function-Oriented Medicine Department of Pediatrics |
TAKAHASHI Tsutomu
|
|
Graduating School 【 display / non-display 】
-
1979.04-1986.03
Akita University Faculty of Medicine Graduated
Graduate School 【 display / non-display 】
-
-1993.03
Akita University Graduate School, Division of Medical Science Doctor's Course Completed
Campus Career 【 display / non-display 】
-
2009.04-Now
Akita University Graduate School of Medicine Doctorial Course in Medicine Organ Function-Oriented Medicine Professor
Research Achievements 【 display / non-display 】
-
Evidence for the association of ultraviolet-C and H(2)O(2)-induced apoptosis with acid sphingomyelinase activation
Komatsu M, Takahashi T, Abe T, Takahashi I, Ida H, Takada G
Biochim Biophys Acta 1533 ( 1 ) 47 - 54 2001.01 [Refereed]
Research paper (journal)
-
A new locus for a dominant form of multinodular goiter on 3q26.1-q26.3
Takahashi T, et al.
BBRC 284 2001.01 [Refereed]
Research paper (journal) Domestic Co-author
-
Active hypothalamus-pituitary-gonadal axis in an infant with adrenal hypoplasia congenita
Takahashi T, et al.
J Pediatr 130 1997.01 [Refereed]
Research paper (journal) Domestic Co-author
-
Identification and expression of five mutations in the human acid sphingomyelinase gene causing types A and B Niemann-Pick disease. Molecular evidence for genetic heterogeneity in the neuronopathic and non-neuronopathic forms.
Takahashi T, Suchi M, Desnick RJ, Takada G, Schuchman EH
J Biol Chem 267 ( 18 ) 12552 - 8 1992.01 [Refereed]
Research paper (journal)
-
Biological and Pharmaceutical Bulletin ( The Pharmaceutical Society of Japan ) 43 ( 9 ) 1398 - 1406 2020.09
-
Takahashi Kiichi, Adachi Hiroyuki, Ito Masato, Kato Akie, Hebiguchi Taku, Takahashi Tsutomu
Journal of Japan Society of Perinatal and Neonatal Medicine ( Japan Society of Perinatal and Neonatal Medicine ) 56 ( 2 ) 335 - 342 2020
<p> <i>Enterobacter cloacae</i>, a gram-negative bacillus, is a member of the normal gut microbiota; however, it is often highly virulent in neonates. Notably, neurological sequelae of meningitis may occur despite the administration of systemic antibiotics. We describe a female neonate weighing 2,309 g born at 33 weeks and 4 days of gestation who developed <i>E. cloacae</i> meningitis and ventriculitis after undergoing surgery for jejunal atresia. She developed severe cerebral necrosis despite treatment with high-dose carbapenem. We speculated that bacterial translocation of <i>E. cloacae</i> secondary to surgical injury caused meningitis and ventriculitis. <i>E. cloacae</i> can rapidly colonize the gut in neonates soon after birth; therefore, early identification of this highly pathogenic organism is important to initiate prompt and optimal infection control measures, particularly in neonates undergoing gastrointestinal surgery.</p>