研究等業績 - 原著論文 - 渡邊 健太
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Watanabe K.
The American journal of gastroenterology ( The American journal of gastroenterology ) 116 ( 8 ) 1632 - 1637 2021年08月 [査読有り]
研究論文（学術雑誌）
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So Kodama, Kenta Watanabe, et al.
Esophagus ( Esophagus ) 2025年03月 [査読有り]
研究論文（学術雑誌）
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Sho Fukuda, Kenta Watanabe, et al.
Journal of Gastroenterology ( Journal of Gastroenterology ) 2025年02月 [査読有り]
研究論文（学術雑誌） 国内共著
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Kenta Watanabe, et al.
Journal of Gastroenterology and Hepatology ( Journal of Gastroenterology and Hepatology (Australia) ) 40 ( 3 ) 609 - 617 2024年12月 [査読有り]
研究論文（学術雑誌） 国内共著
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Yuki Wada, Satoshi Kumagai, Noriko Takagi, Tetsugaku Shinozaki, Toshiki Murata, Daichi Sugawara, Kenta Watanabe, Tamotsu Matsuhashi, Katsunori Iijima, Naoko Mori
Journal of Gastroenterology ( Journal of Gastroenterology ) 60 ( 1 ) 32 - 42 2024年10月 [査読有り]
研究論文（学術雑誌）
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Sho Fukuda, Kenta Watanabe, et al.
Journal of Gastroenterology ( Journal of Gastroenterology ) 59 ( 10 ) 887 - 895 2024年08月 [査読有り]
研究論文（学術雑誌） 国内共著
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Development of a prediction score for Barrett's esophagus in Japanese health checkup settings
So Kodama, Kenta Watanabe, et al.
Esophagus ( Esophagus ) 21 ( 4 ) 552 - 562 2024年08月 [査読有り]
研究論文（学術雑誌） 国内共著
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Risk stratification of synchronous gastric cancers including alcohol-related genetic polymorphisms
Sho Asonuma, Waku Hatta, Tomoyuki Koike, Hideki Okata, Kaname Uno, Wataru Iwai, Masashi Saito, Makoto Yonechi, Daisuke Fukushi, Shoichi Kayaba, Ryosuke Kikuchi, Hirotaka Ito, Jun Fushiya, Ryuhei Maejima, Yasuhiko Abe, Masashi Kawamura, Junya Honda, Yutaka Kondo, Naohiro Dairaku, Shusuke Toda, Kenta Watanabe, Kiichi Takahashi, Hiroharu Echigo, Yasuaki Abe, Hiroyuki Endo, Tomoki Okata, Tatsuya Hoshi, Kenji Kinoshita, Madoka Kisoi, Tomohiro Nakamura, Naoki Nakaya, Katsunori Iijima, Atsushi Masamune
Journal of Gastroenterology and Hepatology ( Journal of Gastroenterology and Hepatology (Australia) ) 39 ( 8 ) 1554 - 1562 2024年04月 [査読有り]
研究論文（学術雑誌） 国内共著
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Katsunori Iijima, Kenta Watanabe, Yosuke Shimodaira, Shigeto Koizumi, Sho Fukuda, Tatsuki Yoshida, Ryo Ookubo, Tamotsu Matsuhashi, Mario Jin, Masahito Miura, Hiroyuki Shibata
The Tohoku Journal of Experimental Medicine ( 東北ジャーナル刊行会 ) advpub ( 0 ) 161 - 168 2024年04月 [査読有り]
研究論文（学術雑誌）
<p>The long-term impact of the coronavirus disease 2019 (COVID-19) pandemic on the disruption of gastrointestinal cancer diagnoses remains unclear. This study investigated the actual impact on esophagogastric cancer (EGC) and colorectal cancer (CRC) diagnoses up to the third year of the pandemic in Akita Prefecture, Japan, using population-based registry data. We collected data on the annual number of EGC and CRC diagnoses using a database from the collaborative Akita Prefecture hospital-based registration. The net number of cancers diagnosed in the first three years of the pandemic (2020-2022) were compared with those diagnosed in the three years before the pandemic (2017-2019). Changes in the proportion of cancer stage and initial treatment for diagnosed EGC and CRC after the pandemic were then compared. The total number of EGCs was 9.3% lower in the first three years of the pandemic than in the three years before, probably due to its long-term declining trend. The total number of CRCs in the first three years of the pandemic exceeded that in the three years before, suggesting successful recovery of the diagnostic procedure. The proportion of cancer stages and initial treatment for EGCs and CRCs remained largely unchanged after the onset of the pandemic. Based on the population-based registry data from the first three years of the pandemic, the disruption of gastrointestinal cancer diagnoses caused by the pandemic is settling down without any substantial disease progression, even in Akita Prefecture, the area with the highest incidence of cancer in all of Japan.</p>
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So Takahashi, Kenta Watanabe, et al.
Cancers ( Cancers ) 16 ( 4 ) 2024年02月 [査読有り] [招待有り]
研究論文（学術雑誌） 国内共著
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Disproportionate cancer worries in ultra-short-segment Barrett's esophagus in Japan
Sho Fukuda, Kenta Watanabe, et al.
DEN Open ( DEN Open ) 4 ( 1 ) 2024年01月 [査読有り]
研究論文（学術雑誌） 国内共著
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Kenta Watanabe, Tsuyotoshi Tsuji, Yohei Saruta, Hisanori Matsuzawa, Yosuke Shimodaira, Katsunori Iijima
Digestion ( Digestion ) 105 ( 2 ) 131 - 139 2023年11月 [査読有り]
研究論文（学術雑誌） 国内共著
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Yohei Saruta, Kenta Watanabe, Tsuyotoshi Tsuji, Yasutaka Takahashi, Hisanori Matsuzawa, Tatsuki Yoshida, So Takahashi, Yosuke Shimodaira, Tamotsu Matsuhashi, Katsunori Iijima
Journal of Gastroenterology and Hepatology ( Journal of Gastroenterology and Hepatology (Australia) ) 38 ( 6 ) 940 - 947 2023年03月 [査読有り]
研究論文（学術雑誌） 国内共著
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Waku Hatta, Tomoyuki Koike, Sho Asonuma, Hideaki Okata, Kaname Uno, Tomoyuki Oikawa, Wataru Iwai, Makoto Yonechi, Daisuke Fukushi, Shoichi Kayaba, Ryosuke Kikuchi, Motoki Ohyauchi, Jun Fushiya, Ryuhei Maejima, Yasuhiko Abe, Masashi Kawamura, Junya Honda, Yutaka Kondo, Naohiro Dairaku, Kazuaki Norita, Kenta Watanabe, Kiichi Takahashi, Hiroharu Echigo, Yasuaki Abe, Hiroyuki Endo, Tomoki Okata, Tatsuya Hoshi, Tomohiro Nakamura, Naoki Nakaya, Katsunori Iijima, Atsushi Masamune
Journal of Gastroenterology ( Journal of Gastroenterology ) 58 ( 5 ) 433 - 443 2023年02月 [査読有り]
研究論文（学術雑誌） 国内共著
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Iijima Katsunori, Shimodaira Yosuke, Watanabe Kenta, Koizumi Shigeto, Matsuhashi Tamotsu, Jin Mario, Miura Masahito, Onochi Kengo, Yamai Kiyonori, Fujishima Yuko, Ajimine Takuma, Tsuda Hidehiko, Tsuji Tsuyotoshi, Matsushita Hiro-o, Horikawa Yohei, Dohmen Takahiro, Shibata Hiroyuki
The Tohoku Journal of Experimental Medicine ( 東北ジャーナル刊行会 ) advpub ( 0 ) 301 - 306 2023年 [査読有り]
研究論文（学術雑誌）
<p>We recently reported the decrease in the number of gastrointestinal (GI) cancer diagnoses in 2020 due to disturbance of the healthcare system by the coronavirus disease 2019 (COVID-19) pandemic, using a hospital-based cancer registration system in Akita prefecture, Japan. In this study, we extended the research by showing the latest data (2021) on the number of cancers and examinations. Information on the occurrence and stage of esophageal, gastric, and colorectal cancers was collected from the same database. The number of GI examinations (cancer screening procedures and endoscopic examinations) was also investigated. Following the immediate decrease in the numbers of both GI examinations and GI cancer diagnoses in 2020, a rebound increase in the numbers of GI cancer diagnoses—especially colorectal cancers—was observed in 2021, resulting from an increased number of GI examinations i.e., the total number of colorectal cancers in 2021 increased by 9.0% and 6.8% in comparison to 2020 and pre-pandemic era, respectively. However, the rebound increase in 2021 was largely due to an increase in early-stage cancers, and there was no apparent trend toward the increased predominance of more advanced cancers. It therefore seems that we managed to escape from the worst-case scenario of disturbance of the healthcare system due to pandemic (i.e., an increase in the number of more advanced cancers due to delayed diagnoses). We need to continue to watch the trends in Akita prefecture, which has the highest rate of mortality from the 3 major GI cancers in Japan.</p>
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Shimodaira Y.
Scientific Reports ( Scientific Reports ) 12 ( 1 ) 2022年12月 [査読有り]
研究論文（学術雑誌）
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Usefulness of the CHAMPS score for risk stratification in lower gastrointestinal bleeding
Tajika M.
Scientific Reports ( Scientific Reports ) 12 ( 1 ) 2022年12月 [査読有り]
研究論文（学術雑誌）
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Nature and Clinical Outcomes of Acute Hemorrhagic Rectal Ulcer
Takahashi Y.
Diagnostics ( Diagnostics ) 12 ( 10 ) 2022年10月 [査読有り]
研究論文（学術雑誌）
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Watanabe K.
Esophagus ( Esophagus ) 19 ( 3 ) 477 - 485 2022年07月 [査読有り]
研究論文（学術雑誌）
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Inflammatory Bowel Disease Triggered by BNT162b2 mRNA Vaccination for SARS-CoV-2
Shimodaira Y.
Inflammatory bowel diseases ( Inflammatory bowel diseases ) 28 ( 6 ) 2022年06月
研究論文（学術雑誌）
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Iijima K.
Tohoku Journal of Experimental Medicine ( Tohoku Journal of Experimental Medicine ) 257 ( 1 ) 65 - 71 2022年05月 [査読有り]
研究論文（学術雑誌）
<p>Disruption of cancer screening programs and diagnoses of gastrointestinal cancers by the COVID-19 pandemic has been reported; however, little attention has been paid to the situation in depopulated areas with low infection rates. Akita Prefecture is one of the most depopulated areas of Japan and has the lowest COVID-19 infection rate per capita; at the same time, the prefecture has been top-ranked for mortality due to gastrointestinal cancer for years. In this population-based study in Akita Prefecture, we investigated the occurrence of gastrointestinal cancers and the number of cancer screening procedures over the five-year period of 2016-2020, employing a database from the collaborative Akita Prefecture hospital-based registration system of cancers. The occurrence of gastrointestinal cancers, especially esophago-gastric cancers, declined by 11.0% in 2020, when the COVID-19 pandemic affected the overall healthcare system, compared with the average of 2016-2019. Nonetheless, the occurrence of advanced-stage (stage IV) esophago-gastric cancers increased by 7.2% in 2020. The decrease in the gastrointestinal cancer diagnosis rate in 2020 coincided with a 30% decline in the total number of regular population-based screening programs. Under the ongoing COVID-19 pandemic, cancer screening was uniformly suspended throughout Japan. Accordingly, the COVID-19 pandemic has substantially disrupted the cancer screening system, leading to delays in diagnoses of gastrointestinal cancer, even in depopulated areas (Akita Prefecture) of Japan with a low prevalence of infection. Suspension of cancer screening procedures during an infectious disease pandemic should be thoroughly considered for each region based on the cancer incidence and infection status in that area.</p>
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Fukuda S.
Digestive Endoscopy ( Digestive Endoscopy ) 34 ( 4 ) 757 - 765 2022年05月 [査読有り]
研究論文（学術雑誌）
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Watanabe K.
Scandinavian Journal of Gastroenterology ( Scandinavian Journal of Gastroenterology ) 57 ( 12 ) 1463 - 1469 2022年 [査読有り]
研究論文（学術雑誌）
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Shimodaira Y.
Scandinavian Journal of Gastroenterology ( Scandinavian Journal of Gastroenterology ) 57 ( 2 ) 165 - 168 2022年 [査読有り]
研究論文（学術雑誌）
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Takahashi S.
Digestive Diseases and Sciences ( Digestive Diseases and Sciences ) 68 ( 5 ) 2050 - 2060 2022年 [査読有り]
研究論文（学術雑誌）
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Norita K.
Digestive Endoscopy ( Digestive Endoscopy ) 33 ( 7 ) 1085 - 1092 2021年11月 [査読有り]
研究論文（学術雑誌）
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Kikuchi H.
Esophagus ( Esophagus ) 18 ( 2 ) 380 - 387 2021年04月 [査読有り]
研究論文（学術雑誌）
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Shimodaira Y.
Intestinal Research ( Intestinal Research ) 19 ( 2 ) 225 - 231 2021年04月 [査読有り]
研究論文（学術雑誌）
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Shimodaira Y.
Tohoku Journal of Experimental Medicine ( Tohoku Journal of Experimental Medicine ) 255 ( 1 ) 33 - 39 2021年 [査読有り]
研究論文（学術雑誌）
<p>The onset age of ulcerative colitis has been increasing in several countries. Furthermore, the number of elderly patients with ulcerative colitis has been increasing in an aging society. We investigated the incidence of ulcerative colitis patients in Japan using a large-scale health insurance claims database to survey the ulcerative colitis incidence ratio and the clinical characteristics in late-onset ulcerative colitis patients. Newly diagnosed 2,791 ulcerative colitis between 2015 and 2018 was investigated. Medical treatment within 12 months of diagnosis was analyzed among 0-19, 20-39, 40-59 and 60-75 age groups. The mean age at diagnosis was 40.3 years (SD: 12.9), and the incidence ratio peaked in the 40’s. Most of patients received 5-aminocylitic acid (91.7%), a subset of patients received prednisolone (20.1%), and a small number of patients took immunomodulator (6.8%), cytapheresis (3.3%), anti-TNF<i>α</i> therapy (4.3%), and colectomy (1.0%) within 12 months after diagnosis. All treatments except colectomy were most frequent in the 0-19 age group; however, colectomy was most frequent in 60-75 age group.<b> </b>The clinical course of ulcerative colitis that developed in adults did not differ significantly in terms of medical treatment within 12 months from the onset; meanwhile, the surgery rate was high in elderly patients. It is necessary to pay close attention to future trends regarding the aging of the onset age and the treatment, especially for late-onset ulcerative colitis patients.</p>
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Fukuda S.
Digestion ( Digestion ) 101 ( 1 ) 31 - 37 2020年01月 [査読有り]
研究論文（学術雑誌）