所属 |
附属病院 中央放射線部 |
学位論文 【 表示 / 非表示 】
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Safety and Treatment Outcomes of Stereotactic Body Radiotherapy for Pulmonary Tumors : A Retrospective Single-Center Study
Satoshi Kumagai, Yuki Wada, Akira Anbai, Noriko Takagi, Eriko Okuyama, Manabu Hashimoto
秋田医学 48 ( 3-4 ) 85 - 98 2022年03月 [査読有り]
国内共著
Stereotactic body radiotherapy (SBRT) uses hypofractionated and more precise irradiation methods, and has the advantages of shorter duration, better outcomes, and fewer side effects than conventional radiotherapy. However, the optimal dosage remains unclear. The purpose of the study was to analyze our preliminary treatment results and safety. We retrospectively analyzed 32 patients (primary cancer, 22; metastatic cancer, 10) who underwent SBRT for pulmonary tumors at our hospital from April 2015 to June 2020. SBRT was performed with escalated dose prescriptions (up to 55Gy in 4 fractions/64Gy in 8 fractions for peripheral/central lesions, respectively). We evaluated the local control rate (LC rate), overall survival (OS), progression-free survival (PFS), disease-specific survival (DSS), and adverse events. The target lesions comprised 22 primary lung cancers and 13 metastatic lung cancers. The 2-year LC, OS, PFS, and DSS rates were 82.5%, 68.3%, 50.5%, and 88.0% for primary lung cancer patients and 83.1%, 29.9%, 23.1%, and 48.6% for metastatic lung cancer patients, respectively. Five cases of radiation pneumonitis of grade 2 or higher, one of grade 1 dermatitis and 1 of esophagitis were observed as adverse events. We showed that the treatment outcomes of SBRT for primary and metastatic lung cancers were mostly acceptable.
研究等業績 【 表示 / 非表示 】
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Wada Y.
Cancers ( Cancers ) 13 ( 1 ) 1 - 12 2021年01月
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Sugawara M.
Japanese Journal of Radiology ( Japanese Journal of Radiology ) 37 ( 9 ) 666 - 667 2019年09月
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Wada Y.
Radiation Oncology ( Radiation Oncology ) 14 ( 1 ) 2019年06月
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Sugawara M.
Japanese Journal of Radiology ( Japanese Journal of Radiology ) 37 ( 3 ) 220 - 229 2019年03月