研究等業績 - その他 - 廣嶋　優子

Evaluation of Grading Estrogen Receptors in Breast Cancer Using Fully Automated Rapid Immunohistochemistry Based on Alternating-Current Electric Field Technology

Kudo C.

Cancers ( Cancers )  17 ( 3 )   2025年02月

DOI

嵌頓をきたした十二指腸のBrunner腺過形成を内視鏡的に切除しえた１例（動画付き）

佐藤 真生, 吉田 樹, 松橋 保, 高橋 壮, 福田 翔, 南條 博, 廣嶋 優子, 飯島 克則

日本消化器内視鏡学会雑誌 ( 一般社団法人 日本消化器内視鏡学会 )  67 ( 2 ) 140 - 148   2025年

<p>十二指腸球部に60mm大の有茎性の粘膜下病変を認められた．Brunner腺過形成が疑われたが，病変の大きさから切除を検討された．しかし，本人に切除の希望がなかったため，経過観察をされた．診断から11年後，心窩部痛をきたし，CTで同病変の十二指腸水平部への嵌頓を認めた．そこで，病変をESDで切除した上で，開腹で切除検体を回収した．最終的に75mm大のBrunner腺過形成と診断された．Brunner腺過形成は，十二指腸の粘膜下病変として発見されることが多いが，確定診断は容易ではない．したがって，増大傾向がある場合や通過障害の原因となる場合には，腫瘍との鑑別のためにも切除の対象となることがある．今回，経過観察中に増大し，嵌頓をきたした十二指腸Brunner腺過形成を内視鏡的に切除しえたが，病変の体外への回収には開腹手術を要した症例を経験した．</p>

DOI CiNii Research

特集1 動脈解離再考! 今こそ全身の動脈解離を網羅する 動脈解離の病理所見

畠山 遥, 廣嶋 優子, 南條 博

臨床画像 ( メジカルビュー社 )  40 ( 9 ) 1046 - 1053   2024年09月

DOI CiNii Research

Detailed molecular and pathological analyses of primary intracranial embryonal rhabdomyosarcoma with a BRAF mutation: illustrative case

Abe M.

Journal of Neurosurgery: Case Lessons ( Journal of Neurosurgery: Case Lessons )  6 ( 1 )   2023年

DOI

Remission of idiopathic retroperitoneal fibrosis by ofatumumab as a disease-modifying therapy for multiple sclerosis

Hanazono A.

eNeurologicalSci ( eNeurologicalSci )  29   2022年12月

DOI

Changes in Serum Trace Element Concentrations before and after Surgery in Resectable Breast Cancer

Takahashi E.

Anticancer Research ( Anticancer Research )  42 ( 11 ) 5323 - 5334   2022年11月

DOI

Rapid intraoperative Ki-67 immunohistochemistry for lung cancer using non-contact alternating current electric field mixing

Atari M.

Lung Cancer ( Lung Cancer )  173   75 - 82   2022年11月

DOI

A CASE OF RENAL ANASTOMOSING HEMANGIOMA

Sasaki Y.

Acta Urologica Japonica ( Acta Urologica Japonica )  68 ( 8 ) 265 - 269   2022年08月

A 65-year-old man was found to have a 1.7 cm right renal mass by follow-up abdominal computed tomography for left total nephrectomy after a traffic accident. The renal mass progressed slowly to 2.2 cm in three years and enhanced magnetic resonance imaging revealed marked T2 weighting hyperintensity of the lesion. Although a radiologist (TK) suggested the diagnosis renal anastomosing hemangioma preoperatively, we could not deny the possibility of renal cell carcinoma completely. Therefore, the patient underwent robot-assisted laparoscopic partial nephrectomy. The tumor was successfully removed without any renal arterial clamping or parenchymal excision. Histopathologically, the lesion was composed of capillary-size blood vessels lined by a single layer of endothelial cells, and was diagnosed as a renal anastomosing hemangioma. There were no signs of postoperative recurrence during the 3 month follow-up.

DOI CiNii Research

Intraoperative rapid immunohistochemistry with noncontact antibody mixing for undiagnosed pulmonary tumors

Imai K.

Cancer Science ( Cancer Science )  114 ( 2 ) 702 - 711   2022年

DOI

Harmonization across programmed death ligand 1 (PD-L1) assays for lung cancer by immunohistochemistry using noncontact alternating current electric field mixing

Matsuo T.

Thoracic Cancer ( Thoracic Cancer )  12 ( 8 ) 1187 - 1194   2021年04月

DOI

Stapler-lavage cytology using a new rapid immunocytochemistry for evaluating surgical margin status after pulmonary sublobar resection

Kurihara N.

General Thoracic and Cardiovascular Surgery ( General Thoracic and Cardiovascular Surgery )  70 ( 4 ) 359 - 365   2021年

DOI

Intraoperative diagnosis of lymph node metastasis during segmentectomy for non-small cell lung cancer by rapid immunohistochemistry using noncontact alternating current electric field mixing

Imai K.

Thoracic Cancer ( Thoracic Cancer )  11 ( 12 ) 3547 - 3554   2020年12月

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Impact of nuclear YAP1 expression in residual cancer after neoadjuvant chemohormonal therapy with docetaxel for high-risk localized prostate cancer

Matsuda Y.

BMC Cancer ( BMC Cancer )  20 ( 1 )   2020年04月

DOI

Two autopsy cases of desmoplastic small round cell tumor

Yamamoto Y.

Pathology International ( Pathology International )  70 ( 3 ) 171 - 178   2020年03月

DOI

Aggressive inflammatory myofibroblastic tumor without anaplastic lymphoma kinase gene rearrangement in the rectum with liver metastasis

Shimodaira Y.

Internal Medicine ( Internal Medicine )  59 ( 4 ) 495 - 499   2020年02月

<p>Inflammatory myofibroblastic tumor is a rare intermediate-grade tumor. We herein report the case of an 81-year-old man with rectal ulceration and abnormal retroperitoneal soft tissue with a high serum level of IgG4. The administration of prednisolone reduced the retroperitoneal lesion; however, the rectal ulceration expanded. Surgical resection was performed. A histopathological examination revealed proliferating spindle cells accompanied by inflammatory cells and plasma cells. Liver metastasis emerged two months after surgical resection, and the histology of the proliferating spindle cells sampled by a fine-needle biopsy was similar to that of the rectal tissue. The patient ultimately died of inflammatory myofibroblastic tumor. </p>

DOI PubMed CiNii Research

Alopecia universalis successfully treated with kenchuto groups in a pediatric patient

Irie Y.

Traditional and Kampo Medicine ( Traditional and Kampo Medicine )  6 ( 3 ) 178 - 181   2019年12月

DOI

Efficacy and safety of tyrosine kinase inhibitors for newly diagnosed chronic-phase chronic myeloid leukemia over a 5-year period: results from the Japanese registry obtained by the New TARGET system

Kizaki M.

International Journal of Hematology ( International Journal of Hematology )  109 ( 4 ) 426 - 439   2019年04月

DOI

手術中に病気を視る迅速免疫染色入門

南條 博, 赤上 陽一, 中村 竜太, 廣嶋 優子, 寺田 かおり, 今井 一博, 南谷 佳弘

年次大会 ( 一般社団法人 日本機械学会 )  2019 ( 0 )   2019年

<p>Immunohistochemistry (IHC) is the most common application of immunostaining. It is widely used in the disgnosis of abnormal cells such as those found in cancerous tumors. Intraoperative pathological diagnosis is also important in selecting suitable surgery for cancer patients. We performed intraoperative diagnosis of 830 cases in Akita University Hospital., with a novel method of rapid-immunohistochemistory (R-IHC) using an alternating current electric field. The results were very good, R-IHC detected an objective evidence that were undetected using conventional HE staining. So we can diagnose degree of malignancy, histological type of cancer, and lymph node metastasis more accurately.</p>

DOI

手術中に病気を視る迅速免疫染色入門

南條 博, 赤上 陽一, 中村 竜太, 廣嶋 優子, 寺田 かおり, 今井 一博, 南谷 佳弘

年次大会 ( 一般社団法人 日本機械学会 )  2019 ( 0 ) W02101   2019年

DOI CiNii Research

Kampo Medicines for Frailty in Locomotor Disease

Nakae H.

Frontiers in Nutrition ( Frontiers in Nutrition )  5   2018年04月

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