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職務経歴（学内） 【 表示 ／ 非表示 】
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2023年01月-継続中
秋田大学 附属病院 産科婦人科 講師
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2017年07月-2022年12月
秋田大学 大学院医学系研究科（医学専攻等） 医学専攻 機能展開医学系 産婦人科学講座 助教
学位論文 【 表示 ／ 非表示 】
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Retrieval and in vitro maturation of human oocytes from ovaries removed during surgery for endometrial carcinoma: a novel strategy for human oocyte research.
Shirasawa H, Kumagai J, Sato W, Kumazawa Y, Sato N, Terada Y
The Journal of Assisted Reproduction and Genetics 30 ( 9 ) 1227 - 1230 2015年03月
国内共著
研究等業績 【 表示 ／ 非表示 】
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Fact-finding survey on assisted reproductive technology in Japan
Harada S.
Journal of Obstetrics and Gynaecology Research ( Journal of Obstetrics and Gynaecology Research ) 49 ( 11 ) 2593 - 2601 2023年11月
研究論文（学術雑誌）
AIMS: In anticipation of the future development of assisted reproductive technology (ART) and to smoothly introduce new technology, it is necessary to understand the current staffing status of the medical system and the current state of treatment, as well as the status of in vitro fertilization add-ons, where the need for insurance coverage is currently a matter of debate. METHODS: ART facilities in Japan were surveyed (437 valid responses, response rate: 71%). Current staffing status of the medical system, implementation rates of ART, add-on treatments, and medical supplies were investigated. RESULTS: Despite the abundance of embryologists, nurses, and obstetricians and gynecologists in facilities, the majority of facilities lacked counselors, anesthesiologists, and other essential medical professionals. Conventional ovarian stimulation was widely adopted (median 120 [interquartile range 60-300] cycles), followed by mild ovarian simulation (60 [30-200]). Additionally, freeze-thaw embryo transfer cycles (300 [120-750]) were performed more frequently than fresh embryo transfer cycles (30 [30-60]). Among the add-ons, assisted hatching (85.1%), chronic endometritis examination (77.2%) and treatment (76.9%), artificial oocyte activation (67.3%), endometrial receptivity analysis (64.2%), and endometrial microbiome analysis (58.9%) were relatively widely employed. CONCLUSIONS: The implementation of frozen-thawed embryo transfer cycles, freeze-all strategies, and add-on treatments have become popular and widely accepted despite the lack of robust evidence regarding their safety and efficacy.
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Shirasawa H.
Heliyon ( Heliyon ) 9 ( 8 ) e19074 - e19074 2023年08月 [査読有り]
研究論文（学術雑誌）
RESEARCH QUESTION: How does the cost-related oocyte cryopreservation (OoC) vary by the facility in Japan, and what data is provided on the websites about OoC procedures? DESIGN: Website survey. The websites of all 621 facilities that provide assistive reproductive technology registered in Japan were surveyed in 2021. Data included the rates of explicit statements regarding the provision of OoC for only medical reasons (medical only group) or non-medical reasons (non-medical group). Based on whether or not facilities that perform OoC clearly stated the cost on their websites, we compared the costs of OoC and annual storage cost between medical only and non-medical groups. Furthermore, we examined the stated number of OoC procedures performed and their clinical outcomes. RESULTS: Of the 621 facilities, 146 (23.5%) clearly stated that they offer OoC on their websites. Of the 88 medical only groups and 58 non-medical groups, 24 (27.3%) and 42 (72.4%) clearly stated the OoC cost, and 27 (30.7%) and 44 (75.9%) clearly states the annual oocyte storage cost, respectively. The OoC costs were significantly higher for the non-medical group than in the medical group. In the medical only group, the annual storage cost remained almost the same regardless of the number of oocytes, while in the non-medical group, the annual storage cost was 2-3 times higher than in the medical only group. Only 16 facilities (16/146, 11.0%) had mentioned the number of OoC procedures, and five facilities (3.4%) provided information on the clinical outcomes after OoC. CONCLUSION: Costs related to OoC are higher for the non-medical group in Japan. In addition, the websites contain scant information on the costs and clinical outcomes of OoC.
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Okabe M.
Reproductive Medicine and Biology ( Reproductive Medicine and Biology ) 22 ( 1 ) 2023年01月 [査読有り]
研究論文（学術雑誌）
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In vitro maturation of human immature oocytes for fertility preservation and research material
Shirasawa H., Terada Y
Reproductive Medicine and Biology 2017年06月 [査読有り] [招待有り]
研究論文（学術雑誌） 国内共著
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In vitro maturation and cryopreservation of oocytes retrieved from intra-operative aspiration during second enucleation for ovarian tumor: A case report.
Shirasawa H, Kumazawa Y, Sato W, Ono N, Terada Y
Gynecologic Oncology Reports 19 1 - 4 2016年12月 [査読有り]
研究論文（学術雑誌） 国内共著
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若手の最新研究紹介コーナー ヒト卵子凍結におけるコヒーシン蛋白関連の加齢性変化と、卵子凍結安全性に関する検討(2016~2019年度 文部科学省科学研究費補助金採択研究)
白澤 弘光
産科と婦人科 85 ( 8 ) 970 - 972 2018年08月
総説・解説（商業誌）
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施設背景を考慮したメディカル・ノンメディカル卵子凍結コストの公開ウェブサイト記載情報を用いた比較検討
白澤 弘光, 熊澤 由紀代, 佐藤 亘, 岩澤 卓也, 高橋 和政, 寺田 幸弘
日本生殖医学会雑誌 ( (一社)日本生殖医学会 ) 67 ( 4 ) 332 - 332 2022年10月
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Hirakawa T.
Human Reproduction ( Human Reproduction ) 37 ( 7 ) 1423 - 1430 2022年07月
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H Shirasawa, Y Kumazawa, W Sato, K Togashi, N Ono, A Fujishima, Y Terada
Human Reproduction ( Oxford University Press (OUP) ) 37 ( Supplement_1 ) 2022年06月
Abstract
Study question
In Japan, how much of freezing cost and the yearly storage cost of medical and social egg freezing for fertility preservation is clearly disclosed on the institution's website?
Summary answer
Of the 621 infertility treatment institutions, 146 listed egg freezing on their websites, 46 specified the freezing cost, and 71 specified the yearly storage cost.
What is known already
In Japan, from April 2022, standard assisted reproductive technology will be covered by insurance, but medical and social egg freezing will continue to be privately funded. Therefore, it is unclear how many facilities in Japan perform egg freezing. Furthermore, while the cost of freezing and yearly storage varies significantly from facility to facility, there has been no data comparing egg freezing among facilities in Japan or other countries. Therefore, we extracted data about freezing and storage cost from each institution's website and compared them for the first time.
Study design, size, duration
This study is a web-based survey in which a single board-certified specialist by Japan Society for Reproductive Medicine exhaustively browsed the websites of all 621 fertility treatment institutions in Japan in October 2021 and analyzed the implementation of egg freezing, freezing costs, and yearly storage costs of egg are clearly stated on the websites. The costs of drugs used for egg retrieval and ovarian stimulation were excluded.
Participants/materials, setting, methods
Of the 621 institutions, 88 institutions that clearly stated on their websites that they offer egg freezing for medical reasons were divided into a medical group, and 58 institutions that clearly stated that they offer egg freezing for only social reasons were divided into social group for statistical analysis. We compared the freezing and the yearly storage cost, respectively, whether it varies depending on the number of eggs or whether it is a fixed cost.
Main results and the role of chance
Of the 621 institutions, 146 (23.5%), 88 in the medical group and 58 in the social group, specified that they offer egg freezing. The percentages of clarification for freezing cost and yearly storage cost on the website were 27.3% and 30.7% in the medical group, 72.4%, and 75.9% in the social group, so the social group was higher in both cases (p < 0.01). The percentage of fixed costs for egg freezing was significantly lower in the social group (6/42, 14.3%) than in the medical group (9/24, 37.5%) (p < 0.05). The percentage of fixed costs for yearly storage cost was samely significantly lower in the social group (30/44, 68.2%) than in the medical group (25/27, 92.6%) (p < 0.05). The mean freezing cost/yearly storage cost was as follows for 1, 5, and 10 eggs. The medical group was (JPY45,527/JPY22,327, JPY65,179/JPY22,530, JPY90,311/JPY22,770), and the social group was (JPY56,822/JPY40,178, JPY88,429/JPY56,502, JPY136,550/JPY79,090), so the social group had the significantly highest amount of costs in each case. Note that JPY 10,000 is about EUR77.7. The most expensive clinic to store ten eggs was JPY500,000 (EUR3,883) per year, and the least university hospital was JPY 4,600 (EUR35.7) per year.
Limitations, reasons for caution
This survey was conducted by carefully browsing the facility's website, but since we did not confirm the information through questionnaires or e-mail, there is the possibility that the information may have been updated. Another limitation is that less than half of the medical groups list cost details on their websites.
Wider implications of the findings
This is the first report to analyze the cost of egg freezing in Japan using the institution's website. The rate of cost disclosure on the website is still low. Moreover, the costs of social freezing are significantly higher than medical reasons, but this may change with the insurance of ART.
Trial registration number
not applicable -
第1極体放出からICSIまで20時間 卵巣組織凍結時の体外成熟培養(OTO-IVM)におけるタイムラプス観察意義
白澤 弘光, 熊澤 由紀代, 高橋 和政, 佐藤 亘, 尾野 夏紀, 後藤 真由美, 藤島 綾香, 寺田 幸弘
Journal of Mammalian Ova Research ( (一社)日本卵子学会 ) 39 ( 1 ) S60 - S60 2022年05月
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ヒト6日目胚盤胞径は栄養外胚葉構成細胞の遺伝学的均一性を反映する
長谷川 久隆, 岩澤 卓也, 富樫 嘉津恵, 牧野 健一, 白澤 弘光, 三浦 広志, 佐藤 亘, 熊澤 由紀代, 小林 淳一, 寺田 幸弘
日本産科婦人科学会雑誌 ( (公社)日本産科婦人科学会 ) 74 ( 臨増 ) S - 356 2022年02月
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◆総説・解説【 表示 ／ 非表示 】
◆その他【 表示 ／ 非表示 】
学術関係受賞 【 表示 ／ 非表示 】
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日本卵子学会学術奨励賞
2017年06月02日 日本卵子学会
受賞者： 白澤弘光 -
日本生殖医学会学術奨励賞
2016年11月03日 日本生殖医学会
受賞者： 白澤弘光 -
秋田医学会学術奨励賞
2016年02月29日 秋田医学会
受賞者： 白澤弘光
科研費（文科省・学振）獲得実績 【 表示 ／ 非表示 】
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ウェブ情報を踏まえた本邦の持続可能な配偶子凍結保存スキームの基盤研究
持続可能な社会保障への貢献
研究期間: 2022年 - 2023年
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月経血・帯下を用いた子宮内環境評価及び バイオマーカー検出を目的とした基盤研究
月経血・帯下を用いた子宮内環境評価及び バイオマーカー検出を目的とした基盤研究
研究期間: 2020年04月 - 2020年04月
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ヒト未成熟卵から単為発生胚にいたる動的解析と個体加齢および染色体分配異常の関連性
基盤研究(C)
研究期間: 2019年04月 - 2022年03月 代表者: 白澤 弘光
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ヒト卵子凍結におけるコヒーシン蛋白関連の加齢性変化と、卵子凍結安全性に関する検討
若手研究(B)
研究期間: 2016年04月 - 継続中
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ヒト卵子における減数分裂制御蛋白の個体加齢による発現量変化に関する研究
若手研究(B)
研究期間: 2013年04月 - 2015年03月
その他競争的資金獲得実績 【 表示 ／ 非表示 】
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手術時摘出卵巣からの卵胞液輸送プロセスにおける回収卵子に関する成績の比較検討
提供機関: 秋田大学 平成28年度秋田大学若手研究者支援事業
研究期間： 2016年09月 - 2017年03月
資金支給機関区分：その他
学会等発表 【 表示 ／ 非表示 】
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First comparison of the egg freezing and storage cost between medical adaptation and social adaptation of Japan fertility hospitals and clinics based on institution's websites
H. Shirasawa, Y. Kumazawa, W. Sato, K. Togashi, N. Ono, A. Fujishima, Y. Terada
ESHRE 38th Annual Meeting 2022年07月 - 2022年07月
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施設ホームページから得た医学的・社会的卵子凍結の実施有無および凍結コストに関する比較検討
白澤弘光, 熊澤由紀代, 佐藤亘, 富樫嘉津恵, 尾野夏紀, 藤島綾香, 寺田幸弘
第12回日本がん・生殖医療学会学術講演会 2022年02月 - 2022年02月
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Hiromitsu Shirasawa, Ph.D, M, D, Yukiyo Kumazawa, Ph.D., M, D, Wataru Sato, Ph.D., M, D, Kazumasa Takahashi, Ph, D, Kazue Togashi, Ph.D., M, D, Yukihiro Terada, Ph.D., M, D
ASRM 2021 Scientific congress & expo 2021年10月 - 2021年10月
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Step-by-step experience cases selection based on the number of experienced hysteroscopic surgeries and preoperative myoma diameter
Hiromitsu Shirasawa, Yukiyo Kumazawa, Wataru Sato, Kazue Togashi, Ayaka Fujishima, Yukihiro Terada
21st APAGE Annual Congress 2021年09月 - 2021年09月
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First trial evaluating antibodies against SARS-CoV-2 in menstrual blood collected from a sanitary napkin.
Shirasawa Hiromitsu, Kumazawa Yukiyo, Sato Wataru, Togashi Kazue, Waga Masato, Kushima Sshiori, Goto Mayumi, Sato Emiko, Takahashi Kazumasa, Terada Yukihiro
第73回日本産科婦人科学会学術講演会 ISP-23-9 2021年04月 - 2021年04月
学会・委員会等活動 【 表示 ／ 非表示 】
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日本生殖医学会
2023年03月-継続中The 25th IFFS World Congress 組織委員会財務委員会 幹事
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日本生殖医学会
2022年01月-継続中生殖医療の必修知識2023製作委員会委員
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厚生労働科学研究費
2022年-継続中「本邦の配偶子、胚管理に関する関連4学会による統一提言作成」研究班 研究分担者
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日本癌治療学会
2021年10月-継続中『小児，思春期・若年がん患者の妊孕性温存に関する診療ガイドライン』改訂WG委員
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日本産科婦人科学会
2021年06月-継続中生殖・内分泌委員会幹事