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所属 |
大学院医学系研究科（医学専攻等） 医学専攻 病態制御医学系 救急・集中治療医学講座 |
職務経歴（学内） 【 表示 ／ 非表示 】
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2018年09月-継続中
秋田大学 大学院医学系研究科（医学専攻等） 医学専攻 病態制御医学系 准教授
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2016年09月-2018年08月
秋田大学 大学院医学系研究科（医学専攻等） 医学専攻 病態制御医学系 講師
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2013年04月-2016年08月
秋田大学 附属病院 集中治療部 助教
学会（学術団体）・委員会 【 表示 ／ 非表示 】
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2013年09月-継続中
日本国
日本外傷学会
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2013年04月-継続中
日本国
日本集中治療医学会
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2012年05月-継続中
日本国
日本災害医学会
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2010年03月-継続中
日本国
日本救急医学会
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1995年07月-継続中
日本国
日本外科学会
研究経歴 【 表示 ／ 非表示 】
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救急医学、集中治療医学
（選択しない）
研究期間：
2013年04月-継続中研究態様：機関内共同研究
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災害医療
（選択しない）
研究期間：
2010年01月-継続中研究態様：機関内共同研究
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食道癌治療
（選択しない）
研究期間：
2000年01月-2013年03月研究態様：機関内共同研究
学位論文 【 表示 ／ 非表示 】
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Soluble and cell-associated forms of some yet to be identified factor in transfused blood which promotes solid tumor growth in mice.
Motoyama S, Saito S, Saito R, Nakamura M, Imano H, Minamiya Y, Ogawa J
Surger Today 34 ( 8 ) 673 - 677 2003年03月
国内共著
研究等業績 【 表示 ／ 非表示 】
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Okura K.
Heart and Lung ( Heart and Lung ) 75 247 - 253 2026年01月
研究論文（学術雑誌）
BACKGROUND: Optimizing ventilatory management for lung and diaphragm protection is crucial in mechanically ventilated patients. Although monitoring inspiratory effort is useful, some ventilators lack this capability. Conversely, diaphragm thickening fraction (DTF) may serve as a surrogate index of respiratory effort. However, its optimal cutoff value remains unclear. OBJECTIVES: This study aimed to investigate the relationship between DTF and P0.1, as a measure of respiratory effort, and to identify the optimal DTF threshold for excessive respiratory effort. METHODS: This single-center, prospective, cross-sectional study included critically ill adults receiving invasive mechanical ventilation between June 2023 and May 2024. DTF was measured using ultrasound, while P0.1 was assessed via an airway occlusion maneuver using a ventilator's built-in tool. Potentially injurious respiratory effort was defined as ΔP0.1 > 3.5 cmH2O. Daily data were collected from the onset of spontaneous breathing. The optimal DTF cutoff was determined using receiver operating characteristic (ROC) and precision-recall (PR) curves, with the Youden index and F1 score. The prediction accuracy of DTF was evaluated using the area under the curve (AUC). RESULTS: A total of 174 daily recordings from 70 patients were analyzed. Twenty-three (13 %) recordings indicated potentially injurious respiratory effort. The AUC of the ROC and PR curves were 0.938 (95 % confidence interval [CI]: 0.848 to 0.994) and 0.857 (95 % CI: 0.667 to 0.952), respectively. The optimal DTF cutoff was 35.7 %, yielding 96.0 % accuracy, 87.0 % sensitivity, and 97.4 % specificity. CONCLUSION: DTF correlates with P0.1 in mechanically ventilated patients. A 35.7 % DTF cutoff accurately identifies potentially injurious respiratory effort.
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Association Between the Simplest Clinical Factors and Emergency Department Dispositions: A Retrospective Observational Study.
Kasumi Satoh, Manabu Okuyama, Hajime Nakae
Cureus 13 ( 1 ) e12844 2021年01月
研究論文（学術雑誌）
The emergency department (ED) is a complex and busy environment that requires rapid decision making. We assessed the relationship between disposition from the ED and information that can be obtained at a glance in the ED. The presentation of the implications of commonplace information could assist healthcare providers in ensuring smooth and safe ED care. Thus, we aimed to quantitatively assess how readily obtainable findings, such as age, sex, and vital signs, are involved in the disposition of adult patients transferred to the ED. This retrospective observational study was conducted in the ED of a regional university hospital containing approximately 600 beds. Of the 685 patients included in the analysis, 351 patients were admitted to the hospital (including 12 deaths in the ED) and 334 patients were discharged from the ED. A multiple logistic regression model that included age, sex, systolic blood pressure, heart rate, respiration rate, temperature, and SpO2 as variables identified independent associations between age (p=0.003), sex (p<0.001), systolic blood pressure (p=0.023), heart rate (p<0.001), and respiratory rate (p=0.028) and admission from the ED. The receiver operating characteristic curves drawn from the multiple logistic regression model comprising these five variables had an area under the curve (AUC) of 0.701 (95% confidence interval: 0.657-0.744, p<0.001). Examination of sensitivity, specificity, and likelihood ratios (LRs) for these five variables for clinical utility showed a slightly higher sensitivity for age ≥50 years (0.849) and respiratory rate ≥18 bpm (0.769); higher specificity for systolic blood pressure ≤100 mmHg (0.938), pulse rate ≥100 bpm (0.834), and respiratory rate ≥26 bpm (0.887); higher positive LR for systolic blood pressure ≤100 mmHg (2.039) and pulse rate ≥110 bpm (2.729); and slightly lower negative LR for age ≥50 years (0.656), male sex (0.647), respiratory rate ≥20 bpm (0.669). These results are meaningful as they quantify the intuition of a skilled clinician, which can help in clinical decision making, reduce errors, and promote clinical education. Our study provides a basis for explaining to novice healthcare providers that the careful observation of ED patients, even in the absence of special laboratory tests, can help them to make judgments regarding the disposition of the patients from the ED. In conclusion, age, sex, systolic blood pressure, heart rate, and respiratory rate were independently associated with a disposition from the ED. A multivariate model including these five variables showed the moderate-quality potential to predict admission from the ED. The sensitivity, specificity, and LR of systolic blood pressure, heart rate, and respiratory rate showed the characteristics of each vital sign. These provide healthcare providers in the ED an immediate clue regarding the patient's illness.
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The impact of organ dysfunctions on mortality in patients with severe sepsis: A multicenter prospective observational study.
Kudo D, Kushimoto S, Miyagawa N, Sato T, Hasegawa M, Ito F, Yamanouchi S, Honda H, Andoh K, Furukawa H, Yamada Y, Tsujimoto Y, Okuyama M.
Journal of Critical Care 2018年01月 [査読有り]
研究論文（学術雑誌） 国内共著
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Comparison of quality of human serum albumin preparations in two pharmaceutical products.
Nakae H, Tomida K, Kikuya Y, Okuyama M, Igarashi T
Acute Medicine & Surgery 2017年07月 [査読有り]
研究論文（学術雑誌） 国内共著
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A Case of Delirium Following Bear-Related Injury Treated With Yokukansan
Mishima T.
Traditional and Kampo Medicine ( Traditional and Kampo Medicine ) 13 ( 1 ) 2026年04月
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浸水想定区域の災害拠点病院における水害対応計画策定の現状と課題
山平 大介, 奥山 学, 内海 清乃, 石井 美恵子
日本災害医学会雑誌 ( 一般社団法人 日本災害医学会 ) 30 ( 4 ) 204 - 211 2025年12月
<p>【目的】浸水想定地域に位置する災害拠点病院の、水害による孤立を想定した病院内避難（籠城）に関する対応計画およびタイムラインの策定状況を調査し、課題を明らかにすることを目的とした。【方法】国土地理院のハザードマップを基に、浸水区域内の災害拠点病院328施設を抽出し、質問紙調査を実施した。有効回答のあった63施設を対象に、集計・分析を行った。【結果】対応計画策定済みの施設は41%、タイムライン策定済みの施設は19%であり、未策定の施設が半数以上を占めた。病院災害対策本部の設置や診療制限、患者対応に関する判断基準には施設間でばらつきがみられた。【考察】対応計画策定状況の差異には、災害リスク認識の違い、過去の被災経験、立地条件等が影響している可能性が考えられた。【結語】浸水想定地域内の災害拠点病院の多くで対応計画が未策定であり、風水害対策の標準化や策定支援を含む制度的整備が今後の課題であると考えられた。</p>
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Clinical features and treatments of VEXAS syndrome in critical care: a scoping review
Satoh K.
Critical Care ( Critical Care ) 29 ( 1 ) 2025年12月
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A case report of Kampo medicine use in severe mastitis
Saruta R.
Traditional and Kampo Medicine ( Traditional and Kampo Medicine ) 12 ( 1 ) 58 - 59 2025年04月
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Satoh K.
Therapeutic Apheresis and Dialysis ( Therapeutic Apheresis and Dialysis ) 2025年
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◆その他【 表示 ／ 非表示 】
科研費（文科省・学振）獲得実績 【 表示 ／ 非表示 】
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輸血が癌増殖に及ぼす影響。特に可溶性MHC classIの関与についての研究
基盤研究(C)
研究期間: 2005年04月 - 2007年03月