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Affiliation |
Hospital Neurosurgery |
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Laboratory Address |
1-1-1 Hondo Akita-city AKITA, JAPAN |
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Laboratory Phone number |
+81-18-884-6140 |
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Laboratory Fax number |
+81-18-836-2616 |
TAKAHASHI Yusuke
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Graduating School 【 display / non-display 】
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-2007.03
Akita University Faculty of Medicine Graduated
Graduate School 【 display / non-display 】
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-2013.03
Akita University Graduate School, Division of Medicine Doctor's Course Completed
Campus Career 【 display / non-display 】
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2024.04-Now
Akita University Graduate School of Medicine Doctorial Course in Medicine Organ Function-Oriented Medicine Department of Neurosurgery Lecturer
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2020.04-2023.04
Akita University Graduate School of Medicine Doctorial Course in Medicine Organ Function-Oriented Medicine Assistant Professor
Thesis for a degree 【 display / non-display 】
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REMARKABLE INCREASE OF CYTOCHROME C OXIDASE SUBUNIT I AFTER GLOBAL CEREBRAL ISCHEMIA
Yusuke Takahashi, Taku Sugawara, Toshio Miyazaki, Hideaki Itoh, Kazuo Shimizu
秋田医学 39 ( 2 ) 53 - 59 2013.03
Domestic Co-author
Research Achievements 【 display / non-display 】
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Takahashi Yusuke, Suda Yoshitaka, Fushimi Susumu, Shibata Kenichi, Kondo Rui, Oda Masaya, Shimizu Hiroaki
脳神経血管内治療 ( 特定非営利活動法人 日本脳神経血管内治療学会 ) 14 ( 7 ) 273 - 278 2020 [Refereed]
Research paper (journal) Single author
<p><b>Objective:</b> Surgical removal of meningiomas that have partially invaded the superior sagittal sinus (SSS) is difficult because it requires reconstruction of the SSS, which can lead to SSS occlusion and venous infarction. The present report details the case of an SSS-involved meningioma treated by stereotactic radiosurgery (SRS) and stenting.</p><p><b>Case Presentation:</b> A 60-year-old woman was admitted to the hospital with blurred vision and papilledema. Lumbar puncture showed markedly increased intracranial pressure (ICP; 340 mm H2O). Gadolinium-enhanced T1-weighted imaging revealed a 1-cm meningioma located mainly in the SSS. Digital subtraction angiography revealed severe stenosis, at the posterior part of the SSS, and no collateral flow. The ICP was considered a result of the stenosis caused by the meningioma. A combined therapy comprising transarterial embolization (for tumor growth suppression), endovascular stenting of the SSS (for intracranial hypertension improvement), and SRS (for tumor control) was planned. SRS was performed first to avoid interference by the metal artifacts caused by the stent. After placement of a self-expanding stent, partial recanalization was achieved. Two months after stenting, SSS stenosis improved and MRI results showed shrinkage of the meningioma. Thirty months after the treatment, no tumor recurrence was observed.</p><p><b>Conclusion:</b> The treatment strategy of SRS followed by stenting was successful for a SSS-involved meningioma. ICP and a pressure gradient between the pre- and post-stenotic segments should be considered indications for stenting.</p>
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Rapid <i>de novo</i> Formation of a Large Aneurysm in a Patient with Fibromuscular Dysplasia
Suda Yoshitaka, Kokubun Kouhei, Takahashi Yusuke, Saito Ayana, Wakasa Ryosei, Shimizu Hiroaki
脳神経血管内治療 ( 特定非営利活動法人 日本脳神経血管内治療学会 ) 14 ( 2 ) 69 - 75 2020 [Refereed]
Research paper (journal) Domestic Co-author
<p><b>Objective:</b> The authors report the first case of intracranial fibromuscular dysplasia (FMD) presenting with rapid <i>de novo</i> formation of an unruptured large vertebral artery (VA) fusiform aneurysm.</p><p><b>Case Presentation:</b> A 41-year-old man presented with left hemiparesis. He had a giant thrombosed aneurysm at the basilar artery-superior cerebellar artery (BA-SCA) junction and a left extracranial VA aneurysm. A <i>de novo</i> VA fusiform aneurysm developed during a 1-month interval following the first session of intravascular coil embolization for the BA-SCA aneurysm. Stress on the fragile artery due to FMD during micro-catheterization may have caused the <i>de novo</i> aneurysm. An anomalous aortic origin of the left VA may also have played a role in the formation of the large <i>de novo</i> aneurysm and extracranial VA aneurysm. We performed overlapping stent-assisted coil embolization for the VA fusiform aneurysm using an Enterprise VRDs, and coil embolization for the BA-SCA thrombosed aneurysm using the stent-assisted technique with an Enterprise stent. Both aneurysms remained occluded for 7 years.</p><p><b>Conclusion:</b> We concluded micro-catheterization to be the cause of the large <i>de novo</i> aneurysm. This case emphasizes the importance of carefully performing intravascular interventional procedures for patients with FMD.</p>