TAKAMURA Hiroyoshi

写真a

Affiliation

Graduate School of Engineering Science  Department of Life Science  Life Science Course 

Mail Address

E-mail address

Research Interests 【 display / non-display 】

  • 天然物合成

  • 生物付着

  • 生物活性分子

  • 有機合成化学

Graduating School 【 display / non-display 】

  •  
    -
    2000.03

    Tohoku University   Faculty of Science   Graduated

Graduate School 【 display / non-display 】

  •  
    -
    2005.03

    Tohoku University  Graduate School, Division of Natural Science  Doctor's Degree Program  Completed

  •  
    -
    2002.03

    Tohoku University  Graduate School, Division of Natural Science  Master's Degree Program  Completed

Campus Career 【 display / non-display 】

  • 2026.09
    -
    Now

    Akita University   Graduate School of Engineering Science   Department of Life Science   Life Science Course   Associate Professor  

External Career 【 display / non-display 】

  • 2023.04
    -
    2026.08

    Okayama University   Associate Professor  

  • 2021.04
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    2023.03

    Okayama University   Associate Professor  

  • 2015.03
    -
    2021.03

    Okayama University   Graduate School of Natural Science and Technology   Associate Professor  

Research Areas 【 display / non-display 】

  • Nanotechnology/Materials / Synthetic organic chemistry

 

Research Achievements 【 display / non-display 】

    ◆Original paper【 display / non-display 】

  • Photochemical Macrolactonization of Hydroxyaldehydes via C–H Bromination

    Sakura Kodaki, Haru Ando, Hiroyoshi Takamura, Isao Kadota, Kenta Tanaka

    Precision Chemistry ( American Chemical Society (ACS) )    2025.11  [Refereed]

    Research paper (journal)  

    DOI

  • The Direct Photochemical Cross-Esterification of Alcohols via Site-Selective C-H Bromination

    Atsuya Miyamoto, Hiroyoshi Takamura, Isao Kadota, Kenta Tanaka

    Chemical Communications ( Royal Society of Chemistry (RSC) )  61 ( 89 ) 17364 - 17367   2025.10  [Refereed]

    Research paper (journal)  

    We have developed a direct photochemical cross-esterification of alcohols that proceeds via the in-situ generation of acyl bromides. The C-H bond of a benzyl alcohol is selectively activated by a...

    DOI

  • Generation of alkyl radicals via C(sp3)–C(sp3) bond cleavage of xanthene-based precursors for photocatalytic Giese-type reaction

    Shuta Horiuchi, Masato Oishi, Asuka Mizutani, Hiroyoshi Takamura, Isao Kadota, Kenta Tanaka

    Chemical Communications ( Royal Society of Chemistry (RSC) )  61 ( 84 ) 16376 - 16379   2025.09  [Refereed]

    Research paper (journal)  

    Novel xanthene-based alkyl radical precursors were developed and subjected to photocatalytic C(sp<sup>3</sup>)–C(sp<sup>3</sup>) bond cleavage for the efficient generation of alkyl radicals, which were reacted with various alkenes to afford the Giese-type products.

    DOI

  • Recent progress on phenothiazine organophotoredox catalysis

    Kenta Tanaka, Hiroyoshi Takamura, Isao Kadota

    Tetrahedron Letters ( Elsevier BV )  169   155745   2025.07  [Refereed]  [Invited]

    Research paper (journal)  

    DOI

  • Redox-potential-controlled intermolecular [2 + 2] cycloaddition of styrenes for the regio- and diastereoselective synthesis of multisubstituted halogenocyclobutanes

    Asuka Mizutani, Momo Kondo, Shoko Itakura, Hiroyoshi Takamura, Yujiro Hoshino, Makiya Nishikawa, Isao Kadota, Kosuke Kusamori, Kenta Tanaka

    Bulletin of the Chemical Society of Japan ( Oxford University Press (OUP) )  98 ( 6 ) uoaf044   2025.05  [Refereed]

    Research paper (journal)  

    Abstract

    The redox potential is an important factor for controlling the outcome of photoredox catalysis. Particularly, the selective oxidation of substrates and the control over the reactions are challenging when using photoredox catalysts that have high excited-state reduction potentials. In this study, a redox-potential-controlled intermolecular [2 + 2] cycloaddition of styrenes using a thioxanthylium organophotoredox (TXT) catalyst has been developed. This TXT catalyst selectively oxidizes β-halogenostyrenes and smoothly promotes the subsequent intermolecular [2 + 2] cycloadditions to give multisubstituted halogenocyclobutanes with excellent regio- and diastereoselectivity, which has not been effectively achieved by the hitherto reported representative photoredox catalysts. The synthesized halogenocyclobutanes exhibit interesting free radical scavenging activity. The present reaction contributes to the field of redox-potential-controlled electron transfer chemistry.

    DOI

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    ◆Other【 display / non-display 】

  • Development of the Novel Antifouling Agent based on Organic Synthesis

    高村浩由, 遠藤紀之

    Annual Report of the Okayama Foundation for Science and Technology   ( 26 )   2017

    J-GLOBAL

Books 【 display / non-display 】

Presentations 【 display / non-display 】

  • Redox Potential Controlled Intermolecular [2+2] Cycloadditions for the Synthesis of Halocyclobutanes via Organophotoredox Catalysis

    Asuka Mizutani, Kenta Tanaka, Hiroyoshi Takamura, Isao Kadota

    10th German Japanese Symposium on Electrosynthesis  2023.06  -  2023.06 

  • Moderately Oxidizing Thioxanthylium Organophotoredox Catalysts for Radical-Cation Diels–Alder Reactions

    Kenta Tanaka, Mami Kishimoto, Naoya Ohtsuka, Toshiyasu Suzuki, Norie Momiyama, Hiroyoshi Takamura, Isao Kadota, Yujiro Hoshino

    10th German Japanese Symposium on Electrosynthesis  2023.06  -  2023.06 

  • Efficient Synthesis of Ozonides under Dry Conditions

    Mohamed R. El-kholany, Nana Kishimoto, Kenta Tanaka, Hiroyoshi Takamura, Isao Kadota

    The 103rd CSJ Annual Meeting  2023.03  -  2023.03 

  • Synthetic Approach toward the Structural Elucidation of Natural Products

    Hiroyoshi Takamura  [Invited]

    Sakura Science Program  2022.01  -  2022.01 

  • Formal Total Syntheses of Enigmazole A and Neopeltolide

    2018.09  -  2018.09 

 

Academic Activity 【 display / non-display 】

  • 2025
     
     

  • 2024
     
     

  • 2019
     
     

  • 2018
    -
    2022

  • 2014
     
     

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Media Report 【 display / non-display 】

  • https://www.eurekalert.org/news-releases/1108112

  • https://www.okayama-u.ac.jp/tp/release/release_id1465.html

  • https://sj.jst.go.jp/news/202504/n0418-03k.html

  • https://www.keguanjp.com/kgjp_keji/kgjp_kj_sea/pt20250408000012.html

  • https://www.agara.co.jp/article/470506

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