|
所属 |
附属病院 第三内科 |
研究等業績 【 表示 ／ 非表示 】
-
Nara M.
Clinical Nephrology ( Clinical Nephrology ) 98 ( 3 ) 135 - 146 2022年09月
-
Saito M.
Clinical and Experimental Nephrology ( Clinical and Experimental Nephrology ) 26 ( 8 ) 760 - 769 2022年08月
-
Adult-onset Still's Disease during Pregnancy Treated with Tocilizumab
Imaizumi C.
Internal Medicine ( Internal Medicine ) 61 ( 20 ) 3137 - 3140 2022年
<p>A 28-year-old woman exhibited a spiking fever, arthritis, and liver disfunction when she was 22 weeks pregnant. She was diagnosed with adult-onset Still's disease (AOSD). As her condition was resistant to corticosteroid therapy, tocilizumab (TCZ) was selected. The TCZ treatment was effective, and she delivered a healthy child while receiving TCZ treatment. Cases in which AOSD first arises during pregnancy are rare, and there have been no reports of TCZ treatment for AOSD being initiated during pregnancy. Although the safety of TCZ treatment during pregnancy has not been established, it may be effective against severe AOSD that develops during pregnancy. </p>
-
Nara M.
Internal Medicine ( Internal Medicine ) 60 ( 18 ) 2985 - 2989 2021年
<p>There are an increasing number of reports on the safe use of rituximab (RTX), a chimeric anti-CD20 monoclonal antibody, in pregnant women with hematological malignancies or refractory autoimmune diseases. In 2014, the use of RTX for patients with complicated steroid-dependent nephrotic syndrome (SDNS) was approved in Japan. We herein report a woman with childhood-onset complicated SDNS due to focal and segmental glomerulosclerosis, who had two successful pregnancies while receiving RTX maintenance therapy. No adverse complications were observed during the pregnancies, and she delivered healthy newborns. This case suggested that RTX may be used safely in pregnant women complicated with SDNS. </p>
-
Comparative proteomic analysis of renal proteins from IgA nephropathy model mice and control mice
Miyakawa R.
Clinical and Experimental Nephrology ( Clinical and Experimental Nephrology ) 24 ( 8 ) 666 - 679 2020年08月