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所属 |
附属病院 第二内科 |
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生年 |
1986年 |
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研究室住所 |
秋田市広面字蓮沼44-2 |
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研究室電話 |
018-884-6110 |
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メールアドレス |
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岩川 英弘 (イワカワ ヒデヒロ)
IWAKAWA Hidehiro
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研究等業績 【 表示 ／ 非表示 】
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Yamaguchi J.
PACE - Pacing and Clinical Electrophysiology ( PACE - Pacing and Clinical Electrophysiology ) 46 ( 12 ) 1536 - 1545 2023年12月
研究論文（学術雑誌）
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Iwakawa H.
Journal of Arrhythmia ( Journal of Arrhythmia ) 39 ( 5 ) 813 - 815 2023年10月
研究論文（学術雑誌）
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Kaimori R.
Journal of Electrocardiology ( Journal of Electrocardiology ) 80 63 - 68 2023年09月
研究論文（学術雑誌）
BACKGROUND: Advanced interatrial block (A-IAB) on electrocardiography (ECG) represents the conduction delay between the left and right atria. We investigated the association of A-IAB with left and right atrial (LA/RA) remodeling in patients with atrial fibrillation (AF). METHODS: We enrolled 74 patients who underwent ECG, cardiac computed tomography (CCT), and echocardiography during sinus rhythm before catheter ablation of AF. A-IAB was defined as P-wave duration ≥120 ms with a biphasic morphology in leads III and aVF or notched morphology in lead II. We compared the maximum and minimum LA/RA volume indices (max and min LAV/RAVI), LA/RA expansion index (LAEI/RAEI), and total, passive, and active LA/RA emptying fraction (LAEF/RAEF) between patients with and without A-IAB. RESULTS: Of the 74 patients (mean age, 64.3 ± 9.6 years), 35 (47%) showed A-IAB. Patients with A-IAB had a significantly higher likelihood of hypertension and left ventricular diastolic dysfunction than those without. Patients with A-IAB had significantly larger max (69.2 [60.7-79.7]mL/m2 vs. 60.9 [50.4-68.3]mL/m2, P < 0.01) and min (44.0 [37.2-52.1]mL/m2 vs. 34.1 [29.2-43.5]mL/m2, P < 0.01) LAVI than those without. The max and min RAVI were not significantly different between groups. LAEI (55.1 [48.2-78.5]% vs. 72.1 [57.8-84.8]%, P < 0.05), total LAEF (35.5 [32.5-44.0]% vs. 41.9 [36.6-45.9]%, P < 0.05), and passive LAEF (12.2 [10.0-14.4]% vs. 15.5 [11.2-19.6]%, P < 0.05) were significantly lower in patients with A-IAB than without. CONCLUSIONS: A-IAB was associated with LA, but not RA enlargement, in patients with AF. A-IAB may indicate LA functional remodeling in the reservoir and conduit phases.
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Nagashima K.
Journal of Arrhythmia ( Journal of Arrhythmia ) 40 ( 1 ) 131 - 142 2023年
研究論文（学術雑誌）
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Utility of P-wave abnormalities for distinguishing embolic stroke from non-embolic stroke
Iwakawa H.
International Journal of Cardiology ( International Journal of Cardiology ) 368 72 - 77 2022年12月 [査読有り]
研究論文（学術雑誌）
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Iwakawa H.
Circulation Journal ( Circulation Journal ) 87 ( 12 ) 1757 - 1764 2023年
<p><b><i>Background:</i></b> For lesion size prediction, each input parameter, including ablation energy (AE), and output parameter, such as impedance, is individually used. We hypothesize that using both parameters simultaneously may be more optimal.</p><p><b><i>Methods and Results:</i></b> Radiofrequency applications at a range of power (30–50 W), contact force (10 g and 20 g), duration (10–60 s), and catheter orientation with normal saline (NS)- or half-normal saline (HNS)-irrigation were performed in excised porcine hearts. The correlations, with lesion size of AE, absolute impedance drop (∆Imp-drop), relative impedance drop (%Imp-drop), and AE*%Imp-drop were examined. Lesion size was analyzed in 283 of 288 lesions (NS-irrigation, n=142; HNS-irrigation, n=141) without steam pops. AE*%Imp-drop consistently showed the strongest correlations with lesion maximum depth (NS-irrigation, ρ=0.91; HNS-irrigation, ρ=0.94), surface area (NS-irrigation, ρ=0.87; HNS-irrigation, ρ=0.86), and volume (NS-irrigation, ρ=0.94; HNS-irrigation, ρ=0.94) compared with the other parameters. Moreover, compared with AE alone, AE*%Imp-drop significantly improved the strength of correlation with lesion maximum depth (AE vs. AE*%Imp-drop, ρ=0.83 vs. 0.91, P<0.01), surface area (ρ=0.73 vs. 0.87, P<0.01), and volume (ρ=0.84 vs. 0.94, P<0.01) with NS-irrigation. This tendency was also observed with HNS-irrigation. Parallel catheter orientation showed a better correlation with lesion depth and volume using ∆Imp-drop, %Imp-drop, and AE*%Imp-drop than perpendicular orientation.</p><p><b><i>Conclusions:</i></b> The combination of input and output parameters is more optimal than each single parameter for lesion prediction.</p>