Research Achievements - Other -
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Development of a New Focal Mouse Model of Bone Metastasis in Renal Cell Carcinoma
OYA KEITA, TSUCHIE HIROYUKI, NAGASAWA HIROYUKI, HONGO MICHIO, KASUKAWA YUJI, KUDO DAISUKE, SHOJI RYO, KASAMA FUMIHITO, KAWARAGI TAKASHI, WATANABE MANABU, TOMINAGA KENTA, MIYAKOSHI NAOHISA
In Vivo ( Production services Kyorinsha Co., Ltd. ) 38 ( 3 ) 1074 - 1078 2024
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Skip Fusion With Sacral-Alar-Iliac Screw Fixation for Pelvic Ring and Lumbar Fractures: A Case Report.
Ryota Kimura, Yuji Kasukawa, Michio Hongo, Daisuke Kudo, Motoki Mita, Koji Nozaka, Naohisa Miyakoshi
Cureus 15 ( 12 ) e50022 2023.12
Pelvic ring fractures are associated with high-energy trauma and high mortality owing to critical blood loss and concomitant injuries. If there is a concurrent lumbar fracture, the postoperative range of motion will be limited owing to the increased fusion range. Here, we report a case in which skip fusion with sacral-alar-iliac screw fixation was effective as a minimally invasive procedure for treating pelvic ring and lumbar fractures.
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Epidemiology of Complete Cervical Cord Injury in Japan
Kudo Daisuke, Miyakoshi Naohisa
( The Japanese Association of Rehabilitation Medicine ) 60 ( 12 ) 1038 - 1043 2023.12
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Curve progression and risk factors in patients of adolescent idiopathic scoliosis with Risser sign grade 4
Wakabayashi Rena, Hongo Michio, Misawa Akiko, Kimura Ryota, Kudo Daisuke, Shimada Yoichi, Miyakoshi Naohisa
Journal of Spine Research ( The Japanese Society for Spine Surgery and Related Research ) 14 ( 11 ) 1377 - 1382 2023.11
<p><b>Introduction: </b>Brace treatment for adolescent idiopathic scoliosis (AIS) is usually indicated for patients with Risser sign grade 0-3, but not for above grade 4. However, we occasionally see patients whose curves progress even in patients with Risser sign grade 4. We examine Cobb angle progression and risk factors in Risser sign grade 4 cases of AIS.</p><p><b>Methods: </b>From January 2016 to December 2020, 42 AIS patients with Risser sign grade 4 at the first visit to our clinic and were followed up for at least 1 year were included. Patient background, physical findings, and radiological measurements including the Cobb angles were evaluated. Patients were divided into progressive and non-progressive groups to compare their risk factors of scoliosis.</p><p><b>Results: </b>Eight patients were in the progressive group and 34 were in the non-progressive group. In the progressive group, the Cobb angle increased by 7.1 degrees, from 28.7 to 35.8 degrees. The time since menarche was significantly shorter in the progressive group (9.7 months) than in the non-progressive group (24.2 months) (P=0.003). Growth in height was significantly greater in the progressive group (+2.9 cm) than in the non-progressive group (+1.8 cm) (P = 0.02). There were no differences in the other factors.</p><p><b>Conclusions: </b>In this study, curves progressed in approximately 20% of patients with Risser sign grade 4. In cases with short time since menarche or potential for height growth, AIS patients with Risser sign grade 4 may need to take brace therapy.</p>
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Status and issue of scoliosis screening in Akita
Misawa Akiko, Hongo Michio, Kudo Daisuke, Wakabayashi Rena, Kimura Ryota, Shimada Yoichi, Miyakoshi Naohisa
Journal of Spine Research ( The Japanese Society for Spine Surgery and Related Research ) 14 ( 11 ) 1366 - 1371 2023.11
<p><b>Introduction: </b>In Akita Prefecture, school screening using the Moiré topography have been conducted since 1984, and have been continued after the start of musculoskeletal screening. In this study, we compared the results of the scoliosis examination using the Moiré screening with those of the musculoskeletal screening using data provided by the Akita City Board of Education.</p><p><b>Methods: </b>From 2017 to 2020, 1,442 patients with spinal column findings in musculoskeletal screening and 474 patients with Moiré screening findings underwent secondary examination.</p><p><b>Results: </b>The positive predictive value for the Cobb angle of 10 degrees or more was 39% in the musculoskeletal screening, and 60% in the Moiré screening. The positive predictive value of scoliosis in junior high school students was 57% for the musculoskeletal screening, which was similar to that for the Moiré screening. 13% of the diagnosed cases were newly positive for the musculoskeletal screening and 87% were continuously positive, and most of the cases were diagnosed with scoliosis by the Moiré screening.</p><p><b>Conclusions: </b>The results of this study have once again demonstrated the usefulness of Moiré screening in comparison with musculoskeletal screening. In order to promote the use of Moiré screening, it is necessary to improve the follow-up system after the screening. In addition, it is necessary to approach and cooperate with boards of education and medical associations for the development of medical checkups to resolve issues such as the protection of personal information in order to provide feedback on the results of medical checkups.</p>
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Diagnosis and Surgical Treatment of Thoracic Dorsal Arachnoid Web: A Report of Two Cases.
Junichi Inoue, Naohisa Miyakoshi, Michio Hongo, Takashi Kobayashi, Toshiki Abe, Kazuma Kikuchi, Eiji Abe, Yuji Kasukawa, Yoshinori Ishikawa, Daisuke Kudo, Hayato Kinoshita, Ryota Kimura, Yoichi Shimada
Case reports in orthopedics 2020 8816598 - 8816598 2020
INTRODUCTION: An arachnoid web (AW) is a relatively rare disease and shows clinical symptoms and radiological findings similar to those of an arachnoid cyst (AC) or spinal cord herniation (SCH). Since the operative procedures for an AW are generally different from those intrathecal disorders, correct preoperative differential diagnosis is important. The purposes of this study were to report the usefulness of magnetic resonance imaging (MRI) and computed tomography (CT) myelography for diagnosing AW and to show the histological findings and clinical results. Case Description. Two patients, a 79-year-old man and a 43-year-old woman, are presented. The primary diagnoses were AC with ossification of the ligamentum flavum and epidural hematoma, respectively, in previous hospitals. They were finally diagnosed by the characteristic MRI and CT myelogram finding called the "scalpel sign." Histological findings showed epithelial cells and fibrous tissue derived from arachnoid tissues and microcalcifications. After surgery, the scalpel sign has vanished, and aggravation of their symptoms was prevented. CONCLUSION: An AW is refractory, but early detection by MRI and CT myelography and early treatment improve outcomes after surgery.
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Matsunaga Toshiki, Miyakoshi Naohisa, Kudo Daisuke, Saito Kimio, Kimura Ryota, Inoue Junichi, Chida Satoaki, Hatakeyama Kazutoshi, Shimada Yoichi
The Japanese Journal of Rehabilitation Medicine ( The Japanese Association of Rehabilitation Medicine ) 56 ( 7 ) 555 - 559 2019.07
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Posterior spinal fusion using a unilateral C1 posterior arch screw and a C2 laminar screw for atlantoaxial fracture dislocation.
Yuichi Ono, Naohisa Miyakoshi, Michio Hongo, Yuji Kasukawa, Yoshinori Ishikawa, Daisuke Kudo, Ryota Kimura, Jumpei Iida, Yoichi Shimada
SAGE open medical case reports 7 2050313X19849276 2019
INTRODUCTION: C1 lateral mass screws and C2 pedicle screws are usually chosen to fix atlantoaxial (C1-C2) instability. However, there are a few situations in which these screws are difficult to use, such as in a case with a fracture line at the screw insertion point and bleeding from the fracture site. A new technique using a unilateral C1 posterior arch screw and a C2 laminar screw combined with a contralateral C1 lateral mass screws-C2 pedicle screws procedure for upper cervical fixation is reported. CASE REPORT: A 24-year-old woman had an irreducible C1-C2 anterior dislocation with a type III odontoid fracture on the right side due to a traffic accident. The patient underwent open reduction and posterior C1-C2 fixation. On the left side, a C1 lateral mass screws and a C2 pedicle screws were placed. Because there was bleeding from the fracture site and a high-riding vertebral artery was seen on the right side, a C1 posterior arch screw and a C2 laminar screw were chosen. Eight months after the surgery, computed tomography scans showed healing of the odontoid fracture with anatomically correct alignment. CONCLUSIONS: Although there have been few comparable studies, fixation with unilateral C1 posterior arch screw-C2 laminar screw could be a beneficial choice for surgeries involving the upper cervical region in patients with fracture dislocation or arterial abnormalities.
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Effect of Prevalent Vertebral Fractures on Incidental Vertebral Fractures and Low Back Pain During Bisphosphonate Treatment for Osteoporosis
Yuji Kasukawa, Naohisa Miyakoshi, Toshihito Ebina, Michio Hongo, Koji Nozaka, Yoshinori Ishikawa, Hiroyuki Tsuchie, Daisuke Kudo, Yoichi Shimada
JOURNAL OF BONE AND MINERAL RESEARCH ( WILEY ) 33 175 - 175 2018.11
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Pyogenic Spondylitis Caused by Methicillin-Resistant Staphylococcus aureus Associated with Tracheostomy followed by Resection of Ossification of the Anterior Longitudinal Ligament.
Michio Hongo, Naohisa Miyakoshi, Masashi Fujii, Yuji Kasukawa, Yoshinori Ishikawa, Daisuke Kudo, Yoichi Shimada
Case reports in orthopedics 2018 9076509 - 9076509 2018
Symptomatic ossification of the anterior longitudinal ligament (OALL) is rare. However, when the osteophyte enlarges and obstructive symptoms occur, the patient may require surgery. We present a case of pyogenic spondylitis caused by methicillin-resistant Staphylococcus aureus associated with tracheostomy followed by resection of OALL. A 69-year-old woman with OALL complained of dysphagia and suffocation, which was caused by prominent OALL at C4-5. Tracheostomy was performed, followed by osteophytectomy 6 weeks later. Two months after osteophytectomy, she complained of muscle weakness of the extremities, neck pain, and elevated temperature. Magnetic resonance imaging showed an intensity change at the C4-5 vertebrae and an epidural abscess that was causing cord compression requiring urgent decompression. Cultures identified methicillin-resistant Staphylococcus aureus. As osteolytic change and muscle weakness gradually progressed, she underwent anterior and posterior reconstruction with an autograft and instrumentation. Bone union was confirmed at 1 year postoperatively with improvement in neurological status. OALL has potentially the risk of airway obstruction. Therefore, appropriate diagnosis and prompt osteophytectomy are needed in cases of a large prominent ossification that puts the patient at risk of suffocation. However, it is noted that osteophytectomy following urgent tracheostomy carries the possible risk of infection.
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Surgical Treatment for Severe Scoliosis in Patients with Reduced Cardiorespiratory Function after Surgery for Congenital Heart Disease: A Report of Two Cases.
Hayato Kinoshita, Naohisa Miyakoshi, Michio Hongo, Akiko Misawa, Daisuke Kudo, Yoichi Shimada
Case reports in orthopedics 2018 4610796 - 4610796 2018
PURPOSE: Congenital heart disease (CHD) is associated with an increased risk of scoliosis. The prognosis of scoliosis patients with CHD has improved because of advances in cardiac care. As a result, the frequency of surgery for scoliosis in this population has increased, although the risk of perioperative complications remains high. We treated two patients with CHD who underwent surgery for severe scoliosis. To avoid perioperative complications, we evaluated the preoperative cardiac status and anesthetic risks before posterior correction and fixation in both patients. METHODS: An expert anesthesiologist evaluated the anesthetic risk in each case, and an adequate reservoir of autologous blood was collected preoperatively. The patient in case 1 was at risk of significant blood loss and required extremely careful operative technique. The patient in case 2 had low cardiac output preoperatively. We therefore performed a thorough preoperative cardiac evaluation. Both patients were admitted to the intensive care unit postoperatively. RESULTS: Neither patient suffered serious complications, and both achieved favorable outcomes. CONCLUSIONS: Appropriate surgical technique and teamwork among experts are the keys to success in patients with severe scoliosis and CHD.
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Progress in Rehabilitation Medicine ( The Japanese Association of Rehabilitation Medicine ) 3 ( 0 ) n/a 2018
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Indications for Drug Holiday among Japanese Patients after Long-term Bisphosphonate Treatment.
Yuji Kasukawa, Naohisa Miyakoshi, Michio Hongo, Koji Nozaka, Yoshinori Ishikawa, Hiroyuki Tsuchie, Daisuke Kudo, Yoichi Shimada
JOURNAL OF BONE AND MINERAL RESEARCH ( WILEY ) 32 S269 - S269 2017.12
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A Review of the Current Functional Electrical Stimulation Devices
Shimada Yoichi, Matsunaga Toshiki, Kudo Daisuke, Saito Kimio
The Japanese Journal of Rehabilitation Medicine ( The Japanese Association of Rehabilitation Medicine ) 54 ( 8 ) 564 - 569 2017
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Essential Assessment and Utilizing Methods for Rehabilitation of Low Back Pain
Kudo Daisuke, Shimada Yoichi
The Japanese Journal of Rehabilitation Medicine ( The Japanese Association of Rehabilitation Medicine ) 54 ( 11 ) 835 - 840 2017