Research Achievements - Original paper -

Dietary nitrate generates potentially mutagenic concentrations of nitric oxide at the gastroesophageal junction.

Iijima K, Henry E, Moriya A, Wirz A, Kelman AW, McColl KE.

Gastroenterology     2002.01  [Refereed]

Research paper (journal)   Domestic Co-author

Changes in gastric acid secretion assayed by endoscopic gastrin test before and after Helicobacter pylori eradication.

Iijima K, Ohara S, Sekine H, Koike T, Kato K, Asaki S, Shimosegawa T, Toyota T.

Gut     2000.01

Research paper (journal)   Domestic Co-author

A new endoscopic method of gastric acid secretory testing.

Iijima K, Ohara S, Sekine H, Koike T, Kubota Y, Kato K, Asaki S, Toyota T.

Am J Gastroenterol.     1999.11  [Refereed]

Research paper (journal)   Domestic Co-author

Gender differences in esophageal mucosal injury in a reflux esophagitis model of rats.

Masaka T, Iijima K, Endo H, Asanuma K, Ara N, Ishiyama F, Asano N, Koike T, Imatani A, Shimosegawa T.

Gut     2013.01  [Refereed]

Research paper (journal)   Domestic Co-author

Diffusion of cytotoxic concentrations of nitric oxide generated luminally at the gatro-esophageal junction of rats

25. Asanuma K, Iijima K, Sugata H, Ohara S, Shimosegawa T, Yoshimura T.

Gut     2005.01  [Refereed]

Research paper (journal)   Domestic Co-author

Time series analysis of gastric acid secretion over a 20-year period in normal Japanese men.

Iijima K, Koike T, Abe Y, Ohara S, Nakaya N, Shimosegawa T.

J Gastroenterol.     2015.08  [Refereed]

Research paper (journal)   Domestic Co-author

Peptic ulcers after the Great East Japan earthquake and tsunami: possible existence of psychosocial stress ulcers in humans.

Kanno T, Iijima K, Abe Y, Koike T, Shimada N, Hoshi T, Sano N, Ohyauchi M, Ito H, Atsumi T, Konishi H, Asonuma S, Shimosegawa T.

J Gastroenterol.     2013.04  [Refereed]

Research paper (journal)   Domestic Co-author

Involvement of luminal nitric oxide in the pathogenesis of the gastro-esophageal reflux disease spectrum (review).

Iijima K, Shimosegawa T.

J Gastroenterol Hepatol.     2014.05  [Refereed]  [Invited]

Research paper (journal)   Domestic Co-author

Is the new potent acid-inhibitory drug vonoprazan effective for healing idiopathic peptic ulcers? A multicenter observational study in Akita Prefecture, Japan.

Sugawara K, Koizumi S, Horikawa Y, Mimori N, Tsuji T, Ishii H, Fujimori S, Onochi K, Watanabe H, Iijima K.

J Gastroenterol.     2019.11  [Refereed]

Research paper (journal)   Domestic Co-author

Is the incidence of esophageal adenocarcinoma increasing in Japan? Trends from the data of a hospital-based registration system in Akita Prefecture, Japan.

Koizumi S, Motoyama S, Iijima K.

J Gastroenterol.     2018.07  [Refereed]

Research paper (journal)   Domestic Co-author

Identification of a high-risk group for low-dose aspirin-induced gastropathy by measuring serum pepsinogen in H. pylori-infected subjects.

Iijima K, Koike T, Ara N, Nakagawa K, Kondo Y, Uno K, Hatta W, Asano N, Imatani A, Shimosegawa T.

J Gastroenterol.     2015.03  [Refereed]

Research paper (journal)   Domestic Co-author

Direct Measurement of Gastroesophageal Reflux Episodes in Patients With Squamous Cell Carcinoma by 24-h pH-Impedance Monitoring.

70. Uno K, Iijima K, Hatta W, Koike T, Abe Y, Asano N, Kusaka G, Shimosegawa T.

Am J Gastroenterol     2011.11  [Refereed]

Research paper (journal)   Domestic Co-author

Gastric acid secretion level modulates the association between Helicobacter pylori infection and low-dose aspirin-induced gastropathy.

Iijima K, Ara N, Abe Y, Koike T, Iwai W, Uno K, Asano N, Imatani A, Ohara S, Shimosegawa T.

J Gastroenterol.     2011.05  [Refereed]

Research paper (journal)   Domestic Co-author

Sustained epithelial proliferation in a functionally irreversible fundic mucosa after H. pylori eradication.

Iijima K, Koike T, Sekine H, Abe Y, Asanuma K, Ara N, Uno K, Imatani A, Ohara S, Shimosegawa T.

J Gastroenterol     2009.01  [Refereed]

Research paper (journal)   Domestic Co-author

Disruption of gastric barrier function by luminal nitrosative stress: a potential chemical insult to the human gastro-oesophageal junction.

Ara N, Iijima K, Asanuma K, Yoshitake J, Ohara S, Shimosegawa T, Yoshimura T.

Gut     2008.03  [Refereed]

Research paper (journal)   Domestic Co-author

Extensive gastric atrophy: an increased risk factor for superficial esophageal squamous-cell carcinoma in Japan.

Iijima K, Koike T, Abe Y, Inomata Y, Sekine H, Imatani A, Nakaya N, Ohara S, Shimosegawa T.

Am J Gastroenterol     2007.08  [Refereed]

Research paper (journal)   Domestic Co-author

Long-term effect of Helicobacter pylori eradication on the reversibility of acid secretion in profound hypochlorhydria.

Iijima K, Sekine H, Koike T, Imatani A, Ohara S, Shimosegawa T.

Aliment Pharmacol Ther     2004.01  [Refereed]

Research paper (journal)   Domestic Co-author

Novel mechanism of nitrosative stress from dietary nitrate with relevance to gastroesophageal junction cancers.

Iijima K, Grant J, McElroy K, Fyfe V, Preston T, McColl KE.

carcinogenesis     2003.01  [Refereed]

Research paper (journal)   Domestic Co-author