Research Achievements - Original paper -

Effects of CYP3A4/5 and ABC transporter polymorphisms on osimertinib plasma concentrations in Japanese patients with non-small cell lung cancer

Hayato Yokota, Kazuhiro Sato, Sho Sakamoto, Yuji Okuda, Natsuki Fukuda, Mariko Asano, Masahide Takeda, Katsutoshi Nakayama, Masatomo Miura

Investigational New Drugs ( Investigational New Drugs )  40 ( 6 ) 1254 - 1262   2022.12  [Refereed]

Research paper (journal)  

DOI CiNii Research

Improving performance and self-efficacy of novice nurses using hybrid simulation-based mastery learning

Rinko Takashiki, Junko Komatsu, Mari Nowicki, Yuki Moritoki, Mieko Okazaki, Shigetoshi Ohshima, Hitoshi Hasegawa, Kyoko Nomura, Gen Ouchi, Benjamin W Berg, Hideko Shirakawa, Katsutoshi Nakayama, Naoto Takahashi.

Japan Journal of Nursing Science ( Japan Journal of Nursing Science )  20 ( 2 )   2022.11  [Refereed]

Research paper (journal)  

DOI

Eosinophil extracellular traps in a patient with chronic eosinophilic pneumonia

Masahide Takeda, Sho Sakamoto, Shigeharu Ueki, Yui Miyabe, Mineyo Fukuchi, Yuji Okuda, Mariko Asano, Kazuhiro Sato, Katsutoshi Nakayama.

Asia Pacific Allergy ( Asia Pacific Allergy )  11   2021.07  [Refereed]

Research paper (journal)  

DOI

Impaired TRIM16-Mediated Lysophagy in Chronic Obstructive Pulmonary Disease Pathogenesis

Jun Araya, Nayuta Saito, Yusuke Hosaka, Akihiro Ichikawa, Tsukasa Kadota, Yu Fujita, Shunsuke Minagawa, Hiromichi Hara, Shota Fujimoto, Hironori Kawamoto, Naoaki Watanabe, Akihiko Ito, Keitaro Okuda, Hanae Miyagawa, Junko Watanabe, Daisuke Takekoshi, Hirofumi Utsumi, Masahiro Yoshida, Mitsuo Hashimoto, Hiroshi Wakui, Saburo Ito, Takanori Numata, Shohei Mori, Hideki Matsudaira Jun Hirano, Takashi Ohtsuka, Katsutoshi Nakayama, Kazuyoshi Kuwano

J Immunol ( Journal of Immunology )  207 ( 1 ) 65 - 76   2021.07  [Refereed]

Research paper (journal)   Single author

DOI

Unusual morphologies of blood eosinophils in GM-CSF-producing lung cancer

Izumiya Y, Okuda Y, Ueki S, Takeda M, Sato K, Nakayama K.

QJM : monthly journal of the Association of Physicians ( QJM : monthly journal of the Association of Physicians )  114 ( 1 ) 42 - 44   2021.02

Research paper (journal)  

DOI

ABCG2 C421A polymorphisms affect exposure of the epidermal growth factor receptor inhibitor gefitinib

Sakamoto Sho, Sato Kazuhiro, Takita Yuri, Izumiya Yuka, Kumagai Naho, Sudo Kazuhisa, Hasegawa Yukiyasu, Yokota Hayato, Akamine Yumiko, Okuda Yuji, Asano Mariko, Takeda Masahide, Sano Masaaki, Miura Masatomo, Nakayama Katsutoshi.

Investigational New Drugs ( Investigational New Drugs )  38 ( 6 ) 1687 - 1695   2020.12  [Refereed]

Research paper (journal)  

DOI

Clinical benefits of adjuvant chemotherapy with carboplatin and gemcitabine in patients with non-small cell lung cancer: A single-center retrospective study

Takashima Shinogu, Imai Kazuhiro, Atari Maiko, Matsuo Tsubasa, Nakayama Katsutoshi, Sato Yusuke, Motoyama Satoru, Shibata Hiroyuki, Nomura Kyoko, Minamiya Yoshihiro.

World Journal of Surgical Oncology ( World Journal of Surgical Oncology )  18 ( 1 )   2020.10

Research paper (journal)  

DOI

Chaperone-mediated autophagy suppresses apoptosis via regulation of the unfolded protein response during chronic obstructive pulmonary disease pathogenesis

Hosaka Yusuke, Araya Juna, Fujita Yu, Kadota Tsukasa, Tsubouchi Kazuya, Yoshida Masahiro, Minagawa Shunsuke, Hara Hiromichi, Kawamoto Hironori, Watanabe Naoaki, Ito Akihiko, Ichikawa Akihiro, Saito Nayuta, Okuda Keitaro, Watanabe Junko, Takekoshi Daisuke, Utsumi Hirofumi, Hashimoto Mitsuo, Wakui Hiroshi, Ito Saburo, Numata Takanori, Mori Shohei, Matsudaira Hideki, Hirano Jun, Ohtsuka Takashi, Nakayama Katsutoshi, Kuwano Kazuyoshi.

Journal of Immunology ( Journal of Immunology )  205 ( 5 ) 1256 - 1267   2020.09  [Refereed]

Research paper (journal)  

DOI

Effects of STAT3 polymorphisms and pharmacokinetics on the clinical outcomes of gefitinib treatment in patients with EGFR-mutation positive non-small cell lung cancer

Yokota Hayato, Sato Kazuhiro, Sakamoto Sho, Okuda Yuji, Asano Mariko, Takeda Masahide, Nakayama Katsutoshi, Miura Masatomo

Journal of Clinical Pharmacy and Therapeutics ( Journal of Clinical Pharmacy and Therapeutics )  45 ( 4 ) 652 - 659   2020.08  [Refereed]

Research paper (journal)  

DOI

Hypereosinophilic syndrome with abundant Charcot-Leyden crystals in spleen and lymph nodes

Masahide Takeda, Shigeharu Ueki, Yohei Yamamoto, Miho Nara, Mineyo Fukuchi 2, Katsutoshi Nakayama, Yasufumi Omori, Naoto Takahashi, Makoto Hirokawa

Asia Pac Allergy   10 ( 3 ) e24   2020.07  [Refereed]

Research paper (journal)   Domestic Co-author

DOI

Pleural fluid eosinophilia: A possible adverse event of interleukin-17 inhibition

Hayashi Wakiko, Osada Shin-Ichi, Toyoshima Aya, Yamada Katsuhiro, Sudo Kazuhisa, Nakayama Katsutoshi, Manabe Motomu.

Acta Dermato-Venereologica ( Acta Dermato-Venereologica )  99 ( 12 ) 1174 - 1175   2019.11  [Refereed]

Research paper (journal)  

DOI

Efficacy of mepolizumab for patients with severe asthma and eosinophilic chronic rhinosinusitis.

Numata T, Nakayama K, Utsumi H, Kobayashi K, Yanagisawa H, Hashimoto M, Minagawa S, Ishikawa T, Hara H, Araya J, Kuwano K.

BMC Pulm Med     2019.10  [Refereed]

Research paper (journal)   Domestic Co-author

Involvement of GPx4-Regulated Lipid Peroxidation in Idiopathic Pulmonary Fibrosis Pathogenesis.

Tsubouchi K, Araya J, Yoshida M, Sakamoto T, Koumura T, Minagawa S, Hara H, Hosaka Y, Ichikawa A, Saito N, Kadota T, Kurita Y, Kobayashi K, Ito S, Fujita Y, Utsumi H, Hashimoto M, Wakui H, Numata T, Kaneko Y, Mori S, Asano H, Matsudaira H, Ohtsuka T, Nakayama K, Nakanishi Y, Imai H, Kuwano K.

J Immunol     2019.10  [Refereed]

Research paper (journal)   Domestic Co-author

Phase II trial of induction chemotherapy with carboplatin and paclitaxel plus bevacizumab in patients with stage IIIA to IV nonsquamous non-small cell lung cancer

Imai K, Nakagawa T, Matsuzaki I, Orino K, Saito H, Sato K, Sano M, Nakayama K, Sato Y, Motoyama S, Nomura K, Shibata H, Minamiya Y.

Surgery Today ( Surgery Today )  49 ( 8 ) 678 - 685   2019.08  [Refereed]

Research paper (journal)  

DOI

Blepharoptosis due to Sarcoidosis-induced Horner Syndrome.

Takeda M, Sato K, Sano M, Sakamoto S, Izumiya Y, Kumagai N, Sudo K, Asano M, Okuda Y, Nakayama K.

Am J Respir Crit Care Med     2019.07  [Refereed]

Research paper (journal)  

Involvement of cigarette smoke-induced epithelial cell ferroptosis in COPD pathogenesis.

Yoshida M, Minagawa S, Araya J, Sakamoto T, Hara H, Tsubouchi K, Hosaka Y, Ichikawa A, Saito N, Kadota T, Sato N, Kurita Y, Kobayashi K, Ito S, Utsumi H, Wakui H, Numata T, Kaneko Y, Mori S, Asano H, Yamashita M, Odaka M, Morikawa T, Nakayama K, Iwamoto T, Imai H, Kuwano K.

Nat Commun     2019.07  [Refereed]

Research paper (journal)   Domestic Co-author

An autopsy case of anaplastic lymphoma kinase-positive lung cancer exacerbated in a short period of time: A case report

Takeda M, Sato K, Sakamoto S, Suzuki M, Izumiya Y, Kumagai N, Sudo K, Okuda Y, Asano M, Sano M, Omori Y, Nakayama K.

Journal of Medical Case Reports ( Journal of Medical Case Reports )  13 ( 1 )   2019.04  [Refereed]

Research paper (journal)  

DOI

Involvement of Lamin B1 Reduction in Accelerated Cellular Senescence during Chronic Obstructive Pulmonary Disease Pathogenesis.

Saito N, Araya J, Ito S, Tsubouchi K, Minagawa S, Hara H, Ito A, Nakano T, Hosaka Y, Ichikawa A, Kadota T, Yoshida M, Fujita Y, Utsumi H, Kurita Y, Kobayashi K, Hashimoto M, Wakui H, Numata T, Kaneko Y, Asano H, Odaka M, Ohtsuka T, Morikawa T, Nakayama K, Kuwano K.

J Immunol     2019.03  [Refereed]

Research paper (journal)   Domestic Co-author

PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis.

Araya J, Tsubouchi K, Sato N, Ito S, Minagawa S, Hara H, Hosaka Y, Ichikawa A, Saito N, Kadota T, Yoshida M, Fujita Y, Utsumi H, Kobayashi K, Yanagisawa H, Hashimoto M, Wakui H, Ishikawa T, Numata T, Kaneko Y, Asano H, Yamashita M, Odaka M, Morikawa T, Nishimura SL, Nakayama K, Kuwano K.

Autophagy     2019.03  [Refereed]

Research paper (journal)   Domestic Co-author

Aortic rupture involving matrix metalloproteinases 8 and 9 during Staphylococcus aureus pneumonia.

Hashimoto M, Kuriiwa S, Kojima A, Minagawa S, Numata T, Hara H, Araya J, Kaneko Y, Nakayama K, Owada M, Aizawa D, Yorozu T, Suzuki M, Kuwano K.

Thorax.     2018.04  [Refereed]

Research paper (journal)   Domestic Co-author

Risk factors of postoperative pulmonary complications in patients with asthma and COPD.

Numata T, Nakayama K, Fujii S, Yumino Y, Saito N, Yoshida M, Kurita Y, Kobayashi K, Ito S, Utsumi H, Yanagisawa H, Hashimoto M, Wakui H, Minagawa S, Ishikawa T, Hara H, Araya J, Kaneko Y, Kuwano K.

BMC Pulm Med.     2018.01  [Refereed]

Research paper (journal)   Domestic Co-author

Detection of pathogens by real-time PCR in adult patients with acute exacerbation of bronchial asthma.

Yoshii Y, Shimizu K, Morozumi M, Chiba N, Ubukata K, Uruga H, Hanada S, Wakui H, Minagawa S, Hara H, Numata T, Saito K, Araya J, Nakayama K, Kishi K, Kuwano K.

BMC Pulm Med.     2017.11  [Refereed]

Research paper (journal)   Domestic Co-author

Macroscopic inflammatory tracheal and endobronchial nodules in Sjögren's syndrome.

Hara H, Kuwano K, Minagawa S, Numata T, Araya J, Nakayama K.

Thorax.     2017.09  [Refereed]

Research paper (journal)   Domestic Co-author

Azithromycin attenuates myofibroblast differentiation and lung fibrosis development through proteasomal degradation of NOX4.

Tsubouchi K, Araya J, Minagawa S, Hara H, Ichikawa A, Saito N, Kadota T, Sato N, Yoshida M, Kurita Y, Kobayashi K, Ito S, Fujita Y, Utsumi H, Yanagisawa H, Hashimoto M, Wakui H, Yoshii Y, Ishikawa T, Numata T, Kaneko Y, Asano H, Yamashita M, Odaka M, Morikawa T, Nakayama K, Nakanishi Y, Kuwano K.

Autophagy     2017.08  [Refereed]

Research paper (journal)   Domestic Co-author

Pirfenidone inhibits myofibroblast differentiation and lung fibrosis development during insufficient mitophagy.

Kurita Y, Araya J, Minagawa S, Hara H, Ichikawa A, Saito N, Kadota T, Tsubouchi K, Sato N, Yoshida M, Kobayashi K, Ito S, Fujita Y, Utsumi H, Yanagisawa H, Hashimoto M, Wakui H, Yoshii Y, Ishikawa T, Numata T, Kaneko Y, Asano H, Yamashita M, Odaka M, Morikawa T, Nakayama K, Kuwano K.

Respir Res.     2017.06  [Refereed]

Research paper (journal)   Domestic Co-author

Mild lung tuberculosis in a patient suffering from status epilepticus caused by the syndrome of inappropriate secretion of antidiuretic hormone (SIADH).

Hashimoto M, Kuriiwa S, Kojima A, Shinhuku K, Sato A, Sasaki R, Hasegawa T, Ito A, Utsumi H, Yanagisawa H, Wakui H, Minagawa S, Kojima J, Numata T, Hara H, Araya J, Kaneko Y, Nakayama K, Kuwano K.

Intern Med.     2017.02  [Refereed]

Research paper (journal)   Domestic Co-author

Increased levels of prostaglandin E-major urinary metabolite (PGE-MUM) in chronic fibrosing interstitial pneumonia.

Horikiri T, Hara H, Saito N, Araya J, Takasaka N, Utsumi H, Yanagisawa H, Hashimoto M, Yoshii Y, Wakui H, Minagawa S, Ishikawa T, Shimizu K, Numata T, Arihiro S, Kaneko Y, Nakayama K, Matsuura T, Matsuura M, Fujiwara M, Okayasu I, Ito S, Kuwano K.

Respir Med.     2017.01  [Refereed]

Research paper (journal)   Domestic Co-author